From ea6a25710866f21e13a35789ce3a1bd844d16ece Mon Sep 17 00:00:00 2001 From: "Anna V. Anagnostopoulos" Date: Mon, 19 Feb 2024 07:32:17 -0500 Subject: [PATCH] Closes #3911 --- src/ontology/mp-edit.owl | 20 +++++++++++++++++++- 1 file changed, 19 insertions(+), 1 deletion(-) diff --git a/src/ontology/mp-edit.owl b/src/ontology/mp-edit.owl index 8687e897..f5aea064 100644 --- a/src/ontology/mp-edit.owl +++ b/src/ontology/mp-edit.owl @@ -14480,6 +14480,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -156282,6 +156283,7 @@ SubClassOf( ) Annotation( "GO:0005783") "any functional anomaly of the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells") AnnotationAssertion( "abnormal ER physiology") +AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "MP:0020352") AnnotationAssertion(rdfs:label "abnormal endoplasmic reticulum physiology") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -156291,14 +156293,17 @@ SubClassOf( ) Annotation( "PMID:21266244") "any anomaly in the accumulation of misfolded or unfolded proteins in the endoplasmic reticulum lumen; this accumulation maybe stimulated by genetic or enviromental factors") AnnotationAssertion( "abnormal ER stress") +AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "MP:0020353") AnnotationAssertion(rdfs:label "abnormal endoplasmic reticulum stress") SubClassOf( ) # Class: (increased endoplasmic reticulum stress) -AnnotationAssertion(Annotation( ) "increase in in the accumulation of misfolded or unfolded proteins in the endoplasmic reticulum lumen; this accumulation may be stimulated by genetic or enviromental factors") +AnnotationAssertion(Annotation( ) "increase in the accumulation of misfolded or unfolded proteins in the endoplasmic reticulum lumen; this accumulation may be stimulated by genetic or environmental factors") AnnotationAssertion( "increased ER stress") +AnnotationAssertion( "enhanced ER stress") +AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "MP:0020354") AnnotationAssertion(rdfs:label "increased endoplasmic reticulum stress") SubClassOf( ) @@ -187619,6 +187624,19 @@ EquivalentClasses( ObjectSomeValuesFr SubClassOf( ) SubClassOf( ) +# Class: (decreased endoplasmic reticulum stress) + +AnnotationAssertion(Annotation( ) "reduction in the accumulation of misfolded or unfolded proteins in the endoplasmic reticulum lumen in response to stimulation by genetic or environmental factors") +AnnotationAssertion( "2024-02-19T12:21:35Z"^^xsd:dateTime) +AnnotationAssertion( ) +AnnotationAssertion( "decreased ER stress") +AnnotationAssertion( "reduced ER stress") +AnnotationAssertion( "reduced endoplasmic reticulum stress") +AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "MP:0031601") +AnnotationAssertion(rdfs:label "decreased endoplasmic reticulum stress") +SubClassOf( ) + # Class: (abnormal gastrula morphology) AnnotationAssertion(Annotation( "http://discovery.lifemapsc.com/library/review-of-medical-embryology/chapter-18-week-3-of-development-trilaminar-germ-disk-embryo-formation-and-gastrulation") "any structural anomaly of the pear shaped trilaminar embryonic stage in which the primititve streak elongates, the epiblast cells migrate medially towards the streak, enter the primitive groove and migrate laterally to organize into the intraembryonic mesoderm (epithelio-mesenchymal transition) between the embryonic ectoderm and primitive endoderm; the notochordal process forms and extends, and the disc becomes pear shaped as the notochordal process grows")