Why the GRN Network is not complete? #303
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wariobrega
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* General SCENIC questions
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Dear SCENIC community,
I have a curiosity regarding the resulting output of the GRN (from GRNBoost2):
I was of the opinion that, for each TF-Target pair, I would have a pair in the GRN Inference step.
When I look at the network, however, I see that the majority of the TF -> Target links are not present. In Fact, if I try to compute the network density for the "complete" network (before RCisTarget), I obtain that the density is indeed quite low (0.6, dense, but not "that dense").
What is the explanation for this behaviour? Does GRNBoost does some filtering on the TF/Targets expression?
Thanks a lot!
Daniele
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