diff --git a/fbdv-base.json b/fbdv-base.json
index 9e92afc..aa8f15d 100644
--- a/fbdv-base.json
+++ b/fbdv-base.json
@@ -1,6382 +1,8843 @@
{
- "graphs" : [ {
- "nodes" : [ {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005321",
- "meta" : {
- "definition" : {
- "val" : "Stages during which the germ band is extended - 9-12.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 260." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "extended germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005322",
- "meta" : {
- "definition" : {
- "val" : "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 250." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "rapidly extending germ band stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005320",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005314",
- "meta" : {
- "definition" : {
- "val" : "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "FlyBase:FBrf0039741" ]
- },
- "comments" : [ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "embryonic cycle 14 M-phase",
- "xrefs" : [ "FBC:DOS" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005315",
- "meta" : {
- "definition" : {
- "val" : "The 15th cell cycle of embryogenesis. Asynchronous.",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "second blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005312",
- "meta" : {
- "definition" : {
- "val" : "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "FlyBase:FBrf0049535", "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "first blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005313",
- "meta" : {
- "definition" : {
- "val" : "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "[FlyBase:FBrf0039741" ]
- },
- "comments" : [ "Temporal ordering number - 256." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "embryonic cycle 14 interphase",
- "xrefs" : [ "FBC:DOS" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005318",
- "meta" : {
- "definition" : {
- "val" : "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 230." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 6"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005319",
- "meta" : {
- "definition" : {
- "val" : "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 240." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005316",
- "meta" : {
- "definition" : {
- "val" : "The 16th cell cycle division of embryogenesis. Asynchronous.",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "third blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 16"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005317",
- "meta" : {
- "definition" : {
- "val" : "Stages during which gastrulation occurs. 6-8.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 220." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "gastrula",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "gastrula stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005310",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "cellular blastoderm stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005311",
- "meta" : {
- "definition" : {
- "val" : "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 210." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "cellular blastoderm stage",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "cellular blastoderm",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005303",
- "meta" : {
- "definition" : {
- "val" : "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 180." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005304",
- "meta" : {
- "definition" : {
- "val" : "Embryonic stages 4 and 5.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 160." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "blastoderm",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "blastoderm stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005301",
- "meta" : {
- "definition" : {
- "val" : "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 140." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005302",
- "meta" : {
- "definition" : {
- "val" : "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 150." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005307",
- "meta" : {
- "definition" : {
- "val" : "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 185." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005308",
- "meta" : {
- "definition" : {
- "val" : "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 190." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005305",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "syncytial blastoderm stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005306",
- "meta" : {
- "definition" : {
- "val" : "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 170." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "syncytial blastoderm stage",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "syncytial blastoderm",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 4"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym",
- "type" : "PROPERTY",
- "lbl" : "has_related_synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005309",
- "meta" : {
- "definition" : {
- "val" : "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 200." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007081",
- "meta" : {
- "definition" : {
- "val" : "6th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 860." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 6 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007080",
- "meta" : {
- "definition" : {
- "val" : "5th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 850." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 5 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007085",
- "meta" : {
- "definition" : {
- "val" : "10th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 900." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 10 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007084",
- "meta" : {
- "definition" : {
- "val" : "9th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 890." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 9 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007083",
- "meta" : {
- "definition" : {
- "val" : "8th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 880." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 8 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007082",
- "meta" : {
- "definition" : {
- "val" : "7th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 870." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 7 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007089",
- "meta" : {
- "definition" : {
- "val" : "14th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 940." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 14 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005340",
- "meta" : {
- "definition" : {
- "val" : "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 440." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-11-13T11:51:56Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "early third instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007088",
- "meta" : {
- "definition" : {
- "val" : "13th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 930." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 13 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007087",
- "meta" : {
- "definition" : {
- "val" : "12th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 920." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 12 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007086",
- "meta" : {
- "definition" : {
- "val" : "11th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 910." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 11 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005343",
- "meta" : {
- "definition" : {
- "val" : "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 510." ],
- "synonyms" : [ {
- "pred" : "hasNarrowSynonym",
- "val" : "pupal stage P0",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasNarrowSynonym",
- "val" : "white prepupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P1",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "puparium formation",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "white puparium stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "prepupal stage P1"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005344",
- "meta" : {
- "definition" : {
- "val" : "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 520." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P2",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "brown puparium stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P2"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005341",
- "meta" : {
- "definition" : {
- "val" : "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 460." ],
- "synonyms" : [ {
- "pred" : "hasBroadSynonym",
- "val" : "post-feeding larva",
- "xrefs" : [ ]
- }, {
- "pred" : "hasBroadSynonym",
- "val" : "late third instar",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-11-13T11:55:46Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "wandering third instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005342",
- "meta" : {
- "definition" : {
- "val" : "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 500." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005336",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 400." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005337",
- "meta" : {
- "definition" : {
- "val" : "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).",
- "xrefs" : [ "FlyBase:FBrf0007733" ]
- },
- "comments" : [ "Temporal ordering number - 410." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "L1",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "first instar larva",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "first instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005334",
- "meta" : {
- "definition" : {
- "val" : "Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 380." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 16"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005335",
- "meta" : {
- "definition" : {
- "val" : "Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 390." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 17"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005338",
- "meta" : {
- "definition" : {
- "val" : "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).",
- "xrefs" : [ "FlyBase:FBrf0007733" ]
- },
- "comments" : [ "Temporal ordering number - 420." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "L2",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "second instar larva",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "second instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005339",
- "meta" : {
- "definition" : {
- "val" : "The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).",
- "xrefs" : [ "FlyBase:FBrf0007733" ]
- },
- "comments" : [ "Temporal ordering number - 430." ],
- "synonyms" : [ {
- "pred" : "hasRelatedSynonym",
- "val" : "third instar larva",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "L3",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "third instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/IAO_0100001",
- "type" : "PROPERTY",
- "lbl" : "term replaced by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007078",
- "meta" : {
- "definition" : {
- "val" : "3rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 830." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 3 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007077",
- "meta" : {
- "definition" : {
- "val" : "2nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 820." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- },
- "type" : "CLASS",
- "lbl" : "day 2 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007076",
- "meta" : {
- "definition" : {
- "val" : "1st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 810." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 1 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007075",
- "meta" : {
- "definition" : {
- "val" : "The day of eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 780." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 0 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005332",
- "meta" : {
- "definition" : {
- "val" : "Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 360." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005333",
- "meta" : {
- "definition" : {
- "val" : "Embryonic stages 16-17.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 370." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "late embryonic stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005330",
- "meta" : {
- "definition" : {
- "val" : "Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 350." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "head involution stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007079",
- "meta" : {
- "definition" : {
- "val" : "4th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 840." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 4 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005331",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 13-15.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 330." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "dorsal closure stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005325",
- "meta" : {
- "definition" : {
- "val" : "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 310." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005326",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "contracted germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005323",
- "meta" : {
- "definition" : {
- "val" : "Stage 9 begins when mesodermal segmentation becomes (transiently) visible\\, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 280." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005324",
- "meta" : {
- "definition" : {
- "val" : "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 290." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005329",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0100001",
- "val" : "FBdv:00005330"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "head involution stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005327",
- "meta" : {
- "definition" : {
- "val" : "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 320." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "retracting germ band stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005328",
- "meta" : {
- "definition" : {
- "val" : "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 340." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "contracted germ band stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
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- "lbl" : "embryonic stage 13"
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- "type" : "PROPERTY",
- "lbl" : "has_alternative_id"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007023",
- "meta" : {
- "definition" : {
- "val" : "The M-phase (GO:0000279) of an embryonic cycle.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle M-phase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002012",
- "meta" : {
- "xrefs" : [ {
- "val" : "RO:0002012"
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- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "occurent_part_of"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- },
- "type" : "PROPERTY",
- "lbl" : "occurent_part_of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007022",
- "meta" : {
- "definition" : {
- "val" : "The interphase (GO:0051325) of an embryonic cycle.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "embryonic cycle interphase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007021",
- "meta" : {
- "definition" : {
- "val" : "The substage of the wandering third instar larval stage when the larva has cleared its gut contents.",
- "xrefs" : [ "FlyBase:FBrf0076598" ]
- },
- "comments" : [ "Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994." ],
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- "lbl" : "third instar - cleared gut stage"
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- "val" : "The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.",
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- },
- "comments" : [ "Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994)." ],
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- "lbl" : "third instar - partially cleared gut stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007026",
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- "definition" : {
- "val" : "Life stage from the end of adult stage A3, when tanning is complete, to death.",
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- },
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- "val" : "2013-01-10T13:03:54Z"
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- "type" : "CLASS",
- "lbl" : "mature adult stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007025",
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- "definition" : {
- "val" : "The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 782." ],
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- "val" : "2013-01-08T20:06:59Z"
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- },
- "type" : "CLASS",
- "lbl" : "immature adult stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007024",
- "meta" : {
- "xrefs" : [ {
- "val" : "GO:0008150"
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- "type" : "CLASS",
- "lbl" : "biological process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002131",
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- "val" : "overlaps"
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- "type" : "PROPERTY",
- "lbl" : "overlaps"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007019",
- "meta" : {
- "definition" : {
- "val" : "The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.",
- "xrefs" : [ "FlyBase:FBrf0076598" ]
- },
- "comments" : [ "Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994)." ],
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- "type" : "CLASS",
- "lbl" : "third instar - uncleared gut stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007018",
- "meta" : {
- "definition" : {
- "val" : "Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 394. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
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- "val" : "2011-04-26T12:03:14Z"
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- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 17(iv)"
- }, {
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- "type" : "PROPERTY",
- "lbl" : "synonym_type_property"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007017",
- "meta" : {
- "definition" : {
- "val" : "Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 393. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2011-04-26T12:01:18Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "djs93"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 17(iii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007012",
- "meta" : {
- "definition" : {
- "val" : "A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "synonyms" : [ {
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- "val" : "life cycle stage",
- "xrefs" : [ ]
- } ],
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- "val" : "2009-10-01T05:59:22Z"
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- }, {
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "life stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007133",
- "meta" : {
- "definition" : {
- "val" : "58th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1380." ],
- "basicPropertyValues" : [ {
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- },
- "type" : "CLASS",
- "lbl" : "day 58 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007132",
- "meta" : {
- "definition" : {
- "val" : "57th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1370." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 57 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007011",
- "meta" : {
- "definition" : {
- "val" : "A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.",
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- },
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- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007010",
- "meta" : {
- "basicPropertyValues" : [ {
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- "val" : "http://purl.obolibrary.org/obo/FBdv_00005259"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000231",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000227"
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- },
- "type" : "CLASS"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007131",
- "meta" : {
- "definition" : {
- "val" : "56th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1360." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "day 56 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007130",
- "meta" : {
- "definition" : {
- "val" : "55th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1350." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "type" : "CLASS",
- "lbl" : "day 55 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007016",
- "meta" : {
- "definition" : {
- "val" : "Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 392. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
- "basicPropertyValues" : [ {
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- "val" : "2011-04-26T12:00:15Z"
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- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 17(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007015",
- "meta" : {
- "definition" : {
- "val" : "The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
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- "val" : "2011-04-26T11:57:15Z"
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- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 17(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007135",
- "meta" : {
- "definition" : {
- "val" : "60th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1400." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "type" : "CLASS",
- "lbl" : "day 60 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007014",
- "meta" : {
- "definition" : {
- "val" : "Temporal subdivision of adulthood in days post-eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
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- "val" : "2010-09-29T12:28:05Z"
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- },
- "type" : "CLASS",
- "lbl" : "adult age in days"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007013",
- "meta" : {
- "definition" : {
- "val" : "Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.",
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- "lbl" : "age"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007134",
- "meta" : {
- "definition" : {
- "val" : "59th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1390." ],
- "basicPropertyValues" : [ {
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- "lbl" : "day 59 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00000054",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 1-4.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 25." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "cleavage stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007009",
- "meta" : {
- "xrefs" : [ {
- "val" : "GO:0032502"
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- "basicPropertyValues" : [ {
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2009-10-01T05:56:42Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "developmental process"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007008",
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- },
- "type" : "CLASS",
- "lbl" : "occurrent"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007129",
- "meta" : {
- "definition" : {
- "val" : "54th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1340." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 54 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007007",
- "meta" : {
- "definition" : {
- "val" : "Third instar larva from the beginning of wandering to the beginning of puparium formation.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 450." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-12-11T01:19:53Z"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
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- },
- "type" : "CLASS",
- "lbl" : "late third instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007128",
- "meta" : {
- "definition" : {
- "val" : "53rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1330." ],
- "basicPropertyValues" : [ {
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- "lbl" : "day 53 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007127",
- "meta" : {
- "definition" : {
- "val" : "52nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1320." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 52 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007006",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10250." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-11-13T06:27:57Z"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
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- "type" : "CLASS",
- "lbl" : "oogenesis stage S13E"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00004450",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 11 and 12.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 300." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
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- "type" : "CLASS",
- "lbl" : "late extended germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005300",
- "meta" : {
- "definition" : {
- "val" : "The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 130." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005412",
- "meta" : {
- "comments" : [ "This should be considered as a type of cell rather than as a stage. Please use FBbt:00005412." ],
- "basicPropertyValues" : [ {
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- "comments" : [ "Temporal ordering number - 10270." ],
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- "definition" : {
- "val" : "The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 625." ],
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- "definition" : {
- "val" : "Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.",
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- "comments" : [ "Temporal ordering number - 10240." ],
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- "comments" : [ "Temporal ordering number - 10260." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005288",
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- "comments" : [ "Temporal ordering number - 10." ],
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- "type" : "CLASS",
- "lbl" : "fertilized egg stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007104",
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- "definition" : {
- "val" : "29th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 1090." ],
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- "val" : "The stage of the Drosophila life-cycle from fertilization to hatching.",
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- "comments" : [ "Temporal ordering number - 20." ],
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- "val" : "28th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 1080." ],
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- "val" : "27th day after eclosion.",
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00006012",
- "meta" : {
- "definition" : {
- "val" : "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.",
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- "comments" : [ "Temporal ordering number - 800." ],
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- "val" : "adult stage III",
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- "val" : "FBdv:00005375"
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- },
- "type" : "CLASS",
- "lbl" : "adult stage A3"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005286",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.",
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005287",
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- "comments" : [ "Temporal ordering number - 10300." ],
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- "val" : "26th day after eclosion.",
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- "definition" : {
- "val" : "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.",
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- "lbl" : "oogenesis stage S10"
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- "definition" : {
- "val" : "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
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- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.",
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- "comments" : [ "Temporal ordering number - 10160." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005271",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.",
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- "comments" : [ "Temporal ordering number - 10110." ],
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- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.",
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- "comments" : [ "Temporal ordering number - 10120." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005277",
- "meta" : {
- "definition" : {
- "val" : "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.",
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005278",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.",
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- "comments" : [ "Temporal ordering number - 10200." ],
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- "type" : "CLASS",
- "lbl" : "oogenesis stage S13"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005275",
- "meta" : {
- "definition" : {
- "val" : "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
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- "comments" : [ "Temporal ordering number - 10170." ],
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- "lbl" : "oogenesis stage S12A"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005276",
- "meta" : {
- "definition" : {
- "val" : "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.",
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- "comments" : [ "Temporal ordering number - 10180." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005268",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
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- "comments" : [ "Temporal ordering number - 10080." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005269",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.",
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- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 490. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head an expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007105",
- "meta" : {
- "definition" : {
- "val" : "30th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1100." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 30 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007109",
- "meta" : {
- "definition" : {
- "val" : "34th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1140." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 34 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000062",
- "meta" : {
- "xrefs" : [ {
- "val" : "OBO_REL:preceded_by"
- }, {
- "val" : "BFO:0000062"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "preceded_by"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "preceded_by"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule",
- "type" : "PROPERTY",
- "lbl" : "namespace-id-rule"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002090",
- "meta" : {
- "xrefs" : [ {
- "val" : "RO:0002090"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "ends_at_start_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "ends_at_start_of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005361",
- "meta" : {
- "definition" : {
- "val" : "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 690." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005362",
- "meta" : {
- "definition" : {
- "val" : "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 700." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12(i)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "wing tips grey stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P12(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005360",
- "meta" : {
- "definition" : {
- "val" : "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 680." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "thoracic bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11(ii)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005365",
- "meta" : {
- "definition" : {
- "val" : "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 730." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P14",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "mature bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005366",
- "meta" : {
- "definition" : {
- "val" : "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 740." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P15",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005363",
- "meta" : {
- "definition" : {
- "val" : "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 710." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "wings grey stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12(ii)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P12(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005364",
- "meta" : {
- "definition" : {
- "val" : "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 720." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P13",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "wings black stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005358",
- "meta" : {
- "definition" : {
- "val" : "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 660." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005359",
- "meta" : {
- "definition" : {
- "val" : "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 670." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11(i)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "head bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005356",
- "meta" : {
- "definition" : {
- "val" : "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 640." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "amber-eyed stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P9",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005357",
- "meta" : {
- "definition" : {
- "val" : "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 650." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P10",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "red-eye bald stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_root_00000000",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0100001",
- "val" : "http://purl.obolibrary.org/obo/FBdv_00000000"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000231",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000227"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007092",
- "meta" : {
- "definition" : {
- "val" : "17th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 970." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 17 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007091",
- "meta" : {
- "definition" : {
- "val" : "16th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 960." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 16 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007090",
- "meta" : {
- "definition" : {
- "val" : "15th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 950." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 15 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007096",
- "meta" : {
- "definition" : {
- "val" : "21st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1010." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 21 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007095",
- "meta" : {
- "definition" : {
- "val" : "20th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1000." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 20 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007094",
- "meta" : {
- "definition" : {
- "val" : "19th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 990." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 19 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007093",
- "meta" : {
- "definition" : {
- "val" : "18th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 980." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 18 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005350",
- "meta" : {
- "definition" : {
- "val" : "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 580." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007099",
- "meta" : {
- "definition" : {
- "val" : "24th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1040." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 24 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005351",
- "meta" : {
- "definition" : {
- "val" : "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 590." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "Malpighian tubules migrating",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007098",
- "meta" : {
- "definition" : {
- "val" : "23rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1030." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 23 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007097",
- "meta" : {
- "definition" : {
- "val" : "22nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1020." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 22 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005354",
- "meta" : {
- "definition" : {
- "val" : "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 620." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "yellow body stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005355",
- "meta" : {
- "definition" : {
- "val" : "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 630." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "yellow-eyed stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P8",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 600." ],
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- "val" : "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
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- "comments" : [ "Temporal ordering number - 610." ],
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- "definition" : {
- "val" : "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
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- "val" : "buoyant stage",
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- "lbl" : "prepupal stage P4(i)"
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- "val" : "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
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- "comments" : [ "Temporal ordering number - 560." ],
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- "val" : "moving bubble stage",
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005345",
- "meta" : {
- "definition" : {
- "val" : "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
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- "comments" : [ "Temporal ordering number - 530." ],
- "synonyms" : [ {
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- "val" : "bubble prepupa stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
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- "val" : "pupal stage P3",
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- "lbl" : "prepupal stage P3"
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- "meta" : {
- "definition" : {
- "val" : "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
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- "comments" : [ "Temporal ordering number - 540." ],
- "synonyms" : [ {
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- "val" : "pupal stage P4",
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- "pred" : "hasExactSynonym",
- "val" : "cryptocephalic pupa",
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- "lbl" : "prepupal stage P4"
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- "val" : "The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).",
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- "lbl" : "database_cross_reference"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005262",
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- "val" : "Oogenesis stage that begins when the cyst leaves the germarium (from this point the cyst is referred to as an egg chamber). During this stage, polyploidation of the nurse cells begins, they reach a ploidy of 8C, and follicle cells start to divide.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
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- "comments" : [ "Temporal ordering number - 10020." ],
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- "lbl" : "oogenesis stage S2"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005263",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the oocyte chromosomes condense into a karyosome attached to a distinctive spherical structure known as an endobody. The oocyte nucleolus disappears completely. During this stage, nurse cell ploidy reaches 16C.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
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- "comments" : [ "Temporal ordering number - 10030." ],
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- "meta" : {
- "definition" : {
- "val" : "Earliest stage of ovarian cyst development - lasts while the 16 cell cyst is within the germarium (region 3).",
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- "comments" : [ "Temporal ordering number - 10010." ],
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- "type" : "CLASS",
- "lbl" : "oogenesis stage S1"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005266",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which follicle cell division ceases.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
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- "comments" : [ "Temporal ordering number - 10060." ],
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- "lbl" : "oogenesis stage S6"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005267",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which polyploidation and enlargement of follicle cells begins. Nurse cell ploidy ranges from 256C (anterior) to 512C (posterior) and the egg chamber gains an elongated shape.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
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- "comments" : [ "Temporal ordering number - 10070." ],
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- "lbl" : "oogenesis stage S7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00000000",
- "meta" : {
- "definition" : {
- "val" : "The life of an individual of the species Drosophila melanogaster, from fertilization to death.",
- "xrefs" : [ "FBC:DOS" ]
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- "synonyms" : [ {
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- "val" : "Drosophila life cycle",
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005264",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the nurse cells chromosomes become bulbous. Nurse cell chromosomes during this stage are polytene and reach a ploidy of 32C. The egg chamber is oval shaped.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
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- "comments" : [ "Temporal ordering number - 10040." ],
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- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when nurse cell chromosomes are no longer bulbous - the association between homologs weakens so that these chromosomes no longer have a polytene structure. During this stage, posterior nurse cell nuclei have a higher ploidy (64C) than anterior ones.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
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- "comments" : [ "Temporal ordering number - 10050." ],
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- "type" : "CLASS",
- "lbl" : "oogenesis stage S5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005259",
- "meta" : {
- "definition" : {
- "val" : "A temporal subdivision of a developmental process.",
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- "type" : "CLASS",
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- "meta" : {
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- "val" : "Newly eclosed adult stage. Animal free of pupal case. Runs rapidly to find site for wing expansion. Wings are folded back and black against a very pale abdomen.",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 785. The time at which eclosed flies settle down for wing expansion can vary greatly. If they fail to find a suitable site then expansion can be delayed by several hours." ],
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- "meta" : {
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- "val" : "Stage, shortly after eclosion, during which the wings expand. During wing expansion, the abdomen pulsates and the hind legs stroke the wings vigorously for several minutes at a time. The stage ends when the wings are folded down over the abdomen, which has become broader and shorter, and the wing cuticle has lost its folds. The stage lasts around 15 minutes at 25'C.",
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- },
- "comments" : [ "Temporal ordering number - 790." ],
- "synonyms" : [ {
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- "meta" : {
- "definition" : {
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- "comments" : [ "Temporal ordering number - 770." ],
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- "val" : "Tanning of the tergites obscures the Malpighian tubules and the 'yellow body'. Legs begin to twitch; fly is able to walk if puparium is removed prematurely. Ptilinum expands by hydrostatic pressure, opening the operculum. Duration at 25 degrees C: approximately 8 hours, 6 minutes. (211.5-219.6 hours after egg laying; 91.5-99.6 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 750." ],
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+ "Temporal ordering number - 10000."
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+ "comments": [
+ "Temporal ordering number - 10020."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the cyst leaves the germarium (from this point the cyst is referred to as an egg chamber). During this stage, polyploidation of the nurse cells begins, they reach a ploidy of 8C, and follicle cells start to divide.",
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+ "comments": [
+ "Temporal ordering number - 10030."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the oocyte chromosomes condense into a karyosome attached to a distinctive spherical structure known as an endobody. The oocyte nucleolus disappears completely. During this stage, nurse cell ploidy reaches 16C.",
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+ "comments": [
+ "Temporal ordering number - 10040."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the nurse cells chromosomes become bulbous. Nurse cell chromosomes during this stage are polytene and reach a ploidy of 32C. The egg chamber is oval shaped.",
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+ "comments": [
+ "Temporal ordering number - 10050."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell chromosomes are no longer bulbous - the association between homologs weakens so that these chromosomes no longer have a polytene structure. During this stage, posterior nurse cell nuclei have a higher ploidy (64C) than anterior ones.",
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+ "comments": [
+ "Temporal ordering number - 10060."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which follicle cell division ceases.",
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+ "comments": [
+ "Temporal ordering number - 10070."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which polyploidation and enlargement of follicle cells begins. Nurse cell ploidy ranges from 256C (anterior) to 512C (posterior) and the egg chamber gains an elongated shape.",
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+ "comments": [
+ "Temporal ordering number - 10080."
+ ],
+ "definition": {
+ "val": "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).",
+ "xrefs": [
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+ "comments": [
+ "Temporal ordering number - 10090."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.",
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+ "comments": [
+ "Temporal ordering number - 10100."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.",
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+ "comments": [
+ "Temporal ordering number - 10110."
+ ],
+ "definition": {
+ "val": "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.",
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+ "comments": [
+ "Temporal ordering number - 10120."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.",
+ "xrefs": [
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+ "comments": [
+ "Temporal ordering number - 10130."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
+ "xrefs": [
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+ "type": "CLASS"
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+ {
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+ ],
+ "comments": [
+ "Temporal ordering number - 10160."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.",
+ "xrefs": [
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+ "type": "CLASS"
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+ "comments": [
+ "Temporal ordering number - 10170."
+ ],
+ "definition": {
+ "val": "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
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+ {
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+ "comments": [
+ "Temporal ordering number - 10180."
+ ],
+ "definition": {
+ "val": "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
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+ "type": "CLASS"
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+ "comments": [
+ "Temporal ordering number - 10190."
+ ],
+ "definition": {
+ "val": "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.",
+ "xrefs": [
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+ "type": "CLASS"
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+ "lbl": "oogenesis stage S13",
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+ ],
+ "comments": [
+ "Temporal ordering number - 10200."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.",
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+ "type": "CLASS"
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+ "id": "http://purl.obolibrary.org/obo/FBdv_00005279",
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+ ],
+ "comments": [
+ "Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005280",
+ "lbl": "oogenesis stage S13B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10220. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which 9-11 nurse cell nuclei remain at the anterior of the oocyte. During this stage, the nuclear membrane of the oocyte nucleus disappears, indicating the start of meiotic pro-metaphase.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005281",
+ "lbl": "oogenesis stage S13C",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10230."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which only 7-8 nurse cell nuclei remain at the anterior of the oocyte. At the beginning of this stage, oocyte chromosome bivalents separate from each other - indicating mid-prometaphase of oocyte meiosis.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005282",
+ "lbl": "oogenesis stage S13D",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10240."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005283",
+ "lbl": "oogenesis stage S14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10260."
+ ],
+ "definition": {
+ "val": "The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005284",
+ "lbl": "oogenesis stage S14A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10270."
+ ],
+ "definition": {
+ "val": "Secretion and formation of the outer endochorionic network by throughout the follicle. Crystallization of the innermost chorionic layer of the main body follicle cells.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005285",
+ "lbl": "oogenesis stage S14B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10280."
+ ],
+ "definition": {
+ "val": "Secretion of the exochorion begins and ends.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005286",
+ "lbl": "egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10290."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.",
+ "xrefs": [
+ "FlyBase:FBrf0064779"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005287",
+ "lbl": "unfertilized egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10300."
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005288",
+ "lbl": "fertilized egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10."
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005289",
+ "lbl": "embryonic stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 20."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from fertilization to hatching.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005290",
+ "lbl": "pre-blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 30."
+ ],
+ "definition": {
+ "val": "Embryonic stage 1-3.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pre-blastoderm",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005291",
+ "lbl": "embryonic stage 1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 40."
+ ],
+ "definition": {
+ "val": "The embryonic stage that lasts from the end of fertilization to the end of the second nuclear division. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0064779",
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005292",
+ "lbl": "embryonic cycle 1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 50."
+ ],
+ "definition": {
+ "val": "The first mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005293",
+ "lbl": "embryonic stage 2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 70."
+ ],
+ "definition": {
+ "val": "Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005294",
+ "lbl": "embryonic cycle 2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 60."
+ ],
+ "definition": {
+ "val": "The second mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005295",
+ "lbl": "embryonic cycle 3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 80."
+ ],
+ "definition": {
+ "val": "The third mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005296",
+ "lbl": "embryonic cycle 4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 90."
+ ],
+ "definition": {
+ "val": "The fourth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005297",
+ "lbl": "embryonic cycle 5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 100."
+ ],
+ "definition": {
+ "val": "The fifth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005298",
+ "lbl": "embryonic cycle 6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 110."
+ ],
+ "definition": {
+ "val": "The sixth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005299",
+ "lbl": "embryonic cycle 7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 120."
+ ],
+ "definition": {
+ "val": "The seventh mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005300",
+ "lbl": "embryonic cycle 8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 130."
+ ],
+ "definition": {
+ "val": "The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005301",
+ "lbl": "embryonic stage 3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 140."
+ ],
+ "definition": {
+ "val": "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005302",
+ "lbl": "embryonic cycle 9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 150."
+ ],
+ "definition": {
+ "val": "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005303",
+ "lbl": "embryonic cycle 10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 180."
+ ],
+ "definition": {
+ "val": "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005304",
+ "lbl": "blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 160."
+ ],
+ "definition": {
+ "val": "Embryonic stages 4 and 5.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "blastoderm",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005305",
+ "lbl": "syncytial blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005306",
+ "lbl": "embryonic stage 4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 170."
+ ],
+ "definition": {
+ "val": "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "syncytial blastoderm",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "syncytial blastoderm stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005307",
+ "lbl": "embryonic cycle 11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 185."
+ ],
+ "definition": {
+ "val": "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005308",
+ "lbl": "embryonic cycle 12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 190."
+ ],
+ "definition": {
+ "val": "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005309",
+ "lbl": "embryonic cycle 13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 200."
+ ],
+ "definition": {
+ "val": "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005310",
+ "lbl": "cellular blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005311",
+ "lbl": "embryonic stage 5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 210."
+ ],
+ "definition": {
+ "val": "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular blastoderm",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular blastoderm stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005312",
+ "lbl": "embryonic cycle 14",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "FlyBase:FBrf0049535",
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "first blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005313",
+ "lbl": "embryonic cycle 14A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 256."
+ ],
+ "definition": {
+ "val": "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "[FlyBase:FBrf0039741"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonic cycle 14 interphase",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005314",
+ "lbl": "embryonic cycle 14B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "FlyBase:FBrf0039741"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonic cycle 14 M-phase",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005315",
+ "lbl": "embryonic cycle 15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 15th cell cycle of embryogenesis. Asynchronous.",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "second blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005316",
+ "lbl": "embryonic cycle 16",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 16th cell cycle division of embryogenesis. Asynchronous.",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "third blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005317",
+ "lbl": "gastrula stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 220."
+ ],
+ "definition": {
+ "val": "Stages during which gastrulation occurs. 6-8.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "gastrula",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005318",
+ "lbl": "embryonic stage 6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 230."
+ ],
+ "definition": {
+ "val": "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005319",
+ "lbl": "embryonic stage 7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 240."
+ ],
+ "definition": {
+ "val": "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005320",
+ "lbl": "germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005321",
+ "lbl": "extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 260."
+ ],
+ "definition": {
+ "val": "Stages during which the germ band is extended - 9-12.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005322",
+ "lbl": "embryonic stage 8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 250."
+ ],
+ "definition": {
+ "val": "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "rapidly extending germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005323",
+ "lbl": "embryonic stage 9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 280."
+ ],
+ "definition": {
+ "val": "Stage 9 begins when mesodermal segmentation becomes (transiently) visible\\, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005324",
+ "lbl": "embryonic stage 10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 290."
+ ],
+ "definition": {
+ "val": "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005325",
+ "lbl": "embryonic stage 11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 310."
+ ],
+ "definition": {
+ "val": "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005326",
+ "lbl": "contracted germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005327",
+ "lbl": "embryonic stage 12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 320."
+ ],
+ "definition": {
+ "val": "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "retracting germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005328",
+ "lbl": "embryonic stage 13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 340."
+ ],
+ "definition": {
+ "val": "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "contracted germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005329",
+ "lbl": "head involution stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "FBdv:00005330"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005330",
+ "lbl": "embryonic stage 14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 350."
+ ],
+ "definition": {
+ "val": "Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "head involution stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005331",
+ "lbl": "dorsal closure stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 330."
+ ],
+ "definition": {
+ "val": "A collective term for stages 13-15.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005332",
+ "lbl": "embryonic stage 15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 360."
+ ],
+ "definition": {
+ "val": "Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005333",
+ "lbl": "late embryonic stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 370."
+ ],
+ "definition": {
+ "val": "Embryonic stages 16-17.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005334",
+ "lbl": "embryonic stage 16",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 380."
+ ],
+ "definition": {
+ "val": "Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005335",
+ "lbl": "embryonic stage 17",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 390."
+ ],
+ "definition": {
+ "val": "Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005336",
+ "lbl": "larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 400."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005337",
+ "lbl": "first instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 410."
+ ],
+ "definition": {
+ "val": "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L1",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "first instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000000"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005338",
+ "lbl": "second instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 420."
+ ],
+ "definition": {
+ "val": "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L2",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "second instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000001"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005339",
+ "lbl": "third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 430."
+ ],
+ "definition": {
+ "val": "The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L3",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "third instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000002"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005340",
+ "lbl": "early third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T11:51:56Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 440."
+ ],
+ "definition": {
+ "val": "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005341",
+ "lbl": "wandering third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T11:55:46Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 460."
+ ],
+ "definition": {
+ "val": "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "late third instar",
+ "xrefs": []
+ },
+ {
+ "pred": "hasBroadSynonym",
+ "val": "post-feeding larva",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005342",
+ "lbl": "prepupal stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 500."
+ ],
+ "definition": {
+ "val": "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005343",
+ "lbl": "prepupal stage P1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 510."
+ ],
+ "definition": {
+ "val": "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P1",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "puparium formation",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "white puparium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "pupal stage P0",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "white prepupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005344",
+ "lbl": "prepupal stage P2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 520."
+ ],
+ "definition": {
+ "val": "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "brown puparium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P2",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005345",
+ "lbl": "prepupal stage P3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 530."
+ ],
+ "definition": {
+ "val": "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "bubble prepupa stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P3",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005346",
+ "lbl": "prepupal stage P4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 540."
+ ],
+ "definition": {
+ "val": "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cryptocephalic pupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005347",
+ "lbl": "prepupal stage P4(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 550."
+ ],
+ "definition": {
+ "val": "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "buoyant stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005348",
+ "lbl": "prepupal stage P4(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 560."
+ ],
+ "definition": {
+ "val": "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "moving bubble stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4(ii)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005349",
+ "lbl": "pupal stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 570. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for Cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head and expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage."
+ ],
+ "definition": {
+ "val": "The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "phanerocephalic pupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005350",
+ "lbl": "pupal stage P5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 580."
+ ],
+ "definition": {
+ "val": "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005351",
+ "lbl": "pupal stage P5(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 590."
+ ],
+ "definition": {
+ "val": "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "Malpighian tubules migrating",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005352",
+ "lbl": "pupal stage P5(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 600."
+ ],
+ "definition": {
+ "val": "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "white Malpighian tubules stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005353",
+ "lbl": "pupal stage P6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 610."
+ ],
+ "definition": {
+ "val": "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "green Malpighian tubules stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005354",
+ "lbl": "pupal stage P7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 620."
+ ],
+ "definition": {
+ "val": "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "yellow body stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005355",
+ "lbl": "pharate adult stage P8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 630."
+ ],
+ "definition": {
+ "val": "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P8",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "yellow-eyed stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005356",
+ "lbl": "pharate adult stage P9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 640."
+ ],
+ "definition": {
+ "val": "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "amber-eyed stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P9",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005357",
+ "lbl": "pharate adult stage P10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 650."
+ ],
+ "definition": {
+ "val": "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P10",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "red-eye bald stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005358",
+ "lbl": "pharate adult stage P11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 660."
+ ],
+ "definition": {
+ "val": "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005359",
+ "lbl": "pharate adult stage P11(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 670."
+ ],
+ "definition": {
+ "val": "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "head bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005360",
+ "lbl": "pharate adult stage P11(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 680."
+ ],
+ "definition": {
+ "val": "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11(ii)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "thoracic bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005361",
+ "lbl": "pharate adult stage P12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 690."
+ ],
+ "definition": {
+ "val": "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005362",
+ "lbl": "pharate adult stage P12(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 700."
+ ],
+ "definition": {
+ "val": "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12(i)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wing tips grey stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005363",
+ "lbl": "pharate adult stage P12(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 710."
+ ],
+ "definition": {
+ "val": "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12(ii)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wings grey stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005364",
+ "lbl": "pharate adult stage P13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 720."
+ ],
+ "definition": {
+ "val": "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P13",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wings black stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005365",
+ "lbl": "pharate adult stage P14",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 730."
+ ],
+ "definition": {
+ "val": "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "mature bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P14",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005366",
+ "lbl": "pharate adult stage P15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 740."
+ ],
+ "definition": {
+ "val": "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005367",
+ "lbl": "pharate adult stage P15(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 750."
+ ],
+ "definition": {
+ "val": "Tanning of the tergites obscures the Malpighian tubules and the 'yellow body'. Legs begin to twitch; fly is able to walk if puparium is removed prematurely. Ptilinum expands by hydrostatic pressure, opening the operculum. Duration at 25 degrees C: approximately 8 hours, 6 minutes. (211.5-219.6 hours after egg laying; 91.5-99.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "meconium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005368",
+ "lbl": "pharate adult stage P15(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 760."
+ ],
+ "definition": {
+ "val": "Stage which starts when the operculum opens and ends when eclosion is completed. Duration at 25 degrees C: approximately 24 minutes. (219.6-220 hours after egg laying; 99.6-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "eclosion stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15(ii)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005369",
+ "lbl": "adult stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 770."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from eclosion to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005370",
+ "lbl": "adult stage A1",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005373"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 785. The time at which eclosed flies settle down for wing expansion can vary greatly. If they fail to find a suitable site then expansion can be delayed by several hours."
+ ],
+ "definition": {
+ "val": "Newly eclosed adult stage. Animal free of pupal case. Runs rapidly to find site for wing expansion. Wings are folded back and black against a very pale abdomen.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage I",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005371",
+ "lbl": "adult stage A2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005374"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 790."
+ ],
+ "definition": {
+ "val": "Stage, shortly after eclosion, during which the wings expand. During wing expansion, the abdomen pulsates and the hind legs stroke the wings vigorously for several minutes at a time. The stage ends when the wings are folded down over the abdomen, which has become broader and shorter, and the wing cuticle has lost its folds. The stage lasts around 15 minutes at 25'C.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage II",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005412",
+ "lbl": "gamete",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "This should be considered as a type of cell rather than as a stage. Please use FBbt:00005412."
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00006011",
+ "lbl": "pharate adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 625."
+ ],
+ "definition": {
+ "val": "The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355",
+ "FlyBase:FBrf0049147"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00006012",
+ "lbl": "adult stage A3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005375"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 800."
+ ],
+ "definition": {
+ "val": "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage III",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007000",
+ "lbl": "spermatogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-06-05T04:51:08Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 20000."
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0007283"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007001",
+ "lbl": "P-stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-06-05T04:51:40Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 490. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head an expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "metamorphosis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "pupal stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007002",
+ "lbl": "oogenesis stage S11a",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10140."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins and ends when the dorsal appendages begin to form.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007003",
+ "lbl": "oogenesis stage S11b",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10150."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when endochorion begins to form at the anterior pole, a process which includes the beginning of formation of the dorsal appendages. During this stage, the follicle cells secrete membranous vesicles that form irregular extracellular plaques. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007004",
+ "lbl": "third instar larval stage L1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 470."
+ ],
+ "definition": {
+ "val": "Stage which begins when wandering third instar larva stops crawling. The larva everts its anterior spiracles during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007005",
+ "lbl": "third instar larval stage L2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 480."
+ ],
+ "definition": {
+ "val": "The anterior spiracles are fully everted, with 7-9 finger-like projections. The body shortens, withdrawing three apparent abdominal segments and the larva sticks to its substrate.",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "spiracles everted larva",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "white prepupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007006",
+ "lbl": "oogenesis stage S13E",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T06:27:57Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10250."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007007",
+ "lbl": "late third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-12-11T01:19:53Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 450."
+ ],
+ "definition": {
+ "val": "Third instar larva from the beginning of wandering to the beginning of puparium formation.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007008",
+ "lbl": "occurrent",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007009",
+ "lbl": "developmental process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:56:42Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0032502"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007011",
+ "lbl": "embryonic cycle",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:57:41Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.",
+ "xrefs": [
+ "FlyBase:FBrf0049535",
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007012",
+ "lbl": "life stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "djs93"
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:59:22Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "life cycle stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007013",
+ "lbl": "age",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-29T12:25:36Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007014",
+ "lbl": "adult age in days",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-29T12:28:05Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Temporal subdivision of adulthood in days post-eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007015",
+ "lbl": "embryonic stage 17(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T11:57:15Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007016",
+ "lbl": "embryonic stage 17(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:00:15Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 392. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007017",
+ "lbl": "embryonic stage 17(iii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:01:18Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 393. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007018",
+ "lbl": "embryonic stage 17(iv)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:03:14Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 394. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007019",
+ "lbl": "third instar - uncleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994)."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007020",
+ "lbl": "third instar - partially cleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994)."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007021",
+ "lbl": "third instar - cleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage when the larva has cleared its gut contents.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007022",
+ "lbl": "embryonic cycle interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The interphase (GO:0051325) of an embryonic cycle.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007023",
+ "lbl": "embryonic cycle M-phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The M-phase (GO:0000279) of an embryonic cycle.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007024",
+ "lbl": "biological process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0008150"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007025",
+ "lbl": "immature adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-01-08T20:06:59Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 782."
+ ],
+ "definition": {
+ "val": "The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007026",
+ "lbl": "mature adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-01-10T13:03:54Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Life stage from the end of adult stage A3, when tanning is complete, to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007075",
+ "lbl": "day 0 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 780."
+ ],
+ "definition": {
+ "val": "The day of eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007076",
+ "lbl": "day 1 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 810."
+ ],
+ "definition": {
+ "val": "1st day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007077",
+ "lbl": "day 2 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 820."
+ ],
+ "definition": {
+ "val": "2nd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007078",
+ "lbl": "day 3 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 830."
+ ],
+ "definition": {
+ "val": "3rd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007079",
+ "lbl": "day 4 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 840."
+ ],
+ "definition": {
+ "val": "4th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007080",
+ "lbl": "day 5 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 850."
+ ],
+ "definition": {
+ "val": "5th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007081",
+ "lbl": "day 6 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 860."
+ ],
+ "definition": {
+ "val": "6th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007082",
+ "lbl": "day 7 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 870."
+ ],
+ "definition": {
+ "val": "7th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007083",
+ "lbl": "day 8 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 880."
+ ],
+ "definition": {
+ "val": "8th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007084",
+ "lbl": "day 9 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 890."
+ ],
+ "definition": {
+ "val": "9th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007085",
+ "lbl": "day 10 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 900."
+ ],
+ "definition": {
+ "val": "10th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007086",
+ "lbl": "day 11 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 910."
+ ],
+ "definition": {
+ "val": "11th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007087",
+ "lbl": "day 12 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 920."
+ ],
+ "definition": {
+ "val": "12th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007088",
+ "lbl": "day 13 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 930."
+ ],
+ "definition": {
+ "val": "13th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007089",
+ "lbl": "day 14 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 940."
+ ],
+ "definition": {
+ "val": "14th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007090",
+ "lbl": "day 15 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 950."
+ ],
+ "definition": {
+ "val": "15th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007091",
+ "lbl": "day 16 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 960."
+ ],
+ "definition": {
+ "val": "16th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007092",
+ "lbl": "day 17 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 970."
+ ],
+ "definition": {
+ "val": "17th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007093",
+ "lbl": "day 18 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 980."
+ ],
+ "definition": {
+ "val": "18th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007094",
+ "lbl": "day 19 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 990."
+ ],
+ "definition": {
+ "val": "19th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
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+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007135",
+ "lbl": "day 60 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1400."
+ ],
+ "definition": {
+ "val": "60th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00014201",
+ "lbl": "early extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 270."
+ ],
+ "definition": {
+ "val": "A collective term for stages 9 and 10.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00018001",
+ "lbl": "substage_of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "substage_of"
+ }
+ ],
+ "comments": [
+ "Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO."
+ ],
+ "xrefs": [
+ {
+ "val": "FBdv:00018001"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002012",
+ "lbl": "occurent_part_of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "occurent_part_of"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002012"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002087",
+ "lbl": "immediately_preceded_by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "immediately_preceded_by"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002087"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002090",
+ "lbl": "ends_at_start_of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "ends_at_start_of"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002090"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002131",
+ "lbl": "overlaps",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "overlaps"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002131"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/fbdv#systematic_synonym",
+ "lbl": "Systematic synonym",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasScope",
+ "val": "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/IAO_0000115",
+ "lbl": "definition",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "lbl": "term replaced by",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule",
+ "lbl": "namespace-id-rule",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#SubsetProperty",
+ "lbl": "subset_property",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty",
+ "lbl": "synonym_type_property",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "lbl": "has_alternative_id",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym",
+ "lbl": "has_broad_synonym",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasDbXref",
+ "lbl": "database_cross_reference",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym",
+ "lbl": "has_exact_synonym",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym",
+ "lbl": "has_narrow_synonym",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion",
+ "lbl": "has_obo_format_version",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "lbl": "has_obo_namespace",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym",
+ "lbl": "has_related_synonym",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasScope",
+ "lbl": "has_scope",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "lbl": "shorthand",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005373",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000231",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000227"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00005370"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005374",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000231",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000227"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00005371"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005375",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000231",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000227"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00006012"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007010",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000231",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000227"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00005259"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_root_00000000",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000231",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000227"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00000000"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ }
+ ],
+ "propertyChainAxioms": []
+ }
+ ]
+}
diff --git a/fbdv-base.obo b/fbdv-base.obo
index 4faa9b0..90114c7 100644
--- a/fbdv-base.obo
+++ b/fbdv-base.obo
@@ -1,6 +1,6 @@
format-version: 1.2
-data-version: fbdv/releases/2021-01-13/fbdv-base.owl
-date: 13:01:2021 12:25
+data-version: fbdv/releases/2021-03-10/fbdv-base.owl
+date: 10:03:2021 10:38
subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation"
subsetdef: gocheck_do_not_manually_annotate "Term not to be used for direct manual annotation"
subsetdef: goslim_aspergillus "Aspergillus GO slim"
@@ -30,7 +30,7 @@ property_value: IAO:0000700 FBdv:00000000
property_value: IAO:0000700 FBdv:00005259
property_value: IAO:0000700 FBdv:00007013
property_value: IAO:0000700 FBdv:00007024
-property_value: owl:versionInfo "2021-01-13" xsd:string
+property_value: owl:versionInfo "2021-03-10" xsd:string
[Term]
id: FBdv:00000000
@@ -326,6 +326,7 @@ comment: Temporal ordering number - 10.
is_a: FBdv:00005259 ! developmental stage
relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
relationship: substage_of FBdv:00005286 ! egg stage
+relationship: substage_of FBdv:00005289 ! embryonic stage
[Term]
id: FBdv:00005289
@@ -333,7 +334,7 @@ name: embryonic stage
def: "The stage of the Drosophila life-cycle from fertilization to hatching." [FBC:DOS]
comment: Temporal ordering number - 20.
is_a: FBdv:00007012 ! life stage
-relationship: immediately_preceded_by FBdv:00005288 ! fertilized egg stage
+relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
[Term]
id: FBdv:00005290
@@ -779,6 +780,7 @@ def: "The first larval instar begins at hatching and ends at the first larval mo
comment: Temporal ordering number - 410.
synonym: "first instar larva" EXACT []
synonym: "L1" EXACT []
+xref: UBERON:8000000
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005289 ! embryonic stage
relationship: immediately_preceded_by FBdv:00005333 ! late embryonic stage
@@ -793,6 +795,7 @@ def: "The second larval instar begins at the first larval molt and ends at the s
comment: Temporal ordering number - 420.
synonym: "L2" EXACT []
synonym: "second instar larva" EXACT []
+xref: UBERON:8000001
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005337 ! first instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -804,6 +807,7 @@ def: "The third larval instar begins at the second larval molt and ends at pupar
comment: Temporal ordering number - 430.
synonym: "L3" EXACT []
synonym: "third instar larva" RELATED []
+xref: UBERON:8000002
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005338 ! second instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
diff --git a/fbdv-base.owl b/fbdv-base.owl
index 1dab9d6..6c2f857 100644
--- a/fbdv-base.owl
+++ b/fbdv-base.owl
@@ -12,7 +12,7 @@
xmlns:terms="http://purl.org/dc/terms/"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
-
+
@@ -26,10 +26,10 @@
https://creativecommons.org/licenses/by/3.0/
* FBdv:$sequence(8,7000,10000)$
- 13:01:2021 12:25
+ 10:03:2021 10:38
FlyBase_development_CV
1.2
- 2021-01-13
+ 2021-03-10
@@ -200,30 +200,6 @@
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
@@ -1497,6 +1473,12 @@
+
+
+
+
+
+
@@ -1518,7 +1500,7 @@
-
+
The stage of the Drosophila life-cycle from fertilization to hatching.
@@ -3079,6 +3061,7 @@
The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).
+ UBERON:8000000
L1
first instar larva
FlyBase_development_CV
@@ -3112,6 +3095,7 @@
The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).
+ UBERON:8000001
L2
second instar larva
FlyBase_development_CV
@@ -3145,6 +3129,7 @@
The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).
+ UBERON:8000002
L3
FlyBase_development_CV
third instar larva
diff --git a/fbdv-full.json b/fbdv-full.json
index 8ef0550..33865c6 100644
--- a/fbdv-full.json
+++ b/fbdv-full.json
@@ -1,10480 +1,14641 @@
{
- "graphs" : [ {
- "nodes" : [ {
- "id" : "http://purl.obolibrary.org/obo/GO_0003674",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "molecular process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "molecular_function"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0000280",
- "meta" : {
- "definition" : {
- "val" : "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.",
- "xrefs" : [ "GOC:mah" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ],
- "synonyms" : [ {
- "pred" : "hasRelatedSynonym",
- "val" : "karyokinesis",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "nuclear division"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005321",
- "meta" : {
- "definition" : {
- "val" : "Stages during which the germ band is extended - 9-12.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 260." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "extended germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005322",
- "meta" : {
- "definition" : {
- "val" : "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 250." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "rapidly extending germ band stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005320",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005314",
- "meta" : {
- "definition" : {
- "val" : "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "FlyBase:FBrf0039741" ]
- },
- "comments" : [ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "embryonic cycle 14 M-phase",
- "xrefs" : [ "FBC:DOS" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005315",
- "meta" : {
- "definition" : {
- "val" : "The 15th cell cycle of embryogenesis. Asynchronous.",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "second blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005312",
- "meta" : {
- "definition" : {
- "val" : "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "FlyBase:FBrf0049535", "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "first blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005313",
- "meta" : {
- "definition" : {
- "val" : "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "[FlyBase:FBrf0039741" ]
- },
- "comments" : [ "Temporal ordering number - 256." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "embryonic cycle 14 interphase",
- "xrefs" : [ "FBC:DOS" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005318",
- "meta" : {
- "definition" : {
- "val" : "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 230." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "type" : "CLASS",
- "lbl" : "embryonic stage 6"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005319",
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- "val" : "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).",
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- },
- "comments" : [ "Temporal ordering number - 240." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005316",
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- "val" : "The 16th cell cycle division of embryogenesis. Asynchronous.",
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- "comments" : [ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
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- "val" : "third blastoderm mitosis",
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- "lbl" : "embryonic cycle 16"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005317",
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- "definition" : {
- "val" : "Stages during which gastrulation occurs. 6-8.",
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- },
- "comments" : [ "Temporal ordering number - 220." ],
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- "val" : "gastrula",
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- "id" : "http://purl.obolibrary.org/obo/PATO_0000001",
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- "lbl" : "quality"
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- "id" : "http://purl.obolibrary.org/obo/GO_0016740",
- "type" : "CLASS",
- "lbl" : "transferase activity"
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- "id" : "http://purl.obolibrary.org/obo/RO_0002608",
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- "definition" : {
- "val" : "Inverse of 'causal agent in process'",
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
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- },
- "type" : "PROPERTY",
- "lbl" : "process has causal agent"
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- "id" : "http://purl.obolibrary.org/obo/RO_0002286",
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- "val" : "Inverse of developmentally preceded by",
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
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- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
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- },
- "type" : "PROPERTY",
- "lbl" : "developmentally succeeded by"
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- "type" : "CLASS",
- "lbl" : "cellular blastoderm stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005311",
- "meta" : {
- "definition" : {
- "val" : "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).",
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- "comments" : [ "Temporal ordering number - 210." ],
- "synonyms" : [ {
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- "type" : "CLASS",
- "lbl" : "embryonic stage 5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0009790",
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- "definition" : {
- "val" : "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.",
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- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate" ],
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- "val" : "Wikipedia:Embryogenesis"
- } ],
- "synonyms" : [ {
- "pred" : "hasBroadSynonym",
- "val" : "embryogenesis and morphogenesis",
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- }, {
- "pred" : "hasExactSynonym",
- "val" : "embryogenesis",
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- "pred" : "hasExactSynonym",
- "val" : "embryonal development",
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- "val" : "biological_process"
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- "val" : "GO:0009795"
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- },
- "type" : "CLASS",
- "lbl" : "embryo development"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005303",
- "meta" : {
- "definition" : {
- "val" : "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- },
- "comments" : [ "Temporal ordering number - 180." ],
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- "lbl" : "embryonic cycle 10"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005304",
- "meta" : {
- "definition" : {
- "val" : "Embryonic stages 4 and 5.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 160." ],
- "synonyms" : [ {
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- "val" : "blastoderm",
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- "lbl" : "blastoderm stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005301",
- "meta" : {
- "definition" : {
- "val" : "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 140." ],
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- "type" : "CLASS",
- "lbl" : "embryonic stage 3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005302",
- "meta" : {
- "definition" : {
- "val" : "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- },
- "comments" : [ "Temporal ordering number - 150." ],
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 9"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005307",
- "meta" : {
- "definition" : {
- "val" : "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 185." ],
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- "lbl" : "embryonic cycle 11"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005308",
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- "definition" : {
- "val" : "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- },
- "comments" : [ "Temporal ordering number - 190." ],
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 12"
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- "type" : "CLASS",
- "lbl" : "syncytial blastoderm stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005306",
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- "definition" : {
- "val" : "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).",
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- "comments" : [ "Temporal ordering number - 170." ],
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- "val" : "syncytial blastoderm stage",
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- "pred" : "hasExactSynonym",
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- "lbl" : "embryonic stage 4"
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- "lbl" : "has_related_synonym"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005309",
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- "definition" : {
- "val" : "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- "comments" : [ "Temporal ordering number - 200." ],
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 13"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007081",
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- "definition" : {
- "val" : "6th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
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- "comments" : [ "Temporal ordering number - 860." ],
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- "type" : "CLASS",
- "lbl" : "day 6 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007080",
- "meta" : {
- "definition" : {
- "val" : "5th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 850." ],
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- "lbl" : "day 5 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007085",
- "meta" : {
- "definition" : {
- "val" : "10th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 900." ],
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- "type" : "CLASS",
- "lbl" : "day 10 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007084",
- "meta" : {
- "definition" : {
- "val" : "9th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 890." ],
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- "type" : "CLASS",
- "lbl" : "day 9 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007083",
- "meta" : {
- "definition" : {
- "val" : "8th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 880." ],
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- "type" : "CLASS",
- "lbl" : "day 8 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007082",
- "meta" : {
- "definition" : {
- "val" : "7th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 870." ],
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- "type" : "CLASS",
- "lbl" : "day 7 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007089",
- "meta" : {
- "definition" : {
- "val" : "14th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
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- "comments" : [ "Temporal ordering number - 940." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "day 14 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005340",
- "meta" : {
- "definition" : {
- "val" : "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).",
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- "comments" : [ "Temporal ordering number - 440." ],
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- "val" : "2008-11-13T11:51:56Z"
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- "type" : "CLASS",
- "lbl" : "early third instar larval stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007088",
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- "val" : "13th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 930." ],
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- "comments" : [ "Temporal ordering number - 920." ],
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- "type" : "CLASS",
- "lbl" : "day 12 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007086",
- "meta" : {
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- "val" : "11th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 910." ],
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- "val" : "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 510." ],
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- "lbl" : "prepupal stage P1"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005344",
- "meta" : {
- "definition" : {
- "val" : "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 520." ],
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- "val" : "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.",
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- "comments" : [ "Temporal ordering number - 460." ],
- "synonyms" : [ {
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- "val" : "2008-11-13T11:55:46Z"
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- "lbl" : "wandering third instar larval stage"
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- "val" : "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 500." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005336",
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- "val" : "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.",
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- "comments" : [ "Temporal ordering number - 400." ],
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- "val" : "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).",
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- "comments" : [ "Temporal ordering number - 410." ],
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- "comments" : [ "Temporal ordering number - 380." ],
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- "comments" : [ "Temporal ordering number - 390." ],
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- "val" : "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).",
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- "comments" : [ "Temporal ordering number - 420." ],
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- "val" : "L2",
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- "val" : "The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).",
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- "comments" : [ "Temporal ordering number - 430." ],
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- "val" : "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.",
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007078",
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- "val" : "3rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
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- "comments" : [ "Temporal ordering number - 830." ],
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- "definition" : {
- "val" : "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y",
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- "val" : "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.",
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- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has developmental potential involving"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002263",
- "meta" : {
- "definition" : {
- "val" : "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.",
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- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision."
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007079",
- "meta" : {
- "definition" : {
- "val" : "4th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 840." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 4 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005331",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 13-15.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 330." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "dorsal closure stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005325",
- "meta" : {
- "definition" : {
- "val" : "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 310." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 11"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005326",
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- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "contracted germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005323",
- "meta" : {
- "definition" : {
- "val" : "Stage 9 begins when mesodermal segmentation becomes (transiently) visible\\, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 280." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
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- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005324",
- "meta" : {
- "definition" : {
- "val" : "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 290." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
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- "type" : "CLASS",
- "lbl" : "embryonic stage 10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005329",
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- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "head involution stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002015",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.",
- "xrefs" : [ ]
- },
- "comments" : [ "By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'." ],
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- "val" : "2017-05-24T09:31:17Z"
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- "val" : "dos"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has positive regulatory component activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002258",
- "meta" : {
- "definition" : {
- "val" : "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p",
- "xrefs" : [ ]
- },
- "comments" : [ "This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from" ],
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "false"
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- "val" : "In general you should not use this relation to make assertions - use one of the more specific relations below this one"
- }, {
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- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
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- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "developmentally preceded by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005327",
- "meta" : {
- "definition" : {
- "val" : "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 320." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "retracting germ band stage",
- "xrefs" : [ ]
- } ],
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- "lbl" : "embryonic stage 12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002017",
- "meta" : {
- "comments" : [ "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ],
- "basicPropertyValues" : [ {
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2017-05-24T09:44:33Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has component activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002018",
- "meta" : {
- "definition" : {
- "val" : "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
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- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has component process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005328",
- "meta" : {
- "definition" : {
- "val" : "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 340." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "contracted germ band stage",
- "xrefs" : [ ]
- } ],
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- } ]
- },
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- "lbl" : "embryonic stage 13"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "type" : "PROPERTY",
- "lbl" : "has_alternative_id"
- }, {
- "id" : "http://purl.obolibrary.org/obo/CARO_0000000",
- "meta" : {
- "basicPropertyValues" : [ {
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "anatomical entity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0098763",
- "meta" : {
- "definition" : {
- "val" : "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.",
- "xrefs" : [ "GOC:dos" ]
- },
- "comments" : [ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ],
- "basicPropertyValues" : [ {
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- "val" : "biological_process"
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- },
- "type" : "CLASS",
- "lbl" : "mitotic cell cycle phase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0011002",
- "meta" : {
- "definition" : {
- "val" : "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007023",
- "meta" : {
- "definition" : {
- "val" : "The M-phase (GO:0000279) of an embryonic cycle.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle M-phase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002254",
- "meta" : {
- "definition" : {
- "val" : "x has developmental contribution from y iff x has some part z such that z develops from y",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
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- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has developmental contribution from"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002012",
- "meta" : {
- "definition" : {
- "val" : "A part of relation that applies only between occurents.",
- "xrefs" : [ ]
- },
- "xrefs" : [ {
- "val" : "RO:0002012"
- } ],
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- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "occurent part of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007022",
- "meta" : {
- "definition" : {
- "val" : "The interphase (GO:0051325) of an embryonic cycle.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle interphase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002013",
- "meta" : {
- "definition" : {
- "val" : "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
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- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has regulatory component activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002255",
- "meta" : {
- "definition" : {
- "val" : "inverse of has developmental contribution from",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
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- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "developmentally contributes to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007021",
- "meta" : {
- "definition" : {
- "val" : "The substage of the wandering third instar larval stage when the larva has cleared its gut contents.",
- "xrefs" : [ "FlyBase:FBrf0076598" ]
- },
- "comments" : [ "Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994." ],
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- },
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- "lbl" : "third instar - cleared gut stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007020",
- "meta" : {
- "definition" : {
- "val" : "The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.",
- "xrefs" : [ "FlyBase:FBrf0076598" ]
- },
- "comments" : [ "Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994)." ],
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- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002014",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.",
- "xrefs" : [ ]
- },
- "comments" : [ "By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'." ],
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- },
- "type" : "PROPERTY",
- "lbl" : "has negative regulatory component activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007026",
- "meta" : {
- "definition" : {
- "val" : "Life stage from the end of adult stage A3, when tanning is complete, to death.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "mature adult stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007025",
- "meta" : {
- "definition" : {
- "val" : "The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 782." ],
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- "meta" : {
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- "val" : "The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.",
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- },
- "comments" : [ "Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994)." ],
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- "lbl" : "third instar - uncleared gut stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007018",
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- "val" : "Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
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- "comments" : [ "Temporal ordering number - 394. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
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- "val" : "Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).",
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- "comments" : [ "Temporal ordering number - 393. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
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- "val" : "karyostasis",
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- "definition" : {
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- "val" : "58th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
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- "comments" : [ "Temporal ordering number - 1380." ],
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- "val" : "A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.",
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- "val" : "57th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
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- "comments" : [ "Temporal ordering number - 1370." ],
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- "val" : "A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.",
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- "meta" : {
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- "val" : "55th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
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- "val" : "Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
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- "val" : "The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007128",
- "meta" : {
- "definition" : {
- "val" : "53rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1330." ],
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 53 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007007",
- "meta" : {
- "definition" : {
- "val" : "Third instar larva from the beginning of wandering to the beginning of puparium formation.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 450." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-12-11T01:19:53Z"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "late third instar larval stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007006",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).",
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- },
- "comments" : [ "Temporal ordering number - 10250." ],
- "basicPropertyValues" : [ {
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- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13E"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0000057",
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- "definition" : {
- "val" : "a relation between a process and a continuant, in which the continuant is somehow involved in the process",
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- },
- "basicPropertyValues" : [ {
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- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this blood coagulation has participant this blood clot"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "has_participant"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "has participant"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has participant"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007127",
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- "definition" : {
- "val" : "52nd day after eclosion.",
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- },
- "comments" : [ "Temporal ordering number - 1320." ],
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- "type" : "CLASS",
- "lbl" : "day 52 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/RO_0002598",
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- "definition" : {
- "val" : "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.",
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- },
- "basicPropertyValues" : [ {
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "renin -> arteriolar smooth muscle contraction"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "capable of positively regulating"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0045448",
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- "definition" : {
- "val" : "The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.",
- "xrefs" : [ "GOC:go_curators" ]
- },
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- },
- "type" : "CLASS",
- "lbl" : "mitotic cell cycle, embryonic"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002479",
- "meta" : {
- "definition" : {
- "val" : "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
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- },
- "type" : "PROPERTY",
- "lbl" : "has part that occurs in"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0009987",
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- "xrefs" : [ "GOC:go_curators", "GOC:isa_complete" ]
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- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_plant" ],
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- "pred" : "hasExactSynonym",
- "val" : "cellular physiological process",
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- }, {
- "pred" : "hasExactSynonym",
- "val" : "cell physiology",
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- }, {
- "pred" : "hasNarrowSynonym",
- "val" : "cell growth and/or maintenance",
- "xrefs" : [ ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "single-organism cellular process",
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- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- }, {
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- "val" : "GO:0044763"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "GO:0008151"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "GO:0050875"
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- },
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- },
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- "val" : "inverse of has input",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/RO_0002259" ],
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- },
- "type" : "PROPERTY",
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- } ]
- },
- "type" : "PROPERTY",
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- },
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- },
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- },
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- },
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- },
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- "comments" : [ "Temporal ordering number - 130." ],
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- }, {
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- "meta" : {
- "comments" : [ "This should be considered as a type of cell rather than as a stage. Please use FBbt:00005412." ],
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- }, {
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- },
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- } ]
- },
- "type" : "PROPERTY",
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- "definition" : {
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- } ]
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- "definition" : {
- "val" : "The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355", "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 625." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005282",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10240." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13D"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002211",
- "meta" : {
- "definition" : {
- "val" : "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Regulation precludes parthood; the regulatory process may not be within the regulated process."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "GO"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Hill"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000600",
- "val" : "false"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Tanya Berardini"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "regulates (processual)"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "regulates"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002212",
- "meta" : {
- "definition" : {
- "val" : "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "negatively regulates (process to process)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
- "val" : "http://purl.obolibrary.org/obo/RO_0002211"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "negatively regulates"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002333",
- "meta" : {
- "definition" : {
- "val" : "inverse of enables",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "enabled by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005283",
- "meta" : {
- "definition" : {
- "val" : "The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10260." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005288",
- "meta" : {
- "comments" : [ "Temporal ordering number - 10." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "fertilized egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007104",
- "meta" : {
- "definition" : {
- "val" : "29th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1090." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 29 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005289",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from fertilization to hatching.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 20." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007103",
- "meta" : {
- "definition" : {
- "val" : "28th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1080." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 28 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007102",
- "meta" : {
- "definition" : {
- "val" : "27th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1070." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 27 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00006012",
- "meta" : {
- "definition" : {
- "val" : "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 800." ],
- "synonyms" : [ {
- "pred" : "hasRelatedSynonym",
- "val" : "adult stage III",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "FBdv:00005375"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "adult stage A3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005286",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.",
- "xrefs" : [ "FlyBase:FBrf0064779" ]
- },
- "comments" : [ "Temporal ordering number - 10290." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002450",
- "meta" : {
- "definition" : {
- "val" : "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.",
- "xrefs" : [ ]
- },
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "molecularly increases activity of",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "directly activates"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "directly positively regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005287",
- "meta" : {
- "comments" : [ "Temporal ordering number - 10300." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "unfertilized egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007101",
- "meta" : {
- "definition" : {
- "val" : "26th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1060." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 26 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002448",
- "meta" : {
- "definition" : {
- "val" : "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.",
- "xrefs" : [ ]
- },
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "molecularly controls",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "directly regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002327",
- "meta" : {
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "executes"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "catalyzes"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "a particular instances of akt-2 enables some instance of protein kinase activity"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "is catalyzing"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "is executing"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "has"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "enables"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002449",
- "meta" : {
- "definition" : {
- "val" : "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.",
- "xrefs" : [ ]
- },
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "molecularly decreases activity of",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "directly inhibits"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "directly negatively regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002328",
- "meta" : {
- "definition" : {
- "val" : "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "This is a grouping relation that collects relations used for the purpose of connecting structure and function"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "functionally related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002329",
- "meta" : {
- "definition" : {
- "val" : "this relation holds between c and p when c is part of some c', and c' is capable of p.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "false"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "part of structure that is capable of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005279",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000050",
- "meta" : {
- "definition" : {
- "val" : "a core relation that holds between a part and its whole",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
- "xrefs" : [ {
- "val" : "BFO:0000050"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "part_of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000004"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000003"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000002"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://www.obofoundry.org/ro/#OBO_REL:part_of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my brain is part of my body (continuant parthood, two material entities)"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000020"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000017"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000019"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "is part of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this day is part of this year (occurrent parthood)"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://ontologydesignpatterns.org/wiki/Submissions:PartOf"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000031"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "part_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "part of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002323",
- "meta" : {
- "definition" : {
- "val" : "A mereological relationship or a topological relationship",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "mereotopologically related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002202",
- "meta" : {
- "definition" : {
- "val" : "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y",
- "xrefs" : [ ]
- },
- "comments" : [ "This is the transitive form of the develops from relation" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Terry Meehan"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Melissa Haendel"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "develops from"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002203",
- "meta" : {
- "definition" : {
- "val" : "inverse of develops from",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Terry Meehan"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "develops into"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002566",
- "meta" : {
- "definition" : {
- "val" : "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "causally influences (entity-centric)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "causally influences"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002324",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between entities participating in some developmental process (GO:0032502)",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "developmentally related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002447",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Axiomatization to GO to be added later"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y."
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "phosphorylates"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00018001",
- "meta" : {
- "comments" : [ "Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO." ],
- "xrefs" : [ {
- "val" : "FBdv:00018001"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "substage_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "substage_of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/IAO_0000115",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "definition"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000051",
- "meta" : {
- "definition" : {
- "val" : "a core relation that holds between a whole and its part",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
- "xrefs" : [ {
- "val" : "OBO_REL:has_part"
- }, {
- "val" : "BFO:0000051"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "has_part"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "has_part"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "has part"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this year has part this day (occurrent parthood)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my body has part my brain (continuant parthood, two material entities)"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has_part"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005270",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10100." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005273",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0043885", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10130." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005274",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0043885", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10160." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005271",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074" ]
- },
- "comments" : [ "Temporal ordering number - 10110." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002563",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://xmlns.com/foaf/0.1/page",
- "val" : "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "interaction relation helper property"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002564",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "molecular interaction relation helper property"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005272",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10120." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005277",
- "meta" : {
- "definition" : {
- "val" : "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.",
- "xrefs" : [ "FlyBase:FBrf0021038" ]
- },
- "comments" : [ "Temporal ordering number - 10190." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12C"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005278",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0029744", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10200." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005275",
- "meta" : {
- "definition" : {
- "val" : "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10170." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005276",
- "meta" : {
- "definition" : {
- "val" : "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10180." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002559",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "causally influenced by (entity-centric)"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "causally influenced by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005268",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10080." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005269",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10090." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002434",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between two entities in which the processes executed by the two entities are causally connected.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "in pairwise interaction with",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://purl.obolibrary.org/obo/MI_0914"
- }, {
- "pred" : "http://xmlns.com/foaf/0.1/page",
- "val" : "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Considering relabeling as 'pairwise interacts with'"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "interacts with"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002314",
- "meta" : {
- "definition" : {
- "val" : "q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "https://github.com/oborel/obo-relations/wiki/ROGuide#defining-property-chains-involving-reflexivity"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Because part_of is transitive, inheres in is a sub-relation of inheres in part of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "inheres in part of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002436",
- "meta" : {
- "definition" : {
- "val" : "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "molecularly binds with"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "binds"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://purl.obolibrary.org/obo/ECO_0000353"
- }, {
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- "val" : "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t",
- "xrefs" : [ ]
- },
- "comments" : [ "Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant" ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
- "val" : "http://purl.obolibrary.org/obo/bfo.owl"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "site of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "contains process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000062",
- "meta" : {
- "definition" : {
- "val" : "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
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- "val" : "OBO_REL:preceded_by"
- }, {
- "val" : "BFO:0000062"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.org/dc/elements/1.1/source",
- "val" : "http://www.obofoundry.org/ro/#OBO_REL:preceded_by"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "is preceded by"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "preceded by"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "preceded_by"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "preceded_by"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "preceded_by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0003824",
- "type" : "CLASS",
- "lbl" : "catalytic activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000063",
- "meta" : {
- "definition" : {
- "val" : "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
- "xrefs" : [ ]
- },
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- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "precedes"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "precedes"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002091",
- "meta" : {
- "comments" : [ "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "io"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "starts during"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule",
- "type" : "PROPERTY",
- "lbl" : "namespace-id-rule"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002092",
- "meta" : {
- "comments" : [ "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
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- "val" : "RO:0002092"
- } ],
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- "val" : "happens_during"
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- "val" : "during"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "d"
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- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "happens during"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002093",
- "meta" : {
- "comments" : [ "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). " ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "xrefs" : [ {
- "val" : "RO:0002093"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "ends_during"
- }, {
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- "val" : "o"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "overlaps"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "ends during"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0000087",
- "meta" : {
- "definition" : {
- "val" : "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.",
- "xrefs" : [ "GOC:mtg_cell_cycle" ]
- },
- "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "M phase of mitotic cell cycle",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "M-phase of mitotic cell cycle",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "mitotic M phase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000015",
- "meta" : {
- "definition" : {
- "val" : "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.",
- "xrefs" : [ ]
- }
- },
- "type" : "CLASS",
- "lbl" : "process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002090",
- "meta" : {
- "comments" : [ "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "xrefs" : [ {
- "val" : "RO:0002090"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "ends_at_start_of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "meets"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0002575",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000063"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "ends_at_start_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "ends_at_start_of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005361",
- "meta" : {
- "definition" : {
- "val" : "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 690." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004035",
- "meta" : {
- "definition" : {
- "val" : "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2018-01-26T23:53:22Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "cjm"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
- "val" : "http://purl.obolibrary.org/obo/RO_0002263"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of,_negative_effect"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of, negative effect"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005362",
- "meta" : {
- "definition" : {
- "val" : "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 700." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "wing tips grey stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12(i)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P12(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002410",
- "meta" : {
- "definition" : {
- "val" : "This relation groups causal relations between material entities and causal relations between processes",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types."
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "causally related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005360",
- "meta" : {
- "definition" : {
- "val" : "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 680." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "thoracic bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11(ii)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005365",
- "meta" : {
- "definition" : {
- "val" : "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 730." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P14",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "mature bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004032",
- "meta" : {
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "cjm"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
- "val" : "http://purl.obolibrary.org/obo/RO_0002264"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2018-01-26T23:49:30Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of or within, positive effect"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0007275",
- "meta" : {
- "definition" : {
- "val" : "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",
- "xrefs" : [ "GOC:dph", "GOC:ems", "GOC:isa_complete", "GOC:tb" ]
- },
- "comments" : [ "Note that this term was 'developmental process'." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_plant" ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "multicellular organism development"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005366",
- "meta" : {
- "definition" : {
- "val" : "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 740." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P15",
- "xrefs" : [ ]
- } ],
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004031",
- "meta" : {
- "definition" : {
- "val" : "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2018-01-25T23:20:13Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "cjm"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "enables subfunction"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004034",
- "meta" : {
- "definition" : {
- "val" : "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
- "val" : "http://purl.obolibrary.org/obo/RO_0002263"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "cjm"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of,_positive_effect"
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- "val" : "2018-01-26T23:53:14Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of, positive effect"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005363",
- "meta" : {
- "definition" : {
- "val" : "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 710." ],
- "synonyms" : [ {
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- "val" : "pupal stage P12(ii)",
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- }, {
- "pred" : "hasExactSynonym",
- "val" : "wings grey stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
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- "lbl" : "pharate adult stage P12(ii)"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005364",
- "meta" : {
- "definition" : {
- "val" : "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 720." ],
- "synonyms" : [ {
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- "val" : "pupal stage P13",
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- }, {
- "pred" : "hasExactSynonym",
- "val" : "wings black stage",
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- "lbl" : "pharate adult stage P13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004033",
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- "val" : "cjm"
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- "val" : "2018-01-26T23:49:51Z"
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- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of or within, negative effect"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002404",
- "meta" : {
- "definition" : {
- "val" : "inverse of upstream of",
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- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
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- "val" : "Chris Mungall"
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- },
- "type" : "PROPERTY",
- "lbl" : "causally downstream of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005358",
- "meta" : {
- "definition" : {
- "val" : "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 660." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005359",
- "meta" : {
- "definition" : {
- "val" : "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 670." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11(i)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "head bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002405",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "immediately causally downstream of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005356",
- "meta" : {
- "definition" : {
- "val" : "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 640." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "amber-eyed stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P9",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005357",
- "meta" : {
- "definition" : {
- "val" : "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 650." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P10",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "red-eye bald stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0016301",
- "type" : "CLASS",
- "lbl" : "kinase activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_root_00000000",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0100001",
- "val" : "http://purl.obolibrary.org/obo/FBdv_00000000"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000231",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000227"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007092",
- "meta" : {
- "definition" : {
- "val" : "17th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 970." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 17 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007091",
- "meta" : {
- "definition" : {
- "val" : "16th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 960." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 16 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007090",
- "meta" : {
- "definition" : {
- "val" : "15th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 950." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 15 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007096",
- "meta" : {
- "definition" : {
- "val" : "21st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1010." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 21 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000004",
- "meta" : {
- "definition" : {
- "val" : "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.",
- "xrefs" : [ ]
- }
- },
- "type" : "CLASS",
- "lbl" : "independent continuant"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007095",
- "meta" : {
- "definition" : {
- "val" : "20th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1000." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 20 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007094",
- "meta" : {
- "definition" : {
- "val" : "19th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 990." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 19 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0006996",
- "meta" : {
- "definition" : {
- "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.",
- "xrefs" : [ "GOC:mah" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_aspergillus" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "single organism organelle organization",
- "xrefs" : [ "GOC:TermGenie" ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "organelle organization and biogenesis",
- "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:mah" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "organelle organisation",
- "xrefs" : [ ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "single-organism organelle organization",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "GO:1902589"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "jl"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2013-12-19T15:25:51Z"
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- },
- "type" : "CLASS",
- "lbl" : "organelle organization"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007093",
- "meta" : {
- "definition" : {
- "val" : "18th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 980." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 18 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0007049",
- "meta" : {
- "definition" : {
- "val" : "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.",
- "xrefs" : [ "GOC:go_curators", "GOC:mtg_cell_cycle" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_aspergillus", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl" ],
- "xrefs" : [ {
- "val" : "Wikipedia:Cell_cycle"
- } ],
- "synonyms" : [ {
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- "val" : "cell-division cycle",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
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- "type" : "CLASS",
- "lbl" : "cell cycle"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005350",
- "meta" : {
- "definition" : {
- "val" : "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 580." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
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- "type" : "CLASS",
- "lbl" : "pupal stage P5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002088",
- "meta" : {
- "comments" : [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
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- "val" : "David Osumi-Sutherland"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "during which starts"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005351",
- "meta" : {
- "definition" : {
- "val" : "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 590." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "Malpighian tubules migrating",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
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- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007099",
- "meta" : {
- "definition" : {
- "val" : "24th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1040." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 24 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007098",
- "meta" : {
- "definition" : {
- "val" : "23rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1030." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 23 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007097",
- "meta" : {
- "definition" : {
- "val" : "22nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1020." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 22 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002084",
- "meta" : {
- "comments" : [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "during which ends"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005354",
- "meta" : {
- "definition" : {
- "val" : "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 620." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "yellow body stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002085",
- "meta" : {
- "comments" : [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ],
- "basicPropertyValues" : [ {
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- "val" : "David Osumi-Sutherland"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "di"
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- },
- "type" : "PROPERTY",
- "lbl" : "encompasses"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005355",
- "meta" : {
- "definition" : {
- "val" : "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 630." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "yellow-eyed stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P8",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005352",
- "meta" : {
- "definition" : {
- "val" : "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 600." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "white Malpighian tubules stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002086",
- "meta" : {
- "comments" : [ "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- } ]
- },
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- "lbl" : "ends after"
- }, {
- "id" : "http://purl.obolibrary.org/obo/fbdv#systematic_synonym",
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- "basicPropertyValues" : [ {
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- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "Systematic synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002087",
- "meta" : {
- "comments" : [ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" ],
- "xrefs" : [ {
- "val" : "RO:0002087"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "immediately_preceded_by"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "starts_at_end_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "immediately_preceded_by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005353",
- "meta" : {
- "definition" : {
- "val" : "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 610." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "green Malpighian tubules stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P6"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005347",
- "meta" : {
- "definition" : {
- "val" : "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 550." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P4(i)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "buoyant stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P4(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005348",
- "meta" : {
- "definition" : {
- "val" : "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 560." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "moving bubble stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P4(ii)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P4(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005345",
- "meta" : {
- "definition" : {
- "val" : "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 530." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "bubble prepupa stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P3",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005346",
- "meta" : {
- "definition" : {
- "val" : "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 540." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "cryptocephalic pupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P4",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P4"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0140014",
- "meta" : {
- "definition" : {
- "val" : "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",
- "xrefs" : [ "ISBN:0198547684" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "mitosis",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000233",
- "val" : "https://github.com/geneontology/go-ontology/issues/19910"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2017-03-23T14:44:23Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "pg"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "mitotic nuclear division"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005349",
- "meta" : {
- "definition" : {
- "val" : "The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 570. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for Cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head and expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "phanerocephalic pupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym",
- "type" : "PROPERTY",
- "lbl" : "has_broad_synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000002",
- "meta" : {
- "definition" : {
- "val" : "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.",
- "xrefs" : [ ]
+ ],
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00000000"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00005259"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00007013"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00007024"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/creator",
+ "val": "http://orcid.org/0000-0002-1373-1705"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/creator",
+ "val": "http://orcid.org/0000-0002-7073-9172"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/creator",
+ "val": "https://orcid.org/0000-0001-5948-3092"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/creator",
+ "val": "https://orcid.org/0000-0002-0027-0858"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/description",
+ "val": "An ontology of Drosophila melanogaster developmental stages."
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/title",
+ "val": "FlyBase Developmental Ontology (FBdv)"
+ },
+ {
+ "pred": "http://purl.org/dc/terms/license",
+ "val": "https://creativecommons.org/licenses/by/3.0/"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule",
+ "val": "* FBdv:$sequence(8,7000,10000)$"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#date",
+ "val": "10:03:2021 10:38"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#default-namespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion",
+ "val": "1.2"
+ },
+ {
+ "pred": "http://www.w3.org/2002/07/owl#versionInfo",
+ "val": "2021-03-10"
+ }
+ ],
+ "subsets": [],
+ "version": "http://purl.obolibrary.org/obo/fbdv/releases/2021-03-10/fbdv-full.json",
+ "xrefs": []
+ },
+ "nodes": [
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000002",
+ "lbl": "continuant",
+ "meta": {
+ "definition": {
+ "val": "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000003",
+ "lbl": "occurrent",
+ "meta": {
+ "definition": {
+ "val": "An entity that has temporal parts and that happens, unfolds or develops through time.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000004",
+ "lbl": "independent continuant",
+ "meta": {
+ "definition": {
+ "val": "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000015",
+ "lbl": "process",
+ "meta": {
+ "definition": {
+ "val": "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000020",
+ "lbl": "specifically dependent continuant",
+ "meta": {
+ "definition": {
+ "val": "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000040",
+ "lbl": "material entity",
+ "meta": {
+ "definition": {
+ "val": "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000050",
+ "lbl": "part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "is part of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my brain is part of my body (continuant parthood, two material entities)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this day is part of this year (occurrent parthood)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "part_of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000002"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000003"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000004"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000017"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000019"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000020"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000031"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "part_of"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Submissions:PartOf"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://www.obofoundry.org/ro/#OBO_REL:part_of"
+ }
+ ],
+ "definition": {
+ "val": "a core relation that holds between a part and its whole",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000050"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000051",
+ "lbl": "has_part",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "has part"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my body has part my brain (continuant parthood, two material entities)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this year has part this day (occurrent parthood)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has_part"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "has_part"
+ }
+ ],
+ "definition": {
+ "val": "a core relation that holds between a whole and its part",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000051"
+ },
+ {
+ "val": "OBO_REL:has_part"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000062",
+ "lbl": "preceded_by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "preceded by"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "is preceded by"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "preceded_by"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/source",
+ "val": "http://www.obofoundry.org/ro/#OBO_REL:preceded_by"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "preceded_by"
+ }
+ ],
+ "definition": {
+ "val": "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000062"
+ },
+ {
+ "val": "OBO_REL:preceded_by"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000063",
+ "lbl": "precedes",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "precedes"
+ }
+ ],
+ "definition": {
+ "val": "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000066",
+ "lbl": "occurs in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "occurs in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "occurs_in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "unfolds in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "unfolds_in"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
+ "val": "http://purl.obolibrary.org/obo/bfo.owl"
+ }
+ ],
+ "comments": [
+ "Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant"
+ ],
+ "definition": {
+ "val": "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000067",
+ "lbl": "contains process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "site of"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
+ "val": "http://purl.obolibrary.org/obo/bfo.owl"
+ }
+ ],
+ "comments": [
+ "Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant"
+ ],
+ "definition": {
+ "val": "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/CARO_0000000",
+ "lbl": "anatomical entity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000412",
+ "val": "http://purl.obolibrary.org/obo/caro.owl"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00000000",
+ "lbl": "Drosophila life",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv_root:00000000"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The life of an individual of the species Drosophila melanogaster, from fertilization to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "Drosophila life cycle",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00000054",
+ "lbl": "cleavage stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 25."
+ ],
+ "definition": {
+ "val": "A collective term for stages 1-4.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00004450",
+ "lbl": "late extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 300."
+ ],
+ "definition": {
+ "val": "A collective term for stages 11 and 12.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00004886",
+ "lbl": "oogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10000."
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "oogenesis stage",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0048477"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005259",
+ "lbl": "developmental stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:56:56Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00007010"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A temporal subdivision of a developmental process.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005261",
+ "lbl": "oogenesis stage S1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10010."
+ ],
+ "definition": {
+ "val": "Earliest stage of ovarian cyst development - lasts while the 16 cell cyst is within the germarium (region 3).",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005262",
+ "lbl": "oogenesis stage S2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10020."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the cyst leaves the germarium (from this point the cyst is referred to as an egg chamber). During this stage, polyploidation of the nurse cells begins, they reach a ploidy of 8C, and follicle cells start to divide.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005263",
+ "lbl": "oogenesis stage S3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10030."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the oocyte chromosomes condense into a karyosome attached to a distinctive spherical structure known as an endobody. The oocyte nucleolus disappears completely. During this stage, nurse cell ploidy reaches 16C.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005264",
+ "lbl": "oogenesis stage S4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10040."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the nurse cells chromosomes become bulbous. Nurse cell chromosomes during this stage are polytene and reach a ploidy of 32C. The egg chamber is oval shaped.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005265",
+ "lbl": "oogenesis stage S5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10050."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell chromosomes are no longer bulbous - the association between homologs weakens so that these chromosomes no longer have a polytene structure. During this stage, posterior nurse cell nuclei have a higher ploidy (64C) than anterior ones.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005266",
+ "lbl": "oogenesis stage S6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10060."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which follicle cell division ceases.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005267",
+ "lbl": "oogenesis stage S7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10070."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which polyploidation and enlargement of follicle cells begins. Nurse cell ploidy ranges from 256C (anterior) to 512C (posterior) and the egg chamber gains an elongated shape.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005268",
+ "lbl": "oogenesis stage S8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10080."
+ ],
+ "definition": {
+ "val": "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005269",
+ "lbl": "oogenesis stage S9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10090."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005270",
+ "lbl": "oogenesis stage S10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10100."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005271",
+ "lbl": "oogenesis stage S10A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10110."
+ ],
+ "definition": {
+ "val": "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005272",
+ "lbl": "oogenesis stage S10B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10120."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005273",
+ "lbl": "oogenesis stage S11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10130."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0043885",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005274",
+ "lbl": "oogenesis stage S12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10160."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0043885",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005275",
+ "lbl": "oogenesis stage S12A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10170."
+ ],
+ "definition": {
+ "val": "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005276",
+ "lbl": "oogenesis stage S12B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10180."
+ ],
+ "definition": {
+ "val": "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005277",
+ "lbl": "oogenesis stage S12C",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10190."
+ ],
+ "definition": {
+ "val": "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.",
+ "xrefs": [
+ "FlyBase:FBrf0021038"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005278",
+ "lbl": "oogenesis stage S13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10200."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0029744",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005279",
+ "lbl": "oogenesis stage S13A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005280",
+ "lbl": "oogenesis stage S13B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10220. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which 9-11 nurse cell nuclei remain at the anterior of the oocyte. During this stage, the nuclear membrane of the oocyte nucleus disappears, indicating the start of meiotic pro-metaphase.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005281",
+ "lbl": "oogenesis stage S13C",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10230."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which only 7-8 nurse cell nuclei remain at the anterior of the oocyte. At the beginning of this stage, oocyte chromosome bivalents separate from each other - indicating mid-prometaphase of oocyte meiosis.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005282",
+ "lbl": "oogenesis stage S13D",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10240."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005283",
+ "lbl": "oogenesis stage S14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10260."
+ ],
+ "definition": {
+ "val": "The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005284",
+ "lbl": "oogenesis stage S14A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10270."
+ ],
+ "definition": {
+ "val": "Secretion and formation of the outer endochorionic network by throughout the follicle. Crystallization of the innermost chorionic layer of the main body follicle cells.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005285",
+ "lbl": "oogenesis stage S14B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10280."
+ ],
+ "definition": {
+ "val": "Secretion of the exochorion begins and ends.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005286",
+ "lbl": "egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10290."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.",
+ "xrefs": [
+ "FlyBase:FBrf0064779"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005287",
+ "lbl": "unfertilized egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10300."
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005288",
+ "lbl": "fertilized egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10."
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005289",
+ "lbl": "embryonic stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 20."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from fertilization to hatching.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005290",
+ "lbl": "pre-blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 30."
+ ],
+ "definition": {
+ "val": "Embryonic stage 1-3.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pre-blastoderm",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005291",
+ "lbl": "embryonic stage 1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 40."
+ ],
+ "definition": {
+ "val": "The embryonic stage that lasts from the end of fertilization to the end of the second nuclear division. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0064779",
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005292",
+ "lbl": "embryonic cycle 1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 50."
+ ],
+ "definition": {
+ "val": "The first mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005293",
+ "lbl": "embryonic stage 2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 70."
+ ],
+ "definition": {
+ "val": "Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005294",
+ "lbl": "embryonic cycle 2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 60."
+ ],
+ "definition": {
+ "val": "The second mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005295",
+ "lbl": "embryonic cycle 3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 80."
+ ],
+ "definition": {
+ "val": "The third mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005296",
+ "lbl": "embryonic cycle 4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 90."
+ ],
+ "definition": {
+ "val": "The fourth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005297",
+ "lbl": "embryonic cycle 5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 100."
+ ],
+ "definition": {
+ "val": "The fifth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005298",
+ "lbl": "embryonic cycle 6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 110."
+ ],
+ "definition": {
+ "val": "The sixth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005299",
+ "lbl": "embryonic cycle 7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 120."
+ ],
+ "definition": {
+ "val": "The seventh mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005300",
+ "lbl": "embryonic cycle 8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 130."
+ ],
+ "definition": {
+ "val": "The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005301",
+ "lbl": "embryonic stage 3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 140."
+ ],
+ "definition": {
+ "val": "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005302",
+ "lbl": "embryonic cycle 9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 150."
+ ],
+ "definition": {
+ "val": "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005303",
+ "lbl": "embryonic cycle 10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 180."
+ ],
+ "definition": {
+ "val": "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005304",
+ "lbl": "blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 160."
+ ],
+ "definition": {
+ "val": "Embryonic stages 4 and 5.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "blastoderm",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005305",
+ "lbl": "syncytial blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005306",
+ "lbl": "embryonic stage 4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 170."
+ ],
+ "definition": {
+ "val": "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "syncytial blastoderm",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "syncytial blastoderm stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005307",
+ "lbl": "embryonic cycle 11",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 185."
+ ],
+ "definition": {
+ "val": "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005308",
+ "lbl": "embryonic cycle 12",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 190."
+ ],
+ "definition": {
+ "val": "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005309",
+ "lbl": "embryonic cycle 13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 200."
+ ],
+ "definition": {
+ "val": "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005310",
+ "lbl": "cellular blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005311",
+ "lbl": "embryonic stage 5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 210."
+ ],
+ "definition": {
+ "val": "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular blastoderm",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular blastoderm stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005312",
+ "lbl": "embryonic cycle 14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "FlyBase:FBrf0049535",
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "first blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005313",
+ "lbl": "embryonic cycle 14A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 256."
+ ],
+ "definition": {
+ "val": "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "[FlyBase:FBrf0039741"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonic cycle 14 interphase",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005314",
+ "lbl": "embryonic cycle 14B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "FlyBase:FBrf0039741"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonic cycle 14 M-phase",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005315",
+ "lbl": "embryonic cycle 15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 15th cell cycle of embryogenesis. Asynchronous.",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "second blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005316",
+ "lbl": "embryonic cycle 16",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 16th cell cycle division of embryogenesis. Asynchronous.",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "third blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005317",
+ "lbl": "gastrula stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 220."
+ ],
+ "definition": {
+ "val": "Stages during which gastrulation occurs. 6-8.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "gastrula",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005318",
+ "lbl": "embryonic stage 6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 230."
+ ],
+ "definition": {
+ "val": "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005319",
+ "lbl": "embryonic stage 7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 240."
+ ],
+ "definition": {
+ "val": "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005320",
+ "lbl": "germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005321",
+ "lbl": "extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 260."
+ ],
+ "definition": {
+ "val": "Stages during which the germ band is extended - 9-12.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005322",
+ "lbl": "embryonic stage 8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 250."
+ ],
+ "definition": {
+ "val": "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "rapidly extending germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005323",
+ "lbl": "embryonic stage 9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 280."
+ ],
+ "definition": {
+ "val": "Stage 9 begins when mesodermal segmentation becomes (transiently) visible\\, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005324",
+ "lbl": "embryonic stage 10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 290."
+ ],
+ "definition": {
+ "val": "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005325",
+ "lbl": "embryonic stage 11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 310."
+ ],
+ "definition": {
+ "val": "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005326",
+ "lbl": "contracted germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005327",
+ "lbl": "embryonic stage 12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 320."
+ ],
+ "definition": {
+ "val": "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "retracting germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005328",
+ "lbl": "embryonic stage 13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 340."
+ ],
+ "definition": {
+ "val": "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "contracted germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005329",
+ "lbl": "head involution stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "FBdv:00005330"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005330",
+ "lbl": "embryonic stage 14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 350."
+ ],
+ "definition": {
+ "val": "Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "head involution stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005331",
+ "lbl": "dorsal closure stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 330."
+ ],
+ "definition": {
+ "val": "A collective term for stages 13-15.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005332",
+ "lbl": "embryonic stage 15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 360."
+ ],
+ "definition": {
+ "val": "Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005333",
+ "lbl": "late embryonic stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 370."
+ ],
+ "definition": {
+ "val": "Embryonic stages 16-17.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005334",
+ "lbl": "embryonic stage 16",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 380."
+ ],
+ "definition": {
+ "val": "Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005335",
+ "lbl": "embryonic stage 17",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 390."
+ ],
+ "definition": {
+ "val": "Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005336",
+ "lbl": "larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 400."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005337",
+ "lbl": "first instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 410."
+ ],
+ "definition": {
+ "val": "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L1",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "first instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000000"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005338",
+ "lbl": "second instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 420."
+ ],
+ "definition": {
+ "val": "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L2",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "second instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000001"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005339",
+ "lbl": "third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 430."
+ ],
+ "definition": {
+ "val": "The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L3",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "third instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000002"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005340",
+ "lbl": "early third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T11:51:56Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 440."
+ ],
+ "definition": {
+ "val": "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005341",
+ "lbl": "wandering third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T11:55:46Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 460."
+ ],
+ "definition": {
+ "val": "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "late third instar",
+ "xrefs": []
+ },
+ {
+ "pred": "hasBroadSynonym",
+ "val": "post-feeding larva",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005342",
+ "lbl": "prepupal stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 500."
+ ],
+ "definition": {
+ "val": "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005343",
+ "lbl": "prepupal stage P1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 510."
+ ],
+ "definition": {
+ "val": "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P1",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "puparium formation",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "white puparium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "pupal stage P0",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "white prepupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005344",
+ "lbl": "prepupal stage P2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 520."
+ ],
+ "definition": {
+ "val": "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "brown puparium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P2",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005345",
+ "lbl": "prepupal stage P3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 530."
+ ],
+ "definition": {
+ "val": "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "bubble prepupa stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P3",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005346",
+ "lbl": "prepupal stage P4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 540."
+ ],
+ "definition": {
+ "val": "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cryptocephalic pupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005347",
+ "lbl": "prepupal stage P4(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 550."
+ ],
+ "definition": {
+ "val": "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "buoyant stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005348",
+ "lbl": "prepupal stage P4(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 560."
+ ],
+ "definition": {
+ "val": "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "moving bubble stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4(ii)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005349",
+ "lbl": "pupal stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 570. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for Cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head and expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage."
+ ],
+ "definition": {
+ "val": "The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "phanerocephalic pupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005350",
+ "lbl": "pupal stage P5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 580."
+ ],
+ "definition": {
+ "val": "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005351",
+ "lbl": "pupal stage P5(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 590."
+ ],
+ "definition": {
+ "val": "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "Malpighian tubules migrating",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005352",
+ "lbl": "pupal stage P5(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 600."
+ ],
+ "definition": {
+ "val": "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "white Malpighian tubules stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005353",
+ "lbl": "pupal stage P6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 610."
+ ],
+ "definition": {
+ "val": "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "green Malpighian tubules stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005354",
+ "lbl": "pupal stage P7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 620."
+ ],
+ "definition": {
+ "val": "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "yellow body stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005355",
+ "lbl": "pharate adult stage P8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 630."
+ ],
+ "definition": {
+ "val": "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P8",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "yellow-eyed stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005356",
+ "lbl": "pharate adult stage P9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 640."
+ ],
+ "definition": {
+ "val": "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "amber-eyed stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P9",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005357",
+ "lbl": "pharate adult stage P10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 650."
+ ],
+ "definition": {
+ "val": "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P10",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "red-eye bald stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005358",
+ "lbl": "pharate adult stage P11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 660."
+ ],
+ "definition": {
+ "val": "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005359",
+ "lbl": "pharate adult stage P11(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 670."
+ ],
+ "definition": {
+ "val": "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "head bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005360",
+ "lbl": "pharate adult stage P11(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 680."
+ ],
+ "definition": {
+ "val": "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11(ii)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "thoracic bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005361",
+ "lbl": "pharate adult stage P12",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 690."
+ ],
+ "definition": {
+ "val": "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005362",
+ "lbl": "pharate adult stage P12(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 700."
+ ],
+ "definition": {
+ "val": "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12(i)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wing tips grey stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005363",
+ "lbl": "pharate adult stage P12(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 710."
+ ],
+ "definition": {
+ "val": "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12(ii)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wings grey stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005364",
+ "lbl": "pharate adult stage P13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 720."
+ ],
+ "definition": {
+ "val": "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P13",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wings black stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005365",
+ "lbl": "pharate adult stage P14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 730."
+ ],
+ "definition": {
+ "val": "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "mature bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P14",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005366",
+ "lbl": "pharate adult stage P15",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 740."
+ ],
+ "definition": {
+ "val": "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005367",
+ "lbl": "pharate adult stage P15(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 750."
+ ],
+ "definition": {
+ "val": "Tanning of the tergites obscures the Malpighian tubules and the 'yellow body'. Legs begin to twitch; fly is able to walk if puparium is removed prematurely. Ptilinum expands by hydrostatic pressure, opening the operculum. Duration at 25 degrees C: approximately 8 hours, 6 minutes. (211.5-219.6 hours after egg laying; 91.5-99.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "meconium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005368",
+ "lbl": "pharate adult stage P15(ii)",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 760."
+ ],
+ "definition": {
+ "val": "Stage which starts when the operculum opens and ends when eclosion is completed. Duration at 25 degrees C: approximately 24 minutes. (219.6-220 hours after egg laying; 99.6-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "eclosion stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15(ii)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005369",
+ "lbl": "adult stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 770."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from eclosion to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005370",
+ "lbl": "adult stage A1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005373"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 785. The time at which eclosed flies settle down for wing expansion can vary greatly. If they fail to find a suitable site then expansion can be delayed by several hours."
+ ],
+ "definition": {
+ "val": "Newly eclosed adult stage. Animal free of pupal case. Runs rapidly to find site for wing expansion. Wings are folded back and black against a very pale abdomen.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage I",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005371",
+ "lbl": "adult stage A2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005374"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 790."
+ ],
+ "definition": {
+ "val": "Stage, shortly after eclosion, during which the wings expand. During wing expansion, the abdomen pulsates and the hind legs stroke the wings vigorously for several minutes at a time. The stage ends when the wings are folded down over the abdomen, which has become broader and shorter, and the wing cuticle has lost its folds. The stage lasts around 15 minutes at 25'C.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage II",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005412",
+ "lbl": "gamete",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "This should be considered as a type of cell rather than as a stage. Please use FBbt:00005412."
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00006011",
+ "lbl": "pharate adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 625."
+ ],
+ "definition": {
+ "val": "The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355",
+ "FlyBase:FBrf0049147"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00006012",
+ "lbl": "adult stage A3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005375"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 800."
+ ],
+ "definition": {
+ "val": "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage III",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007000",
+ "lbl": "spermatogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-06-05T04:51:08Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 20000."
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0007283"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007001",
+ "lbl": "P-stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-06-05T04:51:40Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 490. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head an expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "metamorphosis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "pupal stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007002",
+ "lbl": "oogenesis stage S11a",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10140."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins and ends when the dorsal appendages begin to form.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007003",
+ "lbl": "oogenesis stage S11b",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10150."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when endochorion begins to form at the anterior pole, a process which includes the beginning of formation of the dorsal appendages. During this stage, the follicle cells secrete membranous vesicles that form irregular extracellular plaques. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007004",
+ "lbl": "third instar larval stage L1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 470."
+ ],
+ "definition": {
+ "val": "Stage which begins when wandering third instar larva stops crawling. The larva everts its anterior spiracles during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007005",
+ "lbl": "third instar larval stage L2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 480."
+ ],
+ "definition": {
+ "val": "The anterior spiracles are fully everted, with 7-9 finger-like projections. The body shortens, withdrawing three apparent abdominal segments and the larva sticks to its substrate.",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "spiracles everted larva",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "white prepupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007006",
+ "lbl": "oogenesis stage S13E",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T06:27:57Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10250."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007007",
+ "lbl": "late third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-12-11T01:19:53Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 450."
+ ],
+ "definition": {
+ "val": "Third instar larva from the beginning of wandering to the beginning of puparium formation.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007008",
+ "lbl": "occurrent",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007009",
+ "lbl": "developmental process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:56:42Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0032502"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007011",
+ "lbl": "embryonic cycle",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:57:41Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.",
+ "xrefs": [
+ "FlyBase:FBrf0049535",
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007012",
+ "lbl": "life stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:59:22Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "life cycle stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007013",
+ "lbl": "age",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-29T12:25:36Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007014",
+ "lbl": "adult age in days",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-29T12:28:05Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Temporal subdivision of adulthood in days post-eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007015",
+ "lbl": "embryonic stage 17(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T11:57:15Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007016",
+ "lbl": "embryonic stage 17(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:00:15Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 392. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007017",
+ "lbl": "embryonic stage 17(iii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:01:18Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 393. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007018",
+ "lbl": "embryonic stage 17(iv)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:03:14Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 394. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007019",
+ "lbl": "third instar - uncleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994)."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007020",
+ "lbl": "third instar - partially cleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994)."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007021",
+ "lbl": "third instar - cleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage when the larva has cleared its gut contents.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007022",
+ "lbl": "embryonic cycle interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The interphase (GO:0051325) of an embryonic cycle.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007023",
+ "lbl": "embryonic cycle M-phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The M-phase (GO:0000279) of an embryonic cycle.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007024",
+ "lbl": "biological process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0008150"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007025",
+ "lbl": "immature adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-01-08T20:06:59Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 782."
+ ],
+ "definition": {
+ "val": "The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007026",
+ "lbl": "mature adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-01-10T13:03:54Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Life stage from the end of adult stage A3, when tanning is complete, to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007075",
+ "lbl": "day 0 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 780."
+ ],
+ "definition": {
+ "val": "The day of eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007076",
+ "lbl": "day 1 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 810."
+ ],
+ "definition": {
+ "val": "1st day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007077",
+ "lbl": "day 2 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 820."
+ ],
+ "definition": {
+ "val": "2nd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007078",
+ "lbl": "day 3 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 830."
+ ],
+ "definition": {
+ "val": "3rd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007079",
+ "lbl": "day 4 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 840."
+ ],
+ "definition": {
+ "val": "4th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007080",
+ "lbl": "day 5 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 850."
+ ],
+ "definition": {
+ "val": "5th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007081",
+ "lbl": "day 6 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 860."
+ ],
+ "definition": {
+ "val": "6th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007082",
+ "lbl": "day 7 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 870."
+ ],
+ "definition": {
+ "val": "7th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007083",
+ "lbl": "day 8 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 880."
+ ],
+ "definition": {
+ "val": "8th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007084",
+ "lbl": "day 9 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 890."
+ ],
+ "definition": {
+ "val": "9th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007085",
+ "lbl": "day 10 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 900."
+ ],
+ "definition": {
+ "val": "10th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007086",
+ "lbl": "day 11 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 910."
+ ],
+ "definition": {
+ "val": "11th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007087",
+ "lbl": "day 12 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 920."
+ ],
+ "definition": {
+ "val": "12th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
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+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007128",
+ "lbl": "day 53 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1330."
+ ],
+ "definition": {
+ "val": "53rd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007129",
+ "lbl": "day 54 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1340."
+ ],
+ "definition": {
+ "val": "54th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007130",
+ "lbl": "day 55 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1350."
+ ],
+ "definition": {
+ "val": "55th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007131",
+ "lbl": "day 56 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1360."
+ ],
+ "definition": {
+ "val": "56th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007132",
+ "lbl": "day 57 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1370."
+ ],
+ "definition": {
+ "val": "57th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007133",
+ "lbl": "day 58 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1380."
+ ],
+ "definition": {
+ "val": "58th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007134",
+ "lbl": "day 59 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1390."
+ ],
+ "definition": {
+ "val": "59th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007135",
+ "lbl": "day 60 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1400."
+ ],
+ "definition": {
+ "val": "60th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00014201",
+ "lbl": "early extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 270."
+ ],
+ "definition": {
+ "val": "A collective term for stages 9 and 10.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00018001",
+ "lbl": "substage_of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "substage_of"
+ }
+ ],
+ "comments": [
+ "Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO."
+ ],
+ "xrefs": [
+ {
+ "val": "FBdv:00018001"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000087",
+ "lbl": "mitotic M phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "M phase of mitotic cell cycle",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "M-phase of mitotic cell cycle",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000278",
+ "lbl": "mitotic cell cycle",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0007067"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle."
+ ],
+ "definition": {
+ "val": "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.",
+ "xrefs": [
+ "GOC:mah",
+ "ISBN:0815316194",
+ "Reactome:69278"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_drosophila",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_yeast"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "mitosis",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Mitosis"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000279",
+ "lbl": "M phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "M-phase",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:M_phase"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000280",
+ "lbl": "nuclear division",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "karyokinesis",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0003674",
+ "lbl": "molecular_function",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "molecular process"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0006996",
+ "lbl": "organelle organization",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-12-19T15:25:51Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:1902589"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_candida",
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "organelle organisation",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "single organism organelle organization",
+ "xrefs": [
+ "GOC:TermGenie"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "organelle organization and biogenesis",
+ "xrefs": [
+ "GOC:dph",
+ "GOC:jl",
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism organelle organization",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0007049",
+ "lbl": "cell cycle",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.",
+ "xrefs": [
+ "GOC:go_curators",
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate",
+ "http://purl.obolibrary.org/obo/go#goslim_agr",
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_candida",
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cell-division cycle",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Cell_cycle"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0007275",
+ "lbl": "multicellular organism development",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term was 'developmental process'."
+ ],
+ "definition": {
+ "val": "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",
+ "xrefs": [
+ "GOC:dph",
+ "GOC:ems",
+ "GOC:isa_complete",
+ "GOC:tb"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0008150",
+ "lbl": "biological_process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-09-19T15:05:24Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0000004"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0007582"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044699"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this."
+ ],
+ "definition": {
+ "val": "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.",
+ "xrefs": [
+ "GOC:pdt"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_candida",
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_metagenomics",
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_plant",
+ "http://purl.obolibrary.org/obo/go#goslim_pombe",
+ "http://purl.obolibrary.org/obo/go#goslim_yeast"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "biological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "physiological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single organism process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism process",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Biological_process"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0009790",
+ "lbl": "embryo development",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0009795"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.",
+ "xrefs": [
+ "GOC:go_curators",
+ "GOC:isa_complete",
+ "GOC:mtg_sensu"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate",
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "embryogenesis and morphogenesis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryogenesis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonal development",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Embryogenesis"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0009987",
+ "lbl": "cellular process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-12-11T16:56:55Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0008151"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044763"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0050875"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",
+ "xrefs": [
+ "GOC:go_curators",
+ "GOC:isa_complete"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cell physiology",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular physiological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "cell growth and/or maintenance",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism cellular process",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0016043",
+ "lbl": "cellular component organization",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044235"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0071842"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.",
+ "xrefs": [
+ "GOC:ai",
+ "GOC:jl",
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_agr",
+ "http://purl.obolibrary.org/obo/go#goslim_mouse",
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cell organisation",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation at cellular level",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation in other organism",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organization at cellular level",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organization in other organism",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "cell organization and biogenesis",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0022402",
+ "lbl": "cell cycle process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.",
+ "xrefs": [
+ "GOC:isa_complete",
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0022403",
+ "lbl": "cell cycle phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0032501",
+ "lbl": "multicellular organismal process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002161",
+ "val": "http://purl.obolibrary.org/obo/NCBITaxon_4896"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002161",
+ "val": "http://purl.obolibrary.org/obo/NCBITaxon_4932"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-09-19T16:07:47Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044707"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0050874"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "Any biological process, occurring at the level of a multicellular organism, pertinent to its function.",
+ "xrefs": [
+ "GOC:curators",
+ "GOC:dph",
+ "GOC:isa_complete",
+ "GOC:tb"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "organismal physiological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-multicellular organism process",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0032502",
+ "lbl": "developmental process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-12-19T12:21:31Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044767"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.",
+ "xrefs": [
+ "GOC:isa_complete"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_agr",
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon",
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "development",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism developmental process",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0044848",
+ "lbl": "biological phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2014-07-16T13:12:40Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase."
+ ],
+ "definition": {
+ "val": "A distinct period or stage in a biological process or cycle.",
+ "xrefs": [
+ "GOC:jl"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0045448",
+ "lbl": "mitotic cell cycle, embryonic",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.",
+ "xrefs": [
+ "GOC:go_curators"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0048285",
+ "lbl": "organelle fission",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The creation of two or more organelles by division of one organelle.",
+ "xrefs": [
+ "GOC:jid"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_yeast"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0048856",
+ "lbl": "anatomical structure development",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.",
+ "xrefs": [
+ "GO_REF:0000021"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "development of an anatomical structure",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0051325",
+ "lbl": "interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "resting phase",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "karyostasis",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Interphase"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0051329",
+ "lbl": "mitotic interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "interphase of mitotic cell cycle",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0071840",
+ "lbl": "cellular component organization or biogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "mah"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-10T01:39:16Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0071841"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon",
+ "http://purl.obolibrary.org/obo/go#goslim_metagenomics"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation or biogenesis",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation or biogenesis at cellular level",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organization or biogenesis at cellular level",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0098763",
+ "lbl": "mitotic cell cycle phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0140014",
+ "lbl": "mitotic nuclear division",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000233",
+ "val": "https://github.com/geneontology/go-ontology/issues/19910"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "pg"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-03-23T14:44:23Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",
+ "xrefs": [
+ "ISBN:0198547684"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "mitosis",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_1903047",
+ "lbl": "mitotic cell cycle process",
+ "meta": {
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2014-05-22T14:22:34Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that is part of the mitotic cell cycle.",
+ "xrefs": [
+ "GOC:TermGenie",
+ "GOC:mtg_cell_cycle",
+ "GO_REF:0000060"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
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+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/IAO_0000115",
+ "lbl": "definition",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "http://purl.obolibrary.org/obo/IAO_0000122"
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+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/PATO_0000001",
+ "lbl": "quality",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "quality (PATO)"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0000056",
+ "lbl": "participates in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "participates in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this blood clot participates in this blood coagulation"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this input material (or this output material) participates in this process"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this investigator participates in this investigation"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "participates_in"
+ }
+ ],
+ "definition": {
+ "val": "a relation between a continuant and a process, in which the continuant is somehow involved in the process",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0000057",
+ "lbl": "has participant",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "has participant"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this blood coagulation has participant this blood clot"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this investigation has participant this investigator"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this process has participant this input material (or this output material)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has_participant"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/source",
+ "val": "http://www.obofoundry.org/ro/#OBO_REL:has_participant"
+ }
+ ],
+ "definition": {
+ "val": "a relation between a process and a continuant, in which the continuant is somehow involved in the process",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002012",
+ "lbl": "occurent part of",
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+ "val": "FlyBase_development_CV"
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+ {
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+ "val": "occurent_part_of"
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+ ],
+ "definition": {
+ "val": "A part of relation that applies only between occurents.",
+ "xrefs": []
+ },
+ "xrefs": [
+ {
+ "val": "RO:0002012"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002013",
+ "lbl": "has regulatory component activity",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
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+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:30:46Z"
+ }
+ ],
+ "definition": {
+ "val": "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002014",
+ "lbl": "has negative regulatory component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:31:01Z"
+ }
+ ],
+ "comments": [
+ "By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'."
+ ],
+ "definition": {
+ "val": "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002015",
+ "lbl": "has positive regulatory component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:31:17Z"
+ }
+ ],
+ "comments": [
+ "By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'."
+ ],
+ "definition": {
+ "val": "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002017",
+ "lbl": "has component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:44:33Z"
+ }
+ ],
+ "comments": [
+ "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B."
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002018",
+ "lbl": "has component process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:49:21Z"
+ }
+ ],
+ "definition": {
+ "val": "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002022",
+ "lbl": "directly regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-17T13:52:24Z"
+ }
+ ],
+ "comments": [
+ "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2."
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002023",
+ "lbl": "directly negatively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-17T13:52:38Z"
+ }
+ ],
+ "definition": {
+ "val": "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002024",
+ "lbl": "directly positively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-17T13:52:47Z"
+ }
+ ],
+ "definition": {
+ "val": "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002025",
+ "lbl": "has effector activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-22T14:14:36Z"
+ }
+ ],
+ "comments": [
+ "This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations."
+ ],
+ "definition": {
+ "val": "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002084",
+ "lbl": "during which ends",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ }
+ ],
+ "comments": [
+ "Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range."
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002085",
+ "lbl": "encompasses",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "di"
+ }
+ ],
+ "comments": [
+ "Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range."
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002086",
+ "lbl": "ends after",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ }
+ ],
+ "comments": [
+ "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002087",
+ "lbl": "immediately_preceded_by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "starts_at_end_of"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "immediately_preceded_by"
+ }
+ ],
+ "comments": [
+ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002087"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002088",
+ "lbl": "during which starts",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ }
+ ],
+ "comments": [
+ "Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range."
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002090",
+ "lbl": "ends_at_start_of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "ends_at_start_of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "meets"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002575",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000063"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "ends_at_start_of"
+ }
+ ],
+ "comments": [
+ "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002090"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002091",
+ "lbl": "starts during",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "io"
+ }
+ ],
+ "comments": [
+ "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002092",
+ "lbl": "happens during",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "d"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "during"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "happens_during"
+ }
+ ],
+ "comments": [
+ "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002092"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002093",
+ "lbl": "ends during",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "o"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "overlaps"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "ends_during"
+ }
+ ],
+ "comments": [
+ "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). "
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002093"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002131",
+ "lbl": "overlaps",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000424",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "overlaps"
+ }
+ ],
+ "definition": {
+ "val": "x overlaps y if and only if there exists some z such that x has part z and z part of y",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002131"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002180",
+ "lbl": "has component",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Submissions:Componency"
+ }
+ ],
+ "definition": {
+ "val": "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002202",
+ "lbl": "develops from",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Melissa Haendel"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Terry Meehan"
+ }
+ ],
+ "comments": [
+ "This is the transitive form of the develops from relation"
+ ],
+ "definition": {
+ "val": "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002203",
+ "lbl": "develops into",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Terry Meehan"
+ }
+ ],
+ "definition": {
+ "val": "inverse of develops from",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002211",
+ "lbl": "regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Hill"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Tanya Berardini"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "GO"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Regulation precludes parthood; the regulatory process may not be within the regulated process."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "regulates (processual)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000600",
+ "val": "false"
+ }
+ ],
+ "definition": {
+ "val": "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002212",
+ "lbl": "negatively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "negatively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002211"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002213",
+ "lbl": "positively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "positively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002211"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002215",
+ "lbl": "capable of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "osteoclast SubClassOf 'capable of' some 'bone resorption'"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has function realized in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/20123131"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/21208450"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"."
+ }
+ ],
+ "definition": {
+ "val": "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. ",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002216",
+ "lbl": "capable of part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has function in"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "https://github.com/oborel/obo-relations/wiki/ROGuide#defining-property-chains-involving-reflexivity"
+ }
+ ],
+ "definition": {
+ "val": "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002222",
+ "lbl": "temporally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "https://en.wikipedia.org/wiki/Allen%27s_interval_algebra"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends."
+ },
+ {
+ "pred": "http://purl.org/dc/terms/source",
+ "val": "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1"
+ }
+ ],
+ "comments": [
+ "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations."
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002233",
+ "lbl": "has input",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "consumes"
+ }
+ ],
+ "definition": {
+ "val": "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002254",
+ "lbl": "has developmental contribution from",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has developmental contribution from y iff x has some part z such that z develops from y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002255",
+ "lbl": "developmentally contributes to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of has developmental contribution from",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002258",
+ "lbl": "developmentally preceded by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "false"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "In general you should not use this relation to make assertions - use one of the more specific relations below this one"
+ }
+ ],
+ "comments": [
+ "This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from"
+ ],
+ "definition": {
+ "val": "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002263",
+ "lbl": "acts upstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision."
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of"
+ }
+ ],
+ "definition": {
+ "val": "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002264",
+ "lbl": "acts upstream of or within",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway."
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within"
+ }
+ ],
+ "definition": {
+ "val": "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "affects",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002286",
+ "lbl": "developmentally succeeded by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "Inverse of developmentally preceded by",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002304",
+ "lbl": "causally upstream of, positive effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002411"
+ },
+ {
+ "pred": "http://purl.org/dc/terms/creator",
+ "val": "cjm"
+ }
+ ],
+ "comments": [
+ "holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002305",
+ "lbl": "causally upstream of, negative effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002411"
+ },
+ {
+ "pred": "http://purl.org/dc/terms/creator",
+ "val": "cjm"
+ }
+ ],
+ "comments": [
+ "holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002314",
+ "lbl": "inheres in part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Because part_of is transitive, inheres in is a sub-relation of inheres in part of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "https://github.com/oborel/obo-relations/wiki/ROGuide#defining-property-chains-involving-reflexivity"
+ }
+ ],
+ "definition": {
+ "val": "q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002323",
+ "lbl": "mereotopologically related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ }
+ ],
+ "definition": {
+ "val": "A mereological relationship or a topological relationship",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002324",
+ "lbl": "developmentally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development"
+ }
+ ],
+ "definition": {
+ "val": "A relationship that holds between entities participating in some developmental process (GO:0032502)",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002327",
+ "lbl": "enables",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "a particular instances of akt-2 enables some instance of protein kinase activity"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "catalyzes"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "executes"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "is catalyzing"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "is executing"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time."
+ }
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002328",
+ "lbl": "functionally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This is a grouping relation that collects relations used for the purpose of connecting structure and function"
+ }
+ ],
+ "definition": {
+ "val": "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002329",
+ "lbl": "part of structure that is capable of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "false"
+ }
+ ],
+ "definition": {
+ "val": "this relation holds between c and p when c is part of some c', and c' is capable of p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002331",
+ "lbl": "involved in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "actively involved in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "enables part of"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Involved_in"
+ }
+ ],
+ "definition": {
+ "val": "c involved_in p if and only if c enables some process p', and p' is part of p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002333",
+ "lbl": "enabled by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of enables",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002334",
+ "lbl": "regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "regulated by (processual)"
+ }
+ ],
+ "definition": {
+ "val": "inverse of regulates",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002335",
+ "lbl": "negatively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of negatively regulates",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002336",
+ "lbl": "positively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of positively regulates",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002352",
+ "lbl": "input of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of has input",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259",
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002384",
+ "lbl": "has developmental potential involving",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002385",
+ "lbl": "has potential to developmentally contribute to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002387",
+ "lbl": "has potential to develop into",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has the potential to develop into y iff x develops into y or if x is capable of developing into y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002388",
+ "lbl": "has potential to directly develop into",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002404",
+ "lbl": "causally downstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of upstream of",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002405",
+ "lbl": "immediately causally downstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002410",
+ "lbl": "causally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ }
+ ],
+ "definition": {
+ "val": "This relation groups causal relations between material entities and causal relations between processes",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002411",
+ "lbl": "causally upstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002412",
+ "lbl": "immediately causally upstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002575",
+ "val": "http://purl.obolibrary.org/obo/RO_0002411"
+ }
+ ],
+ "definition": {
+ "val": "p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002418",
+ "lbl": "causally upstream of or within",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "influences (processual)"
+ }
+ ],
+ "definition": {
+ "val": "p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "affects",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002427",
+ "lbl": "causally downstream of or within",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "inverse of causally upstream of or within",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002428",
+ "lbl": "involved in regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "c involved in regulation of p if c is involved in some p' and p' regulates some p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002429",
+ "lbl": "involved in positive regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002428"
+ }
+ ],
+ "definition": {
+ "val": "c involved in regulation of p if c is involved in some p' and p' positively regulates some p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002430",
+ "lbl": "involved in negative regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002428"
+ }
+ ],
+ "definition": {
+ "val": "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002431",
+ "lbl": "involved in or involved in regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "OWL does not allow defining object properties via a Union"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "involved in or reguates"
+ }
+ ],
+ "definition": {
+ "val": "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002432",
+ "lbl": "is active in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "A protein that enables activity in a cytosol."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "executes activity in"
+ }
+ ],
+ "comments": [
+ ""
+ ],
+ "definition": {
+ "val": "c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.",
+ "xrefs": [
+ "GOC:cjm",
+ "GOC:dos"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "enables activity in",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002434",
+ "lbl": "interacts with",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Considering relabeling as 'pairwise interacts with'"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules."
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/MI_0914"
+ },
+ {
+ "pred": "http://xmlns.com/foaf/0.1/page",
+ "val": "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
+ }
+ ],
+ "definition": {
+ "val": "A relationship that holds between two entities in which the processes executed by the two entities are causally connected.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "in pairwise interaction with",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002436",
+ "lbl": "molecularly interacts with",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "binds"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "molecularly binds with"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/ECO_0000353"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/MI_0915"
+ }
+ ],
+ "definition": {
+ "val": "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002447",
+ "lbl": "phosphorylates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Axiomatization to GO to be added later"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y."
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002448",
+ "lbl": "directly regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ }
+ ],
+ "definition": {
+ "val": "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "molecularly controls",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002449",
+ "lbl": "directly negatively regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "directly inhibits"
+ }
+ ],
+ "definition": {
+ "val": "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "molecularly decreases activity of",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002450",
+ "lbl": "directly positively regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "directly activates"
+ }
+ ],
+ "definition": {
+ "val": "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "molecularly increases activity of",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002464",
+ "lbl": "helper property (not for use in curation)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning."
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002479",
+ "lbl": "has part that occurs in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002481",
+ "lbl": "is kinase activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002500",
+ "lbl": "causal agent in process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "A relationship between a material entity and a process where the material entity has some causal role that influences the process",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002501",
+ "lbl": "causal relation between processes",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ }
+ ],
+ "definition": {
+ "val": "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002502",
+ "lbl": "depends on",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000169"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002506",
+ "lbl": "causal relation between entities",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002559",
+ "lbl": "causally influenced by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "causally influenced by (entity-centric)"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002563",
+ "lbl": "interaction relation helper property",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29"
+ },
+ {
+ "pred": "http://xmlns.com/foaf/0.1/page",
+ "val": "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002564",
+ "lbl": "molecular interaction relation helper property",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002566",
+ "lbl": "causally influences",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "causally influences (entity-centric)"
+ }
+ ],
+ "definition": {
+ "val": "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002573",
+ "lbl": "has modifier",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the \"modifiers\" are."
+ }
+ ],
+ "definition": {
+ "val": "A relation that holds between an attribute or a qualifier and another attribute.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002578",
+ "lbl": "directly regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "directly regulates (processual)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002575",
+ "val": "http://purl.obolibrary.org/obo/RO_0002211"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002581",
+ "lbl": "is a defining property chain axiom",
+ "meta": {
+ "definition": {
+ "val": "If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002582",
+ "lbl": "is a defining property chain axiom where second argument is reflexive",
+ "meta": {
+ "definition": {
+ "val": "If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002584",
+ "lbl": "has part structure that is capable of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002595",
+ "lbl": "causal relation between material entity and a process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002596",
+ "lbl": "capable of regulating",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "pyrethroid -> growth"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Holds between c and p if and only if c is capable of some activity a, and a regulates p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002597",
+ "lbl": "capable of negatively regulating",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002598",
+ "lbl": "capable of positively regulating",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "renin -> arteriolar smooth muscle contraction"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002608",
+ "lbl": "process has causal agent",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Inverse of 'causal agent in process'",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002629",
+ "lbl": "directly positively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "directly positively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002578"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002630",
+ "lbl": "directly negatively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "directly negatively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002578"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004031",
+ "lbl": "enables subfunction",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-25T23:20:13Z"
+ }
+ ],
+ "definition": {
+ "val": "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004032",
+ "lbl": "acts upstream of or within, positive effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002264"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-26T23:49:30Z"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect"
+ }
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004033",
+ "lbl": "acts upstream of or within, negative effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002264"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-26T23:49:51Z"
+ }
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004034",
+ "lbl": "acts upstream of, positive effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002263"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-26T23:53:14Z"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of,_positive_effect"
+ }
+ ],
+ "definition": {
+ "val": "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004035",
+ "lbl": "acts upstream of, negative effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002263"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-26T23:53:22Z"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of,_negative_effect"
+ }
+ ],
+ "definition": {
+ "val": "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004046",
+ "lbl": "causally upstream of or within, negative effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002418"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-03-13T23:55:05Z"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004047",
+ "lbl": "causally upstream of or within, positive effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002418"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-03-13T23:55:19Z"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0011002",
+ "lbl": "regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ }
+ ],
+ "definition": {
+ "val": "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/fbdv#systematic_synonym",
+ "lbl": "Systematic synonym",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasScope",
+ "val": "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"
+ }
+ ]
+ },
+ "type": "PROPERTY"
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- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002263",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002411" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0000057",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000051", "http://purl.obolibrary.org/obo/RO_0000057" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002131",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000051", "http://purl.obolibrary.org/obo/RO_0002131" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002131",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002131", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0004034",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002304" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002264",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002418" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0004033",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0004046" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002596",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/RO_0002211" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002450",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002629", "http://purl.obolibrary.org/obo/RO_0002333" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002327",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002017" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002086",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002093", "http://purl.obolibrary.org/obo/BFO_0000062" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002597",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/RO_0002212" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002091", "http://purl.obolibrary.org/obo/BFO_0000062" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002216",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002566",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002411", "http://purl.obolibrary.org/obo/RO_0002333" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002428",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002331", "http://purl.obolibrary.org/obo/RO_0002211" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000066",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000050", "http://purl.obolibrary.org/obo/BFO_0000066" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002598",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/RO_0002213" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0004031",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/BFO_0000051" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002131",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000051", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002211",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002211", "http://purl.obolibrary.org/obo/RO_0002025" ]
- } ]
- } ]
-}
\ No newline at end of file
+ ]
+ }
+ ]
+}
diff --git a/fbdv-full.obo b/fbdv-full.obo
index bfc59c1..58a14ab 100644
--- a/fbdv-full.obo
+++ b/fbdv-full.obo
@@ -1,6 +1,6 @@
format-version: 1.2
-data-version: fbdv/releases/2021-01-13/fbdv-full.owl
-date: 13:01:2021 12:24
+data-version: fbdv/releases/2021-03-10/fbdv-full.owl
+date: 10:03:2021 10:38
subsetdef: gocheck_do_not_annotate ""
subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation"
subsetdef: gocheck_do_not_manually_annotate ""
@@ -50,7 +50,7 @@ property_value: IAO:0000700 FBdv:00000000
property_value: IAO:0000700 FBdv:00005259
property_value: IAO:0000700 FBdv:00007013
property_value: IAO:0000700 FBdv:00007024
-property_value: owl:versionInfo "2021-01-13" xsd:string
+property_value: owl:versionInfo "2021-03-10" xsd:string
[Term]
id: BFO:0000002
@@ -397,6 +397,7 @@ comment: Temporal ordering number - 10.
is_a: FBdv:00005259 ! developmental stage
relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
relationship: substage_of FBdv:00005286 ! egg stage
+relationship: substage_of FBdv:00005289 ! embryonic stage
[Term]
id: FBdv:00005289
@@ -404,7 +405,7 @@ name: embryonic stage
def: "The stage of the Drosophila life-cycle from fertilization to hatching." [FBC:DOS]
comment: Temporal ordering number - 20.
is_a: FBdv:00007012 ! life stage
-relationship: immediately_preceded_by FBdv:00005288 ! fertilized egg stage
+relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
[Term]
id: FBdv:00005290
@@ -850,6 +851,7 @@ def: "The first larval instar begins at hatching and ends at the first larval mo
comment: Temporal ordering number - 410.
synonym: "first instar larva" EXACT []
synonym: "L1" EXACT []
+xref: UBERON:8000000
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005289 ! embryonic stage
relationship: immediately_preceded_by FBdv:00005333 ! late embryonic stage
@@ -864,6 +866,7 @@ def: "The second larval instar begins at the first larval molt and ends at the s
comment: Temporal ordering number - 420.
synonym: "L2" EXACT []
synonym: "second instar larva" EXACT []
+xref: UBERON:8000001
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005337 ! first instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -875,6 +878,7 @@ def: "The third larval instar begins at the second larval molt and ends at pupar
comment: Temporal ordering number - 430.
synonym: "L3" EXACT []
synonym: "third instar larva" RELATED []
+xref: UBERON:8000002
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005338 ! second instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -2711,7 +2715,6 @@ id: RO:0002211
name: regulates
def: "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
-subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
property_value: IAO:0000114 IAO:0000125
@@ -2737,7 +2740,6 @@ id: RO:0002212
name: negatively regulates
def: "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
-subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
property_value: IAO:0000117 "Chris Mungall" xsd:string
@@ -2753,7 +2755,6 @@ id: RO:0002213
name: positively regulates
def: "Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
-subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
property_value: IAO:0000117 "Chris Mungall" xsd:string
@@ -3709,5 +3710,5 @@ comment: Creating this relation as a temporary fix, pending adding the axiom occ
xref: FBdv:00018001
is_transitive: true
is_a: happens_during ! happens during
-is_a: occurent_part_of ! occurent part of
+is_a: occurent_part_of ! occurent_part_of
diff --git a/fbdv-full.owl b/fbdv-full.owl
index 362fa7c..a39be43 100644
--- a/fbdv-full.owl
+++ b/fbdv-full.owl
@@ -18,7 +18,7 @@
xmlns:subsets="http://purl.obolibrary.org/obo/ro/subsets#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
-
+
@@ -31,10 +31,10 @@
FlyBase Developmental Ontology (FBdv)
https://creativecommons.org/licenses/by/3.0/
* FBdv:$sequence(8,7000,10000)$
- 13:01:2021 12:24
+ 10:03:2021 10:38
FlyBase_development_CV
1.2
- 2021-01-13
+ 2021-03-10
@@ -506,42 +506,18 @@
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
@@ -1404,7 +1380,6 @@ A continuant cannot have an occurrent as part: use 'participates in'.
regulates (processual)
false
-
regulates
@@ -1424,7 +1399,6 @@ A continuant cannot have an occurrent as part: use 'participates in'.
negatively regulates (process to process)
-
negatively regulates
@@ -1449,7 +1423,6 @@ A continuant cannot have an occurrent as part: use 'participates in'.
positively regulates (process to process)
-
positively regulates
@@ -3830,6 +3803,12 @@ For example, A and B may be gene products and binding of B by A positively regul
+
+
+
+
+
+
@@ -3851,7 +3830,7 @@ For example, A and B may be gene products and binding of B by A positively regul
-
+
The stage of the Drosophila life-cycle from fertilization to hatching.
@@ -5412,6 +5391,7 @@ For example, A and B may be gene products and binding of B by A positively regul
The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).
+ UBERON:8000000
L1
first instar larva
FlyBase_development_CV
@@ -5445,6 +5425,7 @@ For example, A and B may be gene products and binding of B by A positively regul
The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).
+ UBERON:8000001
L2
second instar larva
FlyBase_development_CV
@@ -5478,6 +5459,7 @@ For example, A and B may be gene products and binding of B by A positively regul
The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).
+ UBERON:8000002
L3
FlyBase_development_CV
third instar larva
@@ -9924,7 +9906,7 @@ For example, A and B may be gene products and binding of B by A positively regul
A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
- GOC:pdt
+ GOC:pdt
diff --git a/fbdv-non-classified.json b/fbdv-non-classified.json
index 59da282..836126e 100644
--- a/fbdv-non-classified.json
+++ b/fbdv-non-classified.json
@@ -1,10464 +1,14621 @@
{
- "graphs" : [ {
- "nodes" : [ {
- "id" : "http://purl.obolibrary.org/obo/GO_0003674",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "molecular process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "molecular_function"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0000280",
- "meta" : {
- "definition" : {
- "val" : "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.",
- "xrefs" : [ "GOC:mah" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ],
- "synonyms" : [ {
- "pred" : "hasRelatedSynonym",
- "val" : "karyokinesis",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "nuclear division"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005321",
- "meta" : {
- "definition" : {
- "val" : "Stages during which the germ band is extended - 9-12.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 260." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "extended germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005322",
- "meta" : {
- "definition" : {
- "val" : "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 250." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "rapidly extending germ band stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005320",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005314",
- "meta" : {
- "definition" : {
- "val" : "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "FlyBase:FBrf0039741" ]
- },
- "comments" : [ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "embryonic cycle 14 M-phase",
- "xrefs" : [ "FBC:DOS" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005315",
- "meta" : {
- "definition" : {
- "val" : "The 15th cell cycle of embryogenesis. Asynchronous.",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "second blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005312",
- "meta" : {
- "definition" : {
- "val" : "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "FlyBase:FBrf0049535", "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "first blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005313",
- "meta" : {
- "definition" : {
- "val" : "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "[FlyBase:FBrf0039741" ]
- },
- "comments" : [ "Temporal ordering number - 256." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "embryonic cycle 14 interphase",
- "xrefs" : [ "FBC:DOS" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005318",
- "meta" : {
- "definition" : {
- "val" : "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 230." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 6"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005319",
- "meta" : {
- "definition" : {
- "val" : "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 240." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005316",
- "meta" : {
- "definition" : {
- "val" : "The 16th cell cycle division of embryogenesis. Asynchronous.",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "third blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
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- "id" : "http://purl.obolibrary.org/obo/RO_0002608",
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- "val" : "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).",
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- "comments" : [ "Temporal ordering number - 210." ],
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- "val" : "Wikipedia:Embryogenesis"
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- "val" : "embryogenesis and morphogenesis",
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- "pred" : "hasExactSynonym",
- "val" : "embryogenesis",
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- "val" : "GO:0009795"
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- "val" : "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- },
- "comments" : [ "Temporal ordering number - 180." ],
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- "definition" : {
- "val" : "Embryonic stages 4 and 5.",
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- },
- "comments" : [ "Temporal ordering number - 160." ],
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- "val" : "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).",
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- },
- "comments" : [ "Temporal ordering number - 140." ],
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- "val" : "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- },
- "comments" : [ "Temporal ordering number - 150." ],
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- "definition" : {
- "val" : "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- },
- "comments" : [ "Temporal ordering number - 185." ],
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- "val" : "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- "comments" : [ "Temporal ordering number - 190." ],
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- "type" : "CLASS",
- "lbl" : "syncytial blastoderm stage"
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- "definition" : {
- "val" : "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).",
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- "comments" : [ "Temporal ordering number - 170." ],
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- "val" : "syncytial blastoderm stage",
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- "pred" : "hasExactSynonym",
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- "lbl" : "embryonic stage 4"
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- "lbl" : "has_related_synonym"
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- "definition" : {
- "val" : "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- },
- "comments" : [ "Temporal ordering number - 200." ],
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- "lbl" : "embryonic cycle 13"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007081",
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- "definition" : {
- "val" : "6th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 860." ],
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- "type" : "CLASS",
- "lbl" : "day 6 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007080",
- "meta" : {
- "definition" : {
- "val" : "5th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 850." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "day 5 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007085",
- "meta" : {
- "definition" : {
- "val" : "10th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 900." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "day 10 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007084",
- "meta" : {
- "definition" : {
- "val" : "9th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 890." ],
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- "type" : "CLASS",
- "lbl" : "day 9 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007083",
- "meta" : {
- "definition" : {
- "val" : "8th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 880." ],
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- "type" : "CLASS",
- "lbl" : "day 8 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007082",
- "meta" : {
- "definition" : {
- "val" : "7th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 870." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "day 7 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007089",
- "meta" : {
- "definition" : {
- "val" : "14th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 940." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "day 14 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005340",
- "meta" : {
- "definition" : {
- "val" : "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
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- "comments" : [ "Temporal ordering number - 440." ],
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- "val" : "david"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-11-13T11:51:56Z"
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- },
- "type" : "CLASS",
- "lbl" : "early third instar larval stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007088",
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- "definition" : {
- "val" : "13th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 930." ],
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- "type" : "CLASS",
- "lbl" : "day 13 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007087",
- "meta" : {
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- "val" : "12th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 920." ],
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- "type" : "CLASS",
- "lbl" : "day 12 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007086",
- "meta" : {
- "definition" : {
- "val" : "11th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 910." ],
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- "lbl" : "day 11 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005343",
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- "val" : "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 510." ],
- "synonyms" : [ {
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- "val" : "pupal stage P0",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
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- "pred" : "hasNarrowSynonym",
- "val" : "white prepupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
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- "pred" : "hasExactSynonym",
- "val" : "pupal stage P1",
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- "pred" : "hasExactSynonym",
- "val" : "puparium formation",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
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- "pred" : "hasExactSynonym",
- "val" : "white puparium stage",
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- "lbl" : "prepupal stage P1"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005344",
- "meta" : {
- "definition" : {
- "val" : "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 520." ],
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- "val" : "brown puparium stage",
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- "lbl" : "prepupal stage P2"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005341",
- "meta" : {
- "definition" : {
- "val" : "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 460." ],
- "synonyms" : [ {
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- "val" : "late third instar",
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- "pred" : "hasBroadSynonym",
- "val" : "post-feeding larva",
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- "val" : "2008-11-13T11:55:46Z"
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- "type" : "CLASS",
- "lbl" : "wandering third instar larval stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005342",
- "meta" : {
- "definition" : {
- "val" : "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 500." ],
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- "lbl" : "prepupal stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005336",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.",
- "xrefs" : [ "FBC:DOS" ]
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- "comments" : [ "Temporal ordering number - 400." ],
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- "val" : "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).",
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- },
- "comments" : [ "Temporal ordering number - 410." ],
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- "val" : "first instar larva",
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- "val" : "Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).",
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- },
- "comments" : [ "Temporal ordering number - 380." ],
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- "definition" : {
- "val" : "Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).",
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- },
- "comments" : [ "Temporal ordering number - 390." ],
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- "definition" : {
- "val" : "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).",
- "xrefs" : [ "FlyBase:FBrf0007733" ]
- },
- "comments" : [ "Temporal ordering number - 420." ],
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- "val" : "L2",
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- }, {
- "pred" : "hasExactSynonym",
- "val" : "second instar larva",
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- "lbl" : "second instar larval stage"
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- "definition" : {
- "val" : "The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).",
- "xrefs" : [ "FlyBase:FBrf0007733" ]
- },
- "comments" : [ "Temporal ordering number - 430." ],
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- "val" : "L3",
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- "pred" : "hasRelatedSynonym",
- "val" : "third instar larva",
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- "id" : "http://purl.obolibrary.org/obo/GO_0016043",
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- "definition" : {
- "val" : "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.",
- "xrefs" : [ "GOC:ai", "GOC:jl", "GOC:mah" ]
- },
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- "val" : "cellular component organization at cellular level",
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- }, {
- "pred" : "hasExactSynonym",
- "val" : "cellular component organization in other organism",
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- }, {
- "pred" : "hasExactSynonym",
- "val" : "cell organisation",
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- }, {
- "pred" : "hasExactSynonym",
- "val" : "cellular component organisation in other organism",
- "xrefs" : [ "GOC:mah" ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "cell organization and biogenesis",
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- "val" : "GO:0071842"
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- "type" : "PROPERTY",
- "lbl" : "term replaced by"
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- "id" : "http://purl.obolibrary.org/obo/GO_0000279",
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- "definition" : {
- "val" : "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.",
- "xrefs" : [ "GOC:mtg_cell_cycle" ]
- },
- "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ],
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- "val" : "Wikipedia:M_phase"
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- "definition" : {
- "val" : "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.",
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- },
- "comments" : [ "Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle." ],
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- "val" : "Wikipedia:Mitosis"
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- "val" : "GO:0007067"
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- "definition" : {
- "val" : "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.",
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway."
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- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of or within"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007078",
- "meta" : {
- "definition" : {
- "val" : "3rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 830." ],
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- "id" : "http://purl.obolibrary.org/obo/RO_0002385",
- "meta" : {
- "definition" : {
- "val" : "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y",
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- "type" : "PROPERTY",
- "lbl" : "has potential to developmentally contribute to"
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- "id" : "http://purl.obolibrary.org/obo/RO_0002022",
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- "comments" : [ "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007077",
- "meta" : {
- "definition" : {
- "val" : "2nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 820." ],
- "basicPropertyValues" : [ {
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- "definition" : {
- "val" : "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.",
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- "definition" : {
- "val" : "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.",
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- "id" : "http://purl.obolibrary.org/obo/RO_0002387",
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- "definition" : {
- "val" : "x has the potential to develop into y iff x develops into y or if x is capable of developing into y",
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- "val" : "Chris Mungall"
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- "type" : "PROPERTY",
- "lbl" : "has potential to develop into"
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- "meta" : {
- "definition" : {
- "val" : "1st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 810." ],
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- "type" : "PROPERTY",
- "lbl" : "has potential to directly develop into"
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- "id" : "http://purl.obolibrary.org/obo/RO_0002025",
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- "definition" : {
- "val" : "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.",
- "xrefs" : [ "GOC:dos" ]
- },
- "comments" : [ "This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations." ],
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- "meta" : {
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- "val" : "The day of eclosion.",
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- },
- "comments" : [ "Temporal ordering number - 780." ],
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- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 360." ],
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- },
- "comments" : [ "Temporal ordering number - 370." ],
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- "val" : "Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 350." ],
- "synonyms" : [ {
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- "val" : "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).",
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- "type" : "PROPERTY",
- "lbl" : "has developmental potential involving"
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- "meta" : {
- "definition" : {
- "val" : "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.",
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- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
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- "type" : "PROPERTY",
- "lbl" : "acts upstream of"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007079",
- "meta" : {
- "definition" : {
- "val" : "4th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 840." ],
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 4 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005331",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 13-15.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 330." ],
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- "type" : "CLASS",
- "lbl" : "dorsal closure stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005325",
- "meta" : {
- "definition" : {
- "val" : "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 310." ],
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- "type" : "CLASS",
- "lbl" : "embryonic stage 11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005326",
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- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "contracted germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005323",
- "meta" : {
- "definition" : {
- "val" : "Stage 9 begins when mesodermal segmentation becomes (transiently) visible\\, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 280." ],
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- "type" : "CLASS",
- "lbl" : "embryonic stage 9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005324",
- "meta" : {
- "definition" : {
- "val" : "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 290." ],
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- "type" : "CLASS",
- "lbl" : "embryonic stage 10"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005329",
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- "val" : "FBdv:00005330"
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- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "head involution stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002015",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.",
- "xrefs" : [ ]
- },
- "comments" : [ "By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'." ],
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- "val" : "2017-05-24T09:31:17Z"
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- "val" : "dos"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has positive regulatory component activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002258",
- "meta" : {
- "definition" : {
- "val" : "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p",
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- },
- "comments" : [ "This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from" ],
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "false"
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- "val" : "In general you should not use this relation to make assertions - use one of the more specific relations below this one"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
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- "val" : "Chris Mungall"
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- },
- "type" : "PROPERTY",
- "lbl" : "developmentally preceded by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005327",
- "meta" : {
- "definition" : {
- "val" : "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 320." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "retracting germ band stage",
- "xrefs" : [ ]
- } ],
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- "lbl" : "embryonic stage 12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002017",
- "meta" : {
- "comments" : [ "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ],
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- "val" : "2017-05-24T09:44:33Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has component activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002018",
- "meta" : {
- "definition" : {
- "val" : "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
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- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has component process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005328",
- "meta" : {
- "definition" : {
- "val" : "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 340." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
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- } ],
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- },
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- "lbl" : "embryonic stage 13"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "type" : "PROPERTY",
- "lbl" : "has_alternative_id"
- }, {
- "id" : "http://purl.obolibrary.org/obo/CARO_0000000",
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- },
- "type" : "CLASS",
- "lbl" : "anatomical entity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0098763",
- "meta" : {
- "definition" : {
- "val" : "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.",
- "xrefs" : [ "GOC:dos" ]
- },
- "comments" : [ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ],
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- "type" : "CLASS",
- "lbl" : "mitotic cell cycle phase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0011002",
- "meta" : {
- "definition" : {
- "val" : "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
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- },
- "type" : "PROPERTY",
- "lbl" : "regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007023",
- "meta" : {
- "definition" : {
- "val" : "The M-phase (GO:0000279) of an embryonic cycle.",
- "xrefs" : [ "FBC:DOS" ]
- },
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- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle M-phase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002254",
- "meta" : {
- "definition" : {
- "val" : "x has developmental contribution from y iff x has some part z such that z develops from y",
- "xrefs" : [ ]
- },
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has developmental contribution from"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002012",
- "meta" : {
- "definition" : {
- "val" : "A part of relation that applies only between occurents.",
- "xrefs" : [ ]
- },
- "xrefs" : [ {
- "val" : "RO:0002012"
- } ],
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- },
- "type" : "PROPERTY",
- "lbl" : "occurent part of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007022",
- "meta" : {
- "definition" : {
- "val" : "The interphase (GO:0051325) of an embryonic cycle.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
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- },
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- "lbl" : "embryonic cycle interphase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002013",
- "meta" : {
- "definition" : {
- "val" : "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.",
- "xrefs" : [ ]
- },
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- "type" : "PROPERTY",
- "lbl" : "has regulatory component activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002255",
- "meta" : {
- "definition" : {
- "val" : "inverse of has developmental contribution from",
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- },
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- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
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- },
- "type" : "PROPERTY",
- "lbl" : "developmentally contributes to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007021",
- "meta" : {
- "definition" : {
- "val" : "The substage of the wandering third instar larval stage when the larva has cleared its gut contents.",
- "xrefs" : [ "FlyBase:FBrf0076598" ]
- },
- "comments" : [ "Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994." ],
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- "lbl" : "third instar - cleared gut stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007020",
- "meta" : {
- "definition" : {
- "val" : "The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.",
- "xrefs" : [ "FlyBase:FBrf0076598" ]
- },
- "comments" : [ "Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994)." ],
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- "lbl" : "third instar - partially cleared gut stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002014",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.",
- "xrefs" : [ ]
- },
- "comments" : [ "By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'." ],
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- "type" : "PROPERTY",
- "lbl" : "has negative regulatory component activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007026",
- "meta" : {
- "definition" : {
- "val" : "Life stage from the end of adult stage A3, when tanning is complete, to death.",
- "xrefs" : [ "FBC:DOS" ]
- },
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- },
- "type" : "CLASS",
- "lbl" : "mature adult stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007025",
- "meta" : {
- "definition" : {
- "val" : "The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 782." ],
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- "meta" : {
- "definition" : {
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- "lbl" : "biological process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007019",
- "meta" : {
- "definition" : {
- "val" : "The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.",
- "xrefs" : [ "FlyBase:FBrf0076598" ]
- },
- "comments" : [ "Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994)." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007018",
- "meta" : {
- "definition" : {
- "val" : "Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).",
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- "val" : "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).",
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- "comments" : [ "Temporal ordering number - 10250." ],
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- "val" : "david"
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- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13E"
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- "id" : "http://purl.obolibrary.org/obo/RO_0000057",
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- },
- "basicPropertyValues" : [ {
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this blood coagulation has participant this blood clot"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007127",
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- "val" : "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.",
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- "id" : "http://purl.obolibrary.org/obo/GO_0009987",
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- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_plant" ],
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- "pred" : "hasExactSynonym",
- "val" : "cell physiology",
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- }, {
- "pred" : "hasNarrowSynonym",
- "val" : "cell growth and/or maintenance",
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- "pred" : "hasRelatedSynonym",
- "val" : "single-organism cellular process",
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- "val" : "GO:0044763"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "GO:0008151"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
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- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Hill"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000600",
- "val" : "false"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Tanya Berardini"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "regulates (processual)"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "regulates"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002212",
- "meta" : {
- "definition" : {
- "val" : "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "negatively regulates (process to process)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
- "val" : "http://purl.obolibrary.org/obo/RO_0002211"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "negatively regulates"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002333",
- "meta" : {
- "definition" : {
- "val" : "inverse of enables",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "enabled by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005283",
- "meta" : {
- "definition" : {
- "val" : "The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10260." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005288",
- "meta" : {
- "comments" : [ "Temporal ordering number - 10." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "fertilized egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007104",
- "meta" : {
- "definition" : {
- "val" : "29th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1090." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 29 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005289",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from fertilization to hatching.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 20." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007103",
- "meta" : {
- "definition" : {
- "val" : "28th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1080." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 28 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007102",
- "meta" : {
- "definition" : {
- "val" : "27th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1070." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 27 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00006012",
- "meta" : {
- "definition" : {
- "val" : "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 800." ],
- "synonyms" : [ {
- "pred" : "hasRelatedSynonym",
- "val" : "adult stage III",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "FBdv:00005375"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "adult stage A3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005286",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.",
- "xrefs" : [ "FlyBase:FBrf0064779" ]
- },
- "comments" : [ "Temporal ordering number - 10290." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002450",
- "meta" : {
- "definition" : {
- "val" : "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.",
- "xrefs" : [ ]
- },
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "molecularly increases activity of",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "directly activates"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "directly positively regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005287",
- "meta" : {
- "comments" : [ "Temporal ordering number - 10300." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "unfertilized egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007101",
- "meta" : {
- "definition" : {
- "val" : "26th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1060." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 26 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002448",
- "meta" : {
- "definition" : {
- "val" : "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.",
- "xrefs" : [ ]
- },
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "molecularly controls",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "directly regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002327",
- "meta" : {
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "executes"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "catalyzes"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "a particular instances of akt-2 enables some instance of protein kinase activity"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "is catalyzing"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "is executing"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "has"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "enables"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002449",
- "meta" : {
- "definition" : {
- "val" : "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.",
- "xrefs" : [ ]
- },
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "molecularly decreases activity of",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "directly inhibits"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "directly negatively regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002328",
- "meta" : {
- "definition" : {
- "val" : "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "This is a grouping relation that collects relations used for the purpose of connecting structure and function"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "functionally related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002329",
- "meta" : {
- "definition" : {
- "val" : "this relation holds between c and p when c is part of some c', and c' is capable of p.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "false"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "part of structure that is capable of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005279",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000050",
- "meta" : {
- "definition" : {
- "val" : "a core relation that holds between a part and its whole",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
- "xrefs" : [ {
- "val" : "BFO:0000050"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "part_of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000004"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000003"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000002"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://www.obofoundry.org/ro/#OBO_REL:part_of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my brain is part of my body (continuant parthood, two material entities)"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000020"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000017"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000019"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "is part of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this day is part of this year (occurrent parthood)"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://ontologydesignpatterns.org/wiki/Submissions:PartOf"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000031"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "part_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "part of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002323",
- "meta" : {
- "definition" : {
- "val" : "A mereological relationship or a topological relationship",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "mereotopologically related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002202",
- "meta" : {
- "definition" : {
- "val" : "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y",
- "xrefs" : [ ]
- },
- "comments" : [ "This is the transitive form of the develops from relation" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Terry Meehan"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Melissa Haendel"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "develops from"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002203",
- "meta" : {
- "definition" : {
- "val" : "inverse of develops from",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Terry Meehan"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "develops into"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002566",
- "meta" : {
- "definition" : {
- "val" : "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "causally influences (entity-centric)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "causally influences"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002324",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between entities participating in some developmental process (GO:0032502)",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "developmentally related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002447",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Axiomatization to GO to be added later"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y."
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "phosphorylates"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00018001",
- "meta" : {
- "comments" : [ "Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO." ],
- "xrefs" : [ {
- "val" : "FBdv:00018001"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "substage_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "substage_of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/IAO_0000115",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "definition"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000051",
- "meta" : {
- "definition" : {
- "val" : "a core relation that holds between a whole and its part",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
- "xrefs" : [ {
- "val" : "OBO_REL:has_part"
- }, {
- "val" : "BFO:0000051"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "has_part"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "has_part"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "has part"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this year has part this day (occurrent parthood)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my body has part my brain (continuant parthood, two material entities)"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has_part"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005270",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10100." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005273",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0043885", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10130." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005274",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0043885", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10160." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005271",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074" ]
- },
- "comments" : [ "Temporal ordering number - 10110." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002563",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://xmlns.com/foaf/0.1/page",
- "val" : "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "interaction relation helper property"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002564",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "molecular interaction relation helper property"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005272",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10120." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005277",
- "meta" : {
- "definition" : {
- "val" : "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.",
- "xrefs" : [ "FlyBase:FBrf0021038" ]
- },
- "comments" : [ "Temporal ordering number - 10190." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12C"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005278",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0029744", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10200." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005275",
- "meta" : {
- "definition" : {
- "val" : "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10170." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005276",
- "meta" : {
- "definition" : {
- "val" : "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10180." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002559",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "causally influenced by (entity-centric)"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "causally influenced by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005268",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10080." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005269",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10090." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002434",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between two entities in which the processes executed by the two entities are causally connected.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "in pairwise interaction with",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://purl.obolibrary.org/obo/MI_0914"
- }, {
- "pred" : "http://xmlns.com/foaf/0.1/page",
- "val" : "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Considering relabeling as 'pairwise interacts with'"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "interacts with"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002314",
- "meta" : {
- "definition" : {
- "val" : "q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "https://github.com/oborel/obo-relations/wiki/ROGuide#defining-property-chains-involving-reflexivity"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Because part_of is transitive, inheres in is a sub-relation of inheres in part of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "inheres in part of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002436",
- "meta" : {
- "definition" : {
- "val" : "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "molecularly binds with"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "binds"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://purl.obolibrary.org/obo/ECO_0000353"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://purl.obolibrary.org/obo/MI_0915"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "molecularly interacts with"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000040",
- "meta" : {
- "definition" : {
- "val" : "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.",
- "xrefs" : [ ]
+ ],
+ "equivalentNodesSets": [],
+ "id": "http://purl.obolibrary.org/obo/fbdv/fbdv-non-classified.json",
+ "logicalDefinitionAxioms": [
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/FBdv_00007022",
+ "genusIds": [
+ "http://purl.obolibrary.org/obo/GO_0051325"
+ ],
+ "restrictions": [
+ {
+ "fillerId": "http://purl.obolibrary.org/obo/FBdv_00007011",
+ "propertyId": "http://purl.obolibrary.org/obo/FBdv_00018001"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/FBdv_00007023",
+ "genusIds": [
+ "http://purl.obolibrary.org/obo/GO_0000279"
+ ],
+ "restrictions": [
+ {
+ "fillerId": "http://purl.obolibrary.org/obo/FBdv_00007011",
+ "propertyId": "http://purl.obolibrary.org/obo/FBdv_00018001"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/GO_0000087",
+ "genusIds": [
+ "http://purl.obolibrary.org/obo/GO_0000279"
+ ],
+ "restrictions": [
+ {
+ "fillerId": "http://purl.obolibrary.org/obo/GO_0000278",
+ "propertyId": "http://purl.obolibrary.org/obo/RO_0002092"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/GO_0000278",
+ "genusIds": [
+ "http://purl.obolibrary.org/obo/GO_0007049"
+ ],
+ "restrictions": [
+ {
+ "fillerId": "http://purl.obolibrary.org/obo/GO_0140014",
+ "propertyId": "http://purl.obolibrary.org/obo/BFO_0000051"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/GO_0022402",
+ "genusIds": [
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- },
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- "comments" : [ "Temporal ordering number - 70." ],
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- "val" : "The seventh mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- },
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- "val" : "The fifth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
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- "comments" : [ "Temporal ordering number - 1120." ],
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- "comments" : [ "Temporal ordering number - 1110." ],
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- "meta" : {
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- "type" : "PROPERTY",
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- },
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- "comments" : [ "Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant" ],
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- "type" : "PROPERTY",
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- },
- "comments" : [ "Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant" ],
- "basicPropertyValues" : [ {
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- "val" : "site of"
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- },
- "type" : "PROPERTY",
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- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
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- "val" : "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "is preceded by"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "preceded by"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "preceded_by"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "preceded_by"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "preceded_by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0003824",
- "type" : "CLASS",
- "lbl" : "catalytic activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000063",
- "meta" : {
- "definition" : {
- "val" : "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "precedes"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "precedes"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002091",
- "meta" : {
- "comments" : [ "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
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- "val" : "io"
- }, {
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- "val" : "David Osumi-Sutherland"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "starts during"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule",
- "type" : "PROPERTY",
- "lbl" : "namespace-id-rule"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002092",
- "meta" : {
- "comments" : [ "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
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- "val" : "during"
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- "val" : "external"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "happens during"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002093",
- "meta" : {
- "comments" : [ "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). " ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "xrefs" : [ {
- "val" : "RO:0002093"
- } ],
- "basicPropertyValues" : [ {
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- "val" : "ends_during"
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- "val" : "o"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "overlaps"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "ends during"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0000087",
- "meta" : {
- "definition" : {
- "val" : "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.",
- "xrefs" : [ "GOC:mtg_cell_cycle" ]
- },
- "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "M phase of mitotic cell cycle",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "M-phase of mitotic cell cycle",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "mitotic M phase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000015",
- "meta" : {
- "definition" : {
- "val" : "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.",
- "xrefs" : [ ]
- }
- },
- "type" : "CLASS",
- "lbl" : "process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002090",
- "meta" : {
- "comments" : [ "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "xrefs" : [ {
- "val" : "RO:0002090"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "ends_at_start_of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "meets"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0002575",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000063"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "ends_at_start_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "ends_at_start_of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005361",
- "meta" : {
- "definition" : {
- "val" : "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 690." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004035",
- "meta" : {
- "definition" : {
- "val" : "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2018-01-26T23:53:22Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "cjm"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
- "val" : "http://purl.obolibrary.org/obo/RO_0002263"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of,_negative_effect"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of, negative effect"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005362",
- "meta" : {
- "definition" : {
- "val" : "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 700." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "wing tips grey stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12(i)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P12(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002410",
- "meta" : {
- "definition" : {
- "val" : "This relation groups causal relations between material entities and causal relations between processes",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types."
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "causally related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005360",
- "meta" : {
- "definition" : {
- "val" : "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 680." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "thoracic bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11(ii)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- } ]
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- "lbl" : "pharate adult stage P11(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005365",
- "meta" : {
- "definition" : {
- "val" : "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 730." ],
- "synonyms" : [ {
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- "val" : "pupal stage P14",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "mature bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
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- } ]
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- "type" : "CLASS",
- "lbl" : "pharate adult stage P14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004032",
- "meta" : {
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "cjm"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
- "val" : "http://purl.obolibrary.org/obo/RO_0002264"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2018-01-26T23:49:30Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of or within, positive effect"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0007275",
- "meta" : {
- "definition" : {
- "val" : "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",
- "xrefs" : [ "GOC:dph", "GOC:ems", "GOC:isa_complete", "GOC:tb" ]
- },
- "comments" : [ "Note that this term was 'developmental process'." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_plant" ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "multicellular organism development"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005366",
- "meta" : {
- "definition" : {
- "val" : "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 740." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P15",
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- } ],
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- } ]
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- "type" : "CLASS",
- "lbl" : "pharate adult stage P15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004031",
- "meta" : {
- "definition" : {
- "val" : "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.",
- "xrefs" : [ ]
- },
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- "val" : "cjm"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "enables subfunction"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004034",
- "meta" : {
- "definition" : {
- "val" : "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
- "val" : "http://purl.obolibrary.org/obo/RO_0002263"
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- "val" : "cjm"
- }, {
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- "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of,_positive_effect"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2018-01-26T23:53:14Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of, positive effect"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005363",
- "meta" : {
- "definition" : {
- "val" : "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 710." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12(ii)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "wings grey stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P12(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005364",
- "meta" : {
- "definition" : {
- "val" : "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 720." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P13",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "wings black stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004033",
- "meta" : {
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- "val" : "cjm"
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- "val" : "2018-01-26T23:49:51Z"
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- "type" : "PROPERTY",
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- "id" : "http://purl.obolibrary.org/obo/RO_0002404",
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- "val" : "Chris Mungall"
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- },
- "type" : "PROPERTY",
- "lbl" : "causally downstream of"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005358",
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- "val" : "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 660." ],
- "synonyms" : [ {
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- "val" : "pupal stage P11",
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- "basicPropertyValues" : [ {
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- "lbl" : "pharate adult stage P11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005359",
- "meta" : {
- "definition" : {
- "val" : "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 670." ],
- "synonyms" : [ {
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- "val" : "pupal stage P11(i)",
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- }, {
- "pred" : "hasExactSynonym",
- "val" : "head bristles stage",
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- "basicPropertyValues" : [ {
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- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
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- },
- "type" : "PROPERTY",
- "lbl" : "immediately causally downstream of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005356",
- "meta" : {
- "definition" : {
- "val" : "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
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- "comments" : [ "Temporal ordering number - 640." ],
- "synonyms" : [ {
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- "val" : "amber-eyed stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P9",
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- "lbl" : "pharate adult stage P9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005357",
- "meta" : {
- "definition" : {
- "val" : "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 650." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P10",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "red-eye bald stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
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- "id" : "http://purl.obolibrary.org/obo/GO_0016301",
- "type" : "CLASS",
- "lbl" : "kinase activity"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_root_00000000",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0100001",
- "val" : "http://purl.obolibrary.org/obo/FBdv_00000000"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000231",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000227"
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- "deprecated" : true
- },
- "type" : "CLASS"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007092",
- "meta" : {
- "definition" : {
- "val" : "17th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 970." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- },
- "type" : "CLASS",
- "lbl" : "day 17 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007091",
- "meta" : {
- "definition" : {
- "val" : "16th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 960." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- },
- "type" : "CLASS",
- "lbl" : "day 16 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007090",
- "meta" : {
- "definition" : {
- "val" : "15th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 950." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 15 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007096",
- "meta" : {
- "definition" : {
- "val" : "21st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1010." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 21 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000004",
- "meta" : {
- "definition" : {
- "val" : "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.",
- "xrefs" : [ ]
- }
- },
- "type" : "CLASS",
- "lbl" : "independent continuant"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007095",
- "meta" : {
- "definition" : {
- "val" : "20th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1000." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 20 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007094",
- "meta" : {
- "definition" : {
- "val" : "19th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 990." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 19 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0006996",
- "meta" : {
- "definition" : {
- "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.",
- "xrefs" : [ "GOC:mah" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_aspergillus" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "single organism organelle organization",
- "xrefs" : [ "GOC:TermGenie" ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "organelle organization and biogenesis",
- "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:mah" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "organelle organisation",
- "xrefs" : [ ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "single-organism organelle organization",
- "xrefs" : [ ]
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- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "GO:1902589"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "jl"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2013-12-19T15:25:51Z"
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- },
- "type" : "CLASS",
- "lbl" : "organelle organization"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007093",
- "meta" : {
- "definition" : {
- "val" : "18th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 980." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 18 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0007049",
- "meta" : {
- "definition" : {
- "val" : "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.",
- "xrefs" : [ "GOC:go_curators", "GOC:mtg_cell_cycle" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_aspergillus", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl" ],
- "xrefs" : [ {
- "val" : "Wikipedia:Cell_cycle"
- } ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "cell-division cycle",
- "xrefs" : [ ]
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- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "type" : "CLASS",
- "lbl" : "cell cycle"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005350",
- "meta" : {
- "definition" : {
- "val" : "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
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- "comments" : [ "Temporal ordering number - 580." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "pupal stage P5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002088",
- "meta" : {
- "comments" : [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
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- "val" : "David Osumi-Sutherland"
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- },
- "type" : "PROPERTY",
- "lbl" : "during which starts"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005351",
- "meta" : {
- "definition" : {
- "val" : "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 590." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "Malpighian tubules migrating",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
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- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007099",
- "meta" : {
- "definition" : {
- "val" : "24th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1040." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 24 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007098",
- "meta" : {
- "definition" : {
- "val" : "23rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1030." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- },
- "type" : "CLASS",
- "lbl" : "day 23 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007097",
- "meta" : {
- "definition" : {
- "val" : "22nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1020." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 22 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002084",
- "meta" : {
- "comments" : [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
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- "val" : "David Osumi-Sutherland"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "during which ends"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005354",
- "meta" : {
- "definition" : {
- "val" : "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 620." ],
- "synonyms" : [ {
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- "val" : "yellow body stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002085",
- "meta" : {
- "comments" : [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ],
- "basicPropertyValues" : [ {
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- "val" : "David Osumi-Sutherland"
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- "val" : "di"
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- },
- "type" : "PROPERTY",
- "lbl" : "encompasses"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005355",
- "meta" : {
- "definition" : {
- "val" : "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 630." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "yellow-eyed stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P8",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005352",
- "meta" : {
- "definition" : {
- "val" : "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 600." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "white Malpighian tubules stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002086",
- "meta" : {
- "comments" : [ "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- } ]
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- "type" : "PROPERTY",
- "lbl" : "ends after"
- }, {
- "id" : "http://purl.obolibrary.org/obo/fbdv#systematic_synonym",
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- },
- "type" : "PROPERTY",
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- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002087",
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- "comments" : [ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" ],
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- "val" : "RO:0002087"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "val" : "immediately_preceded_by"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "starts_at_end_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "immediately_preceded_by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005353",
- "meta" : {
- "definition" : {
- "val" : "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 610." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "green Malpighian tubules stage",
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- } ],
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P6"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005347",
- "meta" : {
- "definition" : {
- "val" : "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 550." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P4(i)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "buoyant stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P4(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005348",
- "meta" : {
- "definition" : {
- "val" : "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 560." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "moving bubble stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P4(ii)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P4(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005345",
- "meta" : {
- "definition" : {
- "val" : "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 530." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "bubble prepupa stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P3",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005346",
- "meta" : {
- "definition" : {
- "val" : "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 540." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "cryptocephalic pupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P4",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P4"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0140014",
- "meta" : {
- "definition" : {
- "val" : "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",
- "xrefs" : [ "ISBN:0198547684" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "mitosis",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000233",
- "val" : "https://github.com/geneontology/go-ontology/issues/19910"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2017-03-23T14:44:23Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "pg"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "mitotic nuclear division"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005349",
- "meta" : {
- "definition" : {
- "val" : "The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 570. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for Cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head and expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "phanerocephalic pupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym",
- "type" : "PROPERTY",
- "lbl" : "has_broad_synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000002",
- "meta" : {
- "definition" : {
- "val" : "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.",
- "xrefs" : [ ]
+ ],
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00000000"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00005259"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00007013"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00007024"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/creator",
+ "val": "http://orcid.org/0000-0002-1373-1705"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/creator",
+ "val": "http://orcid.org/0000-0002-7073-9172"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/creator",
+ "val": "https://orcid.org/0000-0001-5948-3092"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/creator",
+ "val": "https://orcid.org/0000-0002-0027-0858"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/description",
+ "val": "An ontology of Drosophila melanogaster developmental stages."
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/title",
+ "val": "FlyBase Developmental Ontology (FBdv)"
+ },
+ {
+ "pred": "http://purl.org/dc/terms/license",
+ "val": "https://creativecommons.org/licenses/by/3.0/"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule",
+ "val": "* FBdv:$sequence(8,7000,10000)$"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#date",
+ "val": "10:03:2021 10:38"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#default-namespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion",
+ "val": "1.2"
+ },
+ {
+ "pred": "http://www.w3.org/2002/07/owl#versionInfo",
+ "val": "2021-03-10"
+ }
+ ],
+ "subsets": [],
+ "version": "http://purl.obolibrary.org/obo/fbdv/releases/2021-03-10/fbdv-non-classified.json",
+ "xrefs": []
+ },
+ "nodes": [
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000002",
+ "lbl": "continuant",
+ "meta": {
+ "definition": {
+ "val": "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000003",
+ "lbl": "occurrent",
+ "meta": {
+ "definition": {
+ "val": "An entity that has temporal parts and that happens, unfolds or develops through time.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000004",
+ "lbl": "independent continuant",
+ "meta": {
+ "definition": {
+ "val": "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000015",
+ "lbl": "process",
+ "meta": {
+ "definition": {
+ "val": "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000020",
+ "lbl": "specifically dependent continuant",
+ "meta": {
+ "definition": {
+ "val": "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000040",
+ "lbl": "material entity",
+ "meta": {
+ "definition": {
+ "val": "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000050",
+ "lbl": "part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "is part of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my brain is part of my body (continuant parthood, two material entities)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this day is part of this year (occurrent parthood)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "part_of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000002"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000003"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000004"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000017"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000019"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000020"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000031"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "part_of"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Submissions:PartOf"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://www.obofoundry.org/ro/#OBO_REL:part_of"
+ }
+ ],
+ "definition": {
+ "val": "a core relation that holds between a part and its whole",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000050"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000051",
+ "lbl": "has_part",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "has part"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my body has part my brain (continuant parthood, two material entities)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this year has part this day (occurrent parthood)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has_part"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "has_part"
+ }
+ ],
+ "definition": {
+ "val": "a core relation that holds between a whole and its part",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000051"
+ },
+ {
+ "val": "OBO_REL:has_part"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000062",
+ "lbl": "preceded_by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "preceded by"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "is preceded by"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "preceded_by"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/source",
+ "val": "http://www.obofoundry.org/ro/#OBO_REL:preceded_by"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "preceded_by"
+ }
+ ],
+ "definition": {
+ "val": "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000062"
+ },
+ {
+ "val": "OBO_REL:preceded_by"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000063",
+ "lbl": "precedes",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "precedes"
+ }
+ ],
+ "definition": {
+ "val": "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000066",
+ "lbl": "occurs in",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "occurs in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "occurs_in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "unfolds in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "unfolds_in"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
+ "val": "http://purl.obolibrary.org/obo/bfo.owl"
+ }
+ ],
+ "comments": [
+ "Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant"
+ ],
+ "definition": {
+ "val": "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000067",
+ "lbl": "contains process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "site of"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
+ "val": "http://purl.obolibrary.org/obo/bfo.owl"
+ }
+ ],
+ "comments": [
+ "Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant"
+ ],
+ "definition": {
+ "val": "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/CARO_0000000",
+ "lbl": "anatomical entity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000412",
+ "val": "http://purl.obolibrary.org/obo/caro.owl"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00000000",
+ "lbl": "Drosophila life",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv_root:00000000"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The life of an individual of the species Drosophila melanogaster, from fertilization to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "Drosophila life cycle",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00000054",
+ "lbl": "cleavage stage",
+ "meta": {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 25."
+ ],
+ "definition": {
+ "val": "A collective term for stages 1-4.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00004450",
+ "lbl": "late extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 300."
+ ],
+ "definition": {
+ "val": "A collective term for stages 11 and 12.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00004886",
+ "lbl": "oogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10000."
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "oogenesis stage",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0048477"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005259",
+ "lbl": "developmental stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:56:56Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00007010"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A temporal subdivision of a developmental process.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005261",
+ "lbl": "oogenesis stage S1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10010."
+ ],
+ "definition": {
+ "val": "Earliest stage of ovarian cyst development - lasts while the 16 cell cyst is within the germarium (region 3).",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005262",
+ "lbl": "oogenesis stage S2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10020."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the cyst leaves the germarium (from this point the cyst is referred to as an egg chamber). During this stage, polyploidation of the nurse cells begins, they reach a ploidy of 8C, and follicle cells start to divide.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005263",
+ "lbl": "oogenesis stage S3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10030."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the oocyte chromosomes condense into a karyosome attached to a distinctive spherical structure known as an endobody. The oocyte nucleolus disappears completely. During this stage, nurse cell ploidy reaches 16C.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005264",
+ "lbl": "oogenesis stage S4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10040."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the nurse cells chromosomes become bulbous. Nurse cell chromosomes during this stage are polytene and reach a ploidy of 32C. The egg chamber is oval shaped.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005265",
+ "lbl": "oogenesis stage S5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10050."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell chromosomes are no longer bulbous - the association between homologs weakens so that these chromosomes no longer have a polytene structure. During this stage, posterior nurse cell nuclei have a higher ploidy (64C) than anterior ones.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005266",
+ "lbl": "oogenesis stage S6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10060."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which follicle cell division ceases.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005267",
+ "lbl": "oogenesis stage S7",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10070."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which polyploidation and enlargement of follicle cells begins. Nurse cell ploidy ranges from 256C (anterior) to 512C (posterior) and the egg chamber gains an elongated shape.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005268",
+ "lbl": "oogenesis stage S8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10080."
+ ],
+ "definition": {
+ "val": "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005269",
+ "lbl": "oogenesis stage S9",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10090."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.",
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+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005270",
+ "lbl": "oogenesis stage S10",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10100."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005271",
+ "lbl": "oogenesis stage S10A",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10110."
+ ],
+ "definition": {
+ "val": "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005272",
+ "lbl": "oogenesis stage S10B",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10120."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005273",
+ "lbl": "oogenesis stage S11",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10130."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0043885",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005274",
+ "lbl": "oogenesis stage S12",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10160."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0043885",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005275",
+ "lbl": "oogenesis stage S12A",
+ "meta": {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10170."
+ ],
+ "definition": {
+ "val": "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005276",
+ "lbl": "oogenesis stage S12B",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10180."
+ ],
+ "definition": {
+ "val": "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005277",
+ "lbl": "oogenesis stage S12C",
+ "meta": {
+ "basicPropertyValues": [
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+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10190."
+ ],
+ "definition": {
+ "val": "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.",
+ "xrefs": [
+ "FlyBase:FBrf0021038"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005278",
+ "lbl": "oogenesis stage S13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10200."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0029744",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005279",
+ "lbl": "oogenesis stage S13A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005280",
+ "lbl": "oogenesis stage S13B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10220. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which 9-11 nurse cell nuclei remain at the anterior of the oocyte. During this stage, the nuclear membrane of the oocyte nucleus disappears, indicating the start of meiotic pro-metaphase.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005281",
+ "lbl": "oogenesis stage S13C",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10230."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which only 7-8 nurse cell nuclei remain at the anterior of the oocyte. At the beginning of this stage, oocyte chromosome bivalents separate from each other - indicating mid-prometaphase of oocyte meiosis.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005282",
+ "lbl": "oogenesis stage S13D",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10240."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005283",
+ "lbl": "oogenesis stage S14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10260."
+ ],
+ "definition": {
+ "val": "The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005284",
+ "lbl": "oogenesis stage S14A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10270."
+ ],
+ "definition": {
+ "val": "Secretion and formation of the outer endochorionic network by throughout the follicle. Crystallization of the innermost chorionic layer of the main body follicle cells.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005285",
+ "lbl": "oogenesis stage S14B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10280."
+ ],
+ "definition": {
+ "val": "Secretion of the exochorion begins and ends.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005286",
+ "lbl": "egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10290."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.",
+ "xrefs": [
+ "FlyBase:FBrf0064779"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005287",
+ "lbl": "unfertilized egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10300."
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005288",
+ "lbl": "fertilized egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10."
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005289",
+ "lbl": "embryonic stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 20."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from fertilization to hatching.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005290",
+ "lbl": "pre-blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 30."
+ ],
+ "definition": {
+ "val": "Embryonic stage 1-3.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pre-blastoderm",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005291",
+ "lbl": "embryonic stage 1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 40."
+ ],
+ "definition": {
+ "val": "The embryonic stage that lasts from the end of fertilization to the end of the second nuclear division. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0064779",
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005292",
+ "lbl": "embryonic cycle 1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 50."
+ ],
+ "definition": {
+ "val": "The first mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005293",
+ "lbl": "embryonic stage 2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 70."
+ ],
+ "definition": {
+ "val": "Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005294",
+ "lbl": "embryonic cycle 2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 60."
+ ],
+ "definition": {
+ "val": "The second mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005295",
+ "lbl": "embryonic cycle 3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 80."
+ ],
+ "definition": {
+ "val": "The third mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005296",
+ "lbl": "embryonic cycle 4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 90."
+ ],
+ "definition": {
+ "val": "The fourth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005297",
+ "lbl": "embryonic cycle 5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 100."
+ ],
+ "definition": {
+ "val": "The fifth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005298",
+ "lbl": "embryonic cycle 6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 110."
+ ],
+ "definition": {
+ "val": "The sixth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005299",
+ "lbl": "embryonic cycle 7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 120."
+ ],
+ "definition": {
+ "val": "The seventh mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005300",
+ "lbl": "embryonic cycle 8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 130."
+ ],
+ "definition": {
+ "val": "The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005301",
+ "lbl": "embryonic stage 3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 140."
+ ],
+ "definition": {
+ "val": "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005302",
+ "lbl": "embryonic cycle 9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 150."
+ ],
+ "definition": {
+ "val": "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005303",
+ "lbl": "embryonic cycle 10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 180."
+ ],
+ "definition": {
+ "val": "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005304",
+ "lbl": "blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 160."
+ ],
+ "definition": {
+ "val": "Embryonic stages 4 and 5.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "blastoderm",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005305",
+ "lbl": "syncytial blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005306",
+ "lbl": "embryonic stage 4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 170."
+ ],
+ "definition": {
+ "val": "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "syncytial blastoderm",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "syncytial blastoderm stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005307",
+ "lbl": "embryonic cycle 11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 185."
+ ],
+ "definition": {
+ "val": "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005308",
+ "lbl": "embryonic cycle 12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 190."
+ ],
+ "definition": {
+ "val": "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005309",
+ "lbl": "embryonic cycle 13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 200."
+ ],
+ "definition": {
+ "val": "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005310",
+ "lbl": "cellular blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005311",
+ "lbl": "embryonic stage 5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 210."
+ ],
+ "definition": {
+ "val": "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular blastoderm",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular blastoderm stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005312",
+ "lbl": "embryonic cycle 14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "FlyBase:FBrf0049535",
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "first blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005313",
+ "lbl": "embryonic cycle 14A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 256."
+ ],
+ "definition": {
+ "val": "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "[FlyBase:FBrf0039741"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonic cycle 14 interphase",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005314",
+ "lbl": "embryonic cycle 14B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "FlyBase:FBrf0039741"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonic cycle 14 M-phase",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005315",
+ "lbl": "embryonic cycle 15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 15th cell cycle of embryogenesis. Asynchronous.",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "second blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005316",
+ "lbl": "embryonic cycle 16",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 16th cell cycle division of embryogenesis. Asynchronous.",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "third blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005317",
+ "lbl": "gastrula stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 220."
+ ],
+ "definition": {
+ "val": "Stages during which gastrulation occurs. 6-8.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "gastrula",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005318",
+ "lbl": "embryonic stage 6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 230."
+ ],
+ "definition": {
+ "val": "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005319",
+ "lbl": "embryonic stage 7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 240."
+ ],
+ "definition": {
+ "val": "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005320",
+ "lbl": "germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005321",
+ "lbl": "extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 260."
+ ],
+ "definition": {
+ "val": "Stages during which the germ band is extended - 9-12.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005322",
+ "lbl": "embryonic stage 8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 250."
+ ],
+ "definition": {
+ "val": "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "rapidly extending germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005323",
+ "lbl": "embryonic stage 9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 280."
+ ],
+ "definition": {
+ "val": "Stage 9 begins when mesodermal segmentation becomes (transiently) visible\\, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005324",
+ "lbl": "embryonic stage 10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 290."
+ ],
+ "definition": {
+ "val": "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005325",
+ "lbl": "embryonic stage 11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 310."
+ ],
+ "definition": {
+ "val": "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005326",
+ "lbl": "contracted germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005327",
+ "lbl": "embryonic stage 12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 320."
+ ],
+ "definition": {
+ "val": "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "retracting germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005328",
+ "lbl": "embryonic stage 13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 340."
+ ],
+ "definition": {
+ "val": "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "contracted germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005329",
+ "lbl": "head involution stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "FBdv:00005330"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005330",
+ "lbl": "embryonic stage 14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 350."
+ ],
+ "definition": {
+ "val": "Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "head involution stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005331",
+ "lbl": "dorsal closure stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 330."
+ ],
+ "definition": {
+ "val": "A collective term for stages 13-15.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005332",
+ "lbl": "embryonic stage 15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 360."
+ ],
+ "definition": {
+ "val": "Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005333",
+ "lbl": "late embryonic stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 370."
+ ],
+ "definition": {
+ "val": "Embryonic stages 16-17.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005334",
+ "lbl": "embryonic stage 16",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 380."
+ ],
+ "definition": {
+ "val": "Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005335",
+ "lbl": "embryonic stage 17",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 390."
+ ],
+ "definition": {
+ "val": "Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005336",
+ "lbl": "larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 400."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005337",
+ "lbl": "first instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 410."
+ ],
+ "definition": {
+ "val": "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L1",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "first instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000000"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005338",
+ "lbl": "second instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 420."
+ ],
+ "definition": {
+ "val": "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L2",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "second instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000001"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005339",
+ "lbl": "third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 430."
+ ],
+ "definition": {
+ "val": "The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L3",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "third instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000002"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005340",
+ "lbl": "early third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T11:51:56Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 440."
+ ],
+ "definition": {
+ "val": "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005341",
+ "lbl": "wandering third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T11:55:46Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 460."
+ ],
+ "definition": {
+ "val": "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "late third instar",
+ "xrefs": []
+ },
+ {
+ "pred": "hasBroadSynonym",
+ "val": "post-feeding larva",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005342",
+ "lbl": "prepupal stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 500."
+ ],
+ "definition": {
+ "val": "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005343",
+ "lbl": "prepupal stage P1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 510."
+ ],
+ "definition": {
+ "val": "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P1",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "puparium formation",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "white puparium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "pupal stage P0",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "white prepupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005344",
+ "lbl": "prepupal stage P2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 520."
+ ],
+ "definition": {
+ "val": "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "brown puparium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P2",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005345",
+ "lbl": "prepupal stage P3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 530."
+ ],
+ "definition": {
+ "val": "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "bubble prepupa stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P3",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005346",
+ "lbl": "prepupal stage P4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 540."
+ ],
+ "definition": {
+ "val": "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cryptocephalic pupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005347",
+ "lbl": "prepupal stage P4(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 550."
+ ],
+ "definition": {
+ "val": "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "buoyant stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005348",
+ "lbl": "prepupal stage P4(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 560."
+ ],
+ "definition": {
+ "val": "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "moving bubble stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4(ii)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005349",
+ "lbl": "pupal stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 570. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for Cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head and expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage."
+ ],
+ "definition": {
+ "val": "The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "phanerocephalic pupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005350",
+ "lbl": "pupal stage P5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 580."
+ ],
+ "definition": {
+ "val": "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005351",
+ "lbl": "pupal stage P5(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 590."
+ ],
+ "definition": {
+ "val": "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "Malpighian tubules migrating",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005352",
+ "lbl": "pupal stage P5(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 600."
+ ],
+ "definition": {
+ "val": "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "white Malpighian tubules stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005353",
+ "lbl": "pupal stage P6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 610."
+ ],
+ "definition": {
+ "val": "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "green Malpighian tubules stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005354",
+ "lbl": "pupal stage P7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 620."
+ ],
+ "definition": {
+ "val": "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "yellow body stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005355",
+ "lbl": "pharate adult stage P8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 630."
+ ],
+ "definition": {
+ "val": "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P8",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "yellow-eyed stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005356",
+ "lbl": "pharate adult stage P9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 640."
+ ],
+ "definition": {
+ "val": "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "amber-eyed stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P9",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005357",
+ "lbl": "pharate adult stage P10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 650."
+ ],
+ "definition": {
+ "val": "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P10",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "red-eye bald stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005358",
+ "lbl": "pharate adult stage P11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 660."
+ ],
+ "definition": {
+ "val": "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005359",
+ "lbl": "pharate adult stage P11(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 670."
+ ],
+ "definition": {
+ "val": "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "head bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005360",
+ "lbl": "pharate adult stage P11(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 680."
+ ],
+ "definition": {
+ "val": "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11(ii)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "thoracic bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005361",
+ "lbl": "pharate adult stage P12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 690."
+ ],
+ "definition": {
+ "val": "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005362",
+ "lbl": "pharate adult stage P12(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 700."
+ ],
+ "definition": {
+ "val": "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12(i)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wing tips grey stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005363",
+ "lbl": "pharate adult stage P12(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 710."
+ ],
+ "definition": {
+ "val": "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12(ii)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wings grey stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005364",
+ "lbl": "pharate adult stage P13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 720."
+ ],
+ "definition": {
+ "val": "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P13",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wings black stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005365",
+ "lbl": "pharate adult stage P14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 730."
+ ],
+ "definition": {
+ "val": "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "mature bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P14",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005366",
+ "lbl": "pharate adult stage P15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 740."
+ ],
+ "definition": {
+ "val": "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005367",
+ "lbl": "pharate adult stage P15(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 750."
+ ],
+ "definition": {
+ "val": "Tanning of the tergites obscures the Malpighian tubules and the 'yellow body'. Legs begin to twitch; fly is able to walk if puparium is removed prematurely. Ptilinum expands by hydrostatic pressure, opening the operculum. Duration at 25 degrees C: approximately 8 hours, 6 minutes. (211.5-219.6 hours after egg laying; 91.5-99.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "meconium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005368",
+ "lbl": "pharate adult stage P15(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 760."
+ ],
+ "definition": {
+ "val": "Stage which starts when the operculum opens and ends when eclosion is completed. Duration at 25 degrees C: approximately 24 minutes. (219.6-220 hours after egg laying; 99.6-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "eclosion stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15(ii)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005369",
+ "lbl": "adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 770."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from eclosion to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005370",
+ "lbl": "adult stage A1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005373"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 785. The time at which eclosed flies settle down for wing expansion can vary greatly. If they fail to find a suitable site then expansion can be delayed by several hours."
+ ],
+ "definition": {
+ "val": "Newly eclosed adult stage. Animal free of pupal case. Runs rapidly to find site for wing expansion. Wings are folded back and black against a very pale abdomen.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage I",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005371",
+ "lbl": "adult stage A2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005374"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 790."
+ ],
+ "definition": {
+ "val": "Stage, shortly after eclosion, during which the wings expand. During wing expansion, the abdomen pulsates and the hind legs stroke the wings vigorously for several minutes at a time. The stage ends when the wings are folded down over the abdomen, which has become broader and shorter, and the wing cuticle has lost its folds. The stage lasts around 15 minutes at 25'C.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage II",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005412",
+ "lbl": "gamete",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "This should be considered as a type of cell rather than as a stage. Please use FBbt:00005412."
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00006011",
+ "lbl": "pharate adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 625."
+ ],
+ "definition": {
+ "val": "The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355",
+ "FlyBase:FBrf0049147"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00006012",
+ "lbl": "adult stage A3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005375"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 800."
+ ],
+ "definition": {
+ "val": "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage III",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007000",
+ "lbl": "spermatogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-06-05T04:51:08Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 20000."
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0007283"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007001",
+ "lbl": "P-stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-06-05T04:51:40Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 490. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head an expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "metamorphosis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "pupal stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007002",
+ "lbl": "oogenesis stage S11a",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10140."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins and ends when the dorsal appendages begin to form.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007003",
+ "lbl": "oogenesis stage S11b",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10150."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when endochorion begins to form at the anterior pole, a process which includes the beginning of formation of the dorsal appendages. During this stage, the follicle cells secrete membranous vesicles that form irregular extracellular plaques. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007004",
+ "lbl": "third instar larval stage L1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 470."
+ ],
+ "definition": {
+ "val": "Stage which begins when wandering third instar larva stops crawling. The larva everts its anterior spiracles during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007005",
+ "lbl": "third instar larval stage L2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 480."
+ ],
+ "definition": {
+ "val": "The anterior spiracles are fully everted, with 7-9 finger-like projections. The body shortens, withdrawing three apparent abdominal segments and the larva sticks to its substrate.",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "spiracles everted larva",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "white prepupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007006",
+ "lbl": "oogenesis stage S13E",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T06:27:57Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10250."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007007",
+ "lbl": "late third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-12-11T01:19:53Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 450."
+ ],
+ "definition": {
+ "val": "Third instar larva from the beginning of wandering to the beginning of puparium formation.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007008",
+ "lbl": "occurrent",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007009",
+ "lbl": "developmental process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:56:42Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0032502"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007011",
+ "lbl": "embryonic cycle",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:57:41Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.",
+ "xrefs": [
+ "FlyBase:FBrf0049535",
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007012",
+ "lbl": "life stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:59:22Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "life cycle stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007013",
+ "lbl": "age",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-29T12:25:36Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007014",
+ "lbl": "adult age in days",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-29T12:28:05Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Temporal subdivision of adulthood in days post-eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007015",
+ "lbl": "embryonic stage 17(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T11:57:15Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007016",
+ "lbl": "embryonic stage 17(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:00:15Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 392. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007017",
+ "lbl": "embryonic stage 17(iii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:01:18Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 393. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007018",
+ "lbl": "embryonic stage 17(iv)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:03:14Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 394. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007019",
+ "lbl": "third instar - uncleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994)."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007020",
+ "lbl": "third instar - partially cleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994)."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007021",
+ "lbl": "third instar - cleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage when the larva has cleared its gut contents.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007022",
+ "lbl": "embryonic cycle interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The interphase (GO:0051325) of an embryonic cycle.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007023",
+ "lbl": "embryonic cycle M-phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The M-phase (GO:0000279) of an embryonic cycle.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007024",
+ "lbl": "biological process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0008150"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007025",
+ "lbl": "immature adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-01-08T20:06:59Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 782."
+ ],
+ "definition": {
+ "val": "The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007026",
+ "lbl": "mature adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-01-10T13:03:54Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Life stage from the end of adult stage A3, when tanning is complete, to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007075",
+ "lbl": "day 0 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 780."
+ ],
+ "definition": {
+ "val": "The day of eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007076",
+ "lbl": "day 1 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 810."
+ ],
+ "definition": {
+ "val": "1st day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007077",
+ "lbl": "day 2 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 820."
+ ],
+ "definition": {
+ "val": "2nd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007078",
+ "lbl": "day 3 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 830."
+ ],
+ "definition": {
+ "val": "3rd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007079",
+ "lbl": "day 4 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 840."
+ ],
+ "definition": {
+ "val": "4th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007080",
+ "lbl": "day 5 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 850."
+ ],
+ "definition": {
+ "val": "5th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007081",
+ "lbl": "day 6 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 860."
+ ],
+ "definition": {
+ "val": "6th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007082",
+ "lbl": "day 7 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 870."
+ ],
+ "definition": {
+ "val": "7th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007083",
+ "lbl": "day 8 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 880."
+ ],
+ "definition": {
+ "val": "8th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007084",
+ "lbl": "day 9 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 890."
+ ],
+ "definition": {
+ "val": "9th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007085",
+ "lbl": "day 10 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 900."
+ ],
+ "definition": {
+ "val": "10th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007086",
+ "lbl": "day 11 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 910."
+ ],
+ "definition": {
+ "val": "11th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007087",
+ "lbl": "day 12 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 920."
+ ],
+ "definition": {
+ "val": "12th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007088",
+ "lbl": "day 13 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 930."
+ ],
+ "definition": {
+ "val": "13th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007089",
+ "lbl": "day 14 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 940."
+ ],
+ "definition": {
+ "val": "14th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007090",
+ "lbl": "day 15 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 950."
+ ],
+ "definition": {
+ "val": "15th day after eclosion.",
+ "xrefs": [
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+ ],
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+ "Temporal ordering number - 990."
+ ],
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+ "Temporal ordering number - 1000."
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+ "Temporal ordering number - 1010."
+ ],
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+ ],
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+ "Temporal ordering number - 1030."
+ ],
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+ "Temporal ordering number - 1040."
+ ],
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+ "Temporal ordering number - 1050."
+ ],
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+ "Temporal ordering number - 1060."
+ ],
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+ "Temporal ordering number - 1070."
+ ],
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+ "Temporal ordering number - 1080."
+ ],
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+ "Temporal ordering number - 1140."
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+ "Temporal ordering number - 1170."
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+ "Temporal ordering number - 1190."
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+ "Temporal ordering number - 1200."
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+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007131",
+ "lbl": "day 56 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1360."
+ ],
+ "definition": {
+ "val": "56th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007132",
+ "lbl": "day 57 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1370."
+ ],
+ "definition": {
+ "val": "57th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007133",
+ "lbl": "day 58 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1380."
+ ],
+ "definition": {
+ "val": "58th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007134",
+ "lbl": "day 59 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1390."
+ ],
+ "definition": {
+ "val": "59th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007135",
+ "lbl": "day 60 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1400."
+ ],
+ "definition": {
+ "val": "60th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00014201",
+ "lbl": "early extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 270."
+ ],
+ "definition": {
+ "val": "A collective term for stages 9 and 10.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00018001",
+ "lbl": "substage_of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "substage_of"
+ }
+ ],
+ "comments": [
+ "Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO."
+ ],
+ "xrefs": [
+ {
+ "val": "FBdv:00018001"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000087",
+ "lbl": "mitotic M phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "M phase of mitotic cell cycle",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "M-phase of mitotic cell cycle",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000278",
+ "lbl": "mitotic cell cycle",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0007067"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle."
+ ],
+ "definition": {
+ "val": "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.",
+ "xrefs": [
+ "GOC:mah",
+ "ISBN:0815316194",
+ "Reactome:69278"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_drosophila",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_yeast"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "mitosis",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Mitosis"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000279",
+ "lbl": "M phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "M-phase",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:M_phase"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000280",
+ "lbl": "nuclear division",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "karyokinesis",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0003674",
+ "lbl": "molecular_function",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "molecular process"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0006996",
+ "lbl": "organelle organization",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-12-19T15:25:51Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:1902589"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_candida",
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "organelle organisation",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "single organism organelle organization",
+ "xrefs": [
+ "GOC:TermGenie"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "organelle organization and biogenesis",
+ "xrefs": [
+ "GOC:dph",
+ "GOC:jl",
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism organelle organization",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0007049",
+ "lbl": "cell cycle",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.",
+ "xrefs": [
+ "GOC:go_curators",
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate",
+ "http://purl.obolibrary.org/obo/go#goslim_agr",
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_candida",
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cell-division cycle",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Cell_cycle"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0007275",
+ "lbl": "multicellular organism development",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term was 'developmental process'."
+ ],
+ "definition": {
+ "val": "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",
+ "xrefs": [
+ "GOC:dph",
+ "GOC:ems",
+ "GOC:isa_complete",
+ "GOC:tb"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0008150",
+ "lbl": "biological_process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-09-19T15:05:24Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0000004"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0007582"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044699"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this."
+ ],
+ "definition": {
+ "val": "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.",
+ "xrefs": [
+ "GOC:pdt"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_candida",
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_metagenomics",
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_plant",
+ "http://purl.obolibrary.org/obo/go#goslim_pombe",
+ "http://purl.obolibrary.org/obo/go#goslim_yeast"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "biological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "physiological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single organism process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism process",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Biological_process"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0009790",
+ "lbl": "embryo development",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0009795"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.",
+ "xrefs": [
+ "GOC:go_curators",
+ "GOC:isa_complete",
+ "GOC:mtg_sensu"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate",
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "embryogenesis and morphogenesis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryogenesis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonal development",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Embryogenesis"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0009987",
+ "lbl": "cellular process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-12-11T16:56:55Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0008151"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044763"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0050875"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",
+ "xrefs": [
+ "GOC:go_curators",
+ "GOC:isa_complete"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cell physiology",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular physiological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "cell growth and/or maintenance",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism cellular process",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0016043",
+ "lbl": "cellular component organization",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044235"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0071842"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.",
+ "xrefs": [
+ "GOC:ai",
+ "GOC:jl",
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_agr",
+ "http://purl.obolibrary.org/obo/go#goslim_mouse",
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cell organisation",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation at cellular level",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation in other organism",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organization at cellular level",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organization in other organism",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "cell organization and biogenesis",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0022402",
+ "lbl": "cell cycle process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.",
+ "xrefs": [
+ "GOC:isa_complete",
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0022403",
+ "lbl": "cell cycle phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0032501",
+ "lbl": "multicellular organismal process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002161",
+ "val": "http://purl.obolibrary.org/obo/NCBITaxon_4896"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002161",
+ "val": "http://purl.obolibrary.org/obo/NCBITaxon_4932"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-09-19T16:07:47Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044707"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0050874"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "Any biological process, occurring at the level of a multicellular organism, pertinent to its function.",
+ "xrefs": [
+ "GOC:curators",
+ "GOC:dph",
+ "GOC:isa_complete",
+ "GOC:tb"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "organismal physiological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-multicellular organism process",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0032502",
+ "lbl": "developmental process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-12-19T12:21:31Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044767"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.",
+ "xrefs": [
+ "GOC:isa_complete"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_agr",
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon",
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "development",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism developmental process",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0044848",
+ "lbl": "biological phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2014-07-16T13:12:40Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase."
+ ],
+ "definition": {
+ "val": "A distinct period or stage in a biological process or cycle.",
+ "xrefs": [
+ "GOC:jl"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0045448",
+ "lbl": "mitotic cell cycle, embryonic",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.",
+ "xrefs": [
+ "GOC:go_curators"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0048285",
+ "lbl": "organelle fission",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The creation of two or more organelles by division of one organelle.",
+ "xrefs": [
+ "GOC:jid"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_yeast"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0048856",
+ "lbl": "anatomical structure development",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.",
+ "xrefs": [
+ "GO_REF:0000021"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "development of an anatomical structure",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0051325",
+ "lbl": "interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "resting phase",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "karyostasis",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Interphase"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0051329",
+ "lbl": "mitotic interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "interphase of mitotic cell cycle",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0071840",
+ "lbl": "cellular component organization or biogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "mah"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-10T01:39:16Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0071841"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon",
+ "http://purl.obolibrary.org/obo/go#goslim_metagenomics"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation or biogenesis",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation or biogenesis at cellular level",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organization or biogenesis at cellular level",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0098763",
+ "lbl": "mitotic cell cycle phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0140014",
+ "lbl": "mitotic nuclear division",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000233",
+ "val": "https://github.com/geneontology/go-ontology/issues/19910"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "pg"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-03-23T14:44:23Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",
+ "xrefs": [
+ "ISBN:0198547684"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "mitosis",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_1903047",
+ "lbl": "mitotic cell cycle process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2014-05-22T14:22:34Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that is part of the mitotic cell cycle.",
+ "xrefs": [
+ "GOC:TermGenie",
+ "GOC:mtg_cell_cycle",
+ "GO_REF:0000060"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/IAO_0000115",
+ "lbl": "definition",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000122"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/PATO_0000001",
+ "lbl": "quality",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "quality (PATO)"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0000056",
+ "lbl": "participates in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "participates in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this blood clot participates in this blood coagulation"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this input material (or this output material) participates in this process"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this investigator participates in this investigation"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "participates_in"
+ }
+ ],
+ "definition": {
+ "val": "a relation between a continuant and a process, in which the continuant is somehow involved in the process",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0000057",
+ "lbl": "has participant",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "has participant"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this blood coagulation has participant this blood clot"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this investigation has participant this investigator"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this process has participant this input material (or this output material)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has_participant"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/source",
+ "val": "http://www.obofoundry.org/ro/#OBO_REL:has_participant"
+ }
+ ],
+ "definition": {
+ "val": "a relation between a process and a continuant, in which the continuant is somehow involved in the process",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002012",
+ "lbl": "occurent part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "occurent_part_of"
+ }
+ ],
+ "definition": {
+ "val": "A part of relation that applies only between occurents.",
+ "xrefs": []
+ },
+ "xrefs": [
+ {
+ "val": "RO:0002012"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002013",
+ "lbl": "has regulatory component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:30:46Z"
+ }
+ ],
+ "definition": {
+ "val": "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002014",
+ "lbl": "has negative regulatory component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:31:01Z"
+ }
+ ],
+ "comments": [
+ "By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'."
+ ],
+ "definition": {
+ "val": "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002015",
+ "lbl": "has positive regulatory component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:31:17Z"
+ }
+ ],
+ "comments": [
+ "By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'."
+ ],
+ "definition": {
+ "val": "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002017",
+ "lbl": "has component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:44:33Z"
+ }
+ ],
+ "comments": [
+ "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B."
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002018",
+ "lbl": "has component process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:49:21Z"
+ }
+ ],
+ "definition": {
+ "val": "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002022",
+ "lbl": "directly regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-17T13:52:24Z"
+ }
+ ],
+ "comments": [
+ "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2."
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002023",
+ "lbl": "directly negatively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-17T13:52:38Z"
+ }
+ ],
+ "definition": {
+ "val": "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002024",
+ "lbl": "directly positively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-17T13:52:47Z"
+ }
+ ],
+ "definition": {
+ "val": "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002025",
+ "lbl": "has effector activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-22T14:14:36Z"
+ }
+ ],
+ "comments": [
+ "This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations."
+ ],
+ "definition": {
+ "val": "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002084",
+ "lbl": "during which ends",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ }
+ ],
+ "comments": [
+ "Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range."
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002085",
+ "lbl": "encompasses",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "di"
+ }
+ ],
+ "comments": [
+ "Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range."
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002086",
+ "lbl": "ends after",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ }
+ ],
+ "comments": [
+ "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002087",
+ "lbl": "immediately_preceded_by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "starts_at_end_of"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "immediately_preceded_by"
+ }
+ ],
+ "comments": [
+ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002087"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002088",
+ "lbl": "during which starts",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ }
+ ],
+ "comments": [
+ "Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range."
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002090",
+ "lbl": "ends_at_start_of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "ends_at_start_of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "meets"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002575",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000063"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "ends_at_start_of"
+ }
+ ],
+ "comments": [
+ "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002090"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002091",
+ "lbl": "starts during",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "io"
+ }
+ ],
+ "comments": [
+ "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002092",
+ "lbl": "happens during",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "d"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "during"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "happens_during"
+ }
+ ],
+ "comments": [
+ "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002092"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002093",
+ "lbl": "ends during",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "o"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "overlaps"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "ends_during"
+ }
+ ],
+ "comments": [
+ "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). "
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002093"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002131",
+ "lbl": "overlaps",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000424",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "overlaps"
+ }
+ ],
+ "definition": {
+ "val": "x overlaps y if and only if there exists some z such that x has part z and z part of y",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002131"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002180",
+ "lbl": "has component",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Submissions:Componency"
+ }
+ ],
+ "definition": {
+ "val": "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002202",
+ "lbl": "develops from",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Melissa Haendel"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Terry Meehan"
+ }
+ ],
+ "comments": [
+ "This is the transitive form of the develops from relation"
+ ],
+ "definition": {
+ "val": "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002203",
+ "lbl": "develops into",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Terry Meehan"
+ }
+ ],
+ "definition": {
+ "val": "inverse of develops from",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002211",
+ "lbl": "regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Hill"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Tanya Berardini"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "GO"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Regulation precludes parthood; the regulatory process may not be within the regulated process."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "regulates (processual)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000600",
+ "val": "false"
+ }
+ ],
+ "definition": {
+ "val": "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002212",
+ "lbl": "negatively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "negatively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002211"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002213",
+ "lbl": "positively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "positively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002211"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002215",
+ "lbl": "capable of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "osteoclast SubClassOf 'capable of' some 'bone resorption'"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has function realized in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/20123131"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/21208450"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"."
+ }
+ ],
+ "definition": {
+ "val": "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. ",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002216",
+ "lbl": "capable of part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has function in"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "https://github.com/oborel/obo-relations/wiki/ROGuide#defining-property-chains-involving-reflexivity"
+ }
+ ],
+ "definition": {
+ "val": "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002222",
+ "lbl": "temporally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "https://en.wikipedia.org/wiki/Allen%27s_interval_algebra"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends."
+ },
+ {
+ "pred": "http://purl.org/dc/terms/source",
+ "val": "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1"
+ }
+ ],
+ "comments": [
+ "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations."
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002233",
+ "lbl": "has input",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "consumes"
+ }
+ ],
+ "definition": {
+ "val": "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002254",
+ "lbl": "has developmental contribution from",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has developmental contribution from y iff x has some part z such that z develops from y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002255",
+ "lbl": "developmentally contributes to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of has developmental contribution from",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002258",
+ "lbl": "developmentally preceded by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "false"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "In general you should not use this relation to make assertions - use one of the more specific relations below this one"
+ }
+ ],
+ "comments": [
+ "This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from"
+ ],
+ "definition": {
+ "val": "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002263",
+ "lbl": "acts upstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision."
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of"
+ }
+ ],
+ "definition": {
+ "val": "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002264",
+ "lbl": "acts upstream of or within",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway."
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within"
+ }
+ ],
+ "definition": {
+ "val": "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "affects",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002286",
+ "lbl": "developmentally succeeded by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "Inverse of developmentally preceded by",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002304",
+ "lbl": "causally upstream of, positive effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002411"
+ },
+ {
+ "pred": "http://purl.org/dc/terms/creator",
+ "val": "cjm"
+ }
+ ],
+ "comments": [
+ "holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002305",
+ "lbl": "causally upstream of, negative effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002411"
+ },
+ {
+ "pred": "http://purl.org/dc/terms/creator",
+ "val": "cjm"
+ }
+ ],
+ "comments": [
+ "holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002314",
+ "lbl": "inheres in part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Because part_of is transitive, inheres in is a sub-relation of inheres in part of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "https://github.com/oborel/obo-relations/wiki/ROGuide#defining-property-chains-involving-reflexivity"
+ }
+ ],
+ "definition": {
+ "val": "q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002323",
+ "lbl": "mereotopologically related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ }
+ ],
+ "definition": {
+ "val": "A mereological relationship or a topological relationship",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002324",
+ "lbl": "developmentally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development"
+ }
+ ],
+ "definition": {
+ "val": "A relationship that holds between entities participating in some developmental process (GO:0032502)",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002327",
+ "lbl": "enables",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "a particular instances of akt-2 enables some instance of protein kinase activity"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "catalyzes"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "executes"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "is catalyzing"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "is executing"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time."
+ }
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002328",
+ "lbl": "functionally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This is a grouping relation that collects relations used for the purpose of connecting structure and function"
+ }
+ ],
+ "definition": {
+ "val": "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002329",
+ "lbl": "part of structure that is capable of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "false"
+ }
+ ],
+ "definition": {
+ "val": "this relation holds between c and p when c is part of some c', and c' is capable of p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002331",
+ "lbl": "involved in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "actively involved in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "enables part of"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Involved_in"
+ }
+ ],
+ "definition": {
+ "val": "c involved_in p if and only if c enables some process p', and p' is part of p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002333",
+ "lbl": "enabled by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of enables",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002334",
+ "lbl": "regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "regulated by (processual)"
+ }
+ ],
+ "definition": {
+ "val": "inverse of regulates",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002335",
+ "lbl": "negatively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of negatively regulates",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002336",
+ "lbl": "positively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of positively regulates",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002352",
+ "lbl": "input of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of has input",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259",
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002384",
+ "lbl": "has developmental potential involving",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002385",
+ "lbl": "has potential to developmentally contribute to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002387",
+ "lbl": "has potential to develop into",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has the potential to develop into y iff x develops into y or if x is capable of developing into y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002388",
+ "lbl": "has potential to directly develop into",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002404",
+ "lbl": "causally downstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of upstream of",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002405",
+ "lbl": "immediately causally downstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002410",
+ "lbl": "causally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ }
+ ],
+ "definition": {
+ "val": "This relation groups causal relations between material entities and causal relations between processes",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002411",
+ "lbl": "causally upstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002412",
+ "lbl": "immediately causally upstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002575",
+ "val": "http://purl.obolibrary.org/obo/RO_0002411"
+ }
+ ],
+ "definition": {
+ "val": "p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002418",
+ "lbl": "causally upstream of or within",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "influences (processual)"
+ }
+ ],
+ "definition": {
+ "val": "p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "affects",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002427",
+ "lbl": "causally downstream of or within",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "inverse of causally upstream of or within",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002428",
+ "lbl": "involved in regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "c involved in regulation of p if c is involved in some p' and p' regulates some p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002429",
+ "lbl": "involved in positive regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002428"
+ }
+ ],
+ "definition": {
+ "val": "c involved in regulation of p if c is involved in some p' and p' positively regulates some p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002430",
+ "lbl": "involved in negative regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002428"
+ }
+ ],
+ "definition": {
+ "val": "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002431",
+ "lbl": "involved in or involved in regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "OWL does not allow defining object properties via a Union"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "involved in or reguates"
+ }
+ ],
+ "definition": {
+ "val": "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002432",
+ "lbl": "is active in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "A protein that enables activity in a cytosol."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "executes activity in"
+ }
+ ],
+ "comments": [
+ ""
+ ],
+ "definition": {
+ "val": "c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.",
+ "xrefs": [
+ "GOC:cjm",
+ "GOC:dos"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "enables activity in",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002434",
+ "lbl": "interacts with",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Considering relabeling as 'pairwise interacts with'"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules."
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/MI_0914"
+ },
+ {
+ "pred": "http://xmlns.com/foaf/0.1/page",
+ "val": "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
+ }
+ ],
+ "definition": {
+ "val": "A relationship that holds between two entities in which the processes executed by the two entities are causally connected.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "in pairwise interaction with",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002436",
+ "lbl": "molecularly interacts with",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "binds"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "molecularly binds with"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/ECO_0000353"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/MI_0915"
+ }
+ ],
+ "definition": {
+ "val": "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002447",
+ "lbl": "phosphorylates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Axiomatization to GO to be added later"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y."
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002448",
+ "lbl": "directly regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ }
+ ],
+ "definition": {
+ "val": "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "molecularly controls",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002449",
+ "lbl": "directly negatively regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "directly inhibits"
+ }
+ ],
+ "definition": {
+ "val": "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "molecularly decreases activity of",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002450",
+ "lbl": "directly positively regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "directly activates"
+ }
+ ],
+ "definition": {
+ "val": "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "molecularly increases activity of",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002464",
+ "lbl": "helper property (not for use in curation)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning."
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002479",
+ "lbl": "has part that occurs in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002481",
+ "lbl": "is kinase activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002500",
+ "lbl": "causal agent in process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "A relationship between a material entity and a process where the material entity has some causal role that influences the process",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002501",
+ "lbl": "causal relation between processes",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ }
+ ],
+ "definition": {
+ "val": "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002502",
+ "lbl": "depends on",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000169"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002506",
+ "lbl": "causal relation between entities",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002559",
+ "lbl": "causally influenced by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "causally influenced by (entity-centric)"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002563",
+ "lbl": "interaction relation helper property",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29"
+ },
+ {
+ "pred": "http://xmlns.com/foaf/0.1/page",
+ "val": "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002564",
+ "lbl": "molecular interaction relation helper property",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002566",
+ "lbl": "causally influences",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "causally influences (entity-centric)"
+ }
+ ],
+ "definition": {
+ "val": "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002573",
+ "lbl": "has modifier",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the \"modifiers\" are."
+ }
+ ],
+ "definition": {
+ "val": "A relation that holds between an attribute or a qualifier and another attribute.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002578",
+ "lbl": "directly regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "directly regulates (processual)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002575",
+ "val": "http://purl.obolibrary.org/obo/RO_0002211"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002581",
+ "lbl": "is a defining property chain axiom",
+ "meta": {
+ "definition": {
+ "val": "If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002582",
+ "lbl": "is a defining property chain axiom where second argument is reflexive",
+ "meta": {
+ "definition": {
+ "val": "If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002584",
+ "lbl": "has part structure that is capable of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002595",
+ "lbl": "causal relation between material entity and a process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002596",
+ "lbl": "capable of regulating",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "pyrethroid -> growth"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Holds between c and p if and only if c is capable of some activity a, and a regulates p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002597",
+ "lbl": "capable of negatively regulating",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002598",
+ "lbl": "capable of positively regulating",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "renin -> arteriolar smooth muscle contraction"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002608",
+ "lbl": "process has causal agent",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Inverse of 'causal agent in process'",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002629",
+ "lbl": "directly positively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "directly positively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002578"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002630",
+ "lbl": "directly negatively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "directly negatively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002578"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004031",
+ "lbl": "enables subfunction",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-25T23:20:13Z"
+ }
+ ],
+ "definition": {
+ "val": "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004032",
+ "lbl": "acts upstream of or within, positive effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002264"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-26T23:49:30Z"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect"
+ }
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004033",
+ "lbl": "acts upstream of or within, negative effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002264"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-26T23:49:51Z"
+ }
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004034",
+ "lbl": "acts upstream of, positive effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002263"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-26T23:53:14Z"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of,_positive_effect"
+ }
+ ],
+ "definition": {
+ "val": "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004035",
+ "lbl": "acts upstream of, negative effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002263"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-26T23:53:22Z"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of,_negative_effect"
+ }
+ ],
+ "definition": {
+ "val": "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004046",
+ "lbl": "causally upstream of or within, negative effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002418"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-03-13T23:55:05Z"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004047",
+ "lbl": "causally upstream of or within, positive effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002418"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-03-13T23:55:19Z"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0011002",
+ "lbl": "regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ }
+ ],
+ "definition": {
+ "val": "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/fbdv#systematic_synonym",
+ "lbl": "Systematic synonym",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasScope",
+ "val": "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/CARO_0030000",
+ "lbl": "biological entity",
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0003824",
+ "lbl": "catalytic activity",
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0016301",
+ "lbl": "kinase activity",
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0016740",
+ "lbl": "transferase activity",
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0016772",
+ "lbl": "transferase activity, transferring phosphorus-containing groups",
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "lbl": "term replaced by",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule",
+ "lbl": "namespace-id-rule",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#SubsetProperty",
+ "lbl": "subset_property",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty",
+ "lbl": "synonym_type_property",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "lbl": "has_alternative_id",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym",
+ "lbl": "has_broad_synonym",
+ "type": "PROPERTY"
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- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002093", "http://purl.obolibrary.org/obo/BFO_0000062" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002597",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/RO_0002212" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002091", "http://purl.obolibrary.org/obo/BFO_0000062" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002216",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002566",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002411", "http://purl.obolibrary.org/obo/RO_0002333" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002428",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002331", "http://purl.obolibrary.org/obo/RO_0002211" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000066",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000050", "http://purl.obolibrary.org/obo/BFO_0000066" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002598",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/RO_0002213" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0004031",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/BFO_0000051" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002131",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000051", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002211",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002211", "http://purl.obolibrary.org/obo/RO_0002025" ]
- } ]
- } ]
-}
\ No newline at end of file
+ ]
+ }
+ ]
+}
diff --git a/fbdv-non-classified.obo b/fbdv-non-classified.obo
index 8048e6f..4a26289 100644
--- a/fbdv-non-classified.obo
+++ b/fbdv-non-classified.obo
@@ -1,6 +1,6 @@
format-version: 1.2
-data-version: fbdv/releases/2021-01-13/fbdv-non-classified.owl
-date: 13:01:2021 12:25
+data-version: fbdv/releases/2021-03-10/fbdv-non-classified.owl
+date: 10:03:2021 10:38
subsetdef: gocheck_do_not_annotate ""
subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation"
subsetdef: gocheck_do_not_manually_annotate ""
@@ -50,7 +50,7 @@ property_value: IAO:0000700 FBdv:00000000
property_value: IAO:0000700 FBdv:00005259
property_value: IAO:0000700 FBdv:00007013
property_value: IAO:0000700 FBdv:00007024
-property_value: owl:versionInfo "2021-01-13" xsd:string
+property_value: owl:versionInfo "2021-03-10" xsd:string
[Term]
id: BFO:0000002
@@ -397,6 +397,7 @@ comment: Temporal ordering number - 10.
is_a: FBdv:00005259 ! developmental stage
relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
relationship: substage_of FBdv:00005286 ! egg stage
+relationship: substage_of FBdv:00005289 ! embryonic stage
[Term]
id: FBdv:00005289
@@ -404,7 +405,7 @@ name: embryonic stage
def: "The stage of the Drosophila life-cycle from fertilization to hatching." [FBC:DOS]
comment: Temporal ordering number - 20.
is_a: FBdv:00007012 ! life stage
-relationship: immediately_preceded_by FBdv:00005288 ! fertilized egg stage
+relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
[Term]
id: FBdv:00005290
@@ -850,6 +851,7 @@ def: "The first larval instar begins at hatching and ends at the first larval mo
comment: Temporal ordering number - 410.
synonym: "first instar larva" EXACT []
synonym: "L1" EXACT []
+xref: UBERON:8000000
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005289 ! embryonic stage
relationship: immediately_preceded_by FBdv:00005333 ! late embryonic stage
@@ -864,6 +866,7 @@ def: "The second larval instar begins at the first larval molt and ends at the s
comment: Temporal ordering number - 420.
synonym: "L2" EXACT []
synonym: "second instar larva" EXACT []
+xref: UBERON:8000001
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005337 ! first instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -875,6 +878,7 @@ def: "The third larval instar begins at the second larval molt and ends at pupar
comment: Temporal ordering number - 430.
synonym: "L3" EXACT []
synonym: "third instar larva" RELATED []
+xref: UBERON:8000002
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005338 ! second instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -2707,7 +2711,6 @@ id: RO:0002211
name: regulates
def: "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
-subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
property_value: IAO:0000114 IAO:0000125
@@ -2733,7 +2736,6 @@ id: RO:0002212
name: negatively regulates
def: "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
-subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
property_value: IAO:0000117 "Chris Mungall" xsd:string
@@ -2749,7 +2751,6 @@ id: RO:0002213
name: positively regulates
def: "Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2." []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
-subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
property_value: IAO:0000117 "Chris Mungall" xsd:string
diff --git a/fbdv-non-classified.owl b/fbdv-non-classified.owl
index bcd9484..a678902 100644
--- a/fbdv-non-classified.owl
+++ b/fbdv-non-classified.owl
@@ -18,7 +18,7 @@
xmlns:subsets="http://purl.obolibrary.org/obo/ro/subsets#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
-
+
@@ -31,10 +31,10 @@
FlyBase Developmental Ontology (FBdv)
https://creativecommons.org/licenses/by/3.0/
* FBdv:$sequence(8,7000,10000)$
- 13:01:2021 12:25
+ 10:03:2021 10:38
FlyBase_development_CV
1.2
- 2021-01-13
+ 2021-03-10
@@ -506,42 +506,18 @@
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
@@ -1404,7 +1380,6 @@ A continuant cannot have an occurrent as part: use 'participates in'.
regulates (processual)
false
-
regulates
@@ -1424,7 +1399,6 @@ A continuant cannot have an occurrent as part: use 'participates in'.
negatively regulates (process to process)
-
negatively regulates
@@ -1449,7 +1423,6 @@ A continuant cannot have an occurrent as part: use 'participates in'.
positively regulates (process to process)
-
positively regulates
@@ -3830,6 +3803,12 @@ For example, A and B may be gene products and binding of B by A positively regul
+
+
+
+
+
+
@@ -3851,7 +3830,7 @@ For example, A and B may be gene products and binding of B by A positively regul
-
+
The stage of the Drosophila life-cycle from fertilization to hatching.
@@ -5412,6 +5391,7 @@ For example, A and B may be gene products and binding of B by A positively regul
The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).
+ UBERON:8000000
L1
first instar larva
FlyBase_development_CV
@@ -5445,6 +5425,7 @@ For example, A and B may be gene products and binding of B by A positively regul
The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).
+ UBERON:8000001
L2
second instar larva
FlyBase_development_CV
@@ -5478,6 +5459,7 @@ For example, A and B may be gene products and binding of B by A positively regul
The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).
+ UBERON:8000002
L3
FlyBase_development_CV
third instar larva
@@ -9910,7 +9892,7 @@ For example, A and B may be gene products and binding of B by A positively regul
A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
- GOC:pdt
+ GOC:pdt
diff --git a/fbdv-simple.json b/fbdv-simple.json
index 07c1937..0b03380 100644
--- a/fbdv-simple.json
+++ b/fbdv-simple.json
@@ -1,6502 +1,9019 @@
{
- "graphs" : [ {
- "nodes" : [ {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005321",
- "meta" : {
- "definition" : {
- "val" : "Stages during which the germ band is extended - 9-12.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 260." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "extended germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005322",
- "meta" : {
- "definition" : {
- "val" : "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 250." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "rapidly extending germ band stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005320",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005314",
- "meta" : {
- "definition" : {
- "val" : "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "FlyBase:FBrf0039741" ]
- },
- "comments" : [ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "embryonic cycle 14 M-phase",
- "xrefs" : [ "FBC:DOS" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005315",
- "meta" : {
- "definition" : {
- "val" : "The 15th cell cycle of embryogenesis. Asynchronous.",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "second blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005312",
- "meta" : {
- "definition" : {
- "val" : "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "FlyBase:FBrf0049535", "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "first blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005313",
- "meta" : {
- "definition" : {
- "val" : "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "[FlyBase:FBrf0039741" ]
- },
- "comments" : [ "Temporal ordering number - 256." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "embryonic cycle 14 interphase",
- "xrefs" : [ "FBC:DOS" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005318",
- "meta" : {
- "definition" : {
- "val" : "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 230." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 6"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005319",
- "meta" : {
- "definition" : {
- "val" : "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 240." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005316",
- "meta" : {
- "definition" : {
- "val" : "The 16th cell cycle division of embryogenesis. Asynchronous.",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "third blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 16"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005317",
- "meta" : {
- "definition" : {
- "val" : "Stages during which gastrulation occurs. 6-8.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 220." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "gastrula",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "gastrula stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005310",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "cellular blastoderm stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005311",
- "meta" : {
- "definition" : {
- "val" : "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 210." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "cellular blastoderm stage",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "cellular blastoderm",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005303",
- "meta" : {
- "definition" : {
- "val" : "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 180." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005304",
- "meta" : {
- "definition" : {
- "val" : "Embryonic stages 4 and 5.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 160." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "blastoderm",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "blastoderm stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005301",
- "meta" : {
- "definition" : {
- "val" : "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 140." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005302",
- "meta" : {
- "definition" : {
- "val" : "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 150." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005307",
- "meta" : {
- "definition" : {
- "val" : "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 185." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005308",
- "meta" : {
- "definition" : {
- "val" : "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 190." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005305",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "syncytial blastoderm stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005306",
- "meta" : {
- "definition" : {
- "val" : "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 170." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "syncytial blastoderm stage",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "syncytial blastoderm",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 4"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym",
- "type" : "PROPERTY",
- "lbl" : "has_related_synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005309",
- "meta" : {
- "definition" : {
- "val" : "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 200." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007081",
- "meta" : {
- "definition" : {
- "val" : "6th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 860." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 6 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007080",
- "meta" : {
- "definition" : {
- "val" : "5th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 850." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 5 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007085",
- "meta" : {
- "definition" : {
- "val" : "10th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 900." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 10 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007084",
- "meta" : {
- "definition" : {
- "val" : "9th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 890." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 9 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007083",
- "meta" : {
- "definition" : {
- "val" : "8th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 880." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 8 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007082",
- "meta" : {
- "definition" : {
- "val" : "7th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 870." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 7 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007089",
- "meta" : {
- "definition" : {
- "val" : "14th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 940." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 14 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005340",
- "meta" : {
- "definition" : {
- "val" : "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 440." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-11-13T11:51:56Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "early third instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007088",
- "meta" : {
- "definition" : {
- "val" : "13th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 930." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 13 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007087",
- "meta" : {
- "definition" : {
- "val" : "12th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 920." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 12 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007086",
- "meta" : {
- "definition" : {
- "val" : "11th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 910." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 11 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005343",
- "meta" : {
- "definition" : {
- "val" : "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 510." ],
- "synonyms" : [ {
- "pred" : "hasNarrowSynonym",
- "val" : "pupal stage P0",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasNarrowSynonym",
- "val" : "white prepupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P1",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "puparium formation",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "white puparium stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P1"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005344",
- "meta" : {
- "definition" : {
- "val" : "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 520." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P2",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "brown puparium stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P2"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005341",
- "meta" : {
- "definition" : {
- "val" : "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 460." ],
- "synonyms" : [ {
- "pred" : "hasBroadSynonym",
- "val" : "post-feeding larva",
- "xrefs" : [ ]
- }, {
- "pred" : "hasBroadSynonym",
- "val" : "late third instar",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-11-13T11:55:46Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "wandering third instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005342",
- "meta" : {
- "definition" : {
- "val" : "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 500." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005336",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 400." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005337",
- "meta" : {
- "definition" : {
- "val" : "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).",
- "xrefs" : [ "FlyBase:FBrf0007733" ]
- },
- "comments" : [ "Temporal ordering number - 410." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "L1",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "first instar larva",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "first instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005334",
- "meta" : {
- "definition" : {
- "val" : "Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 380." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 16"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005335",
- "meta" : {
- "definition" : {
- "val" : "Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 390." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 17"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005338",
- "meta" : {
- "definition" : {
- "val" : "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).",
- "xrefs" : [ "FlyBase:FBrf0007733" ]
- },
- "comments" : [ "Temporal ordering number - 420." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "L2",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "second instar larva",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "second instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005339",
- "meta" : {
- "definition" : {
- "val" : "The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).",
- "xrefs" : [ "FlyBase:FBrf0007733" ]
- },
- "comments" : [ "Temporal ordering number - 430." ],
- "synonyms" : [ {
- "pred" : "hasRelatedSynonym",
- "val" : "third instar larva",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "L3",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "third instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/IAO_0100001",
- "type" : "PROPERTY",
- "lbl" : "term replaced by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007078",
- "meta" : {
- "definition" : {
- "val" : "3rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 830." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 3 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007077",
- "meta" : {
- "definition" : {
- "val" : "2nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 820." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 2 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007076",
- "meta" : {
- "definition" : {
- "val" : "1st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 810." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 1 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007075",
- "meta" : {
- "definition" : {
- "val" : "The day of eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 780." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 0 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005332",
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- "val" : "Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).",
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- },
- "comments" : [ "Temporal ordering number - 360." ],
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- "lbl" : "embryonic stage 15"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005333",
- "meta" : {
- "definition" : {
- "val" : "Embryonic stages 16-17.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 370." ],
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- "lbl" : "late embryonic stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005330",
- "meta" : {
- "definition" : {
- "val" : "Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).",
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- },
- "comments" : [ "Temporal ordering number - 350." ],
- "synonyms" : [ {
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- "lbl" : "embryonic stage 14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007079",
- "meta" : {
- "definition" : {
- "val" : "4th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 840." ],
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- "lbl" : "day 4 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005331",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 13-15.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 330." ],
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- "val" : "FlyBase_development_CV"
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- "lbl" : "dorsal closure stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005325",
- "meta" : {
- "definition" : {
- "val" : "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).",
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- },
- "comments" : [ "Temporal ordering number - 310." ],
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- "lbl" : "embryonic stage 11"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005326",
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- "type" : "CLASS",
- "lbl" : "contracted germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005323",
- "meta" : {
- "definition" : {
- "val" : "Stage 9 begins when mesodermal segmentation becomes (transiently) visible\\, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 280." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "embryonic stage 9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005324",
- "meta" : {
- "definition" : {
- "val" : "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 290." ],
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- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "embryonic stage 10"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005329",
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- "val" : "FBdv:00005330"
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- "val" : "FlyBase_development_CV"
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- "lbl" : "head involution stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005327",
- "meta" : {
- "definition" : {
- "val" : "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 320." ],
- "synonyms" : [ {
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- "lbl" : "embryonic stage 12"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005328",
- "meta" : {
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- "val" : "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 340." ],
- "synonyms" : [ {
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- "meta" : {
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- "val" : "The M-phase (GO:0000279) of an embryonic cycle.",
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- "lbl" : "embryonic cycle M-phase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002012",
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- "definition" : {
- "val" : "A part of relation that applies only between occurents.",
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- "xrefs" : [ {
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- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007022",
- "meta" : {
- "definition" : {
- "val" : "The interphase (GO:0051325) of an embryonic cycle.",
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007021",
- "meta" : {
- "definition" : {
- "val" : "The substage of the wandering third instar larval stage when the larva has cleared its gut contents.",
- "xrefs" : [ "FlyBase:FBrf0076598" ]
- },
- "comments" : [ "Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994." ],
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- "lbl" : "third instar - cleared gut stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007020",
- "meta" : {
- "definition" : {
- "val" : "The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.",
- "xrefs" : [ "FlyBase:FBrf0076598" ]
- },
- "comments" : [ "Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994)." ],
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- "lbl" : "third instar - partially cleared gut stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007026",
- "meta" : {
- "definition" : {
- "val" : "Life stage from the end of adult stage A3, when tanning is complete, to death.",
- "xrefs" : [ "FBC:DOS" ]
- },
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- "val" : "2013-01-10T13:03:54Z"
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- "lbl" : "mature adult stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007025",
- "meta" : {
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- "val" : "The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 782." ],
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- },
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- "lbl" : "immature adult stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002131",
- "meta" : {
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- "val" : "x overlaps y if and only if there exists some z such that x has part z and z part of y",
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- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
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- "lbl" : "overlaps"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007024",
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- "lbl" : "biological process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007019",
- "meta" : {
- "definition" : {
- "val" : "The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.",
- "xrefs" : [ "FlyBase:FBrf0076598" ]
- },
- "comments" : [ "Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994)." ],
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- "lbl" : "third instar - uncleared gut stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007018",
- "meta" : {
- "definition" : {
- "val" : "Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 394. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007017",
- "meta" : {
- "definition" : {
- "val" : "Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 393. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
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- "lbl" : "embryonic stage 17(iii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007012",
- "meta" : {
- "definition" : {
- "val" : "A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "synonyms" : [ {
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- } ],
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- },
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- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007133",
- "meta" : {
- "definition" : {
- "val" : "58th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1380." ],
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- "lbl" : "day 58 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007132",
- "meta" : {
- "definition" : {
- "val" : "57th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1370." ],
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- "lbl" : "day 57 of adulthood"
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- "val" : "A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.",
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- }, {
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- "val" : "56th day after eclosion.",
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- },
- "comments" : [ "Temporal ordering number - 1360." ],
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- "val" : "55th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1350." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 55 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007016",
- "meta" : {
- "definition" : {
- "val" : "Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 392. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "djs93"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2011-04-26T12:00:15Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 17(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007015",
- "meta" : {
- "definition" : {
- "val" : "The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2011-04-26T11:57:15Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "djs93"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 17(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007135",
- "meta" : {
- "definition" : {
- "val" : "60th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1400." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 60 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007014",
- "meta" : {
- "definition" : {
- "val" : "Temporal subdivision of adulthood in days post-eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2010-09-29T12:28:05Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "djs93"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "adult age in days"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007013",
- "meta" : {
- "definition" : {
- "val" : "Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2010-09-29T12:25:36Z"
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- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "djs93"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "age"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007134",
- "meta" : {
- "definition" : {
- "val" : "59th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1390." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 59 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00000054",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 1-4.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 25." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "cleavage stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007009",
- "meta" : {
- "xrefs" : [ {
- "val" : "GO:0032502"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "djs93"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2009-10-01T05:56:42Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "developmental process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007008",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "occurrent"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007129",
- "meta" : {
- "definition" : {
- "val" : "54th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1340." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 54 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007007",
- "meta" : {
- "definition" : {
- "val" : "Third instar larva from the beginning of wandering to the beginning of puparium formation.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 450." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-12-11T01:19:53Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "late third instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007128",
- "meta" : {
- "definition" : {
- "val" : "53rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1330." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 53 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007127",
- "meta" : {
- "definition" : {
- "val" : "52nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1320." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 52 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007006",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10250." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-11-13T06:27:57Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13E"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00004450",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 11 and 12.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 300." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "late extended germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005300",
- "meta" : {
- "definition" : {
- "val" : "The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 130." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005412",
- "meta" : {
- "comments" : [ "This should be considered as a type of cell rather than as a stage. Please use FBbt:00005412." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "gamete"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "type" : "PROPERTY",
- "lbl" : "shorthand"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasScope",
- "type" : "PROPERTY",
- "lbl" : "has_scope"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005280",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which 9-11 nurse cell nuclei remain at the anterior of the oocyte. During this stage, the nuclear membrane of the oocyte nucleus disappears, indicating the start of meiotic pro-metaphase.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10220. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005281",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which only 7-8 nurse cell nuclei remain at the anterior of the oocyte. At the beginning of this stage, oocyte chromosome bivalents separate from each other - indicating mid-prometaphase of oocyte meiosis.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10230." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13C"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007100",
- "meta" : {
- "definition" : {
- "val" : "25th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1050." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 25 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005284",
- "meta" : {
- "definition" : {
- "val" : "Secretion and formation of the outer endochorionic network by throughout the follicle. Crystallization of the innermost chorionic layer of the main body follicle cells.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10270." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S14A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00006011",
- "meta" : {
- "definition" : {
- "val" : "The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355", "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 625." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005285",
- "meta" : {
- "definition" : {
- "val" : "Secretion of the exochorion begins and ends.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10280." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S14B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005282",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10240." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13D"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005283",
- "meta" : {
- "definition" : {
- "val" : "The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10260." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005288",
- "meta" : {
- "comments" : [ "Temporal ordering number - 10." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "fertilized egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007104",
- "meta" : {
- "definition" : {
- "val" : "29th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1090." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 29 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005289",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from fertilization to hatching.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 20." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007103",
- "meta" : {
- "definition" : {
- "val" : "28th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1080." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 28 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007102",
- "meta" : {
- "definition" : {
- "val" : "27th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1070." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 27 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00006012",
- "meta" : {
- "definition" : {
- "val" : "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 800." ],
- "synonyms" : [ {
- "pred" : "hasRelatedSynonym",
- "val" : "adult stage III",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "FBdv:00005375"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "adult stage A3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005286",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.",
- "xrefs" : [ "FlyBase:FBrf0064779" ]
- },
- "comments" : [ "Temporal ordering number - 10290." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005287",
- "meta" : {
- "comments" : [ "Temporal ordering number - 10300." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "unfertilized egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007101",
- "meta" : {
- "definition" : {
- "val" : "26th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1060." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 26 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005279",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00018001",
- "meta" : {
- "comments" : [ "Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO." ],
- "xrefs" : [ {
- "val" : "FBdv:00018001"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "substage_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "substage_of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/IAO_0000115",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "definition"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000051",
- "meta" : {
- "definition" : {
- "val" : "a core relation that holds between a whole and its part",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
- "xrefs" : [ {
- "val" : "OBO_REL:has_part"
- }, {
- "val" : "BFO:0000051"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "has_part"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "has_part"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this year has part this day (occurrent parthood)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my body has part my brain (continuant parthood, two material entities)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "has part"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has_part"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005270",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10100." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005273",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0043885", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10130." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005274",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0043885", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10160." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005271",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074" ]
- },
- "comments" : [ "Temporal ordering number - 10110." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005272",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10120." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005277",
- "meta" : {
- "definition" : {
- "val" : "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.",
- "xrefs" : [ "FlyBase:FBrf0021038" ]
- },
- "comments" : [ "Temporal ordering number - 10190." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12C"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005278",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0029744", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10200." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005275",
- "meta" : {
- "definition" : {
- "val" : "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10170." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005276",
- "meta" : {
- "definition" : {
- "val" : "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10180." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005268",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10080." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005269",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10090." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S9"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym",
- "type" : "PROPERTY",
- "lbl" : "has_narrow_synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007001",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 490. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head an expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage." ],
- "synonyms" : [ {
- "pred" : "hasBroadSynonym",
- "val" : "metamorphosis",
- "xrefs" : [ ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "pupal stage",
- "xrefs" : [ ]
- } ],
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-06-05T04:51:40Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "P-stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007122",
- "meta" : {
- "definition" : {
- "val" : "47th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1270." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 47 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007000",
- "meta" : {
- "comments" : [ "Temporal ordering number - 20000." ],
- "xrefs" : [ {
- "val" : "GO:0007283"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
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- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-06-05T04:51:08Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "spermatogenesis"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007121",
- "meta" : {
- "definition" : {
- "val" : "46th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1260." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 46 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007120",
- "meta" : {
- "definition" : {
- "val" : "45th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1250." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 45 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007005",
- "meta" : {
- "definition" : {
- "val" : "The anterior spiracles are fully everted, with 7-9 finger-like projections. The body shortens, withdrawing three apparent abdominal segments and the larva sticks to its substrate.",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- },
- "comments" : [ "Temporal ordering number - 480." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "spiracles everted larva",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "white prepupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "third instar larval stage L2"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007126",
- "meta" : {
- "definition" : {
- "val" : "51st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1310." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 51 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007125",
- "meta" : {
- "definition" : {
- "val" : "50th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1300." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 50 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007004",
- "meta" : {
- "definition" : {
- "val" : "Stage which begins when wandering third instar larva stops crawling. The larva everts its anterior spiracles during this stage.",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- },
- "comments" : [ "Temporal ordering number - 470." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "third instar larval stage L1"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007124",
- "meta" : {
- "definition" : {
- "val" : "49th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1290." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 49 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007003",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when endochorion begins to form at the anterior pole, a process which includes the beginning of formation of the dorsal appendages. During this stage, the follicle cells secrete membranous vesicles that form irregular extracellular plaques. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10150." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S11b"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007123",
- "meta" : {
- "definition" : {
- "val" : "48th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1280." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 48 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007002",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins and ends when the dorsal appendages begin to form.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10140." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S11a"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007119",
- "meta" : {
- "definition" : {
- "val" : "44th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1240." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
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- "type" : "CLASS",
- "lbl" : "day 44 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007118",
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- "definition" : {
- "val" : "43rd day after eclosion.",
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- },
- "comments" : [ "Temporal ordering number - 1230." ],
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- "type" : "CLASS",
- "lbl" : "day 43 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00004886",
- "meta" : {
- "comments" : [ "Temporal ordering number - 10000." ],
- "xrefs" : [ {
- "val" : "GO:0048477"
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- "val" : "oogenesis stage",
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- "type" : "CLASS",
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007117",
- "meta" : {
- "definition" : {
- "val" : "42nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1220." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "day 42 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007116",
- "meta" : {
- "definition" : {
- "val" : "41st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1210." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "day 41 of adulthood"
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- "id" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "id" : "http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion",
- "type" : "PROPERTY",
- "lbl" : "has_obo_format_version"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00014201",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 9 and 10.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 270." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "type" : "CLASS",
- "lbl" : "early extended germ band stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005291",
- "meta" : {
- "definition" : {
- "val" : "The embryonic stage that lasts from the end of fertilization to the end of the second nuclear division. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0064779", "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 40." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "embryonic stage 1"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005292",
- "meta" : {
- "definition" : {
- "val" : "The first mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 50." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 1"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005290",
- "meta" : {
- "definition" : {
- "val" : "Embryonic stage 1-3.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 30." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pre-blastoderm",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "pre-blastoderm stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007111",
- "meta" : {
- "definition" : {
- "val" : "36th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1160." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "type" : "CLASS",
- "lbl" : "day 36 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005295",
- "meta" : {
- "definition" : {
- "val" : "The third mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 80." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005296",
- "meta" : {
- "definition" : {
- "val" : "The fourth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 90." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 4"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007110",
- "meta" : {
- "definition" : {
- "val" : "35th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1150." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "type" : "CLASS",
- "lbl" : "day 35 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005293",
- "meta" : {
- "definition" : {
- "val" : "Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 70." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "type" : "CLASS",
- "lbl" : "embryonic stage 2"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005294",
- "meta" : {
- "definition" : {
- "val" : "The second mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 60." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 2"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007115",
- "meta" : {
- "definition" : {
- "val" : "40th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1200." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 40 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005299",
- "meta" : {
- "definition" : {
- "val" : "The seventh mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 120." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007114",
- "meta" : {
- "definition" : {
- "val" : "39th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1190." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 39 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007113",
- "meta" : {
- "definition" : {
- "val" : "38th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1180." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 38 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005297",
- "meta" : {
- "definition" : {
- "val" : "The fifth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 100." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007112",
- "meta" : {
- "definition" : {
- "val" : "37th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1170." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 37 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005298",
- "meta" : {
- "definition" : {
- "val" : "The sixth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 110." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 6"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007108",
- "meta" : {
- "definition" : {
- "val" : "33rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1130." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 33 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007107",
- "meta" : {
- "definition" : {
- "val" : "32nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1120." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
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- "type" : "CLASS",
- "lbl" : "day 32 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007106",
- "meta" : {
- "definition" : {
- "val" : "31st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1110." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 31 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007105",
- "meta" : {
- "definition" : {
- "val" : "30th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1100." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 30 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007109",
- "meta" : {
- "definition" : {
- "val" : "34th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1140." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "lbl" : "day 34 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/BFO_0000062",
- "meta" : {
- "definition" : {
- "val" : "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
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- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
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- "val" : "BFO:0000062"
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- "basicPropertyValues" : [ {
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- "val" : "is preceded by"
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- "pred" : "http://purl.org/dc/elements/1.1/source",
- "val" : "http://www.obofoundry.org/ro/#OBO_REL:preceded_by"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "preceded by"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "preceded_by"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "preceded_by"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "preceded_by"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule",
- "type" : "PROPERTY",
- "lbl" : "namespace-id-rule"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002092",
- "meta" : {
- "comments" : [ "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology" ],
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- "val" : "happens_during"
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- "val" : "d"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "during"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "happens during"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002090",
- "meta" : {
- "comments" : [ "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "xrefs" : [ {
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "ends_at_start_of"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "ends_at_start_of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "meets"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "immediately precedes"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005361",
- "meta" : {
- "definition" : {
- "val" : "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 690." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "lbl" : "pharate adult stage P12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005362",
- "meta" : {
- "definition" : {
- "val" : "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 700." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12(i)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "wing tips grey stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "pharate adult stage P12(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005360",
- "meta" : {
- "definition" : {
- "val" : "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 680." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "thoracic bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11(ii)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005365",
- "meta" : {
- "definition" : {
- "val" : "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 730." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P14",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "mature bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005366",
- "meta" : {
- "definition" : {
- "val" : "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 740." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P15",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005363",
- "meta" : {
- "definition" : {
- "val" : "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 710." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "wings grey stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12(ii)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P12(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005364",
- "meta" : {
- "definition" : {
- "val" : "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 720." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P13",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "wings black stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005358",
- "meta" : {
- "definition" : {
- "val" : "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 660." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005359",
- "meta" : {
- "definition" : {
- "val" : "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 670." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11(i)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "head bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005356",
- "meta" : {
- "definition" : {
- "val" : "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 640." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "amber-eyed stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P9",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005357",
- "meta" : {
- "definition" : {
- "val" : "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 650." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P10",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "red-eye bald stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_root_00000000",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0100001",
- "val" : "http://purl.obolibrary.org/obo/FBdv_00000000"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000231",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000227"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007092",
- "meta" : {
- "definition" : {
- "val" : "17th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 970." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 17 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007091",
- "meta" : {
- "definition" : {
- "val" : "16th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 960." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 16 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007090",
- "meta" : {
- "definition" : {
- "val" : "15th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 950." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 15 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007096",
- "meta" : {
- "definition" : {
- "val" : "21st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1010." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 21 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007095",
- "meta" : {
- "definition" : {
- "val" : "20th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1000." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 20 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007094",
- "meta" : {
- "definition" : {
- "val" : "19th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 990." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 19 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007093",
- "meta" : {
- "definition" : {
- "val" : "18th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 980." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 18 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005350",
- "meta" : {
- "definition" : {
- "val" : "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 580." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007099",
- "meta" : {
- "definition" : {
- "val" : "24th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1040." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 24 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005351",
- "meta" : {
- "definition" : {
- "val" : "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 590." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "Malpighian tubules migrating",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007098",
- "meta" : {
- "definition" : {
- "val" : "23rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1030." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 23 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007097",
- "meta" : {
- "definition" : {
- "val" : "22nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1020." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 22 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005354",
- "meta" : {
- "definition" : {
- "val" : "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 620." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "yellow body stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005355",
- "meta" : {
- "definition" : {
- "val" : "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 630." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "yellow-eyed stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P8",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005352",
- "meta" : {
- "definition" : {
- "val" : "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 600." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "white Malpighian tubules stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005353",
- "meta" : {
- "definition" : {
- "val" : "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 610." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "green Malpighian tubules stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P6"
- }, {
- "id" : "http://purl.obolibrary.org/obo/fbdv#systematic_synonym",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasScope",
- "val" : "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "Systematic synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002087",
- "meta" : {
- "comments" : [ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" ],
- "xrefs" : [ {
- "val" : "RO:0002087"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "starts_at_end_of"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "immediately_preceded_by"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "immediately_preceded_by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005347",
- "meta" : {
- "definition" : {
- "val" : "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 550." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "buoyant stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P4(i)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
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- "val" : "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).",
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- "val" : "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 530." ],
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- "val" : "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).",
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- "val" : "Oogenesis stage that begins when the cyst leaves the germarium (from this point the cyst is referred to as an egg chamber). During this stage, polyploidation of the nurse cells begins, they reach a ploidy of 8C, and follicle cells start to divide.",
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- "val" : "Oogenesis stage that begins when the oocyte chromosomes condense into a karyosome attached to a distinctive spherical structure known as an endobody. The oocyte nucleolus disappears completely. During this stage, nurse cell ploidy reaches 16C.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
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- "comments" : [ "Temporal ordering number - 10030." ],
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- "comments" : [ "Temporal ordering number - 10010." ],
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- "val" : "Oogenesis stage during which follicle cell division ceases.",
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- "definition" : {
- "val" : "Oogenesis stage during which polyploidation and enlargement of follicle cells begins. Nurse cell ploidy ranges from 256C (anterior) to 512C (posterior) and the egg chamber gains an elongated shape.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
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- "comments" : [ "Temporal ordering number - 10070." ],
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- "meta" : {
- "definition" : {
- "val" : "The life of an individual of the species Drosophila melanogaster, from fertilization to death.",
- "xrefs" : [ "FBC:DOS" ]
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- "val" : "Drosophila life cycle",
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- "val" : "Oogenesis stage that begins when the nurse cells chromosomes become bulbous. Nurse cell chromosomes during this stage are polytene and reach a ploidy of 32C. The egg chamber is oval shaped.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
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- "meta" : {
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- "val" : "Oogenesis stage that begins when nurse cell chromosomes are no longer bulbous - the association between homologs weakens so that these chromosomes no longer have a polytene structure. During this stage, posterior nurse cell nuclei have a higher ploidy (64C) than anterior ones.",
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- "comments" : [ "Temporal ordering number - 10050." ],
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- "lbl" : "oogenesis stage S5"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005259",
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- "type" : "CLASS",
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- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 785. The time at which eclosed flies settle down for wing expansion can vary greatly. If they fail to find a suitable site then expansion can be delayed by several hours." ],
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- "comments" : [ "Temporal ordering number - 790." ],
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+ "val": "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has_part"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "has_part"
+ }
+ ],
+ "definition": {
+ "val": "a core relation that holds between a whole and its part",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000051"
+ },
+ {
+ "val": "OBO_REL:has_part"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000062",
+ "lbl": "preceded_by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "preceded by"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "is preceded by"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "preceded_by"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/source",
+ "val": "http://www.obofoundry.org/ro/#OBO_REL:preceded_by"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "preceded_by"
+ }
+ ],
+ "definition": {
+ "val": "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000062"
+ },
+ {
+ "val": "OBO_REL:preceded_by"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00000000",
+ "lbl": "Drosophila life",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv_root:00000000"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The life of an individual of the species Drosophila melanogaster, from fertilization to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "Drosophila life cycle",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00000054",
+ "lbl": "cleavage stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 25."
+ ],
+ "definition": {
+ "val": "A collective term for stages 1-4.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00004450",
+ "lbl": "late extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 300."
+ ],
+ "definition": {
+ "val": "A collective term for stages 11 and 12.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00004886",
+ "lbl": "oogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10000."
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "oogenesis stage",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0048477"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005259",
+ "lbl": "developmental stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:56:56Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00007010"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A temporal subdivision of a developmental process.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005261",
+ "lbl": "oogenesis stage S1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10010."
+ ],
+ "definition": {
+ "val": "Earliest stage of ovarian cyst development - lasts while the 16 cell cyst is within the germarium (region 3).",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005262",
+ "lbl": "oogenesis stage S2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10020."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the cyst leaves the germarium (from this point the cyst is referred to as an egg chamber). During this stage, polyploidation of the nurse cells begins, they reach a ploidy of 8C, and follicle cells start to divide.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005263",
+ "lbl": "oogenesis stage S3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10030."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the oocyte chromosomes condense into a karyosome attached to a distinctive spherical structure known as an endobody. The oocyte nucleolus disappears completely. During this stage, nurse cell ploidy reaches 16C.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005264",
+ "lbl": "oogenesis stage S4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10040."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the nurse cells chromosomes become bulbous. Nurse cell chromosomes during this stage are polytene and reach a ploidy of 32C. The egg chamber is oval shaped.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005265",
+ "lbl": "oogenesis stage S5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10050."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell chromosomes are no longer bulbous - the association between homologs weakens so that these chromosomes no longer have a polytene structure. During this stage, posterior nurse cell nuclei have a higher ploidy (64C) than anterior ones.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005266",
+ "lbl": "oogenesis stage S6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10060."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which follicle cell division ceases.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005267",
+ "lbl": "oogenesis stage S7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10070."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which polyploidation and enlargement of follicle cells begins. Nurse cell ploidy ranges from 256C (anterior) to 512C (posterior) and the egg chamber gains an elongated shape.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005268",
+ "lbl": "oogenesis stage S8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10080."
+ ],
+ "definition": {
+ "val": "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005269",
+ "lbl": "oogenesis stage S9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10090."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005270",
+ "lbl": "oogenesis stage S10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10100."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005271",
+ "lbl": "oogenesis stage S10A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10110."
+ ],
+ "definition": {
+ "val": "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005272",
+ "lbl": "oogenesis stage S10B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10120."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005273",
+ "lbl": "oogenesis stage S11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10130."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0043885",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005274",
+ "lbl": "oogenesis stage S12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10160."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0043885",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005275",
+ "lbl": "oogenesis stage S12A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10170."
+ ],
+ "definition": {
+ "val": "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005276",
+ "lbl": "oogenesis stage S12B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10180."
+ ],
+ "definition": {
+ "val": "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005277",
+ "lbl": "oogenesis stage S12C",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10190."
+ ],
+ "definition": {
+ "val": "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.",
+ "xrefs": [
+ "FlyBase:FBrf0021038"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005278",
+ "lbl": "oogenesis stage S13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10200."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0029744",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005279",
+ "lbl": "oogenesis stage S13A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005280",
+ "lbl": "oogenesis stage S13B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10220. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which 9-11 nurse cell nuclei remain at the anterior of the oocyte. During this stage, the nuclear membrane of the oocyte nucleus disappears, indicating the start of meiotic pro-metaphase.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005281",
+ "lbl": "oogenesis stage S13C",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10230."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which only 7-8 nurse cell nuclei remain at the anterior of the oocyte. At the beginning of this stage, oocyte chromosome bivalents separate from each other - indicating mid-prometaphase of oocyte meiosis.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005282",
+ "lbl": "oogenesis stage S13D",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10240."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005283",
+ "lbl": "oogenesis stage S14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10260."
+ ],
+ "definition": {
+ "val": "The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005284",
+ "lbl": "oogenesis stage S14A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10270."
+ ],
+ "definition": {
+ "val": "Secretion and formation of the outer endochorionic network by throughout the follicle. Crystallization of the innermost chorionic layer of the main body follicle cells.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005285",
+ "lbl": "oogenesis stage S14B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10280."
+ ],
+ "definition": {
+ "val": "Secretion of the exochorion begins and ends.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005286",
+ "lbl": "egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10290."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.",
+ "xrefs": [
+ "FlyBase:FBrf0064779"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005287",
+ "lbl": "unfertilized egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10300."
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005288",
+ "lbl": "fertilized egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10."
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005289",
+ "lbl": "embryonic stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 20."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from fertilization to hatching.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005290",
+ "lbl": "pre-blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 30."
+ ],
+ "definition": {
+ "val": "Embryonic stage 1-3.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pre-blastoderm",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005291",
+ "lbl": "embryonic stage 1",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 40."
+ ],
+ "definition": {
+ "val": "The embryonic stage that lasts from the end of fertilization to the end of the second nuclear division. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0064779",
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005292",
+ "lbl": "embryonic cycle 1",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 50."
+ ],
+ "definition": {
+ "val": "The first mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005293",
+ "lbl": "embryonic stage 2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 70."
+ ],
+ "definition": {
+ "val": "Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005294",
+ "lbl": "embryonic cycle 2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 60."
+ ],
+ "definition": {
+ "val": "The second mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005295",
+ "lbl": "embryonic cycle 3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 80."
+ ],
+ "definition": {
+ "val": "The third mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005296",
+ "lbl": "embryonic cycle 4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 90."
+ ],
+ "definition": {
+ "val": "The fourth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005297",
+ "lbl": "embryonic cycle 5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 100."
+ ],
+ "definition": {
+ "val": "The fifth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005298",
+ "lbl": "embryonic cycle 6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 110."
+ ],
+ "definition": {
+ "val": "The sixth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005299",
+ "lbl": "embryonic cycle 7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 120."
+ ],
+ "definition": {
+ "val": "The seventh mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005300",
+ "lbl": "embryonic cycle 8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 130."
+ ],
+ "definition": {
+ "val": "The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005301",
+ "lbl": "embryonic stage 3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 140."
+ ],
+ "definition": {
+ "val": "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005302",
+ "lbl": "embryonic cycle 9",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 150."
+ ],
+ "definition": {
+ "val": "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005303",
+ "lbl": "embryonic cycle 10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 180."
+ ],
+ "definition": {
+ "val": "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005304",
+ "lbl": "blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 160."
+ ],
+ "definition": {
+ "val": "Embryonic stages 4 and 5.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "blastoderm",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005305",
+ "lbl": "syncytial blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005306",
+ "lbl": "embryonic stage 4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 170."
+ ],
+ "definition": {
+ "val": "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "syncytial blastoderm",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "syncytial blastoderm stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005307",
+ "lbl": "embryonic cycle 11",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 185."
+ ],
+ "definition": {
+ "val": "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005308",
+ "lbl": "embryonic cycle 12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 190."
+ ],
+ "definition": {
+ "val": "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005309",
+ "lbl": "embryonic cycle 13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 200."
+ ],
+ "definition": {
+ "val": "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005310",
+ "lbl": "cellular blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005311",
+ "lbl": "embryonic stage 5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 210."
+ ],
+ "definition": {
+ "val": "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular blastoderm",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular blastoderm stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005312",
+ "lbl": "embryonic cycle 14",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "FlyBase:FBrf0049535",
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "first blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005313",
+ "lbl": "embryonic cycle 14A",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 256."
+ ],
+ "definition": {
+ "val": "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "[FlyBase:FBrf0039741"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonic cycle 14 interphase",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005314",
+ "lbl": "embryonic cycle 14B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "FlyBase:FBrf0039741"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonic cycle 14 M-phase",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005315",
+ "lbl": "embryonic cycle 15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 15th cell cycle of embryogenesis. Asynchronous.",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "second blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005316",
+ "lbl": "embryonic cycle 16",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 16th cell cycle division of embryogenesis. Asynchronous.",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "third blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005317",
+ "lbl": "gastrula stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 220."
+ ],
+ "definition": {
+ "val": "Stages during which gastrulation occurs. 6-8.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "gastrula",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005318",
+ "lbl": "embryonic stage 6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 230."
+ ],
+ "definition": {
+ "val": "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005319",
+ "lbl": "embryonic stage 7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 240."
+ ],
+ "definition": {
+ "val": "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005320",
+ "lbl": "germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005321",
+ "lbl": "extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 260."
+ ],
+ "definition": {
+ "val": "Stages during which the germ band is extended - 9-12.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005322",
+ "lbl": "embryonic stage 8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 250."
+ ],
+ "definition": {
+ "val": "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "rapidly extending germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005323",
+ "lbl": "embryonic stage 9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 280."
+ ],
+ "definition": {
+ "val": "Stage 9 begins when mesodermal segmentation becomes (transiently) visible\\, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005324",
+ "lbl": "embryonic stage 10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 290."
+ ],
+ "definition": {
+ "val": "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005325",
+ "lbl": "embryonic stage 11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 310."
+ ],
+ "definition": {
+ "val": "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005326",
+ "lbl": "contracted germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005327",
+ "lbl": "embryonic stage 12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 320."
+ ],
+ "definition": {
+ "val": "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "retracting germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005328",
+ "lbl": "embryonic stage 13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 340."
+ ],
+ "definition": {
+ "val": "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "contracted germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005329",
+ "lbl": "head involution stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "FBdv:00005330"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005330",
+ "lbl": "embryonic stage 14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 350."
+ ],
+ "definition": {
+ "val": "Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "head involution stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005331",
+ "lbl": "dorsal closure stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 330."
+ ],
+ "definition": {
+ "val": "A collective term for stages 13-15.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005332",
+ "lbl": "embryonic stage 15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 360."
+ ],
+ "definition": {
+ "val": "Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005333",
+ "lbl": "late embryonic stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 370."
+ ],
+ "definition": {
+ "val": "Embryonic stages 16-17.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005334",
+ "lbl": "embryonic stage 16",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 380."
+ ],
+ "definition": {
+ "val": "Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005335",
+ "lbl": "embryonic stage 17",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 390."
+ ],
+ "definition": {
+ "val": "Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005336",
+ "lbl": "larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 400."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005337",
+ "lbl": "first instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 410."
+ ],
+ "definition": {
+ "val": "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L1",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "first instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000000"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005338",
+ "lbl": "second instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 420."
+ ],
+ "definition": {
+ "val": "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L2",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "second instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000001"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005339",
+ "lbl": "third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 430."
+ ],
+ "definition": {
+ "val": "The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L3",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "third instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000002"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005340",
+ "lbl": "early third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T11:51:56Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 440."
+ ],
+ "definition": {
+ "val": "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005341",
+ "lbl": "wandering third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T11:55:46Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 460."
+ ],
+ "definition": {
+ "val": "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "late third instar",
+ "xrefs": []
+ },
+ {
+ "pred": "hasBroadSynonym",
+ "val": "post-feeding larva",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005342",
+ "lbl": "prepupal stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 500."
+ ],
+ "definition": {
+ "val": "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005343",
+ "lbl": "prepupal stage P1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 510."
+ ],
+ "definition": {
+ "val": "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P1",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "puparium formation",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "white puparium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "pupal stage P0",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "white prepupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005344",
+ "lbl": "prepupal stage P2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 520."
+ ],
+ "definition": {
+ "val": "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "brown puparium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P2",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005345",
+ "lbl": "prepupal stage P3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 530."
+ ],
+ "definition": {
+ "val": "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "bubble prepupa stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P3",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005346",
+ "lbl": "prepupal stage P4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 540."
+ ],
+ "definition": {
+ "val": "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cryptocephalic pupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005347",
+ "lbl": "prepupal stage P4(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 550."
+ ],
+ "definition": {
+ "val": "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "buoyant stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005348",
+ "lbl": "prepupal stage P4(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 560."
+ ],
+ "definition": {
+ "val": "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "moving bubble stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4(ii)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005349",
+ "lbl": "pupal stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 570. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for Cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head and expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage."
+ ],
+ "definition": {
+ "val": "The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "phanerocephalic pupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005350",
+ "lbl": "pupal stage P5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 580."
+ ],
+ "definition": {
+ "val": "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005351",
+ "lbl": "pupal stage P5(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 590."
+ ],
+ "definition": {
+ "val": "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "Malpighian tubules migrating",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005352",
+ "lbl": "pupal stage P5(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 600."
+ ],
+ "definition": {
+ "val": "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "white Malpighian tubules stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005353",
+ "lbl": "pupal stage P6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 610."
+ ],
+ "definition": {
+ "val": "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "green Malpighian tubules stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005354",
+ "lbl": "pupal stage P7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 620."
+ ],
+ "definition": {
+ "val": "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "yellow body stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005355",
+ "lbl": "pharate adult stage P8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 630."
+ ],
+ "definition": {
+ "val": "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P8",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "yellow-eyed stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005356",
+ "lbl": "pharate adult stage P9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 640."
+ ],
+ "definition": {
+ "val": "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "amber-eyed stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P9",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005357",
+ "lbl": "pharate adult stage P10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 650."
+ ],
+ "definition": {
+ "val": "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P10",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "red-eye bald stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005358",
+ "lbl": "pharate adult stage P11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 660."
+ ],
+ "definition": {
+ "val": "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005359",
+ "lbl": "pharate adult stage P11(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 670."
+ ],
+ "definition": {
+ "val": "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "head bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005360",
+ "lbl": "pharate adult stage P11(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 680."
+ ],
+ "definition": {
+ "val": "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11(ii)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "thoracic bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005361",
+ "lbl": "pharate adult stage P12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 690."
+ ],
+ "definition": {
+ "val": "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005362",
+ "lbl": "pharate adult stage P12(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 700."
+ ],
+ "definition": {
+ "val": "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12(i)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wing tips grey stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005363",
+ "lbl": "pharate adult stage P12(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 710."
+ ],
+ "definition": {
+ "val": "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12(ii)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wings grey stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005364",
+ "lbl": "pharate adult stage P13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 720."
+ ],
+ "definition": {
+ "val": "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P13",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wings black stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005365",
+ "lbl": "pharate adult stage P14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 730."
+ ],
+ "definition": {
+ "val": "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "mature bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P14",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005366",
+ "lbl": "pharate adult stage P15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 740."
+ ],
+ "definition": {
+ "val": "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005367",
+ "lbl": "pharate adult stage P15(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 750."
+ ],
+ "definition": {
+ "val": "Tanning of the tergites obscures the Malpighian tubules and the 'yellow body'. Legs begin to twitch; fly is able to walk if puparium is removed prematurely. Ptilinum expands by hydrostatic pressure, opening the operculum. Duration at 25 degrees C: approximately 8 hours, 6 minutes. (211.5-219.6 hours after egg laying; 91.5-99.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "meconium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005368",
+ "lbl": "pharate adult stage P15(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 760."
+ ],
+ "definition": {
+ "val": "Stage which starts when the operculum opens and ends when eclosion is completed. Duration at 25 degrees C: approximately 24 minutes. (219.6-220 hours after egg laying; 99.6-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "eclosion stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15(ii)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005369",
+ "lbl": "adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 770."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from eclosion to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005370",
+ "lbl": "adult stage A1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005373"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 785. The time at which eclosed flies settle down for wing expansion can vary greatly. If they fail to find a suitable site then expansion can be delayed by several hours."
+ ],
+ "definition": {
+ "val": "Newly eclosed adult stage. Animal free of pupal case. Runs rapidly to find site for wing expansion. Wings are folded back and black against a very pale abdomen.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage I",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005371",
+ "lbl": "adult stage A2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005374"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 790."
+ ],
+ "definition": {
+ "val": "Stage, shortly after eclosion, during which the wings expand. During wing expansion, the abdomen pulsates and the hind legs stroke the wings vigorously for several minutes at a time. The stage ends when the wings are folded down over the abdomen, which has become broader and shorter, and the wing cuticle has lost its folds. The stage lasts around 15 minutes at 25'C.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage II",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005412",
+ "lbl": "gamete",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "This should be considered as a type of cell rather than as a stage. Please use FBbt:00005412."
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00006011",
+ "lbl": "pharate adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 625."
+ ],
+ "definition": {
+ "val": "The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355",
+ "FlyBase:FBrf0049147"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00006012",
+ "lbl": "adult stage A3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005375"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 800."
+ ],
+ "definition": {
+ "val": "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage III",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007000",
+ "lbl": "spermatogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-06-05T04:51:08Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 20000."
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0007283"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007001",
+ "lbl": "P-stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-06-05T04:51:40Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 490. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head an expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "metamorphosis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "pupal stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007002",
+ "lbl": "oogenesis stage S11a",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10140."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins and ends when the dorsal appendages begin to form.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007003",
+ "lbl": "oogenesis stage S11b",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10150."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when endochorion begins to form at the anterior pole, a process which includes the beginning of formation of the dorsal appendages. During this stage, the follicle cells secrete membranous vesicles that form irregular extracellular plaques. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007004",
+ "lbl": "third instar larval stage L1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 470."
+ ],
+ "definition": {
+ "val": "Stage which begins when wandering third instar larva stops crawling. The larva everts its anterior spiracles during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007005",
+ "lbl": "third instar larval stage L2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 480."
+ ],
+ "definition": {
+ "val": "The anterior spiracles are fully everted, with 7-9 finger-like projections. The body shortens, withdrawing three apparent abdominal segments and the larva sticks to its substrate.",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "spiracles everted larva",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "white prepupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007006",
+ "lbl": "oogenesis stage S13E",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T06:27:57Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10250."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007007",
+ "lbl": "late third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-12-11T01:19:53Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 450."
+ ],
+ "definition": {
+ "val": "Third instar larva from the beginning of wandering to the beginning of puparium formation.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007008",
+ "lbl": "occurrent",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007009",
+ "lbl": "developmental process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:56:42Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0032502"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007011",
+ "lbl": "embryonic cycle",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:57:41Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.",
+ "xrefs": [
+ "FlyBase:FBrf0049535",
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007012",
+ "lbl": "life stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "djs93"
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:59:22Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "life cycle stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007013",
+ "lbl": "age",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-29T12:25:36Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007014",
+ "lbl": "adult age in days",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-29T12:28:05Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Temporal subdivision of adulthood in days post-eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007015",
+ "lbl": "embryonic stage 17(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T11:57:15Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007016",
+ "lbl": "embryonic stage 17(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:00:15Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 392. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007017",
+ "lbl": "embryonic stage 17(iii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:01:18Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 393. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007018",
+ "lbl": "embryonic stage 17(iv)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:03:14Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 394. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007019",
+ "lbl": "third instar - uncleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994)."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007020",
+ "lbl": "third instar - partially cleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994)."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007021",
+ "lbl": "third instar - cleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage when the larva has cleared its gut contents.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007022",
+ "lbl": "embryonic cycle interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The interphase (GO:0051325) of an embryonic cycle.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007023",
+ "lbl": "embryonic cycle M-phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The M-phase (GO:0000279) of an embryonic cycle.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007024",
+ "lbl": "biological process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0008150"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007025",
+ "lbl": "immature adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-01-08T20:06:59Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 782."
+ ],
+ "definition": {
+ "val": "The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007026",
+ "lbl": "mature adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-01-10T13:03:54Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Life stage from the end of adult stage A3, when tanning is complete, to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007075",
+ "lbl": "day 0 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 780."
+ ],
+ "definition": {
+ "val": "The day of eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007076",
+ "lbl": "day 1 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 810."
+ ],
+ "definition": {
+ "val": "1st day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007077",
+ "lbl": "day 2 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 820."
+ ],
+ "definition": {
+ "val": "2nd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007078",
+ "lbl": "day 3 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 830."
+ ],
+ "definition": {
+ "val": "3rd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007079",
+ "lbl": "day 4 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 840."
+ ],
+ "definition": {
+ "val": "4th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007080",
+ "lbl": "day 5 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 850."
+ ],
+ "definition": {
+ "val": "5th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007081",
+ "lbl": "day 6 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 860."
+ ],
+ "definition": {
+ "val": "6th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007082",
+ "lbl": "day 7 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 870."
+ ],
+ "definition": {
+ "val": "7th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007083",
+ "lbl": "day 8 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 880."
+ ],
+ "definition": {
+ "val": "8th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007084",
+ "lbl": "day 9 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 890."
+ ],
+ "definition": {
+ "val": "9th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007085",
+ "lbl": "day 10 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 900."
+ ],
+ "definition": {
+ "val": "10th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007086",
+ "lbl": "day 11 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 910."
+ ],
+ "definition": {
+ "val": "11th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007087",
+ "lbl": "day 12 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 920."
+ ],
+ "definition": {
+ "val": "12th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007088",
+ "lbl": "day 13 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 930."
+ ],
+ "definition": {
+ "val": "13th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007089",
+ "lbl": "day 14 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 940."
+ ],
+ "definition": {
+ "val": "14th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007090",
+ "lbl": "day 15 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 950."
+ ],
+ "definition": {
+ "val": "15th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007091",
+ "lbl": "day 16 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 960."
+ ],
+ "definition": {
+ "val": "16th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007092",
+ "lbl": "day 17 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 970."
+ ],
+ "definition": {
+ "val": "17th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007093",
+ "lbl": "day 18 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 980."
+ ],
+ "definition": {
+ "val": "18th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007094",
+ "lbl": "day 19 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 990."
+ ],
+ "definition": {
+ "val": "19th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007095",
+ "lbl": "day 20 of adulthood",
+ "meta": {
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+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1400."
+ ],
+ "definition": {
+ "val": "60th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00014201",
+ "lbl": "early extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 270."
+ ],
+ "definition": {
+ "val": "A collective term for stages 9 and 10.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00018001",
+ "lbl": "substage_of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "substage_of"
+ }
+ ],
+ "comments": [
+ "Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO."
+ ],
+ "xrefs": [
+ {
+ "val": "FBdv:00018001"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/IAO_0000115",
+ "lbl": "definition",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000122"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002012",
+ "lbl": "occurent part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "occurent_part_of"
+ }
+ ],
+ "definition": {
+ "val": "A part of relation that applies only between occurents.",
+ "xrefs": []
+ },
+ "xrefs": [
+ {
+ "val": "RO:0002012"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002087",
+ "lbl": "immediately_preceded_by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "starts_at_end_of"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "immediately_preceded_by"
+ }
+ ],
+ "comments": [
+ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002087"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002090",
+ "lbl": "immediately precedes",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "ends_at_start_of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "meets"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002575",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000063"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "ends_at_start_of"
+ }
+ ],
+ "comments": [
+ "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002090"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002092",
+ "lbl": "happens during",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "d"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "during"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "happens_during"
+ }
+ ],
+ "comments": [
+ "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002092"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002131",
+ "lbl": "overlaps",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000424",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "overlaps"
+ }
+ ],
+ "definition": {
+ "val": "x overlaps y if and only if there exists some z such that x has part z and z part of y",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002131"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/fbdv#systematic_synonym",
+ "lbl": "Systematic synonym",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasScope",
+ "val": "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "lbl": "term replaced by",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule",
+ "lbl": "namespace-id-rule",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#SubsetProperty",
+ "lbl": "subset_property",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty",
+ "lbl": "synonym_type_property",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "lbl": "has_alternative_id",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym",
+ "lbl": "has_broad_synonym",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasDbXref",
+ "lbl": "database_cross_reference",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym",
+ "lbl": "has_exact_synonym",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym",
+ "lbl": "has_narrow_synonym",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion",
+ "lbl": "has_obo_format_version",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "lbl": "has_obo_namespace",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym",
+ "lbl": "has_related_synonym",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#hasScope",
+ "lbl": "has_scope",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "lbl": "shorthand",
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005373",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000231",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000227"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00005370"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005374",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000231",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000227"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00005371"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005375",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000231",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000227"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00006012"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007010",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000231",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000227"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00005259"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_root_00000000",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000231",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000227"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00000000"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ }
+ ],
+ "propertyChainAxioms": [
+ {
+ "chainPredicateIds": [
+ "http://purl.obolibrary.org/obo/BFO_0000051",
+ "http://purl.obolibrary.org/obo/RO_0002131"
+ ],
+ "predicateId": "http://purl.obolibrary.org/obo/RO_0002131"
+ },
+ {
+ "chainPredicateIds": [
+ "http://purl.obolibrary.org/obo/BFO_0000062",
+ "http://purl.obolibrary.org/obo/RO_0002092"
+ ],
+ "predicateId": "http://purl.obolibrary.org/obo/BFO_0000062"
+ }
+ ]
+ }
+ ]
+}
diff --git a/fbdv-simple.obo b/fbdv-simple.obo
index a687f53..92df114 100644
--- a/fbdv-simple.obo
+++ b/fbdv-simple.obo
@@ -1,6 +1,6 @@
format-version: 1.2
-data-version: fbdv/releases/2021-01-13/fbdv-simple.owl
-date: 13:01:2021 12:25
+data-version: fbdv/releases/2021-03-10/fbdv-simple.owl
+date: 10:03:2021 10:38
subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation"
subsetdef: gocheck_do_not_manually_annotate "Term not to be used for direct manual annotation"
subsetdef: goslim_aspergillus "Aspergillus GO slim"
@@ -33,7 +33,7 @@ property_value: IAO:0000700 FBdv:00000000
property_value: IAO:0000700 FBdv:00005259
property_value: IAO:0000700 FBdv:00007013
property_value: IAO:0000700 FBdv:00007024
-property_value: owl:versionInfo "2021-01-13" xsd:string
+property_value: owl:versionInfo "2021-03-10" xsd:string
[Term]
id: FBdv:00000000
@@ -327,6 +327,7 @@ comment: Temporal ordering number - 10.
is_a: FBdv:00005259 ! developmental stage
relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
relationship: substage_of FBdv:00005286 ! egg stage
+relationship: substage_of FBdv:00005289 ! embryonic stage
[Term]
id: FBdv:00005289
@@ -334,7 +335,7 @@ name: embryonic stage
def: "The stage of the Drosophila life-cycle from fertilization to hatching." [FBC:DOS]
comment: Temporal ordering number - 20.
is_a: FBdv:00007012 ! life stage
-relationship: immediately_preceded_by FBdv:00005288 ! fertilized egg stage
+relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
[Term]
id: FBdv:00005290
@@ -780,6 +781,7 @@ def: "The first larval instar begins at hatching and ends at the first larval mo
comment: Temporal ordering number - 410.
synonym: "first instar larva" EXACT []
synonym: "L1" EXACT []
+xref: UBERON:8000000
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005289 ! embryonic stage
relationship: immediately_preceded_by FBdv:00005333 ! late embryonic stage
@@ -794,6 +796,7 @@ def: "The second larval instar begins at the first larval molt and ends at the s
comment: Temporal ordering number - 420.
synonym: "L2" EXACT []
synonym: "second instar larva" EXACT []
+xref: UBERON:8000001
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005337 ! first instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -805,6 +808,7 @@ def: "The third larval instar begins at the second larval molt and ends at pupar
comment: Temporal ordering number - 430.
synonym: "L3" EXACT []
synonym: "third instar larva" RELATED []
+xref: UBERON:8000002
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005338 ! second instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -2003,6 +2007,7 @@ relationship: substage_of FBdv:00005321 ! extended germ band stage
id: ends_at_start_of
name: immediately precedes
comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)
+subset: ro-eco
xref: RO:0002090
property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string
property_value: IAO:0000118 "ends_at_start_of" xsd:string
@@ -2016,6 +2021,7 @@ comment: X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X))
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
+subset: ro-eco
xref: RO:0002092
property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string
property_value: IAO:0000118 "d" xsd:string
@@ -2067,6 +2073,7 @@ name: overlaps
def: "x overlaps y if and only if there exists some z such that x has part z and z part of y" []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_gocam
+subset: ro-eco
xref: RO:0002131
property_value: IAO:0000114 IAO:0000125
property_value: RO:0001900 RO:0001901
@@ -2078,6 +2085,7 @@ id: preceded_by
name: preceded_by
namespace: relationship
def: "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." []
+subset: ro-eco
xref: BFO:0000062
xref: OBO_REL:preceded_by
property_value: http://purl.org/dc/elements/1.1/source http://www.obofoundry.org/ro/#OBO_REL:preceded_by xsd:string
@@ -2096,5 +2104,5 @@ comment: Creating this relation as a temporary fix, pending adding the axiom occ
xref: FBdv:00018001
is_transitive: true
is_a: happens_during ! happens during
-is_a: occurent_part_of ! occurent_part_of
+is_a: occurent_part_of ! occurent part of
diff --git a/fbdv-simple.owl b/fbdv-simple.owl
index 7b206ca..062cd8d 100644
--- a/fbdv-simple.owl
+++ b/fbdv-simple.owl
@@ -13,7 +13,7 @@
xmlns:subsets="http://purl.obolibrary.org/obo/ro/subsets#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
-
+
@@ -26,10 +26,10 @@
FlyBase Developmental Ontology (FBdv)
https://creativecommons.org/licenses/by/3.0/
* FBdv:$sequence(8,7000,10000)$
- 13:01:2021 12:25
+ 10:03:2021 10:38
FlyBase_development_CV
1.2
- 2021-01-13
+ 2021-03-10
@@ -287,36 +287,12 @@
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
@@ -1665,6 +1641,12 @@ A continuant cannot have an occurrent as part: use 'participates in'.
+
+
+
+
+
+
@@ -1686,7 +1668,7 @@ A continuant cannot have an occurrent as part: use 'participates in'.
-
+
The stage of the Drosophila life-cycle from fertilization to hatching.
@@ -3247,6 +3229,7 @@ A continuant cannot have an occurrent as part: use 'participates in'.
The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).
+ UBERON:8000000
L1
first instar larva
FlyBase_development_CV
@@ -3280,6 +3263,7 @@ A continuant cannot have an occurrent as part: use 'participates in'.
The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).
+ UBERON:8000001
L2
second instar larva
FlyBase_development_CV
@@ -3313,6 +3297,7 @@ A continuant cannot have an occurrent as part: use 'participates in'.
The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).
+ UBERON:8000002
L3
FlyBase_development_CV
third instar larva
diff --git a/fbdv.json b/fbdv.json
index 96772d4..86ef05a 100644
--- a/fbdv.json
+++ b/fbdv.json
@@ -1,10480 +1,14641 @@
{
- "graphs" : [ {
- "nodes" : [ {
- "id" : "http://purl.obolibrary.org/obo/GO_0003674",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "molecular process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "molecular_function"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0000280",
- "meta" : {
- "definition" : {
- "val" : "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.",
- "xrefs" : [ "GOC:mah" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ],
- "synonyms" : [ {
- "pred" : "hasRelatedSynonym",
- "val" : "karyokinesis",
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- } ],
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- "val" : "biological_process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "nuclear division"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005321",
- "meta" : {
- "definition" : {
- "val" : "Stages during which the germ band is extended - 9-12.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 260." ],
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- "val" : "FlyBase_development_CV"
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- },
- "type" : "CLASS",
- "lbl" : "extended germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005322",
- "meta" : {
- "definition" : {
- "val" : "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 250." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "rapidly extending germ band stage",
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- } ],
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- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 8"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005320",
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- },
- "type" : "CLASS",
- "lbl" : "germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005314",
- "meta" : {
- "definition" : {
- "val" : "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "FlyBase:FBrf0039741" ]
- },
- "comments" : [ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "embryonic cycle 14 M-phase",
- "xrefs" : [ "FBC:DOS" ]
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- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 14B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005315",
- "meta" : {
- "definition" : {
- "val" : "The 15th cell cycle of embryogenesis. Asynchronous.",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "second blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005312",
- "meta" : {
- "definition" : {
- "val" : "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "FlyBase:FBrf0049535", "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "first blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005313",
- "meta" : {
- "definition" : {
- "val" : "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
- "xrefs" : [ "[FlyBase:FBrf0039741" ]
- },
- "comments" : [ "Temporal ordering number - 256." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "embryonic cycle 14 interphase",
- "xrefs" : [ "FBC:DOS" ]
- } ],
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- "val" : "FlyBase_development_CV"
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- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 14A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005318",
- "meta" : {
- "definition" : {
- "val" : "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 230." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 6"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005319",
- "meta" : {
- "definition" : {
- "val" : "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 240." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005316",
- "meta" : {
- "definition" : {
- "val" : "The 16th cell cycle division of embryogenesis. Asynchronous.",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "third blastoderm mitosis",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- } ],
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 16"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005317",
- "meta" : {
- "definition" : {
- "val" : "Stages during which gastrulation occurs. 6-8.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 220." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "gastrula",
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- } ],
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- },
- "type" : "CLASS",
- "lbl" : "gastrula stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/PATO_0000001",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "quality (PATO)"
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- },
- "type" : "CLASS",
- "lbl" : "quality"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0016740",
- "type" : "CLASS",
- "lbl" : "transferase activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002608",
- "meta" : {
- "definition" : {
- "val" : "Inverse of 'causal agent in process'",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
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- },
- "type" : "PROPERTY",
- "lbl" : "process has causal agent"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002286",
- "meta" : {
- "definition" : {
- "val" : "Inverse of developmentally preceded by",
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- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
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- },
- "type" : "PROPERTY",
- "lbl" : "developmentally succeeded by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005310",
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- "val" : "FlyBase_development_CV"
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- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "cellular blastoderm stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005311",
- "meta" : {
- "definition" : {
- "val" : "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 210." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "cellular blastoderm stage",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "cellular blastoderm",
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- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0009790",
- "meta" : {
- "definition" : {
- "val" : "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.",
- "xrefs" : [ "GOC:go_curators", "GOC:isa_complete", "GOC:mtg_sensu" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate" ],
- "xrefs" : [ {
- "val" : "Wikipedia:Embryogenesis"
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- "synonyms" : [ {
- "pred" : "hasBroadSynonym",
- "val" : "embryogenesis and morphogenesis",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "embryogenesis",
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- }, {
- "pred" : "hasExactSynonym",
- "val" : "embryonal development",
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- "val" : "biological_process"
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- "val" : "GO:0009795"
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- },
- "type" : "CLASS",
- "lbl" : "embryo development"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005303",
- "meta" : {
- "definition" : {
- "val" : "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 180." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005304",
- "meta" : {
- "definition" : {
- "val" : "Embryonic stages 4 and 5.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 160." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "blastoderm",
- "xrefs" : [ ]
- } ],
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- "type" : "CLASS",
- "lbl" : "blastoderm stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005301",
- "meta" : {
- "definition" : {
- "val" : "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 140." ],
- "basicPropertyValues" : [ {
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005302",
- "meta" : {
- "definition" : {
- "val" : "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 150." ],
- "basicPropertyValues" : [ {
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- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005307",
- "meta" : {
- "definition" : {
- "val" : "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 185." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005308",
- "meta" : {
- "definition" : {
- "val" : "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 190." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 12"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005305",
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- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "syncytial blastoderm stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005306",
- "meta" : {
- "definition" : {
- "val" : "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 170." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "syncytial blastoderm stage",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
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- "type" : "CLASS",
- "lbl" : "embryonic stage 4"
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- "type" : "PROPERTY",
- "lbl" : "has_related_synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005309",
- "meta" : {
- "definition" : {
- "val" : "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
- },
- "comments" : [ "Temporal ordering number - 200." ],
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- "type" : "CLASS",
- "lbl" : "embryonic cycle 13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007081",
- "meta" : {
- "definition" : {
- "val" : "6th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 860." ],
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- "type" : "CLASS",
- "lbl" : "day 6 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007080",
- "meta" : {
- "definition" : {
- "val" : "5th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 850." ],
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- "type" : "CLASS",
- "lbl" : "day 5 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007085",
- "meta" : {
- "definition" : {
- "val" : "10th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 900." ],
- "basicPropertyValues" : [ {
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- "type" : "CLASS",
- "lbl" : "day 10 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007084",
- "meta" : {
- "definition" : {
- "val" : "9th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 890." ],
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- "type" : "CLASS",
- "lbl" : "day 9 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007083",
- "meta" : {
- "definition" : {
- "val" : "8th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 880." ],
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- "type" : "CLASS",
- "lbl" : "day 8 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007082",
- "meta" : {
- "definition" : {
- "val" : "7th day after eclosion.",
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- },
- "comments" : [ "Temporal ordering number - 870." ],
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- "val" : "14th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 940." ],
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- "lbl" : "day 14 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005340",
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- "val" : "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).",
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- "comments" : [ "Temporal ordering number - 440." ],
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-11-13T11:51:56Z"
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- "type" : "CLASS",
- "lbl" : "early third instar larval stage"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007088",
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- "definition" : {
- "val" : "13th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 930." ],
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- "type" : "CLASS",
- "lbl" : "day 13 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007087",
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- "val" : "12th day after eclosion.",
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- "comments" : [ "Temporal ordering number - 920." ],
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- "type" : "CLASS",
- "lbl" : "day 12 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00007086",
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- "val" : "11th day after eclosion.",
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- },
- "comments" : [ "Temporal ordering number - 910." ],
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- "lbl" : "day 11 of adulthood"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005343",
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- "val" : "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 510." ],
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- "val" : "pupal stage P0",
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- "pred" : "hasNarrowSynonym",
- "val" : "white prepupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
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- "pred" : "hasExactSynonym",
- "val" : "pupal stage P1",
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- "pred" : "hasExactSynonym",
- "val" : "puparium formation",
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- "pred" : "hasExactSynonym",
- "val" : "white puparium stage",
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- "lbl" : "prepupal stage P1"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005344",
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- "definition" : {
- "val" : "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 520." ],
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- "val" : "brown puparium stage",
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- "lbl" : "prepupal stage P2"
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005341",
- "meta" : {
- "definition" : {
- "val" : "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 460." ],
- "synonyms" : [ {
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- "val" : "late third instar",
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- }, {
- "pred" : "hasBroadSynonym",
- "val" : "post-feeding larva",
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- "val" : "2008-11-13T11:55:46Z"
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- "definition" : {
- "val" : "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).",
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- "comments" : [ "Temporal ordering number - 500." ],
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- "id" : "http://purl.obolibrary.org/obo/FBdv_00005336",
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- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.",
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- "comments" : [ "Temporal ordering number - 400." ],
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- "lbl" : "larval stage"
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- "val" : "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).",
- "xrefs" : [ "FlyBase:FBrf0007733" ]
- },
- "comments" : [ "Temporal ordering number - 410." ],
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- "val" : "first instar larva",
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- "val" : "Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).",
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- "comments" : [ "Temporal ordering number - 380." ],
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- "val" : "Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).",
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- "comments" : [ "Temporal ordering number - 390." ],
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- "val" : "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).",
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- "comments" : [ "Temporal ordering number - 420." ],
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- "val" : "L2",
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- "pred" : "hasExactSynonym",
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- "comments" : [ "Temporal ordering number - 430." ],
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- "id" : "http://purl.obolibrary.org/obo/RO_0002024",
- "meta" : {
- "definition" : {
- "val" : "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.",
- "xrefs" : [ "GOC:dos" ]
- },
- "basicPropertyValues" : [ {
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- "val" : "2017-09-17T13:52:47Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "dos"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "directly positively regulated by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002387",
- "meta" : {
- "definition" : {
- "val" : "x has the potential to develop into y iff x develops into y or if x is capable of developing into y",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has potential to develop into"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007076",
- "meta" : {
- "definition" : {
- "val" : "1st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 810." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 1 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002388",
- "meta" : {
- "definition" : {
- "val" : "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has potential to directly develop into"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002025",
- "meta" : {
- "definition" : {
- "val" : "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.",
- "xrefs" : [ "GOC:dos" ]
- },
- "comments" : [ "This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "dos"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2017-09-22T14:14:36Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has effector activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007075",
- "meta" : {
- "definition" : {
- "val" : "The day of eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 780." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 0 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005332",
- "meta" : {
- "definition" : {
- "val" : "Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 360." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005333",
- "meta" : {
- "definition" : {
- "val" : "Embryonic stages 16-17.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 370." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "late embryonic stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005330",
- "meta" : {
- "definition" : {
- "val" : "Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 350." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "head involution stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002384",
- "meta" : {
- "definition" : {
- "val" : "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has developmental potential involving"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002263",
- "meta" : {
- "definition" : {
- "val" : "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision."
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007079",
- "meta" : {
- "definition" : {
- "val" : "4th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 840." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 4 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005331",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 13-15.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 330." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "dorsal closure stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005325",
- "meta" : {
- "definition" : {
- "val" : "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 310." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005326",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "contracted germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005323",
- "meta" : {
- "definition" : {
- "val" : "Stage 9 begins when mesodermal segmentation becomes (transiently) visible\\, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 280." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005324",
- "meta" : {
- "definition" : {
- "val" : "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 290." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005329",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0100001",
- "val" : "FBdv:00005330"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "head involution stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002015",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.",
- "xrefs" : [ ]
- },
- "comments" : [ "By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'." ],
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2017-05-24T09:31:17Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "dos"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has positive regulatory component activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002258",
- "meta" : {
- "definition" : {
- "val" : "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p",
- "xrefs" : [ ]
- },
- "comments" : [ "This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "false"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "In general you should not use this relation to make assertions - use one of the more specific relations below this one"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "developmentally preceded by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005327",
- "meta" : {
- "definition" : {
- "val" : "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 320." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "retracting germ band stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "embryonic stage 12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002017",
- "meta" : {
- "comments" : [ "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "dos"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2017-05-24T09:44:33Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has component activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002018",
- "meta" : {
- "definition" : {
- "val" : "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
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- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2017-05-24T09:49:21Z"
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- "val" : "dos"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has component process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005328",
- "meta" : {
- "definition" : {
- "val" : "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).",
- "xrefs" : [ "FlyBase:FBrf0089570" ]
- },
- "comments" : [ "Temporal ordering number - 340." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "contracted germ band stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 13"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "type" : "PROPERTY",
- "lbl" : "has_alternative_id"
- }, {
- "id" : "http://purl.obolibrary.org/obo/CARO_0000000",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000412",
- "val" : "http://purl.obolibrary.org/obo/caro.owl"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "anatomical entity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0098763",
- "meta" : {
- "definition" : {
- "val" : "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.",
- "xrefs" : [ "GOC:dos" ]
- },
- "comments" : [ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "mitotic cell cycle phase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0011002",
- "meta" : {
- "definition" : {
- "val" : "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007023",
- "meta" : {
- "definition" : {
- "val" : "The M-phase (GO:0000279) of an embryonic cycle.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle M-phase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002254",
- "meta" : {
- "definition" : {
- "val" : "x has developmental contribution from y iff x has some part z such that z develops from y",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has developmental contribution from"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002012",
- "meta" : {
- "definition" : {
- "val" : "A part of relation that applies only between occurents.",
- "xrefs" : [ ]
- },
- "xrefs" : [ {
- "val" : "RO:0002012"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "occurent part of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007022",
- "meta" : {
- "definition" : {
- "val" : "The interphase (GO:0051325) of an embryonic cycle.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle interphase"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002013",
- "meta" : {
- "definition" : {
- "val" : "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
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- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
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- "val" : "djs93"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 17(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002481",
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- "basicPropertyValues" : [ {
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- },
- "type" : "PROPERTY",
- "lbl" : "is kinase activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007015",
- "meta" : {
- "definition" : {
- "val" : "The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "val" : "djs93"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2011-04-26T11:57:15Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage 17(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007135",
- "meta" : {
- "definition" : {
- "val" : "60th day after eclosion.",
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- },
- "comments" : [ "Temporal ordering number - 1400." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 60 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007014",
- "meta" : {
- "definition" : {
- "val" : "Temporal subdivision of adulthood in days post-eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2010-09-29T12:28:05Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "djs93"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "adult age in days"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007134",
- "meta" : {
- "definition" : {
- "val" : "59th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1390." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 59 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007013",
- "meta" : {
- "definition" : {
- "val" : "Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2010-09-29T12:25:36Z"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "djs93"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "age"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00000054",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 1-4.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 25." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "cleavage stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007009",
- "meta" : {
- "xrefs" : [ {
- "val" : "GO:0032502"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "djs93"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2009-10-01T05:56:42Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "developmental process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007008",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS",
- "lbl" : "occurrent"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007129",
- "meta" : {
- "definition" : {
- "val" : "54th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1340." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 54 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007128",
- "meta" : {
- "definition" : {
- "val" : "53rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1330." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 53 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007007",
- "meta" : {
- "definition" : {
- "val" : "Third instar larva from the beginning of wandering to the beginning of puparium formation.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 450." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-12-11T01:19:53Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "late third instar larval stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007006",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10250." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-11-13T06:27:57Z"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13E"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0000057",
- "meta" : {
- "definition" : {
- "val" : "a relation between a process and a continuant, in which the continuant is somehow involved in the process",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this process has participant this input material (or this output material)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this blood coagulation has participant this blood clot"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "has_participant"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this investigation has participant this investigator"
- }, {
- "pred" : "http://purl.org/dc/elements/1.1/source",
- "val" : "http://www.obofoundry.org/ro/#OBO_REL:has_participant"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "has participant"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has participant"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007127",
- "meta" : {
- "definition" : {
- "val" : "52nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1320." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 52 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002598",
- "meta" : {
- "definition" : {
- "val" : "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "renin -> arteriolar smooth muscle contraction"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "capable of positively regulating"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0045448",
- "meta" : {
- "definition" : {
- "val" : "The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.",
- "xrefs" : [ "GOC:go_curators" ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "mitotic cell cycle, embryonic"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002479",
- "meta" : {
- "definition" : {
- "val" : "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has part that occurs in"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0009987",
- "meta" : {
- "definition" : {
- "val" : "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",
- "xrefs" : [ "GOC:go_curators", "GOC:isa_complete" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_plant" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "cellular physiological process",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "cell physiology",
- "xrefs" : [ ]
- }, {
- "pred" : "hasNarrowSynonym",
- "val" : "cell growth and/or maintenance",
- "xrefs" : [ ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "single-organism cellular process",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "GO:0044763"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "GO:0008151"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "GO:0050875"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2012-12-11T16:56:55Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "jl"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "cellular process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0048285",
- "meta" : {
- "definition" : {
- "val" : "The creation of two or more organelles by division of one organelle.",
- "xrefs" : [ "GOC:jid" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#goslim_pir" ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "organelle fission"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002352",
- "meta" : {
- "definition" : {
- "val" : "inverse of has input",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/RO_0002259" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "input of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002595",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "causal relation between material entity and a process"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002233",
- "meta" : {
- "definition" : {
- "val" : "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
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- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "consumes"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has input"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002596",
- "meta" : {
- "definition" : {
- "val" : "Holds between c and p if and only if c is capable of some activity a, and a regulates p.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
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- "val" : "pyrethroid -> growth"
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- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "capable of regulating"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002597",
- "meta" : {
- "definition" : {
- "val" : "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.",
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- },
- "basicPropertyValues" : [ {
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- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "capable of negatively regulating"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0000056",
- "meta" : {
- "definition" : {
- "val" : "a relation between a continuant and a process, in which the continuant is somehow involved in the process",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
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- "val" : "this investigator participates in this investigation"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this input material (or this output material) participates in this process"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this blood clot participates in this blood coagulation"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "participates in"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "participates_in"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "participates in"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00004450",
- "meta" : {
- "definition" : {
- "val" : "A collective term for stages 11 and 12.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 300." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "late extended germ band stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005300",
- "meta" : {
- "definition" : {
- "val" : "The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
- "xrefs" : [ "FlyBase:FBrf0049535" ]
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- "comments" : [ "Temporal ordering number - 130." ],
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic cycle 8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005412",
- "meta" : {
- "comments" : [ "This should be considered as a type of cell rather than as a stage. Please use FBbt:00005412." ],
- "basicPropertyValues" : [ {
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- },
- "type" : "CLASS",
- "lbl" : "gamete"
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- "id" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "type" : "PROPERTY",
- "lbl" : "shorthand"
- }, {
- "id" : "http://purl.obolibrary.org/obo/CARO_0030000",
- "type" : "CLASS",
- "lbl" : "biological entity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0048856",
- "meta" : {
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- "val" : "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20123131"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "capable of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002216",
- "meta" : {
- "definition" : {
- "val" : "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "has function in"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "https://github.com/oborel/obo-relations/wiki/ROGuide#defining-property-chains-involving-reflexivity"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "capable of part of"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasScope",
- "type" : "PROPERTY",
- "lbl" : "has_scope"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005280",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which 9-11 nurse cell nuclei remain at the anterior of the oocyte. During this stage, the nuclear membrane of the oocyte nucleus disappears, indicating the start of meiotic pro-metaphase.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10220. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005281",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which only 7-8 nurse cell nuclei remain at the anterior of the oocyte. At the beginning of this stage, oocyte chromosome bivalents separate from each other - indicating mid-prometaphase of oocyte meiosis.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10230." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13C"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005284",
- "meta" : {
- "definition" : {
- "val" : "Secretion and formation of the outer endochorionic network by throughout the follicle. Crystallization of the innermost chorionic layer of the main body follicle cells.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10270." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S14A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007100",
- "meta" : {
- "definition" : {
- "val" : "25th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1050." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 25 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002331",
- "meta" : {
- "definition" : {
- "val" : "c involved_in p if and only if c enables some process p', and p' is part of p",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "enables part of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "actively involved in"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://wiki.geneontology.org/index.php/Involved_in"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "involved in"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005285",
- "meta" : {
- "definition" : {
- "val" : "Secretion of the exochorion begins and ends.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10280." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S14B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002573",
- "meta" : {
- "definition" : {
- "val" : "A relation that holds between an attribute or a qualifier and another attribute.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the \"modifiers\" are."
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has modifier"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00006011",
- "meta" : {
- "definition" : {
- "val" : "The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355", "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 625." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005282",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10240." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13D"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002211",
- "meta" : {
- "definition" : {
- "val" : "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Regulation precludes parthood; the regulatory process may not be within the regulated process."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "GO"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Hill"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000600",
- "val" : "false"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Tanya Berardini"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "regulates (processual)"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "regulates"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002212",
- "meta" : {
- "definition" : {
- "val" : "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "negatively regulates (process to process)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
- "val" : "http://purl.obolibrary.org/obo/RO_0002211"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "negatively regulates"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002333",
- "meta" : {
- "definition" : {
- "val" : "inverse of enables",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "enabled by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005283",
- "meta" : {
- "definition" : {
- "val" : "The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10260." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005288",
- "meta" : {
- "comments" : [ "Temporal ordering number - 10." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "fertilized egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007104",
- "meta" : {
- "definition" : {
- "val" : "29th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1090." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 29 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005289",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from fertilization to hatching.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 20." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "embryonic stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007103",
- "meta" : {
- "definition" : {
- "val" : "28th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1080." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 28 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007102",
- "meta" : {
- "definition" : {
- "val" : "27th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1070." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 27 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00006012",
- "meta" : {
- "definition" : {
- "val" : "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.",
- "xrefs" : [ "FlyBase:FBrf0049147" ]
- },
- "comments" : [ "Temporal ordering number - 800." ],
- "synonyms" : [ {
- "pred" : "hasRelatedSynonym",
- "val" : "adult stage III",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
- "val" : "FBdv:00005375"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "adult stage A3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005286",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.",
- "xrefs" : [ "FlyBase:FBrf0064779" ]
- },
- "comments" : [ "Temporal ordering number - 10290." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002450",
- "meta" : {
- "definition" : {
- "val" : "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.",
- "xrefs" : [ ]
- },
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "molecularly increases activity of",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "directly activates"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "directly positively regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005287",
- "meta" : {
- "comments" : [ "Temporal ordering number - 10300." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "unfertilized egg stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007101",
- "meta" : {
- "definition" : {
- "val" : "26th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1060." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 26 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002448",
- "meta" : {
- "definition" : {
- "val" : "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.",
- "xrefs" : [ ]
- },
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "molecularly controls",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "directly regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002327",
- "meta" : {
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "executes"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "catalyzes"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "a particular instances of akt-2 enables some instance of protein kinase activity"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "is catalyzing"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "is executing"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "has"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "enables"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002449",
- "meta" : {
- "definition" : {
- "val" : "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.",
- "xrefs" : [ ]
- },
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "molecularly decreases activity of",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "directly inhibits"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "directly negatively regulates activity of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002328",
- "meta" : {
- "definition" : {
- "val" : "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "This is a grouping relation that collects relations used for the purpose of connecting structure and function"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "functionally related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002329",
- "meta" : {
- "definition" : {
- "val" : "this relation holds between c and p when c is part of some c', and c' is capable of p.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "false"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "part of structure that is capable of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005279",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.",
- "xrefs" : [ "FlyBase:FBrf0029744" ]
- },
- "comments" : [ "Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000050",
- "meta" : {
- "definition" : {
- "val" : "a core relation that holds between a part and its whole",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ],
- "xrefs" : [ {
- "val" : "BFO:0000050"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "part_of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000004"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000003"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000002"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://www.obofoundry.org/ro/#OBO_REL:part_of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my brain is part of my body (continuant parthood, two material entities)"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000020"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000017"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000019"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "is part of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this day is part of this year (occurrent parthood)"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://ontologydesignpatterns.org/wiki/Submissions:PartOf"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0040042",
- "val" : "http://purl.obolibrary.org/obo/BFO_0000031"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "part_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "part of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002323",
- "meta" : {
- "definition" : {
- "val" : "A mereological relationship or a topological relationship",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "mereotopologically related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002202",
- "meta" : {
- "definition" : {
- "val" : "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y",
- "xrefs" : [ ]
- },
- "comments" : [ "This is the transitive form of the develops from relation" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Terry Meehan"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Melissa Haendel"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "develops from"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002203",
- "meta" : {
- "definition" : {
- "val" : "inverse of develops from",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000125"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Terry Meehan"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "develops into"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002566",
- "meta" : {
- "definition" : {
- "val" : "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000119",
- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "causally influences (entity-centric)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Vasundra Touré"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "causally influences"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002324",
- "meta" : {
- "definition" : {
- "val" : "A relationship that holds between entities participating in some developmental process (GO:0032502)",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000232",
- "val" : "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "developmentally related to"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002447",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Axiomatization to GO to be added later"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y."
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "phosphorylates"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00018001",
- "meta" : {
- "comments" : [ "Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO." ],
- "xrefs" : [ {
- "val" : "FBdv:00018001"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "substage_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "substage_of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/IAO_0000115",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000122"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "definition"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000051",
- "meta" : {
- "definition" : {
- "val" : "a core relation that holds between a whole and its part",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_gocam", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension" ],
- "xrefs" : [ {
- "val" : "OBO_REL:has_part"
- }, {
- "val" : "BFO:0000051"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "relationship"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "has_part"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "has_part"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000111",
- "val" : "has part"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "this year has part this day (occurrent parthood)"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "my body has part my brain (continuant parthood, two material entities)"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "external"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "has_part"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005270",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10100." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005273",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0043885", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10130." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005274",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0043885", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10160." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005271",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074" ]
- },
- "comments" : [ "Temporal ordering number - 10110." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002563",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://xmlns.com/foaf/0.1/page",
- "val" : "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "interaction relation helper property"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002564",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "molecular interaction relation helper property"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005272",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10120." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S10B"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005277",
- "meta" : {
- "definition" : {
- "val" : "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.",
- "xrefs" : [ "FlyBase:FBrf0021038" ]
- },
- "comments" : [ "Temporal ordering number - 10190." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12C"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005278",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0029744", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10200." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005275",
- "meta" : {
- "definition" : {
- "val" : "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10170." ],
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12A"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005276",
- "meta" : {
- "definition" : {
- "val" : "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10180." ],
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S12B"
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- }, {
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- "val" : "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000589",
- "val" : "causally influenced by (entity-centric)"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "causally influenced by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005268",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).",
- "xrefs" : [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ]
- },
- "comments" : [ "Temporal ordering number - 10080." ],
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- } ]
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- "lbl" : "oogenesis stage S8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005269",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.",
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- },
- "comments" : [ "Temporal ordering number - 10090." ],
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S9"
- }, {
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- "meta" : {
- "definition" : {
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- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "synonyms" : [ {
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- "val" : "in pairwise interaction with",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules."
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- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://purl.obolibrary.org/obo/MI_0914"
- }, {
- "pred" : "http://xmlns.com/foaf/0.1/page",
- "val" : "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
- }, {
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- "val" : "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact."
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Considering relabeling as 'pairwise interacts with'"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "interacts with"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002314",
- "meta" : {
- "definition" : {
- "val" : "q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
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- "val" : "https://github.com/oborel/obo-relations/wiki/ROGuide#defining-property-chains-involving-reflexivity"
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- "val" : "Chris Mungall"
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- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "Because part_of is transitive, inheres in is a sub-relation of inheres in part of"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0001900",
- "val" : "http://purl.obolibrary.org/obo/RO_0001901"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "inheres in part of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002436",
- "meta" : {
- "definition" : {
- "val" : "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
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- "val" : "molecularly binds with"
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- "val" : "binds"
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- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://purl.obolibrary.org/obo/ECO_0000353"
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- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
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- "val" : "Chris Mungall"
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- "type" : "PROPERTY",
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- "meta" : {
- "definition" : {
- "val" : "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.",
- "xrefs" : [ ]
+ ],
+ "equivalentNodesSets": [],
+ "id": "http://purl.obolibrary.org/obo/fbdv.json",
+ "logicalDefinitionAxioms": [
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/FBdv_00007022",
+ "genusIds": [
+ "http://purl.obolibrary.org/obo/GO_0051325"
+ ],
+ "restrictions": [
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+ "propertyId": "http://purl.obolibrary.org/obo/FBdv_00018001"
+ }
+ ]
+ },
+ {
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+ "genusIds": [
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+ ],
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+ {
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+ "propertyId": "http://purl.obolibrary.org/obo/FBdv_00018001"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/GO_0000087",
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+ ],
+ "restrictions": [
+ {
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+ "propertyId": "http://purl.obolibrary.org/obo/RO_0002092"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/GO_0000278",
+ "genusIds": [
+ "http://purl.obolibrary.org/obo/GO_0007049"
+ ],
+ "restrictions": [
+ {
+ "fillerId": "http://purl.obolibrary.org/obo/GO_0140014",
+ "propertyId": "http://purl.obolibrary.org/obo/BFO_0000051"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/GO_0022402",
+ "genusIds": [
+ "http://purl.obolibrary.org/obo/GO_0009987"
+ ],
+ "restrictions": [
+ {
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+ "propertyId": "http://purl.obolibrary.org/obo/BFO_0000050"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/GO_0051329",
+ "genusIds": [
+ "http://purl.obolibrary.org/obo/GO_0051325"
+ ],
+ "restrictions": [
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+ "propertyId": "http://purl.obolibrary.org/obo/RO_0002092"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/GO_0098763",
+ "genusIds": [
+ "http://purl.obolibrary.org/obo/GO_0022403"
+ ],
+ "restrictions": [
+ {
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+ "propertyId": "http://purl.obolibrary.org/obo/RO_0002092"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/GO_0140014",
+ "genusIds": [
+ "http://purl.obolibrary.org/obo/GO_0000280"
+ ],
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+ "propertyId": "http://purl.obolibrary.org/obo/BFO_0000050"
+ }
+ ]
+ },
+ {
+ "definedClassId": "http://purl.obolibrary.org/obo/GO_1903047",
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+ "propertyId": "http://purl.obolibrary.org/obo/BFO_0000050"
+ }
+ ]
}
- },
- "type" : "CLASS",
- "lbl" : "material entity"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym",
- "type" : "PROPERTY",
- "lbl" : "has_narrow_synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007001",
- "meta" : {
- "definition" : {
- "val" : "The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 490. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head an expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage." ],
- "synonyms" : [ {
- "pred" : "hasBroadSynonym",
- "val" : "metamorphosis",
- "xrefs" : [ ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "pupal stage",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "2008-06-05T04:51:40Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "david"
- }, {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "P-stage"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007122",
- "meta" : {
- "definition" : {
- "val" : "47th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1270." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 47 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007000",
- "meta" : {
- "comments" : [ "Temporal ordering number - 20000." ],
- "xrefs" : [ {
- "val" : "GO:0007283"
- } ],
- "basicPropertyValues" : [ {
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- "val" : "david"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2008-06-05T04:51:08Z"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "spermatogenesis"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002430",
- "meta" : {
- "definition" : {
- "val" : "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
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- "val" : "Chris Mungall"
- }, {
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- "val" : "http://purl.obolibrary.org/obo/RO_0002428"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "involved in negative regulation of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007121",
- "meta" : {
- "definition" : {
- "val" : "46th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1260." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 46 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007120",
- "meta" : {
- "definition" : {
- "val" : "45th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1250." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 45 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002431",
- "meta" : {
- "definition" : {
- "val" : "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
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- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "involved in or reguates"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000116",
- "val" : "OWL does not allow defining object properties via a Union"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "involved in or involved in regulation of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002432",
- "meta" : {
- "definition" : {
- "val" : "c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.",
- "xrefs" : [ "GOC:cjm", "GOC:dos" ]
- },
- "comments" : [ "" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "enables activity in",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "executes activity in"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000112",
- "val" : "A protein that enables activity in a cytosol."
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "is active in"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007005",
- "meta" : {
- "definition" : {
- "val" : "The anterior spiracles are fully everted, with 7-9 finger-like projections. The body shortens, withdrawing three apparent abdominal segments and the larva sticks to its substrate.",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- },
- "comments" : [ "Temporal ordering number - 480." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "spiracles everted larva",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "white prepupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "third instar larval stage L2"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007126",
- "meta" : {
- "definition" : {
- "val" : "51st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1310." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 51 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007125",
- "meta" : {
- "definition" : {
- "val" : "50th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1300." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 50 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007004",
- "meta" : {
- "definition" : {
- "val" : "Stage which begins when wandering third instar larva stops crawling. The larva everts its anterior spiracles during this stage.",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- },
- "comments" : [ "Temporal ordering number - 470." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "third instar larval stage L1"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007124",
- "meta" : {
- "definition" : {
- "val" : "49th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1290." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 49 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007003",
- "meta" : {
- "definition" : {
- "val" : "Oogenesis stage that begins when endochorion begins to form at the anterior pole, a process which includes the beginning of formation of the dorsal appendages. During this stage, the follicle cells secrete membranous vesicles that form irregular extracellular plaques. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
- "xrefs" : [ "FlyBase:FBrf0043885" ]
- },
- "comments" : [ "Temporal ordering number - 10150." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "oogenesis stage S11b"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007123",
- "meta" : {
- "definition" : {
- "val" : "48th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1280." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 48 of adulthood"
- }, {
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- "xrefs" : [ "GOC:mtg_cell_cycle" ]
- },
- "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ],
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- "meta" : {
- "comments" : [ "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)" ],
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- "val" : "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 690." ],
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- "definition" : {
- "val" : "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative",
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- } ]
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- "type" : "PROPERTY",
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- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005362",
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- "val" : "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 700." ],
- "synonyms" : [ {
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- "val" : "wing tips grey stage",
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- }, {
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- "id" : "http://purl.obolibrary.org/obo/RO_0002410",
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- "definition" : {
- "val" : "This relation groups causal relations between material entities and causal relations between processes",
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- "val" : "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
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- } ]
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- "type" : "PROPERTY",
- "lbl" : "causally related to"
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- "val" : "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 680." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "thoracic bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11(ii)",
- "xrefs" : [ ]
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- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005365",
- "meta" : {
- "definition" : {
- "val" : "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 730." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P14",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "mature bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P14"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004032",
- "meta" : {
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "cjm"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
- "val" : "http://purl.obolibrary.org/obo/RO_0002264"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2018-01-26T23:49:30Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of or within, positive effect"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0007275",
- "meta" : {
- "definition" : {
- "val" : "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",
- "xrefs" : [ "GOC:dph", "GOC:ems", "GOC:isa_complete", "GOC:tb" ]
- },
- "comments" : [ "Note that this term was 'developmental process'." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_plant" ],
- "basicPropertyValues" : [ {
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- "lbl" : "multicellular organism development"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005366",
- "meta" : {
- "definition" : {
- "val" : "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 740." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P15",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P15"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004031",
- "meta" : {
- "definition" : {
- "val" : "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2018-01-25T23:20:13Z"
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- "val" : "cjm"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "enables subfunction"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004034",
- "meta" : {
- "definition" : {
- "val" : "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive",
- "xrefs" : [ ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004049",
- "val" : "http://purl.obolibrary.org/obo/RO_0002263"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "cjm"
- }, {
- "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso",
- "val" : "http://wiki.geneontology.org/index.php/Acts_upstream_of,_positive_effect"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2018-01-26T23:53:14Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of, positive effect"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005363",
- "meta" : {
- "definition" : {
- "val" : "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 710." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P12(ii)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "wings grey stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P12(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005364",
- "meta" : {
- "definition" : {
- "val" : "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 720." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P13",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "wings black stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P13"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0004033",
- "meta" : {
- "subsets" : [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/RO_0004050",
- "val" : "http://purl.obolibrary.org/obo/RO_0002264"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "cjm"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2018-01-26T23:49:51Z"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "acts upstream of or within, negative effect"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002404",
- "meta" : {
- "definition" : {
- "val" : "inverse of upstream of",
- "xrefs" : [ ]
- },
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "causally downstream of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005358",
- "meta" : {
- "definition" : {
- "val" : "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 660." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005359",
- "meta" : {
- "definition" : {
- "val" : "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 670." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P11(i)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "head bristles stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P11(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002405",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "Chris Mungall"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000114",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000428"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "immediately causally downstream of"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005356",
- "meta" : {
- "definition" : {
- "val" : "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 640." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "amber-eyed stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P9",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P9"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005357",
- "meta" : {
- "definition" : {
- "val" : "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 650." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P10",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "red-eye bald stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P10"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0016301",
- "type" : "CLASS",
- "lbl" : "kinase activity"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_root_00000000",
- "meta" : {
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0100001",
- "val" : "http://purl.obolibrary.org/obo/FBdv_00000000"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000231",
- "val" : "http://purl.obolibrary.org/obo/IAO_0000227"
- } ],
- "deprecated" : true
- },
- "type" : "CLASS"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007092",
- "meta" : {
- "definition" : {
- "val" : "17th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 970." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "lbl" : "day 17 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007091",
- "meta" : {
- "definition" : {
- "val" : "16th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 960." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 16 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007090",
- "meta" : {
- "definition" : {
- "val" : "15th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 950." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
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- "type" : "CLASS",
- "lbl" : "day 15 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007096",
- "meta" : {
- "definition" : {
- "val" : "21st day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1010." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
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- "lbl" : "day 21 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000004",
- "meta" : {
- "definition" : {
- "val" : "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.",
- "xrefs" : [ ]
- }
- },
- "type" : "CLASS",
- "lbl" : "independent continuant"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007095",
- "meta" : {
- "definition" : {
- "val" : "20th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1000." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
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- "type" : "CLASS",
- "lbl" : "day 20 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007094",
- "meta" : {
- "definition" : {
- "val" : "19th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 990." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
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- "type" : "CLASS",
- "lbl" : "day 19 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0006996",
- "meta" : {
- "definition" : {
- "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.",
- "xrefs" : [ "GOC:mah" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_aspergillus" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "single organism organelle organization",
- "xrefs" : [ "GOC:TermGenie" ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "organelle organization and biogenesis",
- "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:mah" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "organelle organisation",
- "xrefs" : [ ]
- }, {
- "pred" : "hasRelatedSynonym",
- "val" : "single-organism organelle organization",
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- "val" : "jl"
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- "val" : "2013-12-19T15:25:51Z"
- } ]
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- "type" : "CLASS",
- "lbl" : "organelle organization"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007093",
- "meta" : {
- "definition" : {
- "val" : "18th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 980." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
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- "type" : "CLASS",
- "lbl" : "day 18 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0007049",
- "meta" : {
- "definition" : {
- "val" : "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.",
- "xrefs" : [ "GOC:go_curators", "GOC:mtg_cell_cycle" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_aspergillus", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl" ],
- "xrefs" : [ {
- "val" : "Wikipedia:Cell_cycle"
- } ],
- "synonyms" : [ {
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- "val" : "cell-division cycle",
- "xrefs" : [ ]
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- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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- "lbl" : "cell cycle"
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- "meta" : {
- "definition" : {
- "val" : "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 580." ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002088",
- "meta" : {
- "comments" : [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "during which starts"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005351",
- "meta" : {
- "definition" : {
- "val" : "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 590." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "Malpighian tubules migrating",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007099",
- "meta" : {
- "definition" : {
- "val" : "24th day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1040." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 24 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007098",
- "meta" : {
- "definition" : {
- "val" : "23rd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1030." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 23 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00007097",
- "meta" : {
- "definition" : {
- "val" : "22nd day after eclosion.",
- "xrefs" : [ "FBC:DOS" ]
- },
- "comments" : [ "Temporal ordering number - 1020." ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "day 22 of adulthood"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002084",
- "meta" : {
- "comments" : [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "during which ends"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005354",
- "meta" : {
- "definition" : {
- "val" : "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 620." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "yellow body stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P7"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002085",
- "meta" : {
- "comments" : [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "di"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "encompasses"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005355",
- "meta" : {
- "definition" : {
- "val" : "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 630." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "yellow-eyed stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P8",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pharate adult stage P8"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005352",
- "meta" : {
- "definition" : {
- "val" : "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 600." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "white Malpighian tubules stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P5(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002086",
- "meta" : {
- "comments" : [ "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)" ],
- "subsets" : [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "ends after"
- }, {
- "id" : "http://purl.obolibrary.org/obo/fbdv#systematic_synonym",
- "meta" : {
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- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasScope",
- "val" : "http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "Systematic synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/RO_0002087",
- "meta" : {
- "comments" : [ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" ],
- "xrefs" : [ {
- "val" : "RO:0002087"
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand",
- "val" : "immediately_preceded_by"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000117",
- "val" : "David Osumi-Sutherland"
- }, {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000118",
- "val" : "starts_at_end_of"
- } ]
- },
- "type" : "PROPERTY",
- "lbl" : "immediately_preceded_by"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005353",
- "meta" : {
- "definition" : {
- "val" : "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 610." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "green Malpighian tubules stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage P6"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005347",
- "meta" : {
- "definition" : {
- "val" : "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 550." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P4(i)",
- "xrefs" : [ ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "buoyant stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P4(i)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005348",
- "meta" : {
- "definition" : {
- "val" : "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 560." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "moving bubble stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P4(ii)",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P4(ii)"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005345",
- "meta" : {
- "definition" : {
- "val" : "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 530." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "bubble prepupa stage",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P3",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P3"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005346",
- "meta" : {
- "definition" : {
- "val" : "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 540." ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "cryptocephalic pupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- }, {
- "pred" : "hasExactSynonym",
- "val" : "pupal stage P4",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "prepupal stage P4"
- }, {
- "id" : "http://purl.obolibrary.org/obo/GO_0140014",
- "meta" : {
- "definition" : {
- "val" : "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",
- "xrefs" : [ "ISBN:0198547684" ]
- },
- "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic" ],
- "synonyms" : [ {
- "pred" : "hasExactSynonym",
- "val" : "mitosis",
- "xrefs" : [ ]
- } ],
- "basicPropertyValues" : [ {
- "pred" : "http://purl.obolibrary.org/obo/IAO_0000233",
- "val" : "https://github.com/geneontology/go-ontology/issues/19910"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
- "val" : "biological_process"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date",
- "val" : "2017-03-23T14:44:23Z"
- }, {
- "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by",
- "val" : "pg"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "mitotic nuclear division"
- }, {
- "id" : "http://purl.obolibrary.org/obo/FBdv_00005349",
- "meta" : {
- "definition" : {
- "val" : "The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).",
- "xrefs" : [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ]
- },
- "comments" : [ "Temporal ordering number - 570. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for Cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head and expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage." ],
- "synonyms" : [ {
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- "val" : "phanerocephalic pupa",
- "xrefs" : [ "FlyBase:FBrf0036849" ]
- } ],
- "basicPropertyValues" : [ {
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- "val" : "FlyBase_development_CV"
- } ]
- },
- "type" : "CLASS",
- "lbl" : "pupal stage"
- }, {
- "id" : "http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym",
- "type" : "PROPERTY",
- "lbl" : "has_broad_synonym"
- }, {
- "id" : "http://purl.obolibrary.org/obo/BFO_0000002",
- "meta" : {
- "definition" : {
- "val" : "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.",
- "xrefs" : [ ]
+ ],
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00000000"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00005259"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00007013"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000700",
+ "val": "http://purl.obolibrary.org/obo/FBdv_00007024"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/creator",
+ "val": "http://orcid.org/0000-0002-1373-1705"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/creator",
+ "val": "http://orcid.org/0000-0002-7073-9172"
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+ },
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+ "val": "https://orcid.org/0000-0002-0027-0858"
+ },
+ {
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+ "val": "An ontology of Drosophila melanogaster developmental stages."
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/title",
+ "val": "FlyBase Developmental Ontology (FBdv)"
+ },
+ {
+ "pred": "http://purl.org/dc/terms/license",
+ "val": "https://creativecommons.org/licenses/by/3.0/"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule",
+ "val": "* FBdv:$sequence(8,7000,10000)$"
+ },
+ {
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+ "val": "10:03:2021 10:38"
+ },
+ {
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+ "val": "FlyBase_development_CV"
+ },
+ {
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+ "val": "1.2"
+ },
+ {
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+ "val": "2021-03-10"
+ }
+ ],
+ "subsets": [],
+ "version": "http://purl.obolibrary.org/obo/fbdv/releases/2021-03-10/fbdv.json",
+ "xrefs": []
+ },
+ "nodes": [
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000002",
+ "lbl": "continuant",
+ "meta": {
+ "definition": {
+ "val": "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000003",
+ "lbl": "occurrent",
+ "meta": {
+ "definition": {
+ "val": "An entity that has temporal parts and that happens, unfolds or develops through time.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000004",
+ "lbl": "independent continuant",
+ "meta": {
+ "definition": {
+ "val": "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000015",
+ "lbl": "process",
+ "meta": {
+ "definition": {
+ "val": "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000020",
+ "lbl": "specifically dependent continuant",
+ "meta": {
+ "definition": {
+ "val": "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000040",
+ "lbl": "material entity",
+ "meta": {
+ "definition": {
+ "val": "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.",
+ "xrefs": []
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000050",
+ "lbl": "part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "is part of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my brain is part of my body (continuant parthood, two material entities)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this day is part of this year (occurrent parthood)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "part_of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000002"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000003"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000004"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000017"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000019"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000020"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0040042",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000031"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "part_of"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Submissions:PartOf"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://www.obofoundry.org/ro/#OBO_REL:part_of"
+ }
+ ],
+ "definition": {
+ "val": "a core relation that holds between a part and its whole",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000050"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000051",
+ "lbl": "has_part",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "has part"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my body has part my brain (continuant parthood, two material entities)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this year has part this day (occurrent parthood)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has_part"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "has_part"
+ }
+ ],
+ "definition": {
+ "val": "a core relation that holds between a whole and its part",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000051"
+ },
+ {
+ "val": "OBO_REL:has_part"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000062",
+ "lbl": "preceded_by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "preceded by"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "is preceded by"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "preceded_by"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/source",
+ "val": "http://www.obofoundry.org/ro/#OBO_REL:preceded_by"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "relationship"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "preceded_by"
+ }
+ ],
+ "definition": {
+ "val": "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "BFO:0000062"
+ },
+ {
+ "val": "OBO_REL:preceded_by"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000063",
+ "lbl": "precedes",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "precedes"
+ }
+ ],
+ "definition": {
+ "val": "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000066",
+ "lbl": "occurs in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "occurs in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "occurs_in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "unfolds in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "unfolds_in"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
+ "val": "http://purl.obolibrary.org/obo/bfo.owl"
+ }
+ ],
+ "comments": [
+ "Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant"
+ ],
+ "definition": {
+ "val": "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/BFO_0000067",
+ "lbl": "contains process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "site of"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#isDefinedBy",
+ "val": "http://purl.obolibrary.org/obo/bfo.owl"
+ }
+ ],
+ "comments": [
+ "Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant"
+ ],
+ "definition": {
+ "val": "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/CARO_0000000",
+ "lbl": "anatomical entity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000412",
+ "val": "http://purl.obolibrary.org/obo/caro.owl"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00000000",
+ "lbl": "Drosophila life",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv_root:00000000"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The life of an individual of the species Drosophila melanogaster, from fertilization to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "Drosophila life cycle",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00000054",
+ "lbl": "cleavage stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 25."
+ ],
+ "definition": {
+ "val": "A collective term for stages 1-4.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00004450",
+ "lbl": "late extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 300."
+ ],
+ "definition": {
+ "val": "A collective term for stages 11 and 12.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00004886",
+ "lbl": "oogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10000."
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "oogenesis stage",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0048477"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005259",
+ "lbl": "developmental stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:56:56Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00007010"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A temporal subdivision of a developmental process.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005261",
+ "lbl": "oogenesis stage S1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10010."
+ ],
+ "definition": {
+ "val": "Earliest stage of ovarian cyst development - lasts while the 16 cell cyst is within the germarium (region 3).",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005262",
+ "lbl": "oogenesis stage S2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10020."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the cyst leaves the germarium (from this point the cyst is referred to as an egg chamber). During this stage, polyploidation of the nurse cells begins, they reach a ploidy of 8C, and follicle cells start to divide.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005263",
+ "lbl": "oogenesis stage S3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10030."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the oocyte chromosomes condense into a karyosome attached to a distinctive spherical structure known as an endobody. The oocyte nucleolus disappears completely. During this stage, nurse cell ploidy reaches 16C.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005264",
+ "lbl": "oogenesis stage S4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10040."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the nurse cells chromosomes become bulbous. Nurse cell chromosomes during this stage are polytene and reach a ploidy of 32C. The egg chamber is oval shaped.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005265",
+ "lbl": "oogenesis stage S5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10050."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell chromosomes are no longer bulbous - the association between homologs weakens so that these chromosomes no longer have a polytene structure. During this stage, posterior nurse cell nuclei have a higher ploidy (64C) than anterior ones.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005266",
+ "lbl": "oogenesis stage S6",
+ "meta": {
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+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10060."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which follicle cell division ceases.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005267",
+ "lbl": "oogenesis stage S7",
+ "meta": {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10070."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which polyploidation and enlargement of follicle cells begins. Nurse cell ploidy ranges from 256C (anterior) to 512C (posterior) and the egg chamber gains an elongated shape.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005268",
+ "lbl": "oogenesis stage S8",
+ "meta": {
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+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10080."
+ ],
+ "definition": {
+ "val": "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005269",
+ "lbl": "oogenesis stage S9",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10090."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005270",
+ "lbl": "oogenesis stage S10",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10100."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005271",
+ "lbl": "oogenesis stage S10A",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10110."
+ ],
+ "definition": {
+ "val": "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005272",
+ "lbl": "oogenesis stage S10B",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10120."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005273",
+ "lbl": "oogenesis stage S11",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10130."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0043885",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005274",
+ "lbl": "oogenesis stage S12",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10160."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0043885",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005275",
+ "lbl": "oogenesis stage S12A",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10170."
+ ],
+ "definition": {
+ "val": "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005276",
+ "lbl": "oogenesis stage S12B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10180."
+ ],
+ "definition": {
+ "val": "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005277",
+ "lbl": "oogenesis stage S12C",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10190."
+ ],
+ "definition": {
+ "val": "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.",
+ "xrefs": [
+ "FlyBase:FBrf0021038"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005278",
+ "lbl": "oogenesis stage S13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10200."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0029744",
+ "FlyBase:FBrf0034074",
+ "FlyBase:FBrf0064777"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005279",
+ "lbl": "oogenesis stage S13A",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005280",
+ "lbl": "oogenesis stage S13B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10220. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which 9-11 nurse cell nuclei remain at the anterior of the oocyte. During this stage, the nuclear membrane of the oocyte nucleus disappears, indicating the start of meiotic pro-metaphase.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005281",
+ "lbl": "oogenesis stage S13C",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10230."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which only 7-8 nurse cell nuclei remain at the anterior of the oocyte. At the beginning of this stage, oocyte chromosome bivalents separate from each other - indicating mid-prometaphase of oocyte meiosis.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005282",
+ "lbl": "oogenesis stage S13D",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10240."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005283",
+ "lbl": "oogenesis stage S14",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10260."
+ ],
+ "definition": {
+ "val": "The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005284",
+ "lbl": "oogenesis stage S14A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10270."
+ ],
+ "definition": {
+ "val": "Secretion and formation of the outer endochorionic network by throughout the follicle. Crystallization of the innermost chorionic layer of the main body follicle cells.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005285",
+ "lbl": "oogenesis stage S14B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10280."
+ ],
+ "definition": {
+ "val": "Secretion of the exochorion begins and ends.",
+ "xrefs": [
+ "FlyBase:FBrf0021038",
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005286",
+ "lbl": "egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10290."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.",
+ "xrefs": [
+ "FlyBase:FBrf0064779"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005287",
+ "lbl": "unfertilized egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10300."
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005288",
+ "lbl": "fertilized egg stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10."
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005289",
+ "lbl": "embryonic stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 20."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from fertilization to hatching.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005290",
+ "lbl": "pre-blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 30."
+ ],
+ "definition": {
+ "val": "Embryonic stage 1-3.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pre-blastoderm",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005291",
+ "lbl": "embryonic stage 1",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 40."
+ ],
+ "definition": {
+ "val": "The embryonic stage that lasts from the end of fertilization to the end of the second nuclear division. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0064779",
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005292",
+ "lbl": "embryonic cycle 1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 50."
+ ],
+ "definition": {
+ "val": "The first mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005293",
+ "lbl": "embryonic stage 2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 70."
+ ],
+ "definition": {
+ "val": "Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005294",
+ "lbl": "embryonic cycle 2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 60."
+ ],
+ "definition": {
+ "val": "The second mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005295",
+ "lbl": "embryonic cycle 3",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 80."
+ ],
+ "definition": {
+ "val": "The third mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005296",
+ "lbl": "embryonic cycle 4",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 90."
+ ],
+ "definition": {
+ "val": "The fourth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005297",
+ "lbl": "embryonic cycle 5",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 100."
+ ],
+ "definition": {
+ "val": "The fifth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005298",
+ "lbl": "embryonic cycle 6",
+ "meta": {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 110."
+ ],
+ "definition": {
+ "val": "The sixth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005299",
+ "lbl": "embryonic cycle 7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 120."
+ ],
+ "definition": {
+ "val": "The seventh mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005300",
+ "lbl": "embryonic cycle 8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 130."
+ ],
+ "definition": {
+ "val": "The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005301",
+ "lbl": "embryonic stage 3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 140."
+ ],
+ "definition": {
+ "val": "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005302",
+ "lbl": "embryonic cycle 9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 150."
+ ],
+ "definition": {
+ "val": "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005303",
+ "lbl": "embryonic cycle 10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 180."
+ ],
+ "definition": {
+ "val": "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005304",
+ "lbl": "blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 160."
+ ],
+ "definition": {
+ "val": "Embryonic stages 4 and 5.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "blastoderm",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005305",
+ "lbl": "syncytial blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005306",
+ "lbl": "embryonic stage 4",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 170."
+ ],
+ "definition": {
+ "val": "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "syncytial blastoderm",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "syncytial blastoderm stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005307",
+ "lbl": "embryonic cycle 11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 185."
+ ],
+ "definition": {
+ "val": "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005308",
+ "lbl": "embryonic cycle 12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 190."
+ ],
+ "definition": {
+ "val": "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005309",
+ "lbl": "embryonic cycle 13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 200."
+ ],
+ "definition": {
+ "val": "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.",
+ "xrefs": [
+ "FlyBase:FBrf0049535"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005310",
+ "lbl": "cellular blastoderm stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005311",
+ "lbl": "embryonic stage 5",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 210."
+ ],
+ "definition": {
+ "val": "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular blastoderm",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular blastoderm stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005312",
+ "lbl": "embryonic cycle 14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "FlyBase:FBrf0049535",
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "first blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005313",
+ "lbl": "embryonic cycle 14A",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 256."
+ ],
+ "definition": {
+ "val": "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "[FlyBase:FBrf0039741"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonic cycle 14 interphase",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005314",
+ "lbl": "embryonic cycle 14B",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.",
+ "xrefs": [
+ "FlyBase:FBrf0039741"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonic cycle 14 M-phase",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005315",
+ "lbl": "embryonic cycle 15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 15th cell cycle of embryogenesis. Asynchronous.",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "second blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005316",
+ "lbl": "embryonic cycle 16",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead."
+ ],
+ "definition": {
+ "val": "The 16th cell cycle division of embryogenesis. Asynchronous.",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "third blastoderm mitosis",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005317",
+ "lbl": "gastrula stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 220."
+ ],
+ "definition": {
+ "val": "Stages during which gastrulation occurs. 6-8.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "gastrula",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005318",
+ "lbl": "embryonic stage 6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 230."
+ ],
+ "definition": {
+ "val": "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005319",
+ "lbl": "embryonic stage 7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 240."
+ ],
+ "definition": {
+ "val": "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005320",
+ "lbl": "germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005321",
+ "lbl": "extended germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 260."
+ ],
+ "definition": {
+ "val": "Stages during which the germ band is extended - 9-12.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005322",
+ "lbl": "embryonic stage 8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 250."
+ ],
+ "definition": {
+ "val": "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "rapidly extending germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005323",
+ "lbl": "embryonic stage 9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 280."
+ ],
+ "definition": {
+ "val": "Stage 9 begins when mesodermal segmentation becomes (transiently) visible\\, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005324",
+ "lbl": "embryonic stage 10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 290."
+ ],
+ "definition": {
+ "val": "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005325",
+ "lbl": "embryonic stage 11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 310."
+ ],
+ "definition": {
+ "val": "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005326",
+ "lbl": "contracted germ band stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005327",
+ "lbl": "embryonic stage 12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 320."
+ ],
+ "definition": {
+ "val": "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "retracting germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005328",
+ "lbl": "embryonic stage 13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 340."
+ ],
+ "definition": {
+ "val": "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "contracted germ band stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005329",
+ "lbl": "head involution stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0100001",
+ "val": "FBdv:00005330"
+ },
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005330",
+ "lbl": "embryonic stage 14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 350."
+ ],
+ "definition": {
+ "val": "Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "head involution stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005331",
+ "lbl": "dorsal closure stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 330."
+ ],
+ "definition": {
+ "val": "A collective term for stages 13-15.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005332",
+ "lbl": "embryonic stage 15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 360."
+ ],
+ "definition": {
+ "val": "Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005333",
+ "lbl": "late embryonic stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 370."
+ ],
+ "definition": {
+ "val": "Embryonic stages 16-17.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005334",
+ "lbl": "embryonic stage 16",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 380."
+ ],
+ "definition": {
+ "val": "Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005335",
+ "lbl": "embryonic stage 17",
+ "meta": {
+ "basicPropertyValues": [
+ {
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 390."
+ ],
+ "definition": {
+ "val": "Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).",
+ "xrefs": [
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005336",
+ "lbl": "larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 400."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005337",
+ "lbl": "first instar larval stage",
+ "meta": {
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+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 410."
+ ],
+ "definition": {
+ "val": "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L1",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "first instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000000"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005338",
+ "lbl": "second instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 420."
+ ],
+ "definition": {
+ "val": "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L2",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "second instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000001"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005339",
+ "lbl": "third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 430."
+ ],
+ "definition": {
+ "val": "The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).",
+ "xrefs": [
+ "FlyBase:FBrf0007733"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "L3",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "third instar larva",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "UBERON:8000002"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005340",
+ "lbl": "early third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T11:51:56Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 440."
+ ],
+ "definition": {
+ "val": "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005341",
+ "lbl": "wandering third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T11:55:46Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 460."
+ ],
+ "definition": {
+ "val": "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "late third instar",
+ "xrefs": []
+ },
+ {
+ "pred": "hasBroadSynonym",
+ "val": "post-feeding larva",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005342",
+ "lbl": "prepupal stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 500."
+ ],
+ "definition": {
+ "val": "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005343",
+ "lbl": "prepupal stage P1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 510."
+ ],
+ "definition": {
+ "val": "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P1",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "puparium formation",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "white puparium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "pupal stage P0",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "white prepupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005344",
+ "lbl": "prepupal stage P2",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 520."
+ ],
+ "definition": {
+ "val": "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "brown puparium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P2",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005345",
+ "lbl": "prepupal stage P3",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 530."
+ ],
+ "definition": {
+ "val": "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "bubble prepupa stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P3",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005346",
+ "lbl": "prepupal stage P4",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 540."
+ ],
+ "definition": {
+ "val": "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cryptocephalic pupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005347",
+ "lbl": "prepupal stage P4(i)",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 550."
+ ],
+ "definition": {
+ "val": "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "buoyant stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005348",
+ "lbl": "prepupal stage P4(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 560."
+ ],
+ "definition": {
+ "val": "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "moving bubble stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P4(ii)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005349",
+ "lbl": "pupal stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 570. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for Cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head and expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage."
+ ],
+ "definition": {
+ "val": "The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "phanerocephalic pupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005350",
+ "lbl": "pupal stage P5",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 580."
+ ],
+ "definition": {
+ "val": "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005351",
+ "lbl": "pupal stage P5(i)",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 590."
+ ],
+ "definition": {
+ "val": "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "Malpighian tubules migrating",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005352",
+ "lbl": "pupal stage P5(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 600."
+ ],
+ "definition": {
+ "val": "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "white Malpighian tubules stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005353",
+ "lbl": "pupal stage P6",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 610."
+ ],
+ "definition": {
+ "val": "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "green Malpighian tubules stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005354",
+ "lbl": "pupal stage P7",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 620."
+ ],
+ "definition": {
+ "val": "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "yellow body stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005355",
+ "lbl": "pharate adult stage P8",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 630."
+ ],
+ "definition": {
+ "val": "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P8",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "yellow-eyed stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005356",
+ "lbl": "pharate adult stage P9",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 640."
+ ],
+ "definition": {
+ "val": "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "amber-eyed stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P9",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005357",
+ "lbl": "pharate adult stage P10",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 650."
+ ],
+ "definition": {
+ "val": "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P10",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "red-eye bald stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005358",
+ "lbl": "pharate adult stage P11",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 660."
+ ],
+ "definition": {
+ "val": "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005359",
+ "lbl": "pharate adult stage P11(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 670."
+ ],
+ "definition": {
+ "val": "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "head bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005360",
+ "lbl": "pharate adult stage P11(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 680."
+ ],
+ "definition": {
+ "val": "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P11(ii)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "thoracic bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005361",
+ "lbl": "pharate adult stage P12",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 690."
+ ],
+ "definition": {
+ "val": "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005362",
+ "lbl": "pharate adult stage P12(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 700."
+ ],
+ "definition": {
+ "val": "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12(i)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wing tips grey stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005363",
+ "lbl": "pharate adult stage P12(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 710."
+ ],
+ "definition": {
+ "val": "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P12(ii)",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wings grey stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005364",
+ "lbl": "pharate adult stage P13",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 720."
+ ],
+ "definition": {
+ "val": "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P13",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "wings black stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005365",
+ "lbl": "pharate adult stage P14",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 730."
+ ],
+ "definition": {
+ "val": "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "mature bristles stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P14",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005366",
+ "lbl": "pharate adult stage P15",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 740."
+ ],
+ "definition": {
+ "val": "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005367",
+ "lbl": "pharate adult stage P15(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 750."
+ ],
+ "definition": {
+ "val": "Tanning of the tergites obscures the Malpighian tubules and the 'yellow body'. Legs begin to twitch; fly is able to walk if puparium is removed prematurely. Ptilinum expands by hydrostatic pressure, opening the operculum. Duration at 25 degrees C: approximately 8 hours, 6 minutes. (211.5-219.6 hours after egg laying; 91.5-99.6 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "meconium stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15(i)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005368",
+ "lbl": "pharate adult stage P15(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 760."
+ ],
+ "definition": {
+ "val": "Stage which starts when the operculum opens and ends when eclosion is completed. Duration at 25 degrees C: approximately 24 minutes. (219.6-220 hours after egg laying; 99.6-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "eclosion stage",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "pupal stage P15(ii)",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005369",
+ "lbl": "adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 770."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from eclosion to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005370",
+ "lbl": "adult stage A1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005373"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 785. The time at which eclosed flies settle down for wing expansion can vary greatly. If they fail to find a suitable site then expansion can be delayed by several hours."
+ ],
+ "definition": {
+ "val": "Newly eclosed adult stage. Animal free of pupal case. Runs rapidly to find site for wing expansion. Wings are folded back and black against a very pale abdomen.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage I",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005371",
+ "lbl": "adult stage A2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005374"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 790."
+ ],
+ "definition": {
+ "val": "Stage, shortly after eclosion, during which the wings expand. During wing expansion, the abdomen pulsates and the hind legs stroke the wings vigorously for several minutes at a time. The stage ends when the wings are folded down over the abdomen, which has become broader and shorter, and the wing cuticle has lost its folds. The stage lasts around 15 minutes at 25'C.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage II",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00005412",
+ "lbl": "gamete",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "This should be considered as a type of cell rather than as a stage. Please use FBbt:00005412."
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00006011",
+ "lbl": "pharate adult stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 625."
+ ],
+ "definition": {
+ "val": "The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).",
+ "xrefs": [
+ "FlyBase:FBrf0036849",
+ "FlyBase:FBrf0048355",
+ "FlyBase:FBrf0049147"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00006012",
+ "lbl": "adult stage A3",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "FBdv:00005375"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 800."
+ ],
+ "definition": {
+ "val": "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.",
+ "xrefs": [
+ "FlyBase:FBrf0049147"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "adult stage III",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007000",
+ "lbl": "spermatogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-06-05T04:51:08Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 20000."
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0007283"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007001",
+ "lbl": "P-stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-06-05T04:51:40Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 490. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head an expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage."
+ ],
+ "definition": {
+ "val": "The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "metamorphosis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "pupal stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007002",
+ "lbl": "oogenesis stage S11a",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10140."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins and ends when the dorsal appendages begin to form.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007003",
+ "lbl": "oogenesis stage S11b",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10150."
+ ],
+ "definition": {
+ "val": "Oogenesis stage that begins when endochorion begins to form at the anterior pole, a process which includes the beginning of formation of the dorsal appendages. During this stage, the follicle cells secrete membranous vesicles that form irregular extracellular plaques. This stage ends when dying nurse cells form an anterior cap to the oocyte.",
+ "xrefs": [
+ "FlyBase:FBrf0043885"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007004",
+ "lbl": "third instar larval stage L1",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 470."
+ ],
+ "definition": {
+ "val": "Stage which begins when wandering third instar larva stops crawling. The larva everts its anterior spiracles during this stage.",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007005",
+ "lbl": "third instar larval stage L2",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 480."
+ ],
+ "definition": {
+ "val": "The anterior spiracles are fully everted, with 7-9 finger-like projections. The body shortens, withdrawing three apparent abdominal segments and the larva sticks to its substrate.",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "spiracles everted larva",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "white prepupa",
+ "xrefs": [
+ "FlyBase:FBrf0036849"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007006",
+ "lbl": "oogenesis stage S13E",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-11-13T06:27:57Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 10250."
+ ],
+ "definition": {
+ "val": "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).",
+ "xrefs": [
+ "FlyBase:FBrf0029744"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007007",
+ "lbl": "late third instar larval stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "david"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2008-12-11T01:19:53Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 450."
+ ],
+ "definition": {
+ "val": "Third instar larva from the beginning of wandering to the beginning of puparium formation.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007008",
+ "lbl": "occurrent",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "deprecated": true
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007009",
+ "lbl": "developmental process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:56:42Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0032502"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007011",
+ "lbl": "embryonic cycle",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:57:41Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.",
+ "xrefs": [
+ "FlyBase:FBrf0049535",
+ "FlyBase:FBrf0089570"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007012",
+ "lbl": "life stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2009-10-01T05:59:22Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "life cycle stage",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007013",
+ "lbl": "age",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-29T12:25:36Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007014",
+ "lbl": "adult age in days",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-29T12:28:05Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Temporal subdivision of adulthood in days post-eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007015",
+ "lbl": "embryonic stage 17(i)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T11:57:15Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007016",
+ "lbl": "embryonic stage 17(ii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:00:15Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 392. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007017",
+ "lbl": "embryonic stage 17(iii)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:01:18Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 393. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007018",
+ "lbl": "embryonic stage 17(iv)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2011-04-26T12:03:14Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 394. Should not be used to stage embryos whose development is at temperatures other than 25'C."
+ ],
+ "definition": {
+ "val": "Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007019",
+ "lbl": "third instar - uncleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994)."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007020",
+ "lbl": "third instar - partially cleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994)."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007021",
+ "lbl": "third instar - cleared gut stage",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994."
+ ],
+ "definition": {
+ "val": "The substage of the wandering third instar larval stage when the larva has cleared its gut contents.",
+ "xrefs": [
+ "FlyBase:FBrf0076598"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007022",
+ "lbl": "embryonic cycle interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The interphase (GO:0051325) of an embryonic cycle.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007023",
+ "lbl": "embryonic cycle M-phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "The M-phase (GO:0000279) of an embryonic cycle.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007024",
+ "lbl": "biological process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "GO:0008150"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007025",
+ "lbl": "immature adult stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-01-08T20:06:59Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 782."
+ ],
+ "definition": {
+ "val": "The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007026",
+ "lbl": "mature adult stage",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "djs93"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-01-10T13:03:54Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "definition": {
+ "val": "Life stage from the end of adult stage A3, when tanning is complete, to death.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007075",
+ "lbl": "day 0 of adulthood",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 780."
+ ],
+ "definition": {
+ "val": "The day of eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007076",
+ "lbl": "day 1 of adulthood",
+ "meta": {
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+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1210."
+ ],
+ "definition": {
+ "val": "41st day after eclosion.",
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+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
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+ "Temporal ordering number - 1220."
+ ],
+ "definition": {
+ "val": "42nd day after eclosion.",
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+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007118",
+ "lbl": "day 43 of adulthood",
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+ "Temporal ordering number - 1230."
+ ],
+ "definition": {
+ "val": "43rd day after eclosion.",
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+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
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+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007119",
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+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1240."
+ ],
+ "definition": {
+ "val": "44th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007120",
+ "lbl": "day 45 of adulthood",
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1250."
+ ],
+ "definition": {
+ "val": "45th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007121",
+ "lbl": "day 46 of adulthood",
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+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1260."
+ ],
+ "definition": {
+ "val": "46th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007122",
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+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1270."
+ ],
+ "definition": {
+ "val": "47th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007123",
+ "lbl": "day 48 of adulthood",
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+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1280."
+ ],
+ "definition": {
+ "val": "48th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007124",
+ "lbl": "day 49 of adulthood",
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+ "val": "FlyBase_development_CV"
+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1290."
+ ],
+ "definition": {
+ "val": "49th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007125",
+ "lbl": "day 50 of adulthood",
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+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1300."
+ ],
+ "definition": {
+ "val": "50th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007126",
+ "lbl": "day 51 of adulthood",
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+ "comments": [
+ "Temporal ordering number - 1310."
+ ],
+ "definition": {
+ "val": "51st day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007127",
+ "lbl": "day 52 of adulthood",
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+ "comments": [
+ "Temporal ordering number - 1320."
+ ],
+ "definition": {
+ "val": "52nd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007128",
+ "lbl": "day 53 of adulthood",
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+ "comments": [
+ "Temporal ordering number - 1330."
+ ],
+ "definition": {
+ "val": "53rd day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007129",
+ "lbl": "day 54 of adulthood",
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+ "comments": [
+ "Temporal ordering number - 1340."
+ ],
+ "definition": {
+ "val": "54th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007130",
+ "lbl": "day 55 of adulthood",
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+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1350."
+ ],
+ "definition": {
+ "val": "55th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007131",
+ "lbl": "day 56 of adulthood",
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+ "comments": [
+ "Temporal ordering number - 1360."
+ ],
+ "definition": {
+ "val": "56th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007132",
+ "lbl": "day 57 of adulthood",
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+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1370."
+ ],
+ "definition": {
+ "val": "57th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007133",
+ "lbl": "day 58 of adulthood",
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+ ],
+ "comments": [
+ "Temporal ordering number - 1380."
+ ],
+ "definition": {
+ "val": "58th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007134",
+ "lbl": "day 59 of adulthood",
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+ ],
+ "comments": [
+ "Temporal ordering number - 1390."
+ ],
+ "definition": {
+ "val": "59th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00007135",
+ "lbl": "day 60 of adulthood",
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
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+ }
+ ],
+ "comments": [
+ "Temporal ordering number - 1400."
+ ],
+ "definition": {
+ "val": "60th day after eclosion.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00014201",
+ "lbl": "early extended germ band stage",
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+ "val": "FlyBase_development_CV"
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+ ],
+ "comments": [
+ "Temporal ordering number - 270."
+ ],
+ "definition": {
+ "val": "A collective term for stages 9 and 10.",
+ "xrefs": [
+ "FBC:DOS"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/FBdv_00018001",
+ "lbl": "substage_of",
+ "meta": {
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+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "substage_of"
+ }
+ ],
+ "comments": [
+ "Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO."
+ ],
+ "xrefs": [
+ {
+ "val": "FBdv:00018001"
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+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000087",
+ "lbl": "mitotic M phase",
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+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
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+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
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+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "M phase of mitotic cell cycle",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "M-phase of mitotic cell cycle",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000278",
+ "lbl": "mitotic cell cycle",
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle."
+ ],
+ "definition": {
+ "val": "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.",
+ "xrefs": [
+ "GOC:mah",
+ "ISBN:0815316194",
+ "Reactome:69278"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_drosophila",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_yeast"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "mitosis",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Mitosis"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0000279",
+ "lbl": "M phase",
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+ "val": "biological_process"
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+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
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+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "M-phase",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:M_phase"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
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+ "lbl": "nuclear division",
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+ }
+ ],
+ "definition": {
+ "val": "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "karyokinesis",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0003674",
+ "lbl": "molecular_function",
+ "meta": {
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+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "molecular process"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0006996",
+ "lbl": "organelle organization",
+ "meta": {
+ "basicPropertyValues": [
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+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2013-12-19T15:25:51Z"
+ },
+ {
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+ "val": "GO:1902589"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.",
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+ "GOC:mah"
+ ]
+ },
+ "subsets": [
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+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "organelle organisation",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "single organism organelle organization",
+ "xrefs": [
+ "GOC:TermGenie"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "organelle organization and biogenesis",
+ "xrefs": [
+ "GOC:dph",
+ "GOC:jl",
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism organelle organization",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0007049",
+ "lbl": "cell cycle",
+ "meta": {
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.",
+ "xrefs": [
+ "GOC:go_curators",
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
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+ "http://purl.obolibrary.org/obo/go#goslim_agr",
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_candida",
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
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+ "val": "cell-division cycle",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
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+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0007275",
+ "lbl": "multicellular organism development",
+ "meta": {
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+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term was 'developmental process'."
+ ],
+ "definition": {
+ "val": "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",
+ "xrefs": [
+ "GOC:dph",
+ "GOC:ems",
+ "GOC:isa_complete",
+ "GOC:tb"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0008150",
+ "lbl": "biological_process",
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+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-09-19T15:05:24Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0000004"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0007582"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044699"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this."
+ ],
+ "definition": {
+ "val": "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.",
+ "xrefs": [
+ "GOC:pdt"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_candida",
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_metagenomics",
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_plant",
+ "http://purl.obolibrary.org/obo/go#goslim_pombe",
+ "http://purl.obolibrary.org/obo/go#goslim_yeast"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "biological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "physiological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single organism process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism process",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Biological_process"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0009790",
+ "lbl": "embryo development",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0009795"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.",
+ "xrefs": [
+ "GOC:go_curators",
+ "GOC:isa_complete",
+ "GOC:mtg_sensu"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate",
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "embryogenesis and morphogenesis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryogenesis",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "embryonal development",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Embryogenesis"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0009987",
+ "lbl": "cellular process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-12-11T16:56:55Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0008151"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044763"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0050875"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.",
+ "xrefs": [
+ "GOC:go_curators",
+ "GOC:isa_complete"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cell physiology",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular physiological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "cell growth and/or maintenance",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism cellular process",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0016043",
+ "lbl": "cellular component organization",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044235"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0071842"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.",
+ "xrefs": [
+ "GOC:ai",
+ "GOC:jl",
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_agr",
+ "http://purl.obolibrary.org/obo/go#goslim_mouse",
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cell organisation",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation at cellular level",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation in other organism",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organization at cellular level",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organization in other organism",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "cell organization and biogenesis",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0022402",
+ "lbl": "cell cycle process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.",
+ "xrefs": [
+ "GOC:isa_complete",
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0022403",
+ "lbl": "cell cycle phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0032501",
+ "lbl": "multicellular organismal process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002161",
+ "val": "http://purl.obolibrary.org/obo/NCBITaxon_4896"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002161",
+ "val": "http://purl.obolibrary.org/obo/NCBITaxon_4932"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-09-19T16:07:47Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044707"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0050874"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "Any biological process, occurring at the level of a multicellular organism, pertinent to its function.",
+ "xrefs": [
+ "GOC:curators",
+ "GOC:dph",
+ "GOC:isa_complete",
+ "GOC:tb"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "organismal physiological process",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-multicellular organism process",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0032502",
+ "lbl": "developmental process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2012-12-19T12:21:31Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0044767"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.",
+ "xrefs": [
+ "GOC:isa_complete"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_agr",
+ "http://purl.obolibrary.org/obo/go#goslim_aspergillus",
+ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon",
+ "http://purl.obolibrary.org/obo/go#goslim_pir"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasNarrowSynonym",
+ "val": "development",
+ "xrefs": []
+ },
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "single-organism developmental process",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0044848",
+ "lbl": "biological phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2014-07-16T13:12:40Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase."
+ ],
+ "definition": {
+ "val": "A distinct period or stage in a biological process or cycle.",
+ "xrefs": [
+ "GOC:jl"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0045448",
+ "lbl": "mitotic cell cycle, embryonic",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.",
+ "xrefs": [
+ "GOC:go_curators"
+ ]
+ }
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0048285",
+ "lbl": "organelle fission",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The creation of two or more organelles by division of one organelle.",
+ "xrefs": [
+ "GOC:jid"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_pir",
+ "http://purl.obolibrary.org/obo/go#goslim_yeast"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0048856",
+ "lbl": "anatomical structure development",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.",
+ "xrefs": [
+ "GO_REF:0000021"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic",
+ "http://purl.obolibrary.org/obo/go#goslim_plant"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "development of an anatomical structure",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0051325",
+ "lbl": "interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasBroadSynonym",
+ "val": "resting phase",
+ "xrefs": []
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "karyostasis",
+ "xrefs": []
+ }
+ ],
+ "xrefs": [
+ {
+ "val": "Wikipedia:Interphase"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0051329",
+ "lbl": "mitotic interphase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.",
+ "xrefs": [
+ "GOC:mtg_cell_cycle"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "interphase of mitotic cell cycle",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0071840",
+ "lbl": "cellular component organization or biogenesis",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "mah"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2010-09-10T01:39:16Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId",
+ "val": "GO:0071841"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon",
+ "http://purl.obolibrary.org/obo/go#goslim_metagenomics"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation or biogenesis",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organisation or biogenesis at cellular level",
+ "xrefs": [
+ "GOC:mah"
+ ]
+ },
+ {
+ "pred": "hasExactSynonym",
+ "val": "cellular component organization or biogenesis at cellular level",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0098763",
+ "lbl": "mitotic cell cycle phase",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "comments": [
+ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)."
+ ],
+ "definition": {
+ "val": "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_0140014",
+ "lbl": "mitotic nuclear division",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000233",
+ "val": "https://github.com/geneontology/go-ontology/issues/19910"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "pg"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-03-23T14:44:23Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",
+ "xrefs": [
+ "ISBN:0198547684"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#goslim_chembl",
+ "http://purl.obolibrary.org/obo/go#goslim_generic"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "mitosis",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/GO_1903047",
+ "lbl": "mitotic cell cycle process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "jl"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2014-05-22T14:22:34Z"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "biological_process"
+ }
+ ],
+ "definition": {
+ "val": "A process that is part of the mitotic cell cycle.",
+ "xrefs": [
+ "GOC:TermGenie",
+ "GOC:mtg_cell_cycle",
+ "GO_REF:0000060"
+ ]
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate"
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/IAO_0000115",
+ "lbl": "definition",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000122"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/PATO_0000001",
+ "lbl": "quality",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "quality (PATO)"
+ }
+ ]
+ },
+ "type": "CLASS"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0000056",
+ "lbl": "participates in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "participates in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this blood clot participates in this blood coagulation"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this input material (or this output material) participates in this process"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this investigator participates in this investigation"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "participates_in"
+ }
+ ],
+ "definition": {
+ "val": "a relation between a continuant and a process, in which the continuant is somehow involved in the process",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0000057",
+ "lbl": "has participant",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000111",
+ "val": "has participant"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this blood coagulation has participant this blood clot"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this investigation has participant this investigator"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "this process has participant this input material (or this output material)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has_participant"
+ },
+ {
+ "pred": "http://purl.org/dc/elements/1.1/source",
+ "val": "http://www.obofoundry.org/ro/#OBO_REL:has_participant"
+ }
+ ],
+ "definition": {
+ "val": "a relation between a process and a continuant, in which the continuant is somehow involved in the process",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002012",
+ "lbl": "occurent part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "occurent_part_of"
+ }
+ ],
+ "definition": {
+ "val": "A part of relation that applies only between occurents.",
+ "xrefs": []
+ },
+ "xrefs": [
+ {
+ "val": "RO:0002012"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002013",
+ "lbl": "has regulatory component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:30:46Z"
+ }
+ ],
+ "definition": {
+ "val": "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002014",
+ "lbl": "has negative regulatory component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:31:01Z"
+ }
+ ],
+ "comments": [
+ "By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'."
+ ],
+ "definition": {
+ "val": "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002015",
+ "lbl": "has positive regulatory component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:31:17Z"
+ }
+ ],
+ "comments": [
+ "By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'."
+ ],
+ "definition": {
+ "val": "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002017",
+ "lbl": "has component activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:44:33Z"
+ }
+ ],
+ "comments": [
+ "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B."
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002018",
+ "lbl": "has component process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-05-24T09:49:21Z"
+ }
+ ],
+ "definition": {
+ "val": "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002022",
+ "lbl": "directly regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-17T13:52:24Z"
+ }
+ ],
+ "comments": [
+ "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2."
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002023",
+ "lbl": "directly negatively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-17T13:52:38Z"
+ }
+ ],
+ "definition": {
+ "val": "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002024",
+ "lbl": "directly positively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-17T13:52:47Z"
+ }
+ ],
+ "definition": {
+ "val": "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002025",
+ "lbl": "has effector activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "dos"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2017-09-22T14:14:36Z"
+ }
+ ],
+ "comments": [
+ "This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations."
+ ],
+ "definition": {
+ "val": "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.",
+ "xrefs": [
+ "GOC:dos"
+ ]
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002084",
+ "lbl": "during which ends",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ }
+ ],
+ "comments": [
+ "Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range."
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002085",
+ "lbl": "encompasses",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "di"
+ }
+ ],
+ "comments": [
+ "Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range."
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002086",
+ "lbl": "ends after",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ }
+ ],
+ "comments": [
+ "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002087",
+ "lbl": "immediately_preceded_by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "starts_at_end_of"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "immediately_preceded_by"
+ }
+ ],
+ "comments": [
+ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002087"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002088",
+ "lbl": "during which starts",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ }
+ ],
+ "comments": [
+ "Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range."
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002090",
+ "lbl": "ends_at_start_of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "ends_at_start_of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "meets"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002575",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000063"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "ends_at_start_of"
+ }
+ ],
+ "comments": [
+ "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002090"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002091",
+ "lbl": "starts during",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "io"
+ }
+ ],
+ "comments": [
+ "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002092",
+ "lbl": "happens during",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "d"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "during"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "happens_during"
+ }
+ ],
+ "comments": [
+ "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002092"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002093",
+ "lbl": "ends during",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "o"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "overlaps"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "external"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "ends_during"
+ }
+ ],
+ "comments": [
+ "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). "
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002093"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002131",
+ "lbl": "overlaps",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000424",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace",
+ "val": "FlyBase_development_CV"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand",
+ "val": "overlaps"
+ }
+ ],
+ "definition": {
+ "val": "x overlaps y if and only if there exists some z such that x has part z and z part of y",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ],
+ "xrefs": [
+ {
+ "val": "RO:0002131"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002180",
+ "lbl": "has component",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Submissions:Componency"
+ }
+ ],
+ "definition": {
+ "val": "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002202",
+ "lbl": "develops from",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Melissa Haendel"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Terry Meehan"
+ }
+ ],
+ "comments": [
+ "This is the transitive form of the develops from relation"
+ ],
+ "definition": {
+ "val": "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002203",
+ "lbl": "develops into",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Osumi-Sutherland"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Terry Meehan"
+ }
+ ],
+ "definition": {
+ "val": "inverse of develops from",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002211",
+ "lbl": "regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "David Hill"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Tanya Berardini"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "GO"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Regulation precludes parthood; the regulatory process may not be within the regulated process."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "regulates (processual)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000600",
+ "val": "false"
+ }
+ ],
+ "definition": {
+ "val": "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002212",
+ "lbl": "negatively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "negatively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002211"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002213",
+ "lbl": "positively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "positively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002211"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002215",
+ "lbl": "capable of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "osteoclast SubClassOf 'capable of' some 'bone resorption'"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has function realized in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/20123131"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/21208450"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"."
+ }
+ ],
+ "definition": {
+ "val": "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. ",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002216",
+ "lbl": "capable of part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has function in"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "https://github.com/oborel/obo-relations/wiki/ROGuide#defining-property-chains-involving-reflexivity"
+ }
+ ],
+ "definition": {
+ "val": "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002222",
+ "lbl": "temporally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "https://en.wikipedia.org/wiki/Allen%27s_interval_algebra"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends."
+ },
+ {
+ "pred": "http://purl.org/dc/terms/source",
+ "val": "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1"
+ }
+ ],
+ "comments": [
+ "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations."
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002233",
+ "lbl": "has input",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "consumes"
+ }
+ ],
+ "definition": {
+ "val": "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco",
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002254",
+ "lbl": "has developmental contribution from",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has developmental contribution from y iff x has some part z such that z develops from y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002255",
+ "lbl": "developmentally contributes to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of has developmental contribution from",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002258",
+ "lbl": "developmentally preceded by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "false"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "In general you should not use this relation to make assertions - use one of the more specific relations below this one"
+ }
+ ],
+ "comments": [
+ "This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from"
+ ],
+ "definition": {
+ "val": "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002263",
+ "lbl": "acts upstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision."
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of"
+ }
+ ],
+ "definition": {
+ "val": "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002264",
+ "lbl": "acts upstream of or within",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway."
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within"
+ }
+ ],
+ "definition": {
+ "val": "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "affects",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002286",
+ "lbl": "developmentally succeeded by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000125"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "Inverse of developmentally preceded by",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002304",
+ "lbl": "causally upstream of, positive effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002411"
+ },
+ {
+ "pred": "http://purl.org/dc/terms/creator",
+ "val": "cjm"
+ }
+ ],
+ "comments": [
+ "holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y"
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002305",
+ "lbl": "causally upstream of, negative effect",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002411"
+ },
+ {
+ "pred": "http://purl.org/dc/terms/creator",
+ "val": "cjm"
+ }
+ ],
+ "comments": [
+ "holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002314",
+ "lbl": "inheres in part of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Because part_of is transitive, inheres in is a sub-relation of inheres in part of"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "https://github.com/oborel/obo-relations/wiki/ROGuide#defining-property-chains-involving-reflexivity"
+ }
+ ],
+ "definition": {
+ "val": "q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002323",
+ "lbl": "mereotopologically related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0001900",
+ "val": "http://purl.obolibrary.org/obo/RO_0001901"
+ }
+ ],
+ "definition": {
+ "val": "A mereological relationship or a topological relationship",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002324",
+ "lbl": "developmentally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development"
+ }
+ ],
+ "definition": {
+ "val": "A relationship that holds between entities participating in some developmental process (GO:0032502)",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002327",
+ "lbl": "enables",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "a particular instances of akt-2 enables some instance of protein kinase activity"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "catalyzes"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "executes"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "has"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "is catalyzing"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "is executing"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time."
+ }
+ ],
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_gp2term"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002328",
+ "lbl": "functionally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This is a grouping relation that collects relations used for the purpose of connecting structure and function"
+ }
+ ],
+ "definition": {
+ "val": "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002329",
+ "lbl": "part of structure that is capable of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "false"
+ }
+ ],
+ "definition": {
+ "val": "this relation holds between c and p when c is part of some c', and c' is capable of p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002331",
+ "lbl": "involved in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "actively involved in"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "enables part of"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://wiki.geneontology.org/index.php/Involved_in"
+ }
+ ],
+ "definition": {
+ "val": "c involved_in p if and only if c enables some process p', and p' is part of p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002333",
+ "lbl": "enabled by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of enables",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002334",
+ "lbl": "regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "regulated by (processual)"
+ }
+ ],
+ "definition": {
+ "val": "inverse of regulates",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002335",
+ "lbl": "negatively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of negatively regulates",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002336",
+ "lbl": "positively regulated by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of positively regulates",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002352",
+ "lbl": "input of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of has input",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259",
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002384",
+ "lbl": "has developmental potential involving",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002385",
+ "lbl": "has potential to developmentally contribute to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002387",
+ "lbl": "has potential to develop into",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has the potential to develop into y iff x develops into y or if x is capable of developing into y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002388",
+ "lbl": "has potential to directly develop into",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002404",
+ "lbl": "causally downstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "inverse of upstream of",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002405",
+ "lbl": "immediately causally downstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002410",
+ "lbl": "causally related to",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ }
+ ],
+ "definition": {
+ "val": "This relation groups causal relations between material entities and causal relations between processes",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002411",
+ "lbl": "causally upstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002412",
+ "lbl": "immediately causally upstream of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000114",
+ "val": "http://purl.obolibrary.org/obo/IAO_0000428"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002575",
+ "val": "http://purl.obolibrary.org/obo/RO_0002411"
+ }
+ ],
+ "definition": {
+ "val": "p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002418",
+ "lbl": "causally upstream of or within",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "influences (processual)"
+ }
+ ],
+ "definition": {
+ "val": "p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasRelatedSynonym",
+ "val": "affects",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002427",
+ "lbl": "causally downstream of or within",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "inverse of causally upstream of or within",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/RO_0002259"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002428",
+ "lbl": "involved in regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "c involved in regulation of p if c is involved in some p' and p' regulates some p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002429",
+ "lbl": "involved in positive regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002428"
+ }
+ ],
+ "definition": {
+ "val": "c involved in regulation of p if c is involved in some p' and p' positively regulates some p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002430",
+ "lbl": "involved in negative regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002428"
+ }
+ ],
+ "definition": {
+ "val": "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002431",
+ "lbl": "involved in or involved in regulation of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "OWL does not allow defining object properties via a Union"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "involved in or reguates"
+ }
+ ],
+ "definition": {
+ "val": "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002432",
+ "lbl": "is active in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "A protein that enables activity in a cytosol."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "executes activity in"
+ }
+ ],
+ "comments": [
+ ""
+ ],
+ "definition": {
+ "val": "c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.",
+ "xrefs": [
+ "GOC:cjm",
+ "GOC:dos"
+ ]
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "enables activity in",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002434",
+ "lbl": "interacts with",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Considering relabeling as 'pairwise interacts with'"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules."
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/MI_0914"
+ },
+ {
+ "pred": "http://xmlns.com/foaf/0.1/page",
+ "val": "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
+ }
+ ],
+ "definition": {
+ "val": "A relationship that holds between two entities in which the processes executed by the two entities are causally connected.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ],
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "in pairwise interaction with",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002436",
+ "lbl": "molecularly interacts with",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "binds"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "molecularly binds with"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/ECO_0000353"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/MI_0915"
+ }
+ ],
+ "definition": {
+ "val": "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002447",
+ "lbl": "phosphorylates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Axiomatization to GO to be added later"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y."
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002448",
+ "lbl": "directly regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ }
+ ],
+ "definition": {
+ "val": "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "molecularly controls",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002449",
+ "lbl": "directly negatively regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "directly inhibits"
+ }
+ ],
+ "definition": {
+ "val": "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "molecularly decreases activity of",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002450",
+ "lbl": "directly positively regulates activity of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000118",
+ "val": "directly activates"
+ }
+ ],
+ "definition": {
+ "val": "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.",
+ "xrefs": []
+ },
+ "synonyms": [
+ {
+ "pred": "hasExactSynonym",
+ "val": "molecularly increases activity of",
+ "xrefs": []
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002464",
+ "lbl": "helper property (not for use in curation)",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning."
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002479",
+ "lbl": "has part that occurs in",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002481",
+ "lbl": "is kinase activity",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002500",
+ "lbl": "causal agent in process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "A relationship between a material entity and a process where the material entity has some causal role that influences the process",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002501",
+ "lbl": "causal relation between processes",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ }
+ ],
+ "definition": {
+ "val": "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002502",
+ "lbl": "depends on",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://purl.obolibrary.org/obo/BFO_0000169"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002506",
+ "lbl": "causal relation between entities",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002559",
+ "lbl": "causally influenced by",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "causally influenced by (entity-centric)"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002563",
+ "lbl": "interaction relation helper property",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso",
+ "val": "http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29"
+ },
+ {
+ "pred": "http://xmlns.com/foaf/0.1/page",
+ "val": "https://github.com/oborel/obo-relations/wiki/InteractionRelations"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002564",
+ "lbl": "molecular interaction relation helper property",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002566",
+ "lbl": "causally influences",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Vasundra Touré"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "causally influences (entity-centric)"
+ }
+ ],
+ "definition": {
+ "val": "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002573",
+ "lbl": "has modifier",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://www.ncbi.nlm.nih.gov/pubmed/20064205"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000232",
+ "val": "This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the \"modifiers\" are."
+ }
+ ],
+ "definition": {
+ "val": "A relation that holds between an attribute or a qualifier and another attribute.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002578",
+ "lbl": "directly regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "directly regulates (processual)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0002575",
+ "val": "http://purl.obolibrary.org/obo/RO_0002211"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002581",
+ "lbl": "is a defining property chain axiom",
+ "meta": {
+ "definition": {
+ "val": "If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002582",
+ "lbl": "is a defining property chain axiom where second argument is reflexive",
+ "meta": {
+ "definition": {
+ "val": "If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002584",
+ "lbl": "has part structure that is capable of",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ }
+ ],
+ "definition": {
+ "val": "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002595",
+ "lbl": "causal relation between material entity and a process",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000116",
+ "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect."
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000117",
+ "val": "Chris Mungall"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002596",
+ "lbl": "capable of regulating",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "pyrethroid -> growth"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Holds between c and p if and only if c is capable of some activity a, and a regulates p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002597",
+ "lbl": "capable of negatively regulating",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002598",
+ "lbl": "capable of positively regulating",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000112",
+ "val": "renin -> arteriolar smooth muscle contraction"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002608",
+ "lbl": "process has causal agent",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ }
+ ],
+ "definition": {
+ "val": "Inverse of 'causal agent in process'",
+ "xrefs": []
+ }
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002629",
+ "lbl": "directly positively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "directly positively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004049",
+ "val": "http://purl.obolibrary.org/obo/RO_0002578"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0002630",
+ "lbl": "directly negatively regulates",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000119",
+ "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/IAO_0000589",
+ "val": "directly negatively regulates (process to process)"
+ },
+ {
+ "pred": "http://purl.obolibrary.org/obo/RO_0004050",
+ "val": "http://purl.obolibrary.org/obo/RO_0002578"
+ }
+ ],
+ "definition": {
+ "val": "Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2.",
+ "xrefs": []
+ },
+ "subsets": [
+ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension",
+ "http://purl.obolibrary.org/obo/valid_for_go_ontology",
+ "http://purl.obolibrary.org/obo/valid_for_gocam"
+ ]
+ },
+ "type": "PROPERTY"
+ },
+ {
+ "id": "http://purl.obolibrary.org/obo/RO_0004031",
+ "lbl": "enables subfunction",
+ "meta": {
+ "basicPropertyValues": [
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#created_by",
+ "val": "cjm"
+ },
+ {
+ "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date",
+ "val": "2018-01-25T23:20:13Z"
+ }
+ ],
+ "definition": {
+ "val": "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.",
+ "xrefs": []
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- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000066", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002430",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002331", "http://purl.obolibrary.org/obo/RO_0002212" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000063",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002092", "http://purl.obolibrary.org/obo/BFO_0000063" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002429",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002331", "http://purl.obolibrary.org/obo/RO_0002213" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002566",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002411", "http://purl.obolibrary.org/obo/RO_0002233" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002213",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002212", "http://purl.obolibrary.org/obo/RO_0002212" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002430",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002212" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002255",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002203", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002428",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002211" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002331",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002331", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002092", "http://purl.obolibrary.org/obo/BFO_0000062" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002131",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000050", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002479",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000051", "http://purl.obolibrary.org/obo/BFO_0000066" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002331",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002327",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/BFO_0000051" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002254",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000051", "http://purl.obolibrary.org/obo/RO_0002202" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002449",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002630", "http://purl.obolibrary.org/obo/RO_0002333" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002432",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/BFO_0000066" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000050", "http://purl.obolibrary.org/obo/BFO_0000062" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002429",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002213" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002211",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002578", "http://purl.obolibrary.org/obo/RO_0002578" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002314",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002314", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000063",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000050", "http://purl.obolibrary.org/obo/BFO_0000063" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002329",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000050", "http://purl.obolibrary.org/obo/RO_0002215" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0004035",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002305" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002448",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002211", "http://purl.obolibrary.org/obo/RO_0002333" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0004032",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0004047" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002584",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000051", "http://purl.obolibrary.org/obo/RO_0002215" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002263",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002411" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0000057",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000051", "http://purl.obolibrary.org/obo/RO_0000057" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002131",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000051", "http://purl.obolibrary.org/obo/RO_0002131" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002131",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002131", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0004034",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002304" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002264",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002418" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0004033",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0004046" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002596",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/RO_0002211" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002450",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002629", "http://purl.obolibrary.org/obo/RO_0002333" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002327",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002017" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002086",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002093", "http://purl.obolibrary.org/obo/BFO_0000062" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002597",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/RO_0002212" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000062",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002091", "http://purl.obolibrary.org/obo/BFO_0000062" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002216",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002566",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/RO_0002411", "http://purl.obolibrary.org/obo/RO_0002333" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002428",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002331", "http://purl.obolibrary.org/obo/RO_0002211" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/BFO_0000066",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000050", "http://purl.obolibrary.org/obo/BFO_0000066" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002598",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002215", "http://purl.obolibrary.org/obo/RO_0002213" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0004031",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002327", "http://purl.obolibrary.org/obo/BFO_0000051" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002131",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/BFO_0000051", "http://purl.obolibrary.org/obo/BFO_0000050" ]
- }, {
- "predicateId" : "http://purl.obolibrary.org/obo/RO_0002211",
- "chainPredicateIds" : [ "http://purl.obolibrary.org/obo/RO_0002211", "http://purl.obolibrary.org/obo/RO_0002025" ]
- } ]
- } ]
-}
\ No newline at end of file
+ ]
+ }
+ ]
+}
diff --git a/fbdv.obo b/fbdv.obo
index 207ac0d..2bf2d47 100644
--- a/fbdv.obo
+++ b/fbdv.obo
@@ -1,6 +1,6 @@
format-version: 1.2
-data-version: fbdv/releases/2021-01-13
-date: 13:01:2021 12:25
+data-version: fbdv/releases/2021-03-10
+date: 10:03:2021 10:38
subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation"
subsetdef: gocheck_do_not_manually_annotate "Term not to be used for direct manual annotation"
subsetdef: goslim_aspergillus "Aspergillus GO slim"
@@ -33,7 +33,7 @@ property_value: IAO:0000700 FBdv:00000000
property_value: IAO:0000700 FBdv:00005259
property_value: IAO:0000700 FBdv:00007013
property_value: IAO:0000700 FBdv:00007024
-property_value: owl:versionInfo "2021-01-13" xsd:string
+property_value: owl:versionInfo "2021-03-10" xsd:string
[Term]
id: FBdv:00000000
@@ -327,6 +327,7 @@ comment: Temporal ordering number - 10.
is_a: FBdv:00005259 ! developmental stage
relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
relationship: substage_of FBdv:00005286 ! egg stage
+relationship: substage_of FBdv:00005289 ! embryonic stage
[Term]
id: FBdv:00005289
@@ -334,7 +335,7 @@ name: embryonic stage
def: "The stage of the Drosophila life-cycle from fertilization to hatching." [FBC:DOS]
comment: Temporal ordering number - 20.
is_a: FBdv:00007012 ! life stage
-relationship: immediately_preceded_by FBdv:00005288 ! fertilized egg stage
+relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
[Term]
id: FBdv:00005290
@@ -780,6 +781,7 @@ def: "The first larval instar begins at hatching and ends at the first larval mo
comment: Temporal ordering number - 410.
synonym: "first instar larva" EXACT []
synonym: "L1" EXACT []
+xref: UBERON:8000000
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005289 ! embryonic stage
relationship: immediately_preceded_by FBdv:00005333 ! late embryonic stage
@@ -794,6 +796,7 @@ def: "The second larval instar begins at the first larval molt and ends at the s
comment: Temporal ordering number - 420.
synonym: "L2" EXACT []
synonym: "second instar larva" EXACT []
+xref: UBERON:8000001
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005337 ! first instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -805,6 +808,7 @@ def: "The third larval instar begins at the second larval molt and ends at pupar
comment: Temporal ordering number - 430.
synonym: "L3" EXACT []
synonym: "third instar larva" RELATED []
+xref: UBERON:8000002
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005338 ! second instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -2003,6 +2007,7 @@ relationship: substage_of FBdv:00005321 ! extended germ band stage
id: ends_at_start_of
name: immediately precedes
comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)
+subset: ro-eco
xref: RO:0002090
property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string
property_value: IAO:0000118 "ends_at_start_of" xsd:string
@@ -2016,6 +2021,7 @@ comment: X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X))
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
+subset: ro-eco
xref: RO:0002092
property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string
property_value: IAO:0000118 "d" xsd:string
@@ -2067,6 +2073,7 @@ name: overlaps
def: "x overlaps y if and only if there exists some z such that x has part z and z part of y" []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_gocam
+subset: ro-eco
xref: RO:0002131
property_value: IAO:0000114 IAO:0000125
property_value: RO:0001900 RO:0001901
@@ -2078,6 +2085,7 @@ id: preceded_by
name: preceded_by
namespace: relationship
def: "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." []
+subset: ro-eco
xref: BFO:0000062
xref: OBO_REL:preceded_by
property_value: http://purl.org/dc/elements/1.1/source http://www.obofoundry.org/ro/#OBO_REL:preceded_by xsd:string
@@ -2096,5 +2104,5 @@ comment: Creating this relation as a temporary fix, pending adding the axiom occ
xref: FBdv:00018001
is_transitive: true
is_a: happens_during ! happens during
-is_a: occurent_part_of ! occurent part of
+is_a: occurent_part_of ! occurent_part_of
diff --git a/fbdv.owl b/fbdv.owl
index 99fa113..a135042 100644
--- a/fbdv.owl
+++ b/fbdv.owl
@@ -18,7 +18,7 @@
xmlns:subsets="http://purl.obolibrary.org/obo/ro/subsets#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
-
+
@@ -31,10 +31,10 @@
FlyBase Developmental Ontology (FBdv)
https://creativecommons.org/licenses/by/3.0/
* FBdv:$sequence(8,7000,10000)$
- 13:01:2021 12:24
+ 10:03:2021 10:38
FlyBase_development_CV
1.2
- 2021-01-13
+ 2021-03-10
@@ -506,42 +506,18 @@
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
@@ -1404,7 +1380,6 @@ A continuant cannot have an occurrent as part: use 'participates in'.
regulates (processual)
false
-
regulates
@@ -1424,7 +1399,6 @@ A continuant cannot have an occurrent as part: use 'participates in'.
negatively regulates (process to process)
-
negatively regulates
@@ -1449,7 +1423,6 @@ A continuant cannot have an occurrent as part: use 'participates in'.
positively regulates (process to process)
-
positively regulates
@@ -3830,6 +3803,12 @@ For example, A and B may be gene products and binding of B by A positively regul
+
+
+
+
+
+
@@ -3851,7 +3830,7 @@ For example, A and B may be gene products and binding of B by A positively regul
-
+
The stage of the Drosophila life-cycle from fertilization to hatching.
@@ -5412,6 +5391,7 @@ For example, A and B may be gene products and binding of B by A positively regul
The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).
+ UBERON:8000000
L1
first instar larva
FlyBase_development_CV
@@ -5445,6 +5425,7 @@ For example, A and B may be gene products and binding of B by A positively regul
The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).
+ UBERON:8000001
L2
second instar larva
FlyBase_development_CV
@@ -5478,6 +5459,7 @@ For example, A and B may be gene products and binding of B by A positively regul
The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).
+ UBERON:8000002
L3
FlyBase_development_CV
third instar larva
@@ -9924,7 +9906,7 @@ For example, A and B may be gene products and binding of B by A positively regul
A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
- GOC:pdt
+ GOC:pdt
diff --git a/fly_development.obo b/fly_development.obo
index eaf1f12..980be52 100644
--- a/fly_development.obo
+++ b/fly_development.obo
@@ -1,6 +1,6 @@
format-version: 1.2
-data-version: 2021-01-13
-date: 13:01:2021 12:26
+data-version: 2021-03-10
+date: 10:03:2021 10:39
subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation"
subsetdef: gocheck_do_not_manually_annotate "Term not to be used for direct manual annotation"
subsetdef: goslim_aspergillus "Aspergillus GO slim"
@@ -315,6 +315,7 @@ comment: Temporal ordering number - 10.
is_a: FBdv:00005259 ! developmental stage
relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
relationship: substage_of FBdv:00005286 ! egg stage
+relationship: substage_of FBdv:00005289 ! embryonic stage
[Term]
id: FBdv:00005289
@@ -322,7 +323,7 @@ name: embryonic stage
def: "The stage of the Drosophila life-cycle from fertilization to hatching." [FBC:DOS]
comment: Temporal ordering number - 20.
is_a: FBdv:00007012 ! life stage
-relationship: immediately_preceded_by FBdv:00005288 ! fertilized egg stage
+relationship: immediately_preceded_by FBdv:00005287 ! unfertilized egg stage
[Term]
id: FBdv:00005290
@@ -768,6 +769,7 @@ def: "The first larval instar begins at hatching and ends at the first larval mo
comment: Temporal ordering number - 410.
synonym: "first instar larva" EXACT []
synonym: "L1" EXACT []
+xref: UBERON:8000000
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005289 ! embryonic stage
relationship: immediately_preceded_by FBdv:00005333 ! late embryonic stage
@@ -782,6 +784,7 @@ def: "The second larval instar begins at the first larval molt and ends at the s
comment: Temporal ordering number - 420.
synonym: "L2" EXACT []
synonym: "second instar larva" EXACT []
+xref: UBERON:8000001
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005337 ! first instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -793,6 +796,7 @@ def: "The third larval instar begins at the second larval molt and ends at pupar
comment: Temporal ordering number - 430.
synonym: "L3" EXACT []
synonym: "third instar larva" RELATED []
+xref: UBERON:8000002
is_a: FBdv:00007012 ! life stage
relationship: immediately_preceded_by FBdv:00005338 ! second instar larval stage
relationship: substage_of FBdv:00005336 ! larval stage
@@ -1991,6 +1995,7 @@ relationship: substage_of FBdv:00005321 ! extended germ band stage
id: ends_at_start_of
name: ends_at_start_of
comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)
+subset: ro-eco
xref: RO:0002090
[Typedef]
@@ -2000,6 +2005,7 @@ comment: X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X))
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_go_ontology
subset: http://purl.obolibrary.org/obo/valid_for_gocam
+subset: ro-eco
xref: RO:0002092
is_transitive: true
@@ -2037,6 +2043,7 @@ name: overlaps
def: "x overlaps y if and only if there exists some z such that x has part z and z part of y" []
subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension
subset: http://purl.obolibrary.org/obo/valid_for_gocam
+subset: ro-eco
xref: RO:0002131
holds_over_chain: has_part overlaps
@@ -2045,6 +2052,7 @@ id: preceded_by
name: preceded_by
namespace: relationship
def: "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." []
+subset: ro-eco
xref: BFO:0000062
xref_analog: OBO_REL:preceded_by
holds_over_chain: happens_during preceded_by
diff --git a/imports/go_import.obo b/imports/go_import.obo
index 0be8162..5a7c5d1 100644
--- a/imports/go_import.obo
+++ b/imports/go_import.obo
@@ -1,5 +1,5 @@
format-version: 1.2
-data-version: fbdv/releases/2021-01-13/imports/go_import.owl
+data-version: fbdv/releases/2021-03-10/imports/go_import.owl
subsetdef: gocheck_do_not_annotate ""
subsetdef: gocheck_do_not_manually_annotate ""
subsetdef: goslim_agr ""
@@ -16,7 +16,8 @@ subsetdef: goslim_plant ""
subsetdef: goslim_pombe ""
subsetdef: goslim_yeast ""
ontology: fbdv/imports/go_import
-property_value: owl:versionInfo "2021-01-13" xsd:string
+property_value: http://purl.org/dc/elements/1.1/source http://purl.obolibrary.org/obo/go/releases/2021-02-01/go.owl
+property_value: owl:versionInfo "2021-03-10" xsd:string
[Term]
id: GO:0000087
diff --git a/imports/go_import.owl b/imports/go_import.owl
index c31e201..89f7fb6 100644
--- a/imports/go_import.owl
+++ b/imports/go_import.owl
@@ -1,6 +1,7 @@
-
- 2021-01-13
+
+
+ 2021-03-10
@@ -650,7 +652,7 @@
A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
- GOC:pdt
+ GOC:pdt
diff --git a/imports/ro_import.obo b/imports/ro_import.obo
index ffbe29b..6c59b5e 100644
--- a/imports/ro_import.obo
+++ b/imports/ro_import.obo
@@ -1,5 +1,5 @@
format-version: 1.2
-data-version: fbdv/releases/2021-01-13/imports/ro_import.owl
+data-version: fbdv/releases/2021-03-10/imports/ro_import.owl
subsetdef: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension ""
subsetdef: http://purl.obolibrary.org/obo/valid_for_go_gp2term ""
subsetdef: http://purl.obolibrary.org/obo/valid_for_go_ontology ""
@@ -7,7 +7,8 @@ subsetdef: http://purl.obolibrary.org/obo/valid_for_gocam ""
subsetdef: ro-eco ""
subsetdef: RO:0002259 ""
ontology: fbdv/imports/ro_import
-property_value: owl:versionInfo "2021-01-13" xsd:string
+property_value: http://purl.org/dc/elements/1.1/source http://purl.obolibrary.org/obo/ro/releases/2021-03-08/ro.owl
+property_value: owl:versionInfo "2021-03-10" xsd:string
owl-axioms: Prefix(owl:=)\nPrefix(rdf:=)\nPrefix(xml:=)\nPrefix(xsd:=)\nPrefix(rdfs:=)\n\n\nOntology(\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(Class())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(ObjectProperty())\nDeclaration(AnnotationProperty())\n\n\n\n############################\n# Classes\n############################\n\n# Class: (continuant)\n\nDisjointClasses( ObjectSomeValuesFrom( ))\n\n# Class: (occurrent)\n\nDisjointClasses( ObjectSomeValuesFrom( ))\n\n# Class: (kinase activity)\n\nSubClassOf( ObjectHasSelf())\n\n\nSubClassOf(ObjectSomeValuesFrom( ) ObjectUnionOf(ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )))))\nSubObjectPropertyOf(ObjectPropertyChain( ) )\nSubObjectPropertyOf(ObjectPropertyChain( ) )\nSubObjectPropertyOf(ObjectPropertyChain( ) )\nSubObjectPropertyOf(ObjectPropertyChain( ) )\nSubObjectPropertyOf(ObjectPropertyChain( ) )\nDLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ClassAtom( Variable()) ClassAtom( Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation( \"true\"^^xsd:boolean) Annotation(rdfs:comment \"MF(X)-directly_regulates->MF(Y)-enabled_by->GP(Z) => MF(Y)-has_input->GP(Y) e.g. if 'protein kinase activity'(X) directly_regulates 'protein binding activity (Y)and this is enabled by GP(Z) then X has_input Z\"^^xsd:string) Annotation(rdfs:label \"infer input from direct reg\"^^xsd:string) Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()) ClassAtom( Variable()) ClassAtom( Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:comment \"GP(X)-enables->MF(Y)-has_part->MF(Z) => GP(X) enables MF(Z),\ne.g. if GP X enables ATPase coupled transporter activity' and 'ATPase coupled transporter activity' has_part 'ATPase activity' then GP(X) enables 'ATPase activity'\") Annotation(rdfs:label \"enabling an MF enables its parts\") Body(ClassAtom( Variable()) ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation( \"true\"^^xsd:boolean) Annotation(rdfs:comment \"GP(X)-enables->MF(Y)-part_of->BP(Z) => GP(X) involved_in BP(Z) e.g. if X enables 'protein kinase activity' and Y 'part of' 'signal tranduction' then X involved in 'signal transduction'\"^^xsd:string) Annotation(rdfs:label \"involved in BP\"^^xsd:string) Body(ClassAtom( Variable()) ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ClassAtom( Variable()) ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:comment \"This rule is dubious: added as a quick fix for expected inference in GO-CAM. The problem is most acute for transmembrane proteins, such as receptors or cell adhesion molecules, which have some subfunctions inside the cell (e.g. kinase activity) and some subfunctions outside (e.g. ligand binding). Correct annotation of where these functions occurs leads to incorrect inference about the location of the whole protein. This should probably be weakened to \\\"... -> overlaps\\\"\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:comment \"If a molecular function (X) has a regulatory subfunction, then any gene product which is an input to that subfunction has an activity that directly_regulates X. Note: this is intended for cases where the regaultory subfunction is protein binding, so it could be tightened with an additional clause to specify this.\") Annotation(rdfs:label \"inferring direct reg edge from input to regulatory subfunction\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:label \"inferring direct neg reg edge from input to regulatory subfunction\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:label \"inferring direct positive reg edge from input to regulatory subfunction\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:label \"effector input is compound function input\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:label \"Input of effector is input of its parent MF\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:comment \"if effector directly regulates X, its parent MF directly regulates X\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:comment \"if effector directly positively regulates X, its parent MF directly positively regulates X\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:label \"if effector directly negatively regulates X, its parent MF directly negatively regulates X\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable())))\nDLSafeRule(Annotation(rdfs:label \"'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ClassAtom(owl:Nothing Variable()) ClassAtom(owl:Nothing Variable())))\nDLSafeRule(Annotation(rdfs:label \"'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).\") Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ClassAtom(owl:Nothing Variable(