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Different outputs #2

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oliveira-lab opened this issue Apr 25, 2017 · 1 comment
Open

Different outputs #2

oliveira-lab opened this issue Apr 25, 2017 · 1 comment

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@oliveira-lab
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I have tested the web based implementation of QGRS for the following sequence (default parameters):
GGGCTGGGGGCTGGGGGCTGGGGGCTGGGGGCTGGGGGCTGGGGGCTGGGGGCTGGAGGCTGGGGGCTGG

I get as output 2 sequences starting at positions 6 and 35.

Then I tested it with the C++ implementation (default parameters) and I just got one hit:
1 5 12 19 26 5 96 GGGGGCTGGGGGCTGGGGGCTGGGGG

Why these differences?
Also, if I extend this sequence to something larger (1 kb) and full of G4s, it takes almost 4 hours to run (with no overlap)...

Could you please help me?
Thanks

@KevinMcKernan
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I'm trying to run this across a 876Mb Genome and Im getting a Core Dump.
Is this too big of an input file?

./qgrs -csv -i /JL_No_Ns.fasta -o G-quadraplex_JLion_NoN.csv
terminate called after throwing an instance of 'std::bad_alloc'
what(): std::bad_alloc
Aborted (core dumped)

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