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DESCRIPTION
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Package: surrosurv
Type: Package
Title: Evaluation of Failure Time Surrogate Endpoints in Individual Patient Data
Meta-Analyses
Version: 1.1.26
Authors@R: c(
person("Federico", "Rotolo", role="aut", email="[email protected]",
comment = c(ORCID = "0000-0003-4837-6501")),
person("Xavier", "Paoletti", role="ctb"),
person("Marc", "Buyse", role="ctb"),
person("Tomasz", "Burzykowski", role="ctb"),
person("Stefan", "Michiels", role="ctb", email="[email protected]",
comment = c(ORCID = "0000-0002-6963-2968")),
person("Dan", "Chaltiel", role="cre", email="[email protected]",
comment = c(ORCID = "0000-0003-3488-779X")))
Maintainer: Dan Chaltiel <[email protected]>
Description: Provides functions for the evaluation of
surrogate endpoints when both the surrogate and the true endpoint are failure
time variables. The approaches implemented are:
(1) the two-step approach (Burzykowski et al, 2001) <DOI:10.1111/1467-9876.00244> with a copula model (Clayton, Plackett, Hougaard) at
the first step and either a linear regression of log-hazard ratios at the second
step (either adjusted or not for measurement error);
(2) mixed proportional hazard models estimated via mixed Poisson GLM
(Rotolo et al, 2017 <DOI:10.1177/0962280217718582>).
Depends:
R (>= 3.5.0)
Imports:
copula,
eha,
grDevices,
lme4,
MASS,
Matrix,
msm,
mvmeta,
optimx,
parallel,
parfm,
stats,
survival
License: GPL-2
URL: https://github.com/Oncostat/surrosurv
BugReports: https://github.com/Oncostat/surrosurv/issues/
VignetteBuilder: R.rsp
Suggests:
R.rsp,
testthat (>= 3.0.0)
Encoding: UTF-8
Config/testthat/edition: 3