diff --git a/src/ontology/mp-edit.owl b/src/ontology/mp-edit.owl index c20391aa..22e8d0eb 100644 --- a/src/ontology/mp-edit.owl +++ b/src/ontology/mp-edit.owl @@ -14436,6 +14436,12 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -17119,12 +17125,12 @@ SubClassOf( (heart valve hypoplasia) -AnnotationAssertion(Annotation( "PMID:9362461") "decrease in the number of normal cells in normal arrangement in the heart valves, typically resulting in decreased size") +AnnotationAssertion(Annotation( "PMID:9362461") "decrease in the number of normal cells in normal arrangement in any of the heart valves, typically resulting in decreased size") AnnotationAssertion( "hypoplastic heart valves") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "MP:0000287") AnnotationAssertion(rdfs:label "heart valve hypoplasia") -EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) +EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) # Class: (abnormal pericardium morphology) @@ -52414,13 +52420,13 @@ SubClassOf( (heart valve hyperplasia) -AnnotationAssertion(Annotation( "MGI:anna") "increase in the number of normal cells in normal arrangement in the heart valves, typically resulting in increased size") +AnnotationAssertion(Annotation( "MGI:anna") "increase in the number of normal cells in normal arrangement in any of the heart valves, typically resulting in increased size") AnnotationAssertion( "hyperplastic cardiac valves") AnnotationAssertion( "hyperplastic heart valves") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "MP:0003958") AnnotationAssertion(rdfs:label "heart valve hyperplasia") -EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) +EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) # Class: (abnormal lean body mass) @@ -70971,9 +70977,14 @@ SubClassOf( (tricuspid valve regurgitation) AnnotationAssertion(Annotation( "MGI:smb") Annotation( "RGD:cur") "the backward reflux of blood through the tricuspid valve, due to insufficiency caused by disease, aging or congenital malformation") +AnnotationAssertion( ) AnnotationAssertion( "Fyler:1161") AnnotationAssertion( "tricuspid regurgitation") AnnotationAssertion( "tricuspid valve insufficiency") +AnnotationAssertion( "right AV valve insufficiency") +AnnotationAssertion( "right AV valve regurgitation") +AnnotationAssertion( "right atrioventricular valve insufficiency") +AnnotationAssertion( "right atrioventricular valve regurgitation") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "MP:0006044") AnnotationAssertion( ) @@ -70984,10 +70995,15 @@ SubClassOf( (mitral valve regurgitation) AnnotationAssertion(Annotation( "MGI:smb") Annotation( "RGD:cur") "the backward reflux of blood through the mitral valve, due to insufficiency caused by disease, aging or congenital malformation") +AnnotationAssertion( ) AnnotationAssertion( "Fyler:1151") AnnotationAssertion( "bicuspid valve insufficiency") AnnotationAssertion( "mitral regurgitation") AnnotationAssertion( "mitral valve insufficiency") +AnnotationAssertion( "left AV valve insufficiency") +AnnotationAssertion( "left AV valve regurgitation") +AnnotationAssertion( "left atrioventricular valve insufficiency") +AnnotationAssertion( "left atrioventricular valve regurgitation") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "MP:0006045") AnnotationAssertion( ) @@ -71000,6 +71016,8 @@ SubClassOf( "MGI:smb") Annotation( "RGD:cur") "the backward reflux of blood through the atrioventricular valve, due to insufficiency caused by disease, aging or congenital malformation") AnnotationAssertion( "AVSD AV valvar regurgitation") AnnotationAssertion( "atrioventricular valve insufficiency") +AnnotationAssertion( "AV valve insufficiency") +AnnotationAssertion( "AV valve regurgitation") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "MP:0006046") AnnotationAssertion( ) @@ -71816,6 +71834,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "mitral valve stenosis") SubClassOf( ) +SubClassOf( ) # Class: (tricuspid valve atresia) @@ -71833,7 +71852,7 @@ SubClassOf( (tricuspid valve stenosis) -AnnotationAssertion(Annotation( "MGI:smb") Annotation( "NCBI:matt") "abnormal narrowing of the tricuspid valve") +AnnotationAssertion(Annotation( "MGI:smb") Annotation( "NCBI:matt") "abnormal narrowing or constriction of the tricuspid valve") AnnotationAssertion( "right AV valve stenosis") AnnotationAssertion( "right atrioventricular valve stenosis") AnnotationAssertion( "tricuspid stenosis") @@ -71842,6 +71861,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tricuspid valve stenosis") SubClassOf( ) +SubClassOf( ) # Class: (tricuspid valve prolapse) @@ -107658,6 +107678,7 @@ AnnotationAssertion( "enlarged mitral valve") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) +SubClassOf( ) # Class: (patent mitral valve) @@ -107694,6 +107715,7 @@ AnnotationAssertion( "thick mitral valve") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) +SubClassOf( ) # Class: (abnormal tricuspid valve annulus morphology) @@ -107806,6 +107828,7 @@ AnnotationAssertion( "enlarged tricuspid valve") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) +SubClassOf( ) # Class: (patent tricuspid valve) @@ -107838,6 +107861,7 @@ AnnotationAssertion( "thick tricuspid valve") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) +SubClassOf( ) # Class: (abnormal cardiac muscle tissue morphology) @@ -122944,8 +122968,8 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tricuspid valve hypoplasia") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) -SubClassOf( ) SubClassOf( ) +SubClassOf( ) # Class: (atrium cyst) @@ -186191,6 +186215,7 @@ AnnotationAssertion( "small mitral valve") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) +SubClassOf( ) # Class: (mitral valve hypoplasia) @@ -186210,8 +186235,8 @@ AnnotationAssertion( "MP:0031523") AnnotationAssertion(rdfs:label "mitral valve hypoplasia") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) -SubClassOf( ) SubClassOf( ) +SubClassOf( ) # Class: (mitral valve hyperplasia) @@ -186231,8 +186256,8 @@ AnnotationAssertion( "MP:0031524") AnnotationAssertion(rdfs:label "mitral valve hyperplasia") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) -SubClassOf( ) SubClassOf( ) +SubClassOf( ) # Class: (thin left ventricle myocardium compact layer) @@ -186718,6 +186743,7 @@ AnnotationAssertion( "small tricuspid valve") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) +SubClassOf( ) # Class: (tricuspid valve hyperplasia) @@ -186733,8 +186759,8 @@ AnnotationAssertion( "MP:0031558") AnnotationAssertion(rdfs:label "tricuspid valve hyperplasia") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) -SubClassOf( ) SubClassOf( ) +SubClassOf( ) # Class: (tricuspid valve hypertrophy) @@ -186916,6 +186942,101 @@ AnnotationAssertion(rdfs:label "aort EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) +# Class: (enlarged atrioventricular valve) + +AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6490-7723") "an increase in the total area occupied by either one or both of the atrioventricular valves") +AnnotationAssertion( "2024-01-09T13:15:06Z"^^xsd:dateTime) +AnnotationAssertion( ) +AnnotationAssertion( "enlarged AV valve") +AnnotationAssertion( "enlarged atrioventricular valves") +AnnotationAssertion( "increased AV valve size") +AnnotationAssertion( "increased atrioventricular valve size") +AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "MP:0031570") +AnnotationAssertion(rdfs:label "enlarged atrioventricular valve") +EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) +SubClassOf( ) + +# Class: (atrioventricular valve hyperplasia) + +AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6490-7723") "increase in the number of normal cells in normal arrangement in either one or both of the atrioventricular valves, typically resulting in increased size") +AnnotationAssertion( "2024-01-09T13:21:52Z"^^xsd:dateTime) +AnnotationAssertion( ) +AnnotationAssertion( "AV valve hyperplasia") +AnnotationAssertion( "hyperplastic AV valve") +AnnotationAssertion( "hyperplastic AV valves") +AnnotationAssertion( "hyperplastic atrioventricular valve") +AnnotationAssertion( "hyperplastic atrioventricular valves") +AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "MP:0031571") +AnnotationAssertion(rdfs:label "atrioventricular valve hyperplasia") +EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) +SubClassOf( ) +SubClassOf( ) + +# Class: (small atrioventricular valve) + +AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6490-7723") "a decrease in the total area occupied by either one or both of the atrioventricular valves") +AnnotationAssertion( "2024-01-09T13:37:57Z"^^xsd:dateTime) +AnnotationAssertion( ) +AnnotationAssertion( "decreased AV valve size") +AnnotationAssertion( "decreased atrioventricular valve size") +AnnotationAssertion( "reduced AV valve size") +AnnotationAssertion( "reduced atrioventricular valve size") +AnnotationAssertion( "small AV valve") +AnnotationAssertion( "small atrioventricular valves") +AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "MP:0031572") +AnnotationAssertion(rdfs:label "small atrioventricular valve") +EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) +SubClassOf( ) + +# Class: (atrioventricular valve hypoplasia) + +AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6490-7723") "decrease in the number of normal cells in normal arrangement in either one or both of the atrioventricular valves, typically resulting in decreased size") +AnnotationAssertion( "2024-01-09T13:46:04Z"^^xsd:dateTime) +AnnotationAssertion( ) +AnnotationAssertion( "AV valve hypoplasia") +AnnotationAssertion( "hypoplastic AV valve") +AnnotationAssertion( "hypoplastic AV valves") +AnnotationAssertion( "hypoplastic atrioventricular valve") +AnnotationAssertion( "hypoplastic atrioventricular valves") +AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "MP:0031573") +AnnotationAssertion(rdfs:label "atrioventricular valve hypoplasia") +EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) +SubClassOf( ) +SubClassOf( ) + +# Class: (thick atrioventricular valve) + +AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6490-7723") "an increase in the ratio of an atrioventricular valve wall thickness to the atrioventricular septum thickness") +AnnotationAssertion( "2024-01-09T13:55:36Z"^^xsd:dateTime) +AnnotationAssertion( ) +AnnotationAssertion( "thick AV valve") +AnnotationAssertion( "thick atrioventricular valves") +AnnotationAssertion( "thickened atrioventricular valve") +AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "MP:0031574") +AnnotationAssertion(rdfs:label "thick atrioventricular valve") +EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) +SubClassOf( ) + +# Class: (atrioventricular valve stenosis) + +AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6490-7723") "abnormal narrowing or constriction of either one or both of the atrioventricular valves") +AnnotationAssertion( "2024-01-09T14:05:14Z"^^xsd:dateTime) +AnnotationAssertion( ) +AnnotationAssertion( "AV valve stenosis") +AnnotationAssertion( "stenotic AV valve") +AnnotationAssertion( "stenotic atrioventricular valve") +AnnotationAssertion( "stenotic atrioventricular valves") +AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "MP:0031575") +AnnotationAssertion(rdfs:label "atrioventricular valve stenosis") +EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) +SubClassOf( ) + # Class: (abnormal gastrula morphology) AnnotationAssertion(Annotation( "http://discovery.lifemapsc.com/library/review-of-medical-embryology/chapter-18-week-3-of-development-trilaminar-germ-disk-embryo-formation-and-gastrulation") "any structural anomaly of the pear shaped trilaminar embryonic stage in which the primititve streak elongates, the epiblast cells migrate medially towards the streak, enter the primitive groove and migrate laterally to organize into the intraembryonic mesoderm (epithelio-mesenchymal transition) between the embryonic ectoderm and primitive endoderm; the notochordal process forms and extends, and the disc becomes pear shaped as the notochordal process grows")