diff --git a/src/ontology/mp-edit.owl b/src/ontology/mp-edit.owl
index e44133fe..bb897610 100644
--- a/src/ontology/mp-edit.owl
+++ b/src/ontology/mp-edit.owl
@@ -11837,6 +11837,9 @@ Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014523>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014524>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014525>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014526>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014527>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014528>))
+Declaration(Class(<http://purl.obolibrary.org/obo/MP_0014529>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0020000>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0020001>))
 Declaration(Class(<http://purl.obolibrary.org/obo/MP_0020002>))
@@ -100003,6 +100006,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0010061> "increased creatine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0010061> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16919>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0010061> <http://purl.obolibrary.org/obo/MP_0010060>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0010061> <http://purl.obolibrary.org/obo/MP_0014527>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0010062> (decreased creatine level)
 
@@ -100021,6 +100025,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0010062> "decreased creatine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0010062> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16919>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0010062> <http://purl.obolibrary.org/obo/MP_0010060>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0010062> <http://purl.obolibrary.org/obo/MP_0014528>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0010063> (abnormal circulating creatine level)
 
@@ -136063,6 +136068,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0012604> "decreased glutathione level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0012604> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16856>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0012604> <http://purl.obolibrary.org/obo/MP_0012603>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0012604> <http://purl.obolibrary.org/obo/MP_0014528>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0012605> (decreased kidney glutathione level)
 
@@ -136091,6 +136097,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0012606> "increased glutathione level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0012606> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16856>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0012606> <http://purl.obolibrary.org/obo/MP_0012603>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0012606> <http://purl.obolibrary.org/obo/MP_0014527>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0012607> (increased kidney glutathione level)
 
@@ -154546,6 +154553,40 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://pu
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014526> "enhanced pulmonary alveolar fluid clearance")
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0014526> <http://purl.obolibrary.org/obo/MP_0014524>)
 
+# Class: <http://purl.obolibrary.org/obo/MP_0014527> (increased amino acid level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/CHEBI_33709>) <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014527> "increase in the amount of a carboxylic acid containing one or more amino groups (-NH2) and a carboxyl (-COOH) group")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014527> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014527> "2024-08-07T20:53:12Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014527> "elevated amino acid level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014527> "MP:0014527")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014527> "increased amino acid level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014527> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_33709>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014527> <http://purl.obolibrary.org/obo/MP_0005332>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014528> (decreased amino acid level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <http://purl.obolibrary.org/obo/CHEBI_33709>) <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014528> "reduction in the amount of a carboxylic acid containing one or more amino groups (-NH2) and a carboxyl (-COOH) group")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014528> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014528> "2024-08-07T20:53:25Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014528> "reduced amino acid level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014528> "MP:0014528")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014528> "decreased amino acid level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014528> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_33709>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014528> <http://purl.obolibrary.org/obo/MP_0005332>)
+
+# Class: <http://purl.obolibrary.org/obo/MP_0014529> (decreased beta-alanine level)
+
+AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> "GO:0019482") <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0014529> "reduction in the amount of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine; it occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> <http://purl.obolibrary.org/obo/MP_0014529> <https://orcid.org/0000-0003-4606-0597>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> <http://purl.obolibrary.org/obo/MP_0014529> "2024-08-07T20:58:20Z"^^xsd:dateTime)
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> <http://purl.obolibrary.org/obo/MP_0014529> "reduced beta-alanine level")
+AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0014529> "MP:0014529")
+AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0014529> "decreased beta-alanine level")
+EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0014529> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16958>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014529> <http://purl.obolibrary.org/obo/MP_0014528>)
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0014529> <http://purl.obolibrary.org/obo/MP_0030729>)
+
 # Class: <http://purl.obolibrary.org/obo/MP_0020000> (abnormal response to antigen)
 
 AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#hasDbXref> <https://orcid.org/0000-0001-5208-3432>) <http://purl.obolibrary.org/obo/IAO_0000115> <http://purl.obolibrary.org/obo/MP_0020000> "anomaly in the immune response after exposure to an antigen")
@@ -157323,6 +157364,7 @@ AnnotationAssertion(Annotation(<http://www.geneontology.org/formats/oboInOwl#cre
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0020237> "MP:0020237")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0020237> "increased proline level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0020237> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_26271>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0020237> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0020237> <http://purl.obolibrary.org/obo/MP_0020236>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0020238> (decreased proline level)
@@ -157332,6 +157374,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0020238> "MP:0020238")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0020238> "decreased proline level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0020238> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_26271>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0020238> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0020238> <http://purl.obolibrary.org/obo/MP_0020236>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0020239> (abnormal skeletal muscle cell apoptosis)
@@ -176799,6 +176842,7 @@ AnnotationAssertion(<http://purl.org/dc/elements/1.1/date> <http://purl.obolibra
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0030622> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030622> "MP:0030622")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030622> "increased cysteine level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030622> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030622> <http://purl.obolibrary.org/obo/MP_0030621>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030623> (decreased cysteine level)
@@ -176810,6 +176854,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0030623> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030623> "MP:0030623")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030623> "decreased cysteine level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030623> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030623> <http://purl.obolibrary.org/obo/MP_0030621>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030624> (abnormal circulating cysteine level)
@@ -176951,6 +176996,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030635> "MP:0030635")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030635> "increased taurine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030635> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_15891>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030635> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030635> <http://purl.obolibrary.org/obo/MP_0030634>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030636> (decreased taurine level)
@@ -176963,6 +177009,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030636> "MP:0030636")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030636> "decreased taurine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030636> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_15891>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030636> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030636> <http://purl.obolibrary.org/obo/MP_0030634>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030637> (abnormal circulating taurine level)
@@ -177023,6 +177070,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030641> "MP:0030641")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030641> "increased methionine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030641> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16811>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030641> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030641> <http://purl.obolibrary.org/obo/MP_0030640>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030642> (decreased methionine level)
@@ -177035,6 +177083,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030642> "MP:0030642")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030642> "decreased methionine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030642> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16811>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030642> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030642> <http://purl.obolibrary.org/obo/MP_0030640>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030643> (abnormal circulating methionine level)
@@ -177106,6 +177155,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030647> "MP:0030647")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030647> "increased ornithine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030647> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_18257>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030647> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030647> <http://purl.obolibrary.org/obo/MP_0030646>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030648> (decreased ornithine level)
@@ -177118,6 +177168,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030648> "MP:0030648")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030648> "decreased ornithine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030648> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_18257>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030648> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030648> <http://purl.obolibrary.org/obo/MP_0030646>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030649> (abnormal circulating ornithine level)
@@ -177274,6 +177325,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030658> "MP:0030658")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030658> "increased glycine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030658> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_15428>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030658> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030658> <http://purl.obolibrary.org/obo/MP_0030657>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030659> (decreased glycine level)
@@ -177286,6 +177338,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030659> "MP:0030659")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030659> "decreased glycine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030659> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_15428>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030659> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030659> <http://purl.obolibrary.org/obo/MP_0030657>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030660> (abnormal circulating arginine level)
@@ -177357,6 +177410,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030664> "MP:0030664")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030664> "increased arginine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030664> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_29016>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030664> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030664> <http://purl.obolibrary.org/obo/MP_0030663>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030665> (decreased arginine level)
@@ -177369,6 +177423,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030665> "MP:0030665")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030665> "decreased arginine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030665> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_29016>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030665> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030665> <http://purl.obolibrary.org/obo/MP_0030663>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030666> (abnormal circulating proline level)
@@ -177563,6 +177618,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030678> "MP:0030678")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030678> "increased hydroxyproline level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030678> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_24741>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030678> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030678> <http://purl.obolibrary.org/obo/MP_0030677>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030679> (decreased hydroxyproline level)
@@ -177575,6 +177631,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030679> "MP:0030679")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030679> "decreased hydroxyproline level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030679> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_24741>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030679> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030679> <http://purl.obolibrary.org/obo/MP_0030677>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030680> (abnormal circulating hydroxyproline level)
@@ -177641,6 +177698,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030684> "MP:0030684")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030684> "increased cystathionine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030684> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_17755>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030684> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030684> <http://purl.obolibrary.org/obo/MP_0030683>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030685> (decreased cystathionine level)
@@ -177653,6 +177711,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030685> "MP:0030685")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030685> "decreased cystathionine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030685> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_17755>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030685> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030685> <http://purl.obolibrary.org/obo/MP_0030683>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030686> (abnormal circulating cystathionine level)
@@ -177738,6 +177797,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030691> "MP:0030691")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030691> "increased serine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030691> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_17822>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030691> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030691> <http://purl.obolibrary.org/obo/MP_0030690>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030692> (decreased serine level)
@@ -177750,6 +177810,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030692> "MP:0030692")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030692> "decreased serine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030692> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_17822>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030692> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030692> <http://purl.obolibrary.org/obo/MP_0030690>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030693> (abnormal circulating serine level)
@@ -177819,6 +177880,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030697> "MP:0030697")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030697> "increased phenylalanine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030697> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_28044>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030697> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030697> <http://purl.obolibrary.org/obo/MP_0030696>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030698> (decreased phenylalanine level)
@@ -177831,6 +177893,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030698> "MP:0030698")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030698> "decreased phenylalanine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030698> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_28044>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030698> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030698> <http://purl.obolibrary.org/obo/MP_0030696>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030699> (abnormal threonine level)
@@ -177853,6 +177916,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030700> "MP:0030700")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030700> "increased threonine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030700> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_26986>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030700> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030700> <http://purl.obolibrary.org/obo/MP_0030699>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030701> (decreased threonine level)
@@ -177865,6 +177929,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030701> "MP:0030701")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030701> "decreased threonine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030701> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_26986>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030701> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030701> <http://purl.obolibrary.org/obo/MP_0030699>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030702> (abnormal circulating threonine level)
@@ -177932,6 +177997,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030706> "MP:0030706")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030706> "increased glutamine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030706> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_28300>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030706> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030706> <http://purl.obolibrary.org/obo/MP_0030705>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030707> (decreased glutamine level)
@@ -177944,6 +178010,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030707> "MP:0030707")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030707> "decreased glutamine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030707> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_28300>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030707> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030707> <http://purl.obolibrary.org/obo/MP_0030705>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030708> (abnormal circulating glutamine level)
@@ -178013,6 +178080,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030712> "MP:0030712")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030712> "increased isoleucine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030712> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_24898>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030712> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030712> <http://purl.obolibrary.org/obo/MP_0030711>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030713> (decreased isoleucine level)
@@ -178025,6 +178093,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030713> "MP:0030713")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030713> "decreased isoleucine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030713> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_24898>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030713> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030713> <http://purl.obolibrary.org/obo/MP_0030711>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030714> (abnormal circulating isoleucine level)
@@ -178143,6 +178212,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030721> "MP:0030721")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030721> "increased lysine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030721> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_25094>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030721> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030721> <http://purl.obolibrary.org/obo/MP_0030720>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030722> (decreased lysine level)
@@ -178155,6 +178225,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030722> "MP:0030722")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030722> "decreased lysine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030722> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_25094>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030722> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030722> <http://purl.obolibrary.org/obo/MP_0030720>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030723> (abnormal valine level)
@@ -178177,6 +178248,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030724> "MP:0030724")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030724> "increased valine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030724> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_27266>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030724> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030724> <http://purl.obolibrary.org/obo/MP_0030723>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030725> (decreased valine level)
@@ -178189,6 +178261,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030725> "MP:0030725")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030725> "decreased valine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030725> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_27266>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030725> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030725> <http://purl.obolibrary.org/obo/MP_0030723>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030726> (abnormal circulating valine level)
@@ -178260,6 +178333,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030730> "MP:0030730")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030730> "increased beta-alanine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030730> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16958>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030730> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030730> <http://purl.obolibrary.org/obo/MP_0030729>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030731> (abnormal gamma-aminobutyric acid level)
@@ -178288,6 +178362,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030732> "MP:0030732")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030732> "increased gamma-aminobutyric acid level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030732> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16865>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030732> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030732> <http://purl.obolibrary.org/obo/MP_0030731>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030733> (decreased gamma-aminobutyric acid level)
@@ -178344,6 +178419,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030736> "MP:0030736")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030736> "increased glutamic acid level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030736> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_18237>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030736> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030736> <http://purl.obolibrary.org/obo/MP_0030735>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030737> (decreased glutamic acid level)
@@ -178358,6 +178434,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030737> "MP:0030737")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030737> "decreased glutamic acid level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030737> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_18237>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030737> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030737> <http://purl.obolibrary.org/obo/MP_0030735>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030738> (abnormal circulating glutamic acid level)
@@ -178429,6 +178506,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0030742> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030742> "MP:0030742")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030742> "increased aspartic acid level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030742> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030742> <http://purl.obolibrary.org/obo/MP_0030741>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030743> (decreased aspartic acid level)
@@ -178442,6 +178520,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasExactSynony
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespace> <http://purl.obolibrary.org/obo/MP_0030743> "MPheno.ontology")
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030743> "MP:0030743")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030743> "decreased aspartic acid level")
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030743> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030743> <http://purl.obolibrary.org/obo/MP_0030741>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030744> (abnormal circulating homocitrulline level)
@@ -178488,6 +178567,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030747> "MP:0030747")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030747> "increased leucine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030747> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_25017>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030747> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030747> <http://purl.obolibrary.org/obo/MP_0030746>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030748> (decreased leucine level)
@@ -178500,6 +178580,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0030748> "MP:0030748")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0030748> "decreased leucine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0030748> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_25017>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0030748> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0030748> <http://purl.obolibrary.org/obo/MP_0030746>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0030749> (abnormal circulating leucine level)
@@ -190620,6 +190701,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0031639> "MP:0031639")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0031639> "decreased alanine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0031639> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0001997> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16449>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0031639> <http://purl.obolibrary.org/obo/MP_0014528>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0031639> <http://purl.obolibrary.org/obo/MP_0031638>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0031640> (increased alanine level)
@@ -190634,6 +190716,7 @@ AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#hasOBONamespac
 AnnotationAssertion(<http://www.geneontology.org/formats/oboInOwl#id> <http://purl.obolibrary.org/obo/MP_0031640> "MP:0031640")
 AnnotationAssertion(rdfs:label <http://purl.obolibrary.org/obo/MP_0031640> "increased alanine level")
 EquivalentClasses(<http://purl.obolibrary.org/obo/MP_0031640> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000051> ObjectIntersectionOf(<http://purl.obolibrary.org/obo/PATO_0000470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0000052> <http://purl.obolibrary.org/obo/CHEBI_16449>) ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/RO_0002573> <http://purl.obolibrary.org/obo/PATO_0000460>))))
+SubClassOf(<http://purl.obolibrary.org/obo/MP_0031640> <http://purl.obolibrary.org/obo/MP_0014527>)
 SubClassOf(<http://purl.obolibrary.org/obo/MP_0031640> <http://purl.obolibrary.org/obo/MP_0031638>)
 
 # Class: <http://purl.obolibrary.org/obo/MP_0031641> (alaninuria)