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Compatibility of Bowtie1 (v1.2.0 or later) with Tophat2 #138

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rason81 opened this issue Sep 4, 2023 · 1 comment
Open

Compatibility of Bowtie1 (v1.2.0 or later) with Tophat2 #138

rason81 opened this issue Sep 4, 2023 · 1 comment

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@rason81
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rason81 commented Sep 4, 2023

bowtie1 with versions greater than 1.2.0 are not compatible with Tophat (v2.1.1), reporting things like "./SeqAn-1.4.2/seqan/basic/basic_exception.h:236 FAILED! (Uncaught exception of type St11logic_error: basic_string::_S_construct NULL not valid)".
Possibly this issue is related to generation of *_genome.bwt.samheader.sam, because recent bowtie versions cannot generate sam headers with the empty input.
Although there is alternative for Tophat, it is still at some point the optimal one.
So, how to fix this issue?

@rason81 rason81 changed the title Comparability of Bowtie1 (v1.2.0 or later) with Tophat2 Compatibility of Bowtie1 (v1.2.0 or later) with Tophat2 Sep 4, 2023
@yuanlizhanshi
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i encountered the same problem, how did you slove this?

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