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Investigate performance and AC+AF cutoffs for LD Code #756

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matren395 opened this issue Jan 23, 2025 · 0 comments
Open

Investigate performance and AC+AF cutoffs for LD Code #756

matren395 opened this issue Jan 23, 2025 · 0 comments
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@matren395
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Find appropriate AC and/or AF cutoff for LD data , such that the code does not encounter out-of-memory issues.

Wenhan mentioned errors at 10 million variants per run (so per genetic ancestry group) but prior gnomAD v2 code mentioned the same at 30 million variants , both on standard workers ? where will I encounter this when running ?

And for cutoffs, we are running on both NFE and AFR. Is there the same cutoff that would get appropriate numbers (Wenhan ballparked 7-9million) for both ?

Relevant to #1656

@matren395 matren395 self-assigned this Jan 23, 2025
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