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index.html
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<!DOCTYPE html>
<html>
<head>
<meta charset="UTF-8">
<title>mitoPADdb - Mitochondrial Proteins Associated with Diseases database</title>
<link rel = "stylesheet" type = "text/css" href = "css/main.css" />
<style>
.intro{
width:80%;
height:auto;
margin:0 10% 0 10%;
}
</style>
<script>
function pasteQuery(queryKey, queryValue, index) {
document.getElementById('key'+index).value = queryKey;
document.getElementById('v'+index).value = queryValue;
}
</script>
</head>
<body>
<div class = "section_header">
<center><p class="title">mitoPADdb - Mitochondrial Proteins Associated with Diseases database</p></center>
</div>
<div class = "section_menu">
<center>
<table cellpadding="3px">
<tr class="nav">
<td class="nav"><a href="#" class="active">Home</a></td>
<td class="nav"><a href="browse.html" class="side_nav">Browse</a></td>
<td class="nav"><a href="statistics.html" class="side_nav">Statistics</a></td>
<td class="nav"><a href="help.html" class="side_nav">Help</a></td>
<td class="nav"><a href="team.html" class="side_nav">Team</a></td>
</tr>
</table>
</center>
</div>
<!--<div class = "section_left"></div>-->
<div class = "section_middle">
<br/>
<p class="intro" style="text-align:justify;">
The mitoPADdb is a manually curated database that provides comprehensive information on
810 mitochondrial protein-encoding (MPE) genes associated with 1793 disease terms. It
contains information on mutations and expressional variations of MPE genes at both the
mRNA and protein levels. The database classifies the diseases linked with mitochondrial
proteins into 14 broad categories. It allows users to access the data using (I) by search
option with <b>Gene symbol</b> or <b>UniProt accession</b> and (II) by browse options.
The search option provides information about 18356 mutations, 1284 expressional variations
(mRNA and protein levels) with experimental samples and techniques, and associated diseases
with source identifiers. The browse option allows users to access these data along with
disease-gene-pathway links and differential genes’ expression heatmap across 317 disease
studies, in five ways: <b>1) Gene symbol, 2) Pathway name, 3) Disease category name,
4) Disease category-wise MPE gene expression heatmap, and 5) Disease category-pairwise
comparison of MPE gene expression heatmap</b>.
</p><br/>
<p class="intro" style="font-size:1em;color:maroon;">
<b>Cite as:</b> Das, J., Bhattacharjee, S., & Saha, S. (2024).
mitoPADdb: A database of mitochondrial proteins associated with diseases. <i>Mitochondrion</i>,
78, 101927.
<a class="link" href="https://doi.org/10.1016/j.mito.2024.101927" target="_blank">https://doi.org/10.1016/j.mito.2024.101927</a>
Available online at:
<a class="link" href="https://authors.elsevier.com/c/1jLyP5aTPdCrfI" target="_blank">https://authors.elsevier.com/c/1jLyP5aTPdCrfI</a>
(This link is valid till August 20, 2024).
</p>
<!-- <br/> -->
<center><br/><h3>Search MitoPADdb</h3></center>
<form method="get" action="protein.php">
<!--<br/><center><button type="button" onclick="update_label()">Show Current Logical Query</button></center><br/>-->
<table class="form" id="form_input_table1" border="0" align="center">
<tr><td colspan="2" style="text-align:left;">Search by gene symbol or UniProt accession ID</td></tr>
<tr>
<td>
<font color = "red">*</font>
<select class="full" id="key1" name="keytype">
<option value="Any" selected>Any (UniProt accession ID or Gene symbol)</option>
<option value="ID">UniProt accession ID</option>
<option value="Name">Gene symbol</option>
</select>
</td>
<td><input class="full" type="text" id="v1" name="key" placeholder="Enter search keyword" required /></td>
</tr>
</table>
<div style="width:80%;margin:0 10% 0 10%;padding-left:1%;font-size:0.8em;">
<b>Example</b><br/>
Gene symbols:
<a class="link" href="#form_input_table1" onclick="pasteQuery('Name', 'FXN', 1)">FXN</a>,
<a class="link" href="#form_input_table1" onclick="pasteQuery('Name', 'NDUFB11', 1)">NDUFB11</a>;
UniProt accession IDs:
<a class="link" href="#form_input_table1" onclick="pasteQuery('ID', 'P00846', 1)">P00846</a>,
<a class="link" href="#form_input_table1" onclick="pasteQuery('ID', 'P00395', 1)">P00395</a>
</div>
<table border="0" align="center">
<tr>
<td style="text-align:right;//padding-right:100px;"><input type="submit" style="width:130px;margin:15px;//border-radius:10px;" /></td>
<td style="text-align:left;//padding-left:100px;"><button type="reset" class="noclass" style="width:130px;margin:15px;" value="Reset">Reset</button></td>
</tr>
</table>
</form>
<br/><hr/>
<p style="font-size:0.9em;text-align:center;">
© 2024 Bose Institute. All rights reserved. For queries, please contact Dr. Sudipto Saha
(<a class="link" href="mailto:[email protected]">[email protected]</a>,
<a class="link" href="mailto:[email protected]">[email protected]</a>).
</p>
<!--<form method="post" action="search_result.php">
<table class="form" id="form_input_table2" border="0" align="center">
<tr><td colspan="2" style="text-align:left;">2. Search by disease</td></tr>
<tr>
<td>
<font color = "red">*</font>
<select class="full" id="key2" name="key">
<option value="DiseaseName" selected>Disease Name</option>
<option value="OMIM">OMIM</option>
</select>
</td>
<td><input class="full" type="text" id="v2" name="value" placeholder="Enter search keyword" required /></td>
<input class="full" type="hidden" name="type" value="D" />
</tr>
</table>
<div style="text-align:center;width:100%;font-size:0.8em;">
Example: <a href="#form_input_table2" onclick="pasteQuery('DiseaseName', 'Parkinson', 2)">Parkinson</a>,
<a href="#form_input_table2" onclick="pasteQuery('OMIM', '605909', 2)">605909</a>,
<a href="#form_input_table2" onclick="pasteQuery('OMIM', '168600', 2)">168600</a>
</div>
<table border="0" align="center">
<tr>
<td style="text-align:right;//padding-right:100px;"><input type="submit" style="width:100px;margin:15px;//border-radius:10px;" name="Submit" value="Submit" /></td>
<td style="text-align:left;//padding-left:100px;"><button type="reset" class="noclass" style="width:100px;margin:15px;" value="Reset">Reset</button></td>
</tr>
</table>
</form>-->
</div>
</body>
</html>