forked from sadicelik/DrugBank-Web-Scraper
-
Notifications
You must be signed in to change notification settings - Fork 0
/
Copy pathpharmaco-metabolomics-page21_markup.html
234 lines (234 loc) · 64.4 KB
/
pharmaco-metabolomics-page21_markup.html
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
<!DOCTYPE html><html class="turbolinks-progress-bar"><head><meta content="width=device-width, initial-scale=1, shrink-to-fit=no" name="viewport"><meta content="text/html; charset=UTF-8" http-equiv="Content-Type"><meta content="fdhmwDBTGwNPe0lKcJVly7AToLfZYvJ-mtjFAPTMZGs" name="google-site-verification"><meta content="296E0FF6379AE64A0D18C39BB40ECD6E" name="msvalidate.01"><title>Pharmaco-metabolomics | DrugBank Online</title><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon-57x57-precomposed.png" sizes="57x57"><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon-60x60-precomposed.png" sizes="60x60"><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon-72x72-precomposed.png" sizes="72x72"><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon-76x76-precomposed.png" sizes="76x76"><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon-114x114-precomposed.png" sizes="114x114"><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon-120x120-precomposed.png" sizes="120x120"><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon-144x144-precomposed.png" sizes="144x144"><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon-152x152-precomposed.png" sizes="152x152"><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon-180x180-precomposed.png" sizes="180x180"><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon-precomposed.png" sizes="57x57"><link rel="apple-touch-icon" type="image/x-icon" href="/favicons/apple-touch-icon.png" sizes="57x57"><link rel="icon" type="image/png" href="/favicons/favicon-96x96.png" sizes="96x96"><link rel="icon" type="image/png" href="/favicons/favicon-32x32.png" sizes="32x32"><link rel="icon" type="image/png" href="/favicons/favicon-16x16.png" sizes="16x16"><link rel="icon" type="image/png" href="/favicons/favicon.png" sizes="16x16"><link rel="shortcut icon" type="image/x-icon" href="/favicons/favicon.ico"><meta content="#da532c" name="msapplication-TileColor"><meta content="/favicons/mstile-144x144.png" name="msapplication-TileImage"><meta content="#ffffff" name="theme-color"><meta content="DrugBank" name="application-name"><link as="font" crossorigin="" href="/assets/GemeliWeb-Regular-9ccb07b090f3aef673e3b29ba66e2e685ccf3d438e550624d9739f1bd5164cb2.woff2" rel="preload" type="font/woff2"><link as="font" crossorigin="" href="/assets/GemeliWeb-Bold-f344ff98a063f8cb6ac490b132bda4035ecc8984358dfa8d9bd8621fa38744e2.woff2" rel="preload" type="font/woff2"><link as="font" crossorigin="" href="/assets/GemeliWeb-Light-8227f53ee1957ae57cc0c81d1cfecb59238e3fd9d32b1e792432e1f8c81784a1.woff2" rel="preload" type="font/woff2"><link as="style" data-turbolinks-track="true" href="/assets/public_preload-ec9281ddba7498de9953c0f69a4b77e3e6b7f8f23fe47e1c347b028af890fc0e.css" media="all" onload="this.onload=null;this.rel='stylesheet'" rel="stylesheet"><noscript><link href="/assets/public_preload-ec9281ddba7498de9953c0f69a4b77e3e6b7f8f23fe47e1c347b028af890fc0e.css" media="all" rel="stylesheet" /></noscript><link rel="stylesheet" media="all" href="/assets/public-720199d14ecb75df792c22a0b89a1e5817dab39ae1fda73ea0da1c4d7f67510b.css" data-turbolinks-track="true"><script type="text/javascript" async="" src="https://www.googleadservices.com/pagead/conversion_async.js"></script><script type="text/javascript" async="" src="https://snap.licdn.com/li.lms-analytics/insight.min.js"></script><script async="" src="https://d.clarity.ms/s/0.6.27/clarity.js"></script><script src="https://js.hsadspixel.net/fb.js" type="text/javascript" id="hs-ads-pixel-2224137" data-ads-portal-id="2224137" data-ads-env="prod" data-loader="hs-scriptloader" data-hsjs-portal="2224137" data-hsjs-env="prod" data-hsjs-hublet="na1"></script><script src="https://js.hs-banner.com/2224137.js" type="text/javascript" id="cookieBanner-2224137" data-cookieconsent="ignore" data-hs-ignore="true" data-loader="hs-scriptloader" data-hsjs-portal="2224137" data-hsjs-env="prod" data-hsjs-hublet="na1"></script><script src="https://js.hs-analytics.net/analytics/1636197900000/2224137.js" type="text/javascript" id="hs-analytics"></script><script async="" src="//www.google-analytics.com/analytics.js"></script><script async="" src="https://www.clarity.ms/tag/5600r08mxy"></script><script src="/assets/public-27f932f135aadc4b526264005f1d5e85b32bfbdf9c790701e4b7be02cb9db204.js" media="all" data-turbolinks-track="true" defer="defer"></script><script>(function(c,l,a,r,i,t,y){
c[a]=c[a]||function(){(c[a].q=c[a].q||[]).push(arguments)};
t=l.createElement(r);t.async=1;t.src="https://www.clarity.ms/tag/"+i;
y=l.getElementsByTagName(r)[0];y.parentNode.insertBefore(t,y);
})(window, document, "clarity", "script", "5600r08mxy");</script><meta name="csrf-param" content="authenticity_token">
<meta name="csrf-token" content="6wP6YS3kDi/9CnZdHtnWGKXzCgjZrS2E/CiDR25j3XZteycG2ZAyQ7/WDfRAp0GoYeKi6eh28rRYJ22H/76n9w=="><style>html.turbolinks-progress-bar::before {
content: '';
position: fixed;
top: 0;
left: 0;
z-index: 2000;
background-color: #0076ff;
height: 3px;
opacity: 0.99;
width: 0%;
transition: width 300ms ease-out, opacity 150ms ease-in;
transform: translate3d(0,0,0);
}</style><script async="" src="https://www.googletagmanager.com/gtag/js?id=AW-704543816"></script><script src="https://googleads.g.doubleclick.net/pagead/viewthroughconversion/704543816/?random=1636198079027&cv=9&fst=1636198079027&num=1&bg=ffffff&guid=ON&resp=GooglemKTybQhCsO&eid=376635471&u_h=720&u_w=1280&u_ah=720&u_aw=1280&u_cd=24&u_his=23&u_tz=180&u_java=true&u_nplug=0&u_nmime=0&gtm=2oab31&sendb=1&ig=1&data=event%3Dgtag.config&frm=0&url=https%3A%2F%2Fgo.drugbank.com%2Fpharmaco%2Fmetabolomics%3Fpage%3D21&tiba=Pharmaco-metabolomics%20%7C%20DrugBank%20Online&hn=www.googleadservices.com&async=1&rfmt=3&fmt=4"></script></head><body class="pharmaco-metabolite-regulations-c index-a has-banner"><header><nav class="navbar fixed-top navbar-expand-custom navbar-light" id="main-nav" style="background-color: #ff00b8;"><a class="navbar-brand" href="/"><img style="width: 178px; height: 20px;" src="/assets/logo-white-dd185d748ee0164b8ee8f88df29235cd8cfc7936a3c974589262c667e9294219.svg" alt="Logo white"><div class="online">Online</div></a><button aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation" class="navbar-toggler navbar-toggler-right" data-target="#navbar" data-toggle="collapse" type="button"><span class="navbar-toggler-icon"></span></button><div class="collapse navbar-collapse" id="navbar"><ul class="navbar-nav ml-auto"><li class="nav-item dropdown"><a class="nav-link dropdown-toggle" data-toggle="dropdown" href="#">Browse</a><div class="dropdown-menu"><a class="dropdown-item" href="/drugs"><div class="icon-circle drugbank-icon icon-drugs"><svg class="icon" role="img" title="drugs">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#drugs"></use>
</svg>
</div> Drugs</a><a class="dropdown-item" href="/drugs/starred"><div class="icon-circle drugbank-icon icon-star"><svg class="icon" role="img" title="star">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#star"></use>
</svg>
</div> Starred Drugs</a><a class="dropdown-item" href="/categories"><div class="icon-circle drugbank-icon icon-categories"><svg class="icon" role="img" title="categories">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#categories"></use>
</svg>
</div> Categories</a><a class="dropdown-item" href="/pathways"><div class="icon-circle drugbank-icon icon-pathways"><svg class="icon" role="img" title="pathways">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#pathways"></use>
</svg>
</div> Pathways</a><a class="dropdown-item" href="/reactions"><div class="icon-circle drugbank-icon icon-reactions"><svg class="icon" role="img" title="reactions">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#reactions"></use>
</svg>
</div> Drug Reactions</a><a class="dropdown-item" href="/classyfication"><div class="icon-circle drugbank-icon icon-classifications"><svg class="icon" role="img" title="classifications">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#classifications"></use>
</svg>
</div> Drug Classification</a><a class="dropdown-item" href="/targets"><div class="icon-circle drugbank-icon icon-targets"><svg class="icon" role="img" title="targets">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#targets"></use>
</svg>
</div> Drug Targets</a><div class="dropdown-divider"></div><a class="dropdown-item" href="/pharmaco/genomics"><div class="icon-circle drugbank-icon icon-geno-browse"><svg class="icon" role="img" title="geno-browse">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#geno-browse"></use>
</svg>
</div> Pharmaco-genomics</a><a class="dropdown-item" href="/pharmaco/metabolomics"><div class="icon-circle drugbank-icon icon-chemquery"><svg class="icon" role="img" title="chemquery">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#chemquery"></use>
</svg>
</div> Pharmaco-metabolomics</a><a class="dropdown-item" href="/pharmaco/transcriptomics"><div class="icon-circle drugbank-icon icon-interax"><svg class="icon" role="img" title="interax">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#interax"></use>
</svg>
</div> Pharmaco-transcriptomics</a><a class="dropdown-item" href="/pharmaco/proteomics"><div class="icon-circle drugbank-icon icon-interax"><svg class="icon" role="img" title="interax">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#interax"></use>
</svg>
</div> Pharmaco-proteomics</a></div></li><li class="nav-item dropdown"><a class="nav-link dropdown-toggle" data-toggle="dropdown" href="#">COVID-19</a><div class="dropdown-menu"><a class="dropdown-item" href="/covid-19"><div class="icon-circle drugbank-icon icon-covid-overview"><svg class="icon" role="img" title="covid-overview">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#covid-overview"></use>
</svg>
</div> Overview</a><a class="dropdown-item" href="/covid-19-vaccination"><div class="icon-circle drugbank-icon icon-covid-vaccination"><svg class="icon" role="img" title="covid-vaccination">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#covid-vaccination"></use>
</svg>
</div> Vaccine Side Effects</a></div></li><li class="nav-item dropdown"><a class="nav-link dropdown-toggle" data-toggle="dropdown" href="#">Search</a><div class="dropdown-menu"><a data-no-turbolink="true" class="dropdown-item" href="/structures/search/small_molecule_drugs/structure"><div class="icon-circle drugbank-icon icon-chemquery"><svg class="icon" role="img" title="chemquery">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#chemquery"></use>
</svg>
</div> Chemical Structure</a><a data-no-turbolink="true" class="dropdown-item" href="/structures/search/small_molecule_drugs/mass"><div class="icon-circle drugbank-icon icon-molecular-weight"><svg class="icon" role="img" title="molecular-weight">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#molecular-weight"></use>
</svg>
</div> Molecular Weight</a><a class="dropdown-item" href="/drug-interaction-checker"><div class="icon-circle drugbank-icon icon-interax"><svg class="icon" role="img" title="interax">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#interax"></use>
</svg>
</div> Drug & Food Interactions</a><a class="dropdown-item" data-no-turbolink="true" href="/structures/search/bonds/sequence"><div class="icon-circle drugbank-icon icon-sequence"><svg class="icon" role="img" title="sequence">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#sequence"></use>
</svg>
</div> Target Sequences</a><a class="dropdown-item" data-no-turbolink="true" href="/pharmaco/search"><div class="icon-circle drugbank-icon icon-pathways"><svg class="icon" role="img" title="pathways">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#pathways"></use>
</svg>
</div> Pharmaco-omics</a><a class="dropdown-item" href="/unearth/advanced/drugs"><div class="icon-circle drugbank-icon icon-advanced"><svg class="icon" role="img" title="advanced">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#advanced"></use>
</svg>
</div> Advanced Search</a><div class="dropdown-divider"></div><a class="dropdown-item" href="/spectra/ms/search"><div class="icon-circle drugbank-icon icon-ms"><svg class="icon" role="img" title="ms">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#ms"></use>
</svg>
</div> MS Search</a><a class="dropdown-item" href="/spectra/ms_ms/search"><div class="icon-circle drugbank-icon icon-msms"><svg class="icon" role="img" title="msms">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#msms"></use>
</svg>
</div> MS/MS Search</a><a class="dropdown-item" href="/spectra/c_ms/search"><div class="icon-circle drugbank-icon icon-gcms"><svg class="icon" role="img" title="gcms">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#gcms"></use>
</svg>
</div> GC/MS Search</a><a class="dropdown-item" href="/spectra/nmr_one_d/search"><div class="icon-circle drugbank-icon icon-nmr-1d"><svg class="icon" role="img" title="nmr-1d">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#nmr-1d"></use>
</svg>
</div> 1D NMR Search</a><a class="dropdown-item" href="/spectra/nmr_two_d/search"><div class="icon-circle drugbank-icon icon-nmr-2d"><svg class="icon" role="img" title="nmr-2d">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#nmr-2d"></use>
</svg>
</div> 2D NMR Search</a></div></li><li class="nav-item"><a class="nav-link" href="/drug-interaction-checker">Interaction Checker</a></li><li class="nav-item"><a class="nav-link" href="/releases/latest">Downloads</a></li><li class="nav-item dropdown" role="presentation"><a class="nav-link dropdown-toggle" data-toggle="dropdown" href="#">Solutions</a><div class="dropdown-menu"><div class="link-header dropdown-item">Products</div><a class="dropdown-item" target="_blank" href="https://www.drugbank.com/clinical"><div class="icon-pink product-icon drugbank-icon icon-clinical"><svg class="icon" role="img" title="clinical"> <use xlink:href="/assets/plus/icons-cd39e90ea1c71389b36ffc9fc3f485bf2c6ab875ef9ea285614fcbd70cacf943.svg#clinical"> </use></svg></div> Clinical Drug API</a><a class="dropdown-item" target="_blank" href="https://www.drugbank.com/scientific"><div class="icon-pink product-icon drugbank-icon icon-scientific"><svg class="icon" role="img" title="scientific"> <use xlink:href="/assets/plus/icons-cd39e90ea1c71389b36ffc9fc3f485bf2c6ab875ef9ea285614fcbd70cacf943.svg#scientific"> </use></svg></div> Scientific Drug Data</a><div class="link-header dropdown-item">Industries</div><a class="dropdown-item" target="_blank" href="https://www.drugbank.com/use_cases/drug_discovery">Drug Discovery</a><a class="dropdown-item" target="_blank" href="https://www.drugbank.com/use_cases/drug_repurposing">Drug Repurposing</a><a class="dropdown-item" target="_blank" href="https://www.drugbank.com/use_cases/precision_medicine">Precision Medicine</a><a class="dropdown-item" target="_blank" href="https://www.drugbank.com/use_cases/machine_learning">Machine Learning</a><a class="dropdown-item" target="_blank" href="https://www.drugbank.com/use_cases/telehealth">Telehealth</a><a class="dropdown-item" target="_blank" href="https://www.drugbank.com/use_cases/electronic_medical_records">Electronic Medical Records</a><div class="link-header dropdown-item">Resources</div><a class="dropdown-item" target="_blank" href="https://www.drugbank.com/downloads">White Papers</a></div></li><li class="nav-item dropdown"><a class="nav-link dropdown-toggle" data-toggle="dropdown" href="#">About</a><div class="dropdown-menu right-menu"><div class="col-menu"><div class="menu-col"><div class="link-header dropdown-item"><a target="_blank" href="https://dev.drugbank.com/guides/index"><div class=" drugbank-icon icon-help_center"><svg class="icon" role="img" title="help_center"> <use xlink:href="/assets/plus/icons-cd39e90ea1c71389b36ffc9fc3f485bf2c6ab875ef9ea285614fcbd70cacf943.svg#help_center"> </use></svg></div> Help Center</a></div><a class="dropdown-item" target="_blank" href="https://dev.drugbank.com/guides/drugbank/citing"><div class="icon-circle drugbank-icon icon-citing"><svg class="icon" role="img" title="citing">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#citing"></use>
</svg>
</div> Citing DrugBank</a><a class="dropdown-item" target="_blank" href="https://dev.drugbank.com/guides/faqs"><div class="icon-circle drugbank-icon icon-faq"><svg class="icon" role="img" title="faq">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#faq"></use>
</svg>
</div> DrugBank Online FAQs</a><a class="dropdown-item" target="_blank" href="https://dev.drugbank.com/guides/drugbank/searching"><div class="icon-circle drugbank-icon icon-search"><svg class="icon" role="img" title="search">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#search"></use>
</svg>
</div> Searching DrugBank</a><a class="dropdown-item" target="_blank" href="https://dev.drugbank.com/guides/drugbank/other_databases"><div class="icon-circle drugbank-icon icon-database"><svg class="icon" role="img" title="database">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#database"></use>
</svg>
</div> Other Databases</a><a class="dropdown-item" target="_blank" href="https://dev.drugbank.com/guides/fields/drugs"><div class="icon-circle drugbank-icon icon-data-sources"><svg class="icon" role="img" title="data-sources">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#data-sources"></use>
</svg>
</div> Data Sources</a></div><div class="menu-col"><div class="link-header dropdown-item"><div class=" drugbank-icon icon-quick_link"><svg class="icon" role="img" title="quick_link"> <use xlink:href="/assets/plus/icons-cd39e90ea1c71389b36ffc9fc3f485bf2c6ab875ef9ea285614fcbd70cacf943.svg#quick_link"> </use></svg></div> About</div><a class="dropdown-item" href="/about"><div class="icon-circle drugbank-icon icon-drugbank"><svg class="icon" role="img" title="drugbank">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#drugbank"></use>
</svg>
</div> About DrugBank Online</a><a class="dropdown-item" target="_blank" href="https://dev.drugbank.com/publications"><div class="icon-circle drugbank-icon icon-search"><svg class="icon" role="img" title="search">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#search"></use>
</svg>
</div> DrugBank in Research</a><a class="dropdown-item" href="/stats"><div class="icon-circle drugbank-icon icon-statistics"><svg class="icon" role="img" title="statistics">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#statistics"></use>
</svg>
</div> Statistics</a><a class="dropdown-item" target="_blank" rel="noopener" href="https://blog.drugbank.com/"><div class="icon-circle drugbank-icon icon-news"><svg class="icon" role="img" title="news">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#news"></use>
</svg>
</div> Blog</a><a target="_blank" rel="noopener" class="dropdown-item" href="http://www.wishartlab.com"><div class="icon-circle drugbank-icon icon-wishart"><svg class="icon" role="img" title="wishart">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#wishart"></use>
</svg>
</div> Wishart Research Group</a><a class="dropdown-item" href="/contact"><div class="small-icon icon-circle drugbank-icon icon-paper-plane"><svg class="icon" role="img" title="paper-plane">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#paper-plane"></use>
</svg>
</div> Contact Us</a></div></div></div></li></ul></div></nav><nav class="navbar fixed-top navbar-expand search-bar justify-content-center justify-content-sm-end d-flex"><div class="form-container"><form class="form-inline" action="/unearth/q" accept-charset="UTF-8" method="get"><input name="utf8" type="hidden" value="✓"><div class="search-group d-none d-sm-block" style="margin-right: 0.5rem;"><select name="searcher" id="searcher" class="form-control input-md"><option value="drugs">Drugs</option>
<option value="bio_entities">Targets</option>
<option value="pathways">Pathways</option>
<option value="indications">Indications</option></select> <div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> </div><div class="search-group"><input type="text" name="query" id="query" class="search-query"> <div class="drugbank-icon icon-search"><svg class="icon" role="img" title="search">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#search"></use>
</svg>
</div> </div></form></div><div class="mini-banner banner-holder"><a target="_blank" href="https://blog.drugbank.com/trends-insights-research-spotlight-2021/"><div class="banner-text"><span class="mr-3">Discover published papers by academic researchers that use DrugBank data.</span><span class="banner-link"><span>Read Blog!</span><div class="icon-circle drugbank-icon icon-arrow-right"><svg class="icon" role="img" title="arrow-right">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-right"></use>
</svg>
</div></span></div></a><div class="close-banner"><div class="drugbank-icon icon-cross"><svg class="icon" role="img" title="cross">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#cross"></use>
</svg>
</div></div></div></nav></header><main role="main"><div class="content-container"><div class="content-header d-sm-flex align-items-center"><h1 class="align-self-center mr-auto">Pharmaco-metabolomics<small>Metabolite changes due to the metabolism of pharmaceutical compounds</small></h1><div class="page-actions ml-auto justify-content-sm-end mt-2 mt-sm-0"><a class="btn btn-sm btn-blue ml-sm-3 mr-2 mr-sm-0 mt-1 mb-1" href="/pharmaco/genomics">Pharmaco-genomics</a><a class="btn btn-sm btn-blue ml-sm-3 mr-2 mr-sm-0 mt-1 mb-1 disabled" href="/pharmaco/metabolomics">Pharmaco-metabolomics</a><a class="btn btn-sm btn-blue ml-sm-3 mr-2 mr-sm-0 mt-1 mb-1" href="/pharmaco/transcriptomics">Pharmaco-transcriptomics</a><a class="btn btn-sm btn-blue ml-sm-3 mr-2 mr-sm-0 mt-1 mb-1" href="/pharmaco/proteomics">Pharmaco-proteomics</a><a data-no-turbolink="true" class="btn btn-sm btn-blue ml-sm-3 mr-2 mr-sm-0 mt-1 mb-1" href="/pharmaco/search">Search</a></div></div><form class="metabolite_regulation_search" id="metabolite_regulation_search" action="/pharmaco/metabolomics" accept-charset="UTF-8" method="get"><input name="utf8" type="hidden" value="✓"><div class="container-fluid"><div class="filter-bar row justify-content-start d-flex flex-wrap flex-column flex-sm-row"><div class="advanced-toggle d-flex d-sm-none justify-content-between align-items-center"><h3>Advanced Filter</h3><div class="toggle"><div class="drugbank-icon icon-add"><svg class="icon" role="img" title="add">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#add"></use>
</svg>
</div><div class="drugbank-icon icon-subtract"><svg class="icon" role="img" title="subtract">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#subtract"></use>
</svg>
</div></div></div><div class="advanced-selector justify-content-start d-sm-flex flex-wrap flex-column flex-sm-row"><div class="group-selector d-sm-block"><h3>Filter by Group</h3><input value="or" type="hidden" name="q[g[0]][m]" id="q_g_0__m"><div class="form-check"><label class="button-control button-check-box" for="approved"><input name="q[g[0]][drug_approved_true]" type="hidden" value="all"><input class="button-control-input" id="approved" type="checkbox" value="1" name="q[g[0]][drug_approved_true]"><span class="button-control-indicator btn btn-sm"><span class="button-control-description">Approved</span></span></label></div><div class="form-check"><label class="button-control button-check-box" for="nutraceutical"><input name="q[g[0]][drug_nutraceutical_true]" type="hidden" value="all"><input class="button-control-input" id="nutraceutical" type="checkbox" value="1" name="q[g[0]][drug_nutraceutical_true]"><span class="button-control-indicator btn btn-sm"><span class="button-control-description">Nutraceutical</span></span></label></div><div class="form-check"><label class="button-control button-check-box" for="illicit"><input name="q[g[0]][drug_illicit_true]" type="hidden" value="all"><input class="button-control-input" id="illicit" type="checkbox" value="1" name="q[g[0]][drug_illicit_true]"><span class="button-control-indicator btn btn-sm"><span class="button-control-description">Illicit</span></span></label></div><div class="form-check"><label class="button-control button-check-box" for="investigational"><input name="q[g[0]][drug_investigational_true]" type="hidden" value="all"><input class="button-control-input" id="investigational" type="checkbox" value="1" name="q[g[0]][drug_investigational_true]"><span class="button-control-indicator btn btn-sm"><span class="button-control-description">Investigational</span></span></label></div><div class="form-check"><label class="button-control button-check-box" for="withdrawn"><input name="q[g[0]][drug_withdrawn_true]" type="hidden" value="all"><input class="button-control-input" id="withdrawn" type="checkbox" value="1" name="q[g[0]][drug_withdrawn_true]"><span class="button-control-indicator btn btn-sm"><span class="button-control-description">Withdrawn</span></span></label></div><div class="form-check"><label class="button-control button-check-box" for="experimental"><input name="q[g[0]][drug_experimental_true]" type="hidden" value="all"><input class="button-control-input" id="experimental" type="checkbox" value="1" name="q[g[0]][drug_experimental_true]"><span class="button-control-indicator btn btn-sm"><span class="button-control-description">Experimental</span></span></label></div></div><div class="availability-selector d-sm-block"><h3>Filter by Market Availability</h3><input value="or" type="hidden" name="q[g[1]][m]" id="q_g_1__m"><div class="form-check"><label class="button-control button-check-box" for="us"><input name="q[g[1]][drug_available_in_us_true]" type="hidden" value="all"><input class="button-control-input" id="us" type="checkbox" value="1" name="q[g[1]][drug_available_in_us_true]"><span class="button-control-indicator btn btn-sm"><span class="button-control-description">U.S.</span></span></label></div><div class="form-check"><label class="button-control button-check-box" for="ca"><input name="q[g[1]][drug_available_in_ca_true]" type="hidden" value="all"><input class="button-control-input" id="ca" type="checkbox" value="1" name="q[g[1]][drug_available_in_ca_true]"><span class="button-control-indicator btn btn-sm"><span class="button-control-description">Canada</span></span></label></div><div class="form-check"><label class="button-control button-check-box" for="eu"><input name="q[g[1]][drug_available_in_eu_true]" type="hidden" value="all"><input class="button-control-input" id="eu" type="checkbox" value="1" name="q[g[1]][drug_available_in_eu_true]"><span class="button-control-indicator btn btn-sm"><span class="button-control-description">E.U.</span></span></label></div></div><div class="submit-filter ml-sm-auto pb-sm-0 justify-content-end d-sm-flex pt-2 align-items-end text-center"><div class="submit-buttons mt-2"><a class="btn btn-drugbank-secondary btn-sm mr-2" href="https://go.drugbank.com/pharmaco/metabolomics">Clear</a><input type="submit" name="commit" value="Apply Filter" class="btn btn-drugbank-primary btn-sm" data-disable-with="Apply Filter"></div></div></div></div></div><div class="index-content"><div class="pagination-holder"><div class="page_info">Displaying entries <b>501 - 525</b> of <b>3084</b> in total</div><nav><ul class="pagination pagination-sm"><li class="page-item first"><a class="page-link" href="/pharmaco/metabolomics">«</a></li><li class="page-item previous"><a rel="prev" class="page-link" href="/pharmaco/metabolomics?page=20">‹</a></li><li class="page-item disabled"><a class="page-link" href="#">…</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=17">17</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=18">18</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=19">19</a></li><li class="page-item"><a rel="prev" class="page-link" href="/pharmaco/metabolomics?page=20">20</a></li><li class="page-item active"><a remote="false" class="page-link">21</a></li><li class="page-item"><a rel="next" class="page-link" href="/pharmaco/metabolomics?page=22">22</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=23">23</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=24">24</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=25">25</a></li><li class="page-item disabled"><a class="page-link" href="#">…</a></li><li class="page-item next"><a rel="next" class="page-link" href="/pharmaco/metabolomics?page=22">›</a></li><li class="page-item last"><a class="page-link" href="/pharmaco/metabolomics?page=124">»</a></li></ul></nav></div><table class="table-metabolite-regulations table table-bordered"><thead><tr><th>Drug</th><th>Drug Groups</th><th>Metabolite</th><th>Change</th><th>Description</th><th>Reference</th></tr><tr class="table-search-row"><th><input class=" form-control input-md input-tbl-search" type="text" name="q[drug_precise_names_name_cont]" id="q_drug_precise_names_name_cont"></th><th></th><th><input class=" form-control input-md input-tbl-search" type="text" name="q[metabolite_cont]" id="q_metabolite_cont"></th><th><select class=" form-control input-sm input-tbl-search select2-standard" name="q[change_eq]" id="q_change_eq"><option value=""></option>
<option value="increased">increased</option>
<option value="decreased">decreased</option></select></th><th></th><th class="table-search-submit"><div class="btn-group"><button name="button" type="submit" class="table-search-submit btn btn-sm btn-light"><div class="drugbank-icon icon-search-big"><svg class="icon" role="img" title="search-big">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#search-big"></use>
</svg>
</div></button> <a id="table-search-reset" class="btn btn-light btn-sm" href="/pharmaco/metabolomics">Clear</a></div></th></tr></thead><tbody><tr><td><a href="/drugs/DB00598">Labetalol</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB02886">6-keto-PGF1 alpha</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Labetalol <em>decreases</em> the level of <em>6-keto-PGF1 alpha</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25136" data-original-title="Roy L, Mehta J, Mehta P: Increased plasma concentrations of prostacyclin metabolite 6-keto-PGF1 alpha in essential hypertension. Influence of therapy with labetalol. Am J Cardiol. 1983 Feb;51(3):464-7.">A25136</a></li></ul></td></tr><tr><td><a href="/drugs/DB00959">Methylprednisolone</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Vet Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB00562">Creatinine</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Methylprednisolone <em>decreases</em> the level of <em>Creatinine</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25137" data-original-title="De Vecchi A, Montagnino G, Pozzi C, Tarantino A, Locatelli F, Ponticelli C: Intravenous methylprednisolone pulse therapy in essential mixed cryoglobulinemia nephropathy. Clin Nephrol. 1983 May;19(5):221-7.">A25137</a></li></ul></td></tr><tr><td><a href="/drugs/DB00368">Norepinephrine</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB00216">Norepinephrine</a></td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Norepinephrine <em>increases</em> the level of <em>Norepinephrine</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25138" data-original-title="Scriven AJ, Dollery CT, Murphy MB, Macquin I, Brown MJ: Blood pressure and plasma norepinephrine concentrations after endogenous norepinephrine release by tyramine. Clin Pharmacol Ther. 1983 Jun;33(6):710-6.">A25138</a></li></ul></td></tr><tr><td><a href="/drugs/DB08841">Tyramine</a></td><td><span class="badge badge-secondary badge-pill">Investigational</span> <span class="badge badge-secondary badge-pill">Nutraceutical</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB00216">Norepinephrine</a></td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Tyramine <em>increases</em> the level of <em>Norepinephrine</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25138" data-original-title="Scriven AJ, Dollery CT, Murphy MB, Macquin I, Brown MJ: Blood pressure and plasma norepinephrine concentrations after endogenous norepinephrine release by tyramine. Clin Pharmacol Ther. 1983 Jun;33(6):710-6.">A25138</a></li></ul></td></tr><tr><td><a href="/drugs/DB00202">Succinylcholine</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td>Catecholamine</td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Succinylcholine <em>increases</em> the level of <em>Catecholamine</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25139" data-original-title="Nigrovic V, McCullough LS, Wajskol A, Levin JA, Martin JT: Succinylcholine-induced increases in plasma catecholamine levels in humans. Anesth Analg. 1983 Jul;62(7):627-32.">A25139</a></li></ul></td></tr><tr><td><a href="/drugs/DB01233">Metoclopramide</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB00319">18-hydroxycorticosterone</a></td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Metoclopramide <em>increases</em> the level of <em>18-hydroxycorticosterone</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25140" data-original-title="Nagahama S, Fujimaki M, Kawabe H, Nakamura R, Saito I, Saruta T: Effect of metoclopramide on the secretion of aldosterone and other adrenocortical steroids. Clin Endocrinol (Oxf). 1983 Mar;18(3):287-93.">A25140</a></li></ul></td></tr><tr><td><a href="/drugs/DB00153">Ergocalciferol</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Nutraceutical</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB01315">Phosphorus</a></td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Ergocalciferol <em>increases</em> the level of <em>Phosphorus</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25141" data-original-title="Costa T, Marie PJ, Scriver CR, Cole DE, Reade TM, Nogrady B, Glorieux FH, Delvin EE: X-linked hypophosphatemia: effect of calcitriol on renal handling of phosphate, serum phosphate, and bone mineralization. J Clin Endocrinol Metab. 1981 Mar;52(3):463-72.">A25141</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td>Blood urea nitrogen</td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Bezafibrate <em>increases</em> the level of <em>Blood urea nitrogen</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25142" data-original-title="Lageder H: [Comparative double-blind investigation of bezafibrate and clofibrate in patients with primary hyperlipoproteinaemia]. Wien Klin Wochenschr. 1980 Feb 1;92(3):95-101.">A25142</a></li></ul></td></tr><tr><td><a href="/drugs/DB00636">Clofibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td>Blood urea nitrogen</td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Clofibrate <em>increases</em> the level of <em>Blood urea nitrogen</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25142" data-original-title="Lageder H: [Comparative double-blind investigation of bezafibrate and clofibrate in patients with primary hyperlipoproteinaemia]. Wien Klin Wochenschr. 1980 Feb 1;92(3):95-101.">A25142</a></li></ul></td></tr><tr><td><a href="/drugs/DB00636">Clofibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB00562">Creatinine</a></td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Clofibrate <em>increases</em> the level of <em>Creatinine</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25142" data-original-title="Lageder H: [Comparative double-blind investigation of bezafibrate and clofibrate in patients with primary hyperlipoproteinaemia]. Wien Klin Wochenschr. 1980 Feb 1;92(3):95-101.">A25142</a></li></ul></td></tr><tr><td><a href="/drugs/DB00384">Triamterene</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td>Blood urea nitrogen</td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Triamterene <em>increases</em> the level of <em>Blood urea nitrogen</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25143" data-original-title="DeCarvalho JG, Emery AC Jr, Frohlich ED: Spironolactone and triamterene in volume-dependent essential hypertension. Clin Pharmacol Ther. 1980 Jan;27(1):53-6.">A25143</a></li></ul></td></tr><tr><td><a href="/drugs/DB00421">Spironolactone</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td>Blood urea nitrogen</td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Spironolactone <em>increases</em> the level of <em>Blood urea nitrogen</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25143" data-original-title="DeCarvalho JG, Emery AC Jr, Frohlich ED: Spironolactone and triamterene in volume-dependent essential hypertension. Clin Pharmacol Ther. 1980 Jan;27(1):53-6.">A25143</a></li></ul></td></tr><tr><td><a href="/drugs/DB00421">Spironolactone</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB00547">Magnesium</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Spironolactone <em>decreases</em> the level of <em>Magnesium</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25144" data-original-title="Schersten B, Thulin T, Kuylenstierna J, Engstrom M, Karlberg BE, Tolagen K, Nordlander S, Nilsson G: Clinical and biochemical effects of spironolactone administered once daily in primary hypertension. Multicenter Sweden study. Hypertension. 1980 Sep-Oct;2(5):672-9.">A25144</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td>Cholesterol ester linoleate</td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Bezafibrate <em>decreases</em> the level of <em>Cholesterol ester linoleate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB00885">Cholesterol ester palmitate</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Bezafibrate <em>decreases</em> the level of <em>Cholesterol ester palmitate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td>Triglyceride linoleate</td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Bezafibrate <em>decreases</em> the level of <em>Triglyceride linoleate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB42061">Triglyceride myristate</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Bezafibrate <em>decreases</em> the level of <em>Triglyceride myristate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td>Triglyceride stearate</td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Bezafibrate <em>decreases</em> the level of <em>Triglyceride stearate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td>Phospholipid linoleate</td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Bezafibrate <em>decreases</em> the level of <em>Phospholipid linoleate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB00658">Cholesterol ester palmitoleate</a></td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Bezafibrate <em>increases</em> the level of <em>Cholesterol ester palmitoleate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB00918">Cholesterol ester oleate</a></td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Bezafibrate <em>increases</em> the level of <em>Cholesterol ester oleate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td>Triglyceride arachidonate</td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Bezafibrate <em>increases</em> the level of <em>Triglyceride arachidonate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB31125">Triglyceride palmitate</a></td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Bezafibrate <em>increases</em> the level of <em>Triglyceride palmitate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td>Triglyceride plamitoeic acid</td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Bezafibrate <em>increases</em> the level of <em>Triglyceride plamitoeic acid</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr><tr><td><a href="/drugs/DB01393">Bezafibrate</a></td><td><span class="badge badge-secondary badge-pill">Approved</span> <span class="badge badge-secondary badge-pill">Investigational</span></td><td>Phospholipid palmitoleate</td><td><span class="text-success"><div class="drugbank-icon icon-arrow-up"><svg class="icon" role="img" title="arrow-up">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-up"></use>
</svg>
</div> increased</span></td><td>Bezafibrate <em>increases</em> the level of <em>Phospholipid palmitoleate</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25145" data-original-title="Vessby B, Lithell H, Hellsing K, Ostlund-Lindqvist AM, Gustafsson IB, Boberg J, Ledermann H: Effects of bezafibrate on the serum lipoprotein lipid and apolipoprotein composition, lipoprotein triglyceride removal capacity and the fatty acid composition of the plasma lipid esters. Atherosclerosis. 1980 Oct;37(2):257-69.">A25145</a></li></ul></td></tr></tbody></table><div class="pagination-holder"><div class="page_info">Displaying entries <b>501 - 525</b> of <b>3084</b> in total</div><nav><ul class="pagination pagination-sm"><li class="page-item first"><a class="page-link" href="/pharmaco/metabolomics">«</a></li><li class="page-item previous"><a rel="prev" class="page-link" href="/pharmaco/metabolomics?page=20">‹</a></li><li class="page-item disabled"><a class="page-link" href="#">…</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=17">17</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=18">18</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=19">19</a></li><li class="page-item"><a rel="prev" class="page-link" href="/pharmaco/metabolomics?page=20">20</a></li><li class="page-item active"><a remote="false" class="page-link">21</a></li><li class="page-item"><a rel="next" class="page-link" href="/pharmaco/metabolomics?page=22">22</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=23">23</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=24">24</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=25">25</a></li><li class="page-item disabled"><a class="page-link" href="#">…</a></li><li class="page-item next"><a rel="next" class="page-link" href="/pharmaco/metabolomics?page=22">›</a></li><li class="page-item last"><a class="page-link" href="/pharmaco/metabolomics?page=124">»</a></li></ul></nav></div></div></form></div></main><footer><div class="row p-3 p-sm-4 m-0"><div class="col-md-5 footer-content"><div class="footer-item footer-commercial"><img style="width: 130px; height: 100px;" src="/assets/plus/Data_Pink-68da9b7525141f098e2e0ebcbd888ce950fe6032fd0da3a227c22117cedd7062.png" alt="Data pink"><h2>Interested in using DrugBank in a <strong>commercial product</strong> or <strong>application?</strong></h2><a class="btn btn-pink-filled" target="_blank" href="https://www.drugbank.com/">Visit DrugBank.com <div class=" drugbank-icon icon-see_more"><svg class="icon" role="img" title="see_more"> <use xlink:href="/assets/plus/icons-cd39e90ea1c71389b36ffc9fc3f485bf2c6ab875ef9ea285614fcbd70cacf943.svg#see_more"> </use></svg></div></a></div><div class="footer-item footer-newsletter hidden" id="newsletter-1"><div class="newsletter-header"><img style="width: 131px; height: 100px;" src="/assets/plus/Article_Dark_Pink-17ef3dc892e28e001abbb0ae6bfc47fca8a64cd76af37ec2a80dbce89fe3bc72.png" alt="Article dark pink"><h2>Stay up-to-date with the <br><strong>latest from DrugBank!</strong></h2></div><form action="https://dev.drugbank.com/contacts" class="form" id="newsletter-form" method="post"><input class="form-control hidden" id="contact_name" name="contact[name]" type="hidden" value="New Subscriber"><input class="form-control hidden" id="contact_mailing_list" name="contact[mailing_list]" type="hidden" value="yes"><input class="form-control hidden" id="data_type" name="data_type" type="hidden" value="json"><input class="form-control hidden" id="contact_address" name="contact[address]" type="hidden"><input class="form-control hidden" name="contact[return_url]" type="hidden" value="https://go.drugbank.com/#newsletter-3"><input class="form-control hidden" name="contact[form_url]" type="hidden" value="https://go.drugbank.com/"><input class="form-control hidden" id="referer" name="contact[referer]" type="hidden" value=""><input class="form-control hidden" id="type" name="contact[type]" type="hidden" value="newsletter"><input class="form-control hidden" id="ga_client_id" name="contact[ga_client_id]" type="hidden" value="1407225613.1636197853"><div class="input-group"><input class="form-control" id="contact_email" name="contact[email]" placeholder="Enter your email" required="" type="text"><span class="input-group-btn"><button class="btn btn-pink-filled" id="subscribe" type="submit">Subscribe</button></span></div><div class="help-block with-errors"></div></form></div><div class="footer-item footer-newsletter hidden" id="newsletter-3"><div class="newsletter-header"><img style="width: 131px; height: 100px;" src="/assets/plus/Article_Dark_Pink-17ef3dc892e28e001abbb0ae6bfc47fca8a64cd76af37ec2a80dbce89fe3bc72.png" alt="Article dark pink"><h2><strong>Thank you</strong> <br>for subscribing!</h2></div></div></div><div class="col-md-7 footer-links"><div class="container"><div class="row footer-row"><div class="col-sm-4 footer-col"><div class="footer-header">About</div><div class="footer-list"><ul class="list-unstyled"><li><a href="/about">About DrugBank Online</a></li><li><a target="_blank" href="https://blog.drugbank.com/">Blog</a></li><li><a target="_blank" href="http://www.wishartlab.com">Wishart Research Group</a></li><li><a href="https://www.drugbank.com/about/careers">Careers</a></li><li><a href="/legal/terms_of_use">Terms of Use</a></li><li><a href="/legal/privacy_policy">Privacy Policy</a></li></ul></div></div><div class="col-sm-4 footer-col"><div class="footer-header">Support</div><div class="footer-list"><ul class="list-unstyled"><li><a target="_blank" href="https://dev.drugbank.com/guides/index">Help Center</a></li><li><a target="_blank" href="https://dev.drugbank.com/guides/faqs">DrugBank Online FAQs</a></li><li><a href="/contact">Contact Support</a></li></ul></div></div><div class="col-sm-4 footer-col"><div class="footer-header"><a href="https://www.drugbank.com/">Commercial Data</a></div><div class="footer-list"><ul class="list-unstyled"><li><a target="_blank" href="https://www.drugbank.com/clinical">Clinical Drug Data</a></li><li><a target="_blank" href="https://www.drugbank.com/scientific">Scientific Drug Data</a></li><li><a target="_blank" href="https://www.drugbank.com/contact/sales?ref=go.drugbank.com%2Fpharmaco%2Fmetabolomics">Contact Sales</a></li></ul></div></div></div><div class="row footer-row"><div class="col-sm-12"><div class="social-media"><a class="social-media-link" href="https://www.linkedin.com/company/drugbank/"><div class="drugbank-icon icon-linkedin"><svg class="icon" role="img" title="linkedin">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#linkedin"></use>
</svg>
</div></a><a class="social-media-link" href="https://twitter.com/DrugBankDB"><div class="drugbank-icon icon-twitter"><svg class="icon" role="img" title="twitter">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#twitter"></use>
</svg>
</div></a><a class="social-media-link" href="https://www.facebook.com/DrugBankDatabase"><div class="drugbank-icon icon-facebook"><svg class="icon" role="img" title="facebook">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#facebook"></use>
</svg>
</div></a></div><h6>Website design by Educe Design & Innovation Inc.</h6></div></div></div></div></div></footer><script defer="" src="https://static.cloudflareinsights.com/beacon.min.js" data-cf-beacon="{"rayId":"6a9df9c40fb4623e","token":"e28ec36f07f74c1ca13c169ca4430981","version":"2021.10.0","si":100}"></script>
<script src="/assets/analytics-1b5960c76af2e5f1a83c45e21ee367baf13121e0a2d42380a71abadf0edaa402.js" media="all" data-turbolinks-track="true"></script><script type="text/javascript" id="hs-script-loader" async="" defer="" src="//js.hs-scripts.com/2224137.js"></script><iframe src="https://bid.g.doubleclick.net/xbbe/pixel?d=KAE" style="display: none;"></iframe></body></html>