From 35145955108e23d018f18c2c1170775e47da0eec Mon Sep 17 00:00:00 2001 From: gromdimon Date: Wed, 15 Nov 2023 11:02:10 +0100 Subject: [PATCH] feat: new info in about page --- frontend/src/views/AboutView.vue | 48 ++++++++++++++++++++++++++++++-- 1 file changed, 45 insertions(+), 3 deletions(-) diff --git a/frontend/src/views/AboutView.vue b/frontend/src/views/AboutView.vue index c55691c1..e9ee91c4 100644 --- a/frontend/src/views/AboutView.vue +++ b/frontend/src/views/AboutView.vue @@ -51,9 +51,45 @@ const Acknowledgements: AcknowledgementsType = { researcher investigating rare diseases, REEV is here to streamline your workflow. Our platform combines cutting-edge technology with user-friendly interfaces to ensure that you have the resources you need to make informed decisions. -

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+

Sequence Variants in REEV

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+ REEV's documentation on ACMG Sequence Variant Criteria provides a comprehensive guide + for the automated classification of sequence variants. This process emphasizes + transparency for users, ensuring they receive detailed reports of evidence supporting + or contradicting each criterion. It is meticulously designed to inform users why + certain criteria are applied or omitted in specific cases, such as when one criterion + may invalidate others due to the nature of the variant (e.g., BA1 disabling all other + benign criteria). In addition, the ACMG Sequence Variant Details section elaborates on + the implementation of these classification criteria. This includes a detailed + description of the data sources utilized in the classification of sequence variants. + These sources form the foundation of the classification process, aiding in the + accurate and comprehensive evaluation of sequence variants. +

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Copy Number Variants in REEV

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+ The ACMG CNV Criteria section in REEV's documentation outlines the implementation of + criteria for CNVs (Copy Number Variants), based on guidelines from Riggs et al. + (2020). These criteria are critical for understanding and classifying CNVs in the + context of genetic analysis and rare disease research. Furthermore, the ACMG CNV + Details page provides in-depth information about the assessment criteria for CNVs. + This includes an overview of the data used for classification, emphasizing the + thorough and detailed approach REEV takes in evaluating CNVs. The data used in this + classification process is pivotal for understanding the genetic implications of CNVs + and their potential impact on rare genetic disorders. +

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+ Overall, REEV's approach to both sequence and CNV variants is characterized by a + meticulous and transparent methodology. The platform's use of comprehensive data + sources and adherence to established criteria ensures that it remains a valuable tool + for researchers and clinicians in the field of rare disease genetics. +

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+ For more detailed information, please visit our + documentation. +

+ + @@ -92,4 +128,10 @@ const Acknowledgements: AcknowledgementsType = { font-size: 16px; margin-bottom: 20px; } + +.subtitle { + font-size: 18px; + font-weight: bold; + margin-bottom: 10px; +}