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abnormal CSF glucose level terms #4009

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anna-anagnostop opened this issue Jul 9, 2024 · 3 comments
Open

abnormal CSF glucose level terms #4009

anna-anagnostop opened this issue Jul 9, 2024 · 3 comments
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@anna-anagnostop
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anna-anagnostop commented Jul 9, 2024

J:281292 31399478 reports decreased CSF glucose levels in Slc2a1Rgsc200 heterozygotes. For now, I am annotating this to abnormal glucose homeostasis MP:0002078.

See https://en.wikipedia.org/wiki/CSF_glucose for causes of Low CSF glucose levels

Need to create new terms for:

abnormal cerebrospinal fluid glucose level
DEF: any deviation from the normal concentration of glucose in the cerebrospinal fluid
SYN: abnormal CSF glucose level
SOURCE: HP:0031884

decreased cerebrospinal fluid glucose level
DEF: less than the normal concentration of glucose in the cerebrospinal fluid
SYN: reduced cerebrospinal fluid glucose level
SYN: decreased CSF glucose level
SYN: reduced CSF glucose level
SYN: hypoglycorrhachia
SOURCE: HP:0011972, PMID:31399478

increased cerebrospinal fluid glucose level
DEF: greater than the normal concentration of glucose in the cerebrospinal fluid
SYN: elevated cerebrospinal fluid glucose level
SYN: increased CSF glucose level
SYN: elevated CSF glucose level
SYN: hyperglycorrhachia
SOURCE: HP:0031885

Should these be child terms of abnormal cerebrospinal fluid physiology MP:0021024 ? see child terms MP:0021027 and MP:0021082
Currently, there is no term available for abnormal cerebrospinal fluid composition.

@anna-anagnostop anna-anagnostop self-assigned this Jul 9, 2024
anna-anagnostop added a commit that referenced this issue Jul 22, 2024
@anna-anagnostop
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Added new terms:
abnormal cerebrospinal fluid glucose level MP:0031647
decreased cerebrospinal fluid glucose level MP:0031648
increased cerebrospinal fluid glucose level MP:0031649

@anna-anagnostop
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Move abnormal feces composition under digestive system morphology

TO DO:
Create new term abnormal cerebrospinal fluid composition under abnormal nervous system morphology.

Should level term in a bodily fluid be under physiology or under morphology branch?

anna-anagnostop added a commit that referenced this issue Jul 22, 2024
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Moved abnormal feces composition under digestive system morphology

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