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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="utf-8">
<title>Nagarajan Lab @ Genome Institute of Singapore</title>
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
<meta name="description" content="Nagarajan Lab Webpage" />
<meta name="author" content="Niranjan Nagarajan" />
<!-- css -->
<link href="css/bootstrap.min.css" rel="stylesheet" />
<link href="css/fancybox/jquery.fancybox.css" rel="stylesheet">
<link href="css/jcarousel.css" rel="stylesheet" />
<link href="css/flexslider.css" rel="stylesheet" />
<link href="css/style.css" rel="stylesheet" />
<!-- Theme skin -->
<link href="skins/default.css" rel="stylesheet" />
<!-- HTML5 shim, for IE6-8 support of HTML5 elements -->
<!--[if lt IE 9]>
<script src="http://html5shim.googlecode.com/svn/trunk/html5.js"></script>
<![endif]-->
</head>
<body>
<div id="wrapper">
<!-- start header -->
<header>
<div class="navbar navbar-default navbar-static-top">
<div class="container">
<div class="navbar-header">
<button type="button" class="navbar-toggle" data-toggle="collapse" data-target=".navbar-collapse">
<span class="icon-bar"></span>
<span class="icon-bar"></span>
<span class="icon-bar"></span>
</button>
<a class="navbar-brand" href="index.html"><span>N</span>agarajan Lab</a>
</div>
<div class="navbar-collapse collapse ">
<ul class="nav navbar-nav">
<li><a href="index.html">Home</a></li>
<li class="dropdown">
<a href="research_overview.html" class="dropdown-toggle " data-toggle="dropdown" data-hover="dropdown" data-delay="0" data-close-others="false">Research <b class=" icon-angle-down"></b></a>
<ul class="dropdown-menu">
<li><a href="computational_genomics.html">Computational Genomics</a></li>
<li><a href="microbiome_studies.html">Microbiome Studies</a></li>
<li><a href="personalized_cancer_omics.html">Personalized Cancer Omics</a></li>
</ul>
</li>
<li><a href="publications.html">Publications</a></li>
<li><a href="software.html">Software</a></li>
<li class="active"><a href="people.html">People</a></li>
<li><a href="contact.html">Contact</a></li>
</ul>
</div>
</div>
</div>
</header>
<!-- end header -->
<section id="inner-headline">
<div class="container">
<div class="row">
<div class="col-lg-12">
<ul class="breadcrumb">
<li><a href="#"><i class="fa fa-home"></i></a><i class="icon-angle-right"></i></li>
<li>People</a></li>
</ul>
</div>
</div>
</div>
</section>
<!-- add page specific text here -->
<section id="content">
<div class="container">
<ul class="nav nav-tabs">
<li class="active"><a href="#Current" data-toggle="tab"><i class="icon-briefcase"></i> Current Members</a></li>
<li><a href="#Former" data-toggle="tab">Former Members</a></li>
<li><a href="#Interns" data-toggle="tab">Interns</a></li>
<li><a href="#Jobs" data-toggle="tab">Open Positions</a></li>
</ul>
<div class="tab-content">
<div class="tab-pane active" id="Current">
<div class="row">
<div class="col-xs-12 col-lg-6">
<img src="img/people/niranjan.jpg" height="140" width="140" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Niranjan Nagarajan (Principal Investigator)</b></li>
<li>B.A. in Computer Sci. & Mathematics (<a href="http://www.owu.edu">Ohio Wesleyan</a>, 2000)</li>
<li>Ph.D. in <a href="http://www.cs.cornell.edu">Comp. Sci.</a> (<a href="http://www.cornell.edu">Cornell Univ.</a>, 2006; Advisor: <a href="http://www.maths.usyd.edu.au/u/uri/">Uri Keich</a>)</li>
<li>Postdoctoral Fellowship in <a href="http://www.cbcb.umd.edu">CBCB</a> (UMD, Advisor: <a href="http://www.cbcb.umd.edu/~mpop/">Mihai Pop</a>)</li>
<li>Profiles: <a href="https://scholar.google.com/citations?user=s65iHisAAAAJ&hl=en">Google Scholar</a>, <a href="https://sg.linkedin.com/in/niranjan-nagarajan-765151ba">LinkedIn</a></li>
</ul>
</div>
<div class="col-xs-12 col-lg-6">
<img src="img/people/denis.jpg" height="140" width="140" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Denis Bertrand (Staff Scientist)</b></li>
<li>M.S. in Computer Sci. (<a href="http://www.fdsweb.univ-montp2.fr/">UM2</a>, 2002)</li>
<li>Ph.D. in <a href="http://www.lirmm.fr/lirmm_eng">Comp. Biol.</a> (<a href="http://www.fdsweb.univ-montp2.fr">UM2</a>, 2005; Advisor: <a href="https://research.pasteur.fr/en/member/olivier-gascuel/">Olivier Gascuel</a>)</li>
<li>Postdoctoral Fellowship in <a href="http://en.diro.umontreal.ca/home/">DIRO</a> (<a href="http://www.umontreal.ca/english/index.html">UDM</a>, Advisor: <a href="http://www.iro.umontreal.ca/~mabrouk/index-anglais.html">Nadia El-Mabrouk</a>)</li>
<li>Profiles: <a href="https://scholar.google.fr/citations?hl=fr&user=s31gtXkAAAAJ&sortby=pubdate">Google Scholar</a></li>
</ul>
</div>
</div>
<div class="row">
<div class="col-xs-12 col-lg-6">
<img src="img/people/shenyang.jpg" height="140" width="140" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Shen Yang (Staff Scientist)</b></li>
<li>M.S. in Biochemistry (Sun Yat Sen Univ., 2005)</li>
<li>Ph.d in Biochemistry (Sun Yat Sen Univ., Joint-Ph.D Student Scholarship of China Scholarship Council, <a href="http://pondside.uchicago.edu/ecol-evol/">Dept. of Ecol & Evol, Univ. of Chicago</a>, 2009, Advisor: <a href="http://pondside.uchicago.edu/ecol-evol/people/wu.html">Chung-I Wu</a>)</li>
<li>Profiles: <a href="https://scholar.google.com.sg/citations?user=aXQLJ5kAAAAJ&sortby=pubdate">Google Scholar</a></li>
</ul>
</div>
<div class="col-xs-12 col-lg-6">
<img src="img/people/jayce.jpg" height="140" width="140" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Koh Jia Yu Jayce (Bioinformatics Analyst)</b></li>
<li>B.Eng. in Bioengineering (<a href="http://www.nus.edu.sg/">NUS</a>, 2010)</li>
<li>M.S. in Statistics (<a href="http://www.nus.edu.sg">NUS</a>, 2013)</li>
</ul>
</div>
</div>
<div class="row">
<div class="col-xs-12 col-lg-6">
<img src="img/people/chenhao.jpg" height="140" width="140" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Li Chenhao (Graduate Student)</b></li>
<li>B.S. (Hons.) in Comp. Biol. (<a href="http://www.nus.edu.sg/">NUS</a>, 2014)</li>
<li>Ph.D. in Computer Sci., (<a href="http://www.comp.nus.edu.sg/">NUS SoC</a>, 2015-present)</li>
</ul>
</div>
<div class="col-xs-12 col-lg-6">
<img src="img/people/nok.jpg" height="140" width="140" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Suphavilai Chayaporn (Graduate Student)</b></li>
<li>B.S. in Computer Sci. (<a href="http://www.ku.ac.th/">Kasetsart University</a>, 2011)</li>
<li>M.S. in Computer Sci. (<a href="http://cs.iupui.edu/">Purdue University</a>, 2014)</li>
<li>Ph.D. in Computer Sci. (<a href="http://www.comp.nus.edu.sg/">NUS SoC</a>, 2015-present) </li>
</ul>
</div>
</div>
<div class="row">
<div class="col-xs-12 col-lg-6">
<img src="img/people/amanda.jpg" height="140" width="140" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Ng Hui Qi Amanda (Research Officer)</b><li>
<li>B.S. (Hons.) in Biological Sci. (<a href="http://www.ntu.edu.sg/Pages/home.aspx">NTU</a>, 2013)</li>
</ul>
</div>
</div>
<!-- <div class="row">
add new people
</div> -->
</div>
<div class="tab-pane" id="Former">
<!-- <div class="row"> -->
<div class="row">
<div class="col-xs-12 col-sm-6 col-lg-6">
<img src="img/people/song.jpg" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Gao Song (Graduate Student)</b></li>
<li>Current Position: <a href="https://www.sahmri.com/our-research/themes/heart-health/theme/our-team/dr-song-gao" target="_blank">EMBL Australia post-doctoral researcher</a></li>
</ul>
</div>
<div class="col-xs-12 col-sm-6 col-lg-6">
<img src="img/people/juntao.jpg" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Li Juntao (Research Fellow)</b></li>
<li>Current Position: <a href="https://sg.linkedin.com/in/juntao-li-02316820" target="_blank">Biostatistician (Lundbeck, Singapore)</a></li>
</ul>
</div>
</div>
<div class="row">
<div class="col-xs-12 col-sm-6 col-lg-6 ">
<img src="img/people/esther.png" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Boey Jia Hui Esther (Research Officer)</b><li>
<li>Current Position: <a href="https://www.linkedin.com/in/esther-boey-278b4751/" target="_blank">MOH</a></li>
</ul>
</div>
<div class="col-xs-12 col-sm-6 col-lg-6">
<img src="img/people/burton.jpg" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Burton Chia (Bioinformatics Analyst)</b></li>
<li>Current Position: <a href="https://sg.linkedin.com/in/burton-chia-50936832" target="_blank"> Bioinformatics Analyst (NCCS)</a></li>
</ul>
</div>
</div>
<div class="row">
<div class="col-xs-12 col-sm-6 col-lg-6">
<img src="img/people/andreas.jpg" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Andreas Wilm (Post-doctoral Fellow)</b></li>
<li>Current Position: <a href="https://scholar.google.com/citations?user=V8Ueo9cAAAAJ" target="_blank">Team Leader (RPD, GIS)</a></li>
</ul>
</div>
<!-- </div> -->
<!-- <div class="row"> -->
<div class="col-xs-12 col-sm-6 col-lg-6">
<img src="img/people/vinutha.jpg" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Vinutha Kukkillaya (Bioinformatics Specialist)</b></li>
<li>Current Position: <a href="https://" target="_blank"></a></li>
</ul>
</div>
</div>
<div class="row">
<div class="col-xs-12 col-sm-6 col-lg-6">
<img src="img/people/sun_miao.jpg" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Sun Miao (Research Fellow)</b></li>
<li>Current Position: <a href="https://sg.linkedin.com/in/miao-sun-38982422">Bioinformatics Scientist (Human Longevity)</a></li>
</ul>
</div>
<div class="col-xs-12 col-sm-6 col-lg-6">
<img src="img/people/davide.jpg" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Davide Verzotto (Post-doctoral Fellow)</b></li>
<li>Current Position: <a href="https://" target="_blank"></a></li>
</ul>
</div>
</div>
<div class="row">
<div class="col-xs-12 col-sm-6 col-lg-6">
<img src="img/people/kernrei.JPG" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Chng Kern Rei (Research Fellow)</b></li>
<li>Current Position: MOHH</li>
</ul>
</div>
<div class="col-xs-12 col-sm-6 col-lg-6">
<img src="img/people/guangxi.jpg" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Wu Guangxi (Post-doctoral Fellow)</b></li>
<li>Current Position: <a href="https://www.linkedin.com/in/guangxi-wu-bb35a750/">ORISE Fellow (USDA-ARS)</a></li>
</ul>
</div>
</div>
<div class="row">
<div class="col-xs-12 col-sm-6 col-lg-6">
<img src="img/people/tarini.jpg" height="100" width="100" class="pull-left" alt="" />
<ul style="list-style-type:none">
<li><b>Tarini Ghosh (Post-doctoral Fellow)</b> </li>
<li>Current Position:<a href="https://" target="_blank"></a></li>
</ul>
</div>
</div>
<!-- </div> -->
</div>
<div class="tab-pane" id="Interns">
<!-- <div class="row"> -->
<div class="row">
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/jessica.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b><a href="https://www.linkedin.com/in/jessicaque/" target="_blank">Jessica Que</a></b></li>
<li>BS in Univ. of British Columbia</li>
</ul>
</div>
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/siqi.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b>Wang Siqi</b></li>
<li>BS in Nanyang Tech. Univ.</li>
</ul>
</div>
<!-- </div> -->
<!-- <div class="row"> -->
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/grace.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b><a href="http://cgs.csail.mit.edu/team/" target="_blank">Grace Yeo</a></b></li>
<li>BS in Johns Hopkins; PhD in MIT</li>
</ul>
</div>
</div>
<div class="row">
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/scholar.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b>Sibyl Drissler</b></li>
<li>BS in Univ. of British Columbia</li>
</ul>
</div>
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/ankica.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b>Ankica Gogić</b></li>
<li>MS in Univ. of Zagreb</li>
</ul>
</div>
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/janja.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b><a href="https://www.linkedin.com/in/janja-paliska-ba9414aa/" target="_blank">Janja Paliska</a></b></li>
<li>MS in Univ. of Zagreb</li>
</ul>
</div>
</div>
<!-- </div> -->
<!-- <div class="row"> -->
<div class="row">
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/mirta.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b><a href="https://www.linkedin.com/in/mdvornicic/" target="_blank">Mirta Dvornicic</a></b></li>
<li>MS in Univ. of Zagreb</li>
</ul>
</div>
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/vanessa.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b><a href="https://www.linkedin.com/in/vanessa-%25C5%25BEupanovi%25C4%2587-7556a554/" target="_blank">Vanessa Županović</a></b></li>
<li>MS in Univ. of Zagreb</li>
</ul>
</div>
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/zia.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b><a href="https://www.linkedin.com/in/seyed-ziaeddin-alborzi-a2aaa238/" target="_blank">Ziaeddin Alborzi</a></b></li>
<li>PhD in IRIA (France)</li>
</ul>
</div>
</div>
<div class="row">
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/senthil.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b>Senthil Muthiah</b></li>
<li>PhD in UMD</li>
</ul>
</div>
<!-- </div> -->
<!-- <div class="row"> -->
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/anja.png" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b><a href="https://www.linkedin.com/in/anja-kiesel-04441988/" target="_blank">Anja Kiesel</a></b></li>
<li>PhD in Gene Center Munich</li>
</ul>
</div>
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/Ivan_Sovic.png" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b><a href="https://www.linkedin.com/in/isovic/" target="_blank">Ivan Sović</a></b></li>
<li>MS in Univ. of Zagreb</li>
</ul>
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<img src="img/people/filip.jpg" height="70" width="70" class="pull-left">
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<li><b><a href="https://www.linkedin.com/in/fhrenic/" target="_blank">Filip Hrenić</a></b></li>
<li>MS in Univ. of Zagreb</li>
</ul>
</div>
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/vedrana.jpg" height="70" width="70" class="pull-left">
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<li><b><a href="https://www.linkedin.com/in/vedrana-vazdar-2ab2a591/" target="_blank">Vedrana Vazdar</a></b></li>
<li>MS in Univ. of Zagreb</li>
</ul>
</div>
<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/scholar.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b>Kenneth Lim Kun Ming</b></li>
<li>BS in National Univ. of Singapore</li>
</ul>
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<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/Camille.JPG" height="70" width="70" class="pull-left">
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<li><b><a href="https://www.linkedin.com/in/camille-de-cevins-471a992b/" target="_blank">Camille de Cevins</a></b></li>
<li>MS in Université Paris Saclay</li>
</ul>
</div>
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<img src="img/people/Jim.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b>Jim Shaw</b></li>
<li>BS in Univ. of British Columbia</li>
</ul>
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<img src="img/people/Koonhan.jpg" height="70" width="70" class="pull-left">
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<li><b><a href="https://www.linkedin.com/in/koon-han-ong-b2149493/" target="_blank">Ong Koon Han</a></b></li>
<li>BAcc in Singapore Management Univ.</li>
</ul>
</div>
</div>
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<div class="col-xs-12 col-sm-4 col-lg-4">
<img src="img/people/JingChong.jpg" height="70" width="70" class="pull-left">
<ul style="list-style-type:none">
<li><b>Tan Jing Chong</b></li>
<li>BA in Univ. of Cambridge</li>
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<h6>SPLASH Graphical Abstract (Aw et al, 2016)</h6><img src="img/graphical abstracts/SPLASH graphical abstract.jpg" heigh="400" width="400">
<h6>PARTE Graphical Abstract (Wan et al, 2012)</h6><img src="img/graphical abstracts/PARTE graphical abstract.jpg" heigh="400" width="400">
</div>
<div class="col-sm-8">
<h4>1. Post-doctoral Fellowship in RNA Structural
Genomics</h4>
We are seeking highly qualified computational
scientists with expertise/interest in RNA structure
and biology. The Nagarajan Lab, in collaboration
with the Wan Lab at the Genome Institute of
Singapore are looking for applicants to direct
collaborative projects involving the development of
new algorithms and the analyis of novel
high-throughput, genome-scale RNA structure
datasets. Successfull candidates will work in a
highly inter-disciplinary environment to apply
cutting edge techniques in computational and
experimental genomics for achieving breakthrough
discoveries that significantly advance human health
and well-being.<br>
<br>RNA structure is fundamental to its function in
almost every cellular process and for understanding
disease biology. We have developed new approaches to
probe RNA secondary and tertiary structure
genome-wide [1-4] and are applying these for a range
of applications including (i) identification of new
targets for developing antibiotics against extremely
drug-resistant pathogens (ii) understanding
host-microbial interactions in diseases and (iii)
identifying structural switches that control gene
regulation during stem-cell differentiation and
oncogenesis. We are seeking exceptional researchers
who will join us in leveraging this unique
opportunity for significant basic and translational
advances in RNA genomics.<br>
<br>
<h6>References</h6>
<ol>
<li>Kertesz M*, Wan Y*, Mazor E, Rinn JL, Nutter RC, Chang HY, Segal E "Genome-wide measurement of RNA secondary structure in yeast." Nature 2010 Sep 2 ; 467(7311) : 103-7</li>
<li>Wan Y, Qu K, Ouyang Z, Kertesz M, Li J, Tibshirani R, Makino DL, Nutter RC, Segal E, Chang HY "Genome-wide measurement of RNA folding energies." Mol Cell 2012 Oct 26 ; 48(2) : 169-81 Epub 2012 Sep 13</li>
<li>Wan Y.*, Qu K.*, Zhang QF, Manor O, Ouyang Z, Zhang J, Snyder MP, Segal E and Chang HY "Landscape and variation of RNA secondary structure across the human transcriptome." Nature 2014 ; 505, 706–709</li>
<li>Aw JG, Shen Y, Wilm A, Sun M, Lim XN, Boon KL, Tapsin S, Chan YS, Tan CP, Sim AY, Zhang T, Susanto TT, Fu Z, Nagarajan N#, Wan Y# "In Vivo Mapping of Eukaryotic RNA Interactomes Reveals Principles of Higher-Order Organization and Regulation." Mol Cell 2016 May 19 ; 62(4) : 603-17 Epub 2016 May 12</li>
</ol>
<br>
<h6>Qualifications</h6>
<ul>
<li>PhD in Computational Biology/Computer Science/Applied Mathematics/Genomics</li>
<li>Strong analytical and programming skills (C/C++, perl/python, UNIX environment). Candidates with significant experience in RNA structure prediction will be strongly preferred.</li>
</ul>
<br>
<b>How To Apply:</b> E-mail cover letter, research statement, curriculum vitae, and contact details of at least three referees to Niranjan Nagarajan (<a href="mailto:[email protected]">[email protected]</a>) and Wan Yue (<a href="mailto:[email protected]">[email protected]</a>)
</div>
</div>
<hr>
<div class="row">
<div class="col-sm-4">
<h6>Eczema Model (Chng et al, 2016)</h6><img src="img/graphical abstracts/AD Model.jpg" heigh="400" width="400">
<h6><i>Malassezia</i> Phylogeny (Wu et al, 2015)</h6><img src="img/graphical abstracts/Malassezia Phylogeny.jpg" heigh="400" width="400">
</div>
<div class="col-sm-8">
<h4>2. Post-doctoral Fellowship in Skin Microbiome
Studies</h4> We are looking for genomics researchers
with a keen interest in studying the role of
microbes in skin diseases. The Nagarajan lab in the
Genome Institute of Singapore, in collaboration with
the Epithelial Biology group in the Institute of
Medical Biology are seeking candidates to lead
multiple projects studying the role of the
microbiome in inflammatory diseases of the skin
(e.g. eczema, psoriasis etc.). Successful candidates
will have the opportunity to design new studies in
close interaction with doctors and domain experts,
applying nextgen omics and analytical approaches to
understand the complex host-microbiome interactions
that lead to skin disease [1].<br>
<br>The role that microbes play on human skin is
still poorly understood despite characterization of
the diversity of habitats and niches that they
occupy [2]. This is particularly the case for skin
diseases which can affect a large proportion of the
population and have a significant impact on their
quality of life. We recently conducted a
metagenome-wide association study for eczema,
identifying key microbes and their likely functional
roles [1]. We are interested in extending this work
in several directions including (i) characterizing
the utility of pre-/probiotic therapies (ii)
developing in vitro and in silico models for
host-microbiome interactions [3] and (iii) studying the
role of fungi (e.g. Malassezia) on human skin [4].<br>
<br>
<h6>References</h6>
<ol>
<li>Chng KR, Tay ASL, Li C, Ng AHQ, Wang J, Suri BK, Matta AS, McGovern N, Janela B, Wong XFC, Sio YY, Au BV, Wilm A, De Sessions PF, Lim TC, Tang MBY, Ginhoux F, Connolly JE, Lane EB, Chew FT, Common JEA#, Nagarajan N# "Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare" Nature Microbiology 2016 1:16106 doi:10.1038/nmicrobiol.2016.106</li>
<li>Oh, J. et al. "Biogeography and individuality shape function in the human skin metagenome." Nature 2014 514, 59–64</li>
<li>Li C, Lim KM, Chng KR, Nagarajan N# "Predicting microbial interactions through computational approaches." Methods 2016 Jun 1 ; 102 : 12-9 Epub 2016 Mar 26</li>
<li>Wu G, Zhao H, Li C, Rajapakse MP, Wong WC, Xu J, Saunders CW, Reeder NL, Reilman RA, Scheynius A, Sun S, Billmyre BR, Li W, Averette AF, Mieczkowski P, Heitman J, Theelen B, Schröder MS, De Sessions PF, Butler G, Maurer-Stroh S, Boekhout T, Nagarajan N#, Dawson TL# "Genus-Wide Comparative Genomics of Malassezia Delineates Its Phylogeny, Physiology, and Niche Adaptation on Human Skin." PLoS Genet 2015 Nov ; 11(11) : e1005614 Epub 2015 Nov 5</li>
</ol>
<br>
<h6>Qualifications</h6>
<ul>
<li>PhD in Computational Biology/Computer Science/Applied Mathematics/Genomics</li>
<li>Strong analytical and programming skills (C/C++, perl/python, UNIX environment). Candidates with significant experience in Microbiome Studies or Skin Biology will be strongly preferred.</li>
</ul>
<br>
<b>How To Apply:</b> E-mail cover letter, research statement, curriculum vitae, and contact details of at least three referees to Niranjan Nagarajan (<a href="mailto:[email protected]">[email protected]</a>)
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<li><a href="https://www.a-star.edu.sg/imb/Research/tid/33/Hair-and-Skin-Health.aspx">Dr. Tom Dawson</a></li>
<li><a href="https://www.a-star.edu.sg/imb/Research/tid/29/Skin-Barrier.aspx">Dr. John Common</a></li>
<li><a href="http://www.pharmacy.nus.edu.sg/staff/phaccye/">Dr. Eric Chan</a></li>
<li><a href="https://www.ttsh.com.sg/patient-guide/find-care/specialists/page.aspx?spid=199">Dr. Barnaby Young</a></li>
<li><a href="https://www.a-star.edu.sg/gis/our-people/investigator-details.aspx?source=gis_fellows&user_id=147">Dr. Yue Wan</a></li>
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