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<html><head>
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<title>Alex Felmeister</title>
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<p class="text-justify" id="abouttext">I am a PhD candidate at
<a href="http://www.drexel.edu">Drexel University</a> in Information Studies and Informatics at the
<a href="http://cci.drexel.edu">College of Computing and Informatics</a> where I work under the advisement of
<a href="http://cci.drexel.edu/faculty/thu/">Dr. Tony Hu</a>. I am also a Supervisor for Data Integration at
<a href="http://www.chop.edu"> The Children's Hospital of Philadelphia</a> (CHOP),
<a href="http://dbhi.chop.edu">Department of Biomedical
and Health Informatics</a> (DBHi) where I lead the effort in the development, implementation
and integration of the informatics infrastructure designed to support complex
biorepositories for both specific translational research projects and cross-institutional
efforts. </p>
<p>Academic interests include:
<u>Translational Bioinformatics</u>,
<u>Biomedical Informatics</u>,
<u>scientific software integration</u>,
<u>data driven application development</u>,
<u>data modeling</u>,
<u>data mining</u> and
<u>genomic, clinical and specimen data integration</u>.</p>
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<h4>News and Upcoming Activity</h4>
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<p>Publication!</p>
<p>Felmeister, A. S., Masino, A. J., Rivera, T. J., Resnick, A. C., and Jeffrey, W. (2016). The biorepository portal toolkit : An honest brokered , modular service oriented software tool set for biospecimen-driven translational research. BMC Genomics, 17(Suppl 4), 1–22. http://doi.org/10.1186/s12864-016-2797-9
</p>
<p>
<a href="https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-2797-9" target="_blank">Link to Journal</a>
</p>
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<li class="list-group-item">
<p>Presenting at CHI's 8th International Leaders in Biobanking Congress 2016
in Balimore, MD. September 7-9, 2016</p>
<p>
<a href="http://www.healthtech.com/biobanking/agenda/" target="_blank">Event Information</a>
</p>
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<p>Presentation recording from
<a href="www.odsc.com" target="_blank">ODSC</a>.</p>
<p>
<em>
<a href="https://www.opendatascience.com/conferences/odsc-east-2016-alex-felmeister-empowering-data-for-research-in-pediatric-brain-cancer/" target="_blank">ODSC East 2016 | Alex Felmeister – “Empowering Data for Research in Pediatric Brain Cancer”</a>
</em>
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<br>
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<p>
<em>2nd Annual Meeting of The Children’s Brain Tumor Tissue Consortium (CBTTC)</em>
</p>
<p></p>
<p>
<em>New Orleans, LA on May 24th and 25th, 2016.</em>
</p>
<p>
<em>
<em></em>
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</p>
<p>
<em>
<em>The CBTTC Investigator meeting will bring together the member institutions
and new institutions applying for membership including: Children’s Hospital
of Philadelphia, Seattle Children’s, Children’s Hospital of Pittsburgh
of UPMC, Ann and Robert H. Lurie Children’s Hospital of Chicago, and Meyer
Children’s Hospital in Florence, Italy, Stanford Children’s Hospital, UCSF’s
Benioff Children’s Hospital, Weill Cornell Children’s Hospital and Children’s
National Hospital in Washington, D.C. along with scientists, clinicians
and over 20 foundations.</em>
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</p>
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<a href="https://cbttc.org/news-and-events/" target="_blank">Event Information</a>
</p>
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<h4>Fantastic Experience
<a href="https://twitter.com/odsc" target="_blank">@ODSC</a>East</h4>
<h5>
<a href="http://www.odsc.com/boston/innovation/" target="_blank">Disruptive Data Science</a>
</h5>
<p>
<span>
<img src="images/alexodsceast2016.jpg">
</span>
</p>
</li>
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<h4>Presenting at ODSC (Open Data Science Conference) East</h4>
<h5>
<a href="http://www.odsc.com/boston/innovation/" target="_blank">Disruptive Data Science</a>
</h5>
<p>How Modern web technologies, data visualization and open data integration
tools can transform research in childhood cancer.</p>
<p>
<span>
<img src="http://www.odsc.com/wp-content/uploads/2015/10/faviODSC.png">
</span>
<a href="http://www.odsc.com/boston/" target="_blank">ODSC East </a>May 20-22 Boston Convention & Exhibition Center</p>
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<li class="list-group-item">
<h4>
<span class="glyphicon glyphicon-check checked"></span>Passed Preliminaries Candidacy Exam</h4>
</li>
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<h4>
<span class="glyphicon projection-screen"></span>Presenting at AMIA Joint Summits on Translational Science</h4>
<h5>Mar 21 - 24, 2016 in San Fran.</h5>
<p>Bringing Genomes Back to Biology: How Integration of Public Genomic Data
Sets with a Biorepository Translate Genomic Discoveries into Biological
Insight</p>
<a href="https://jointsummits2016.zerista.com/event/member/234728" target="_blank">More Info</a>
</li>
<li class="list-group-item">
<h4>Shout out about CHOP's Tissue Repository Infrastructure from the White
House!
<br>
<em>The Pressure is on!
<em></em>
</em>
</h4>
<em>
<em>
<a href="https://www.whitehouse.gov/the-press-office/2016/02/25/fact-sheet-obama-administration-announces-key-actions-accelerate" target="_blank">-White House Fact Sheet</a>
<br>
<button type="button" class="btn btn-success btn-xs" data-toggle="modal" data-target="#chopwhitehouse">From the Fact Sheet</button>
</em>
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<em>
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<h4>
<span class="glyphicon glyphicon-pencil"></span>Candidacy Exam Date Set</h4>
<h5>Defending my candidacy exam in the VERY near future.</h5>
<p>Hopefully soon I will no longer be a "doctoral student" but a PhD Candidate.
<br>Then the journey continues.
<br>Right now: reading and writing.</p>
</li>
<li class="list-group-item">
<h5>CHOP Announces New Center</h5>
<h4>Center for Data Driven Discovery in Biomedicine (D3b)</h4>
<p>Open-Data Empowerment: A new disruptive model in biomedical research that
will drive a new paradigm for precision medicine.</p>
<i>
<a href="http://blog.research.chop.edu/chop-launches-first-of-its-kind-center-for-data-driven-discovery-in-biomedicine-d3b/" target="_blank">More Info</a>
</i>
<p></p>
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<h5>Special Issue Invite in BMC Genomics</h5>
<p>Invited to expand IEEE conference paper to full journal article in a special
issue of BMC Genomics</p>
<p>
<i>This is a first!</i>
</p>
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<h4 class="modal-title" id="myModalLabel">Scalable Biobanking: A Modular Electronic Honest Broker and Biorepository
for Integrated Clinical, Specimen and Genomic Research</h4>
<h5>A Data Driven and Integrative Approach to Asychronous, Longitudinal and
Collaborative Specimen and Genomic Research</h5>
<p class="text-justify">
<i>Abstract</i>— Biorepository research has introduced significant challenges
to biomedical informatics systems design and implementation. We take a
best-of-breed system integrative approach to finding solutions to administer
a biobank operationally, use a biobank scientifically and integrate clinical,
specimen and genomic data. We introduce an electronic Honest Broker (eHB)
and Biorepository Portal (BRP) open source project that, in tandem, allow
for integration of data on the input and output while protecting subject
privacy, a primary issue in research and healthcare informatics. Research
data management systems like REDCap and our proprietary laboratory information
management system (LIMS) are used as best-of- breed client systems and
integrated with downstream genomic analyses. Taking this honest brokered
system-client based, modular approach to biorepository research, we allow
for data and specimens to be associated with a biorepository subject at
anytime point asynchronously, lowering the bar to develop new research
projects based on scientific merit and having a future proofed specimen
set for collaborative advanced genomic and tissue research yet to be established.
<br>
<a href="http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=7359732&isnumber=7359638 " target="_blank">View on IEEE Xplore</a>
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<h4 class="modal-title" id="myModalLabel">FACT SHEET: Obama Administration Announces Key Actions to Accelerate Precision
Medicine Initiative</h4>
<h5>In conjunction with today’s announcements, more than 40 private-sector
organizations are making commitments that will accelerate precision medicine,
in alignment with the key principles of the Precision Medicine Initiative</h5>
<p class="text-justify">
<i>The Children's Hospital of Philadelphia</i>—is announcing the launch of
a new Center for Data-Driven Discovery in Biomedicine (D3b). Working with
leading hospitals, industry partners, foundations, patients, and their
families, the Center will develop a
<u>multi-institutional biorepository infrastructure and data-analysis ecosystem
that supports patient participation in collaborative pediatric cancer tissue-based
research and a shared, open-data infrastructure that will drive precision
medicine discovery</u>. Integrated initiatives will support patients’ access,
use, and sharing of their own genomic and clinical data. These platforms,
which are undergoing comprehensive development in 2016, will help doctors
match cancer therapies to individual children and define new precision
medicine approaches for pediatric cancer and childhood diseases.
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