From cab225ca084f00f8380cd5030b9c6106e97125d5 Mon Sep 17 00:00:00 2001 From: Jake Hughey Date: Fri, 31 Aug 2018 10:33:55 -0500 Subject: [PATCH] fixed typo in vignette --- vignettes/polyester.Rmd | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/vignettes/polyester.Rmd b/vignettes/polyester.Rmd index c2d57c0..04239e6 100644 --- a/vignettes/polyester.Rmd +++ b/vignettes/polyester.Rmd @@ -83,7 +83,7 @@ The statistical model behind this function is a negative binomial distribution, - Fold changes will multiply these baseline mean numbers for the specified group. - Long transcripts usually produce more reads in RNA-seq experiments than short ones, so you may want to specify `reads_per_transcript` as a function of transcript length - Default is 300 (regardless of transcript length). -* `size`: controls the per-transcript mean/variance relationship. In the negative binomial distribution, the mean/variance relationship is: ```mean = mean + (mean^2) / size```. You can specify the size for each transcript. By default, size is defined as 1/3 of the transcript's mean, which (in our experience) creates an idealized, low-variance situation. Decrease the value of `size` to introduce more variance into your simulations. +* `size`: controls the per-transcript mean/variance relationship. In the negative binomial distribution, the mean/variance relationship is: ```variance = mean + (mean^2) / size```. You can specify the size for each transcript. By default, size is defined as 1/3 of the transcript's mean, which (in our experience) creates an idealized, low-variance situation. Decrease the value of `size` to introduce more variance into your simulations. ### `simulate_experiment_countmat` example