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[TERM REQUEST] Hydroxyl group (functionalization of surface) #543

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jmillanacosta opened this issue Mar 19, 2024 · 1 comment · Fixed by #661
Closed
Tracked by #558

[TERM REQUEST] Hydroxyl group (functionalization of surface) #543

jmillanacosta opened this issue Mar 19, 2024 · 1 comment · Fixed by #661
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@jmillanacosta
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What would you use as label or labels for the terms?
hydroxyl group, hydroxy

What is the definition of the term?
Functional group comprised of one oxygen atom covalently bonded to one hydrogen atom

Is there an ontology that has this term?
ChEBI

Additional context
These groups can be found in the surface of GO

https://doi.org/10.3390/ijms221910578

In our study, compared to the untreated GO, the UV-treated GO possessed higher carboxyl (C-COOH) and carbon-carbon groups (C-C and C=C), lower epoxy (C-O-C) and hydroxyl (C-OH) functional groups, and similar oxygen content (Table 1). These features might contribute to the significantly higher molecular toxicity related to DNA damage stress, protein stress, and chemical stress.

Discuss whether to add the class as a surface functionalization of nanoparticle (http://purl.bioontology.org/ontology/npo#NPO_1883).

What ontology design patterns should be followed for surface functionalizations?

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Available IRI: http://purl.enanomapper.net/onto/ENM_6674110

@jmillanacosta jmillanacosta linked a pull request Mar 21, 2024 that will close this issue
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