diff --git a/main.c b/main.c
index 4b50c1a..7c0ed4d 100644
--- a/main.c
+++ b/main.c
@@ -76,7 +76,7 @@ typedef struct _mpzobject {
 
 PyTypeObject MPZ_Type;
 
-#if !defined(PYPY_VERSION)
+#if !defined(PYPY_VERSION) && !Py_GIL_DISABLED
 #  define CACHE_SIZE (99)
 #else
 #  define CACHE_SIZE (0)
diff --git a/pyproject.toml b/pyproject.toml
index 10657bb..d71c81a 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -55,7 +55,7 @@ version = {attr = "setuptools_scm.get_version"}
 "*" = ["*.h"]
 
 [project.optional-dependencies]
-tests = ["pytest", "hypothesis<=6.123.2"]
+tests = ["pytest", "hypothesis<=6.123.4"]
 docs = ["sphinx"]
 develop = ["python-gmp[tests,docs]", "pre-commit", "pyperf",
            "gmpy2>=2.2; platform_python_implementation!='PyPy'",