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</div></div></div></nav></header><main role="main"><div class="content-container"><div class="content-header d-sm-flex align-items-center"><h1 class="align-self-center mr-auto">Pharmaco-metabolomics<small>Metabolite changes due to the metabolism of pharmaceutical compounds</small></h1><div class="page-actions ml-auto justify-content-sm-end mt-2 mt-sm-0"><a class="btn btn-sm btn-blue ml-sm-3 mr-2 mr-sm-0 mt-1 mb-1" href="/pharmaco/genomics">Pharmaco-genomics</a><a class="btn btn-sm btn-blue ml-sm-3 mr-2 mr-sm-0 mt-1 mb-1 disabled" href="/pharmaco/metabolomics">Pharmaco-metabolomics</a><a class="btn btn-sm btn-blue ml-sm-3 mr-2 mr-sm-0 mt-1 mb-1" href="/pharmaco/transcriptomics">Pharmaco-transcriptomics</a><a class="btn btn-sm btn-blue ml-sm-3 mr-2 mr-sm-0 mt-1 mb-1" href="/pharmaco/proteomics">Pharmaco-proteomics</a><a data-no-turbolink="true" class="btn btn-sm btn-blue ml-sm-3 mr-2 mr-sm-0 mt-1 mb-1" href="/pharmaco/search">Search</a></div></div><form class="metabolite_regulation_search" id="metabolite_regulation_search" action="/pharmaco/metabolomics" accept-charset="UTF-8" method="get"><input name="utf8" type="hidden" value="✓"><div class="container-fluid"><div class="filter-bar row justify-content-start d-flex flex-wrap flex-column flex-sm-row"><div class="advanced-toggle d-flex d-sm-none justify-content-between align-items-center"><h3>Advanced Filter</h3><div class="toggle"><div class="drugbank-icon icon-add"><svg class="icon" role="img" title="add">
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1875</b> of <b>3084</b> in total</div><nav><ul class="pagination pagination-sm"><li class="page-item first"><a class="page-link" href="/pharmaco/metabolomics">«</a></li><li class="page-item previous"><a rel="prev" class="page-link" href="/pharmaco/metabolomics?page=74">‹</a></li><li class="page-item disabled"><a class="page-link" href="#">…</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=71">71</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=72">72</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=73">73</a></li><li class="page-item"><a rel="prev" class="page-link" href="/pharmaco/metabolomics?page=74">74</a></li><li class="page-item active"><a remote="false" class="page-link">75</a></li><li class="page-item"><a rel="next" class="page-link" href="/pharmaco/metabolomics?page=76">76</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=77">77</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=78">78</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=79">79</a></li><li class="page-item disabled"><a class="page-link" href="#">…</a></li><li class="page-item next"><a rel="next" class="page-link" href="/pharmaco/metabolomics?page=76">›</a></li><li class="page-item last"><a class="page-link" href="/pharmaco/metabolomics?page=124">»</a></li></ul></nav></div><table class="table-metabolite-regulations table table-bordered"><thead><tr><th>Drug</th><th>Drug Groups</th><th>Metabolite</th><th>Change</th><th>Description</th><th>Reference</th></tr><tr class="table-search-row"><th><input class=" form-control input-md input-tbl-search" type="text" name="q[drug_precise_names_name_cont]" id="q_drug_precise_names_name_cont"></th><th></th><th><input class=" form-control input-md input-tbl-search" type="text" name="q[metabolite_cont]" id="q_metabolite_cont"></th><th><select class=" form-control input-sm input-tbl-search select2-standard" name="q[change_eq]" id="q_change_eq"><option value=""></option>
<option value="increased">increased</option>
<option value="decreased">decreased</option></select></th><th></th><th class="table-search-submit"><div class="btn-group"><button name="button" type="submit" class="table-search-submit btn btn-sm btn-light"><div class="drugbank-icon icon-search-big"><svg class="icon" role="img" title="search-big">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#search-big"></use>
</svg>
</div></button> <a id="table-search-reset" class="btn btn-light btn-sm" href="/pharmaco/metabolomics">Clear</a></div></th></tr></thead><tbody><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB10370">Cholesterol ester 18:3n3</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>Cholesterol ester 18:3n3</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB06731">Cholesterol ester 20:5n3</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>Cholesterol ester 20:5n3</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB10375">Cholesterol ester 22:5n3</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>Cholesterol ester 22:5n3</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB06733">Cholesterol ester 22:6n3</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>Cholesterol ester 22:6n3</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0056177">Diacylglycerol 18:1n7</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>Diacylglycerol 18:1n7</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0056197">Diacylglycerol 18:1n9</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>Diacylglycerol 18:1n9</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0056282">Diacylglycerol 18:2n6</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>Diacylglycerol 18:2n6</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB10382">LysoPC 16:0</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>LysoPC 16:0</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB10384">LysoPC 18:0</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>LysoPC 18:0</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB10396">LysoPC 20:4n3</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>LysoPC 20:4n3</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0007866">PC 14:0</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 14:0</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0007934">PC 15:0</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 15:0</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0000564">PC 16:0</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 16:0</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008036">PC 18:0</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 18:0</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008002">PC 16:1n7</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 16:1n7</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008070">PC 18:1n7</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 18:1n7</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0000593">PC 18:1n9</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 18:1n9</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008376">PC 20:3n9</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 20:3n9</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008138">PC 18:2n6</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 18:2n6</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008172">PC 18:3n6</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 18:3n6</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008342">PC 20:2n6</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 20:2n6</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008409">PC 20:3n6</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 20:3n6</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008646">PC 22:4n6</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 22:4n6</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008680">PC 22:5n6</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 22:5n6</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr><tr><td><a href="/drugs/DB00641">Simvastatin</a></td><td><span class="badge badge-secondary badge-pill">Approved</span></td><td><a target="_blank" rel="noopener" href="http://www.hmdb.ca/metabolites/HMDB0008206">PC 18:3n3</a></td><td><span class="text-danger"><div class="drugbank-icon icon-arrow-down"><svg class="icon" role="img" title="arrow-down">
<use xlink:href="/assets/icons-b5e582577bf5da72d1df8a7d1b81629eea1cc7deaae8c957adf46f1fbe736051.svg#arrow-down"></use>
</svg>
</div> decreased</span></td><td>Simvastatin <em>decreases</em> the level of <em>PC 18:3n3</em> in the blood</td><td><ul class="list-unstyled table-list"><li><a target="_blank" title="" class="tips" href="/articles/A25760" data-original-title="Kaddurah-Daouk R, Weinshilboum R: Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. Clin Pharmacol Ther. 2015 Jul;98(1):71-5. doi: 10.1002/cpt.134. Epub 2015 Jun 4.">A25760</a></li></ul></td></tr></tbody></table><div class="pagination-holder"><div class="page_info">Displaying entries <b>1851 - 1875</b> of <b>3084</b> in total</div><nav><ul class="pagination pagination-sm"><li class="page-item first"><a class="page-link" href="/pharmaco/metabolomics">«</a></li><li class="page-item previous"><a rel="prev" class="page-link" href="/pharmaco/metabolomics?page=74">‹</a></li><li class="page-item disabled"><a class="page-link" href="#">…</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=71">71</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=72">72</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=73">73</a></li><li class="page-item"><a rel="prev" class="page-link" href="/pharmaco/metabolomics?page=74">74</a></li><li class="page-item active"><a remote="false" class="page-link">75</a></li><li class="page-item"><a rel="next" class="page-link" href="/pharmaco/metabolomics?page=76">76</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=77">77</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=78">78</a></li><li class="page-item"><a class="page-link" href="/pharmaco/metabolomics?page=79">79</a></li><li class="page-item disabled"><a class="page-link" href="#">…</a></li><li class="page-item next"><a rel="next" class="page-link" href="/pharmaco/metabolomics?page=76">›</a></li><li class="page-item last"><a class="page-link" href="/pharmaco/metabolomics?page=124">»</a></li></ul></nav></div></div></form></div></main><footer><div class="row p-3 p-sm-4 m-0"><div class="col-md-5 footer-content"><div class="footer-item footer-commercial hidden"><img style="width: 130px; 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