DESCRIPTION

Package: eQTpLot
Title: Visualization of Colocalization Between eQTL and GWAS Data
Version: 0.0.0.9000
Authors@R: 
    c(person(given = "Theodore",
             family = "Drivas",
             role = "aut",
             email = "theodore.drivas@gmail.com"),
      person(given = "Anastasia",
	     family = "Lucas",
	     role = "cre",
	     email = "anastasia.lucas.bioinfo@gmail.com"))
Description: eQTpLot is an R package developed for the visualization of colocalization between 
             eQTL and GWAS data. It requires a number of R packages (biomaRt , dplyr, GenomicRanges, 
             ggnewscale, ggplot2, ggpubr, gridExtra, Gviz, patchwork) and takes as input two data frames 
             (one of GWAS data, and the other of eQTL data), with the user specififying the name of the 
             gene to be analyzed, the GWAS trait to be analyzed (useful if the GWAS data contains information 
             on multiple associations, as one might obtain from a PheWAS), and the tissue type to use for 
             the eQTL analysis (useful if eQTL data is available on multiple tissue types. A PanTissue 
             analysis can be specified as well, combining data across tissue types for each variant). 
             Additional parameters may be specified, including the p-value thresholds for GWAS or eQTL significance, 
             the genomic range to be displayed, axis/layout modifications for the resultant graphs, etc. This data 
             is then used to generate and output a series of plots visualizing colocalization, correlation, and 
             enrichment between eQTL and GWAS signals for a given gene-trait pair.
License: GPL-3
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.1.1
Imports: 
    dplyr,
    patchwork,
    gridExtra,
    Gviz,
    ggnewscale,
    GenomicRanges,
    biomaRt,
    ggpubr,
    ggplotify,
    LDheatmap,
    viridisLite
Depends: 
    ggplot2 (>= 3.3.0),
    R (>= 3.5.0)