gonadotropin-releasing hormone neuron terms

[anna-anagnostop]

Add new terms:

abnormal gonadotropin-releasing hormone neuron morphology (as a child of abnormal neuroendocrine cell morphology MP:0010913 AND abnormal hypothalamus morphology MP:0000837)
DEF: any structural anomaly of the neuroendocrine cell that secretes gonadotropin-releasing hormone (GnRH); a GnRH neuron is born in the nasal placode during embryonic development and migrates through the nose and forebrain to the hypothalamus; this cell regulates reproduction by secreting GnRH into the pituitary portal vessels to induce the release of gonadotropins into the general circulation
SYN: abnormal GnRH neuron morphology
SYN: abnormal GnRH-secreting neuron morphology
SOURCE: CL:0011111

Child terms include:

• abnormal gonadotropin-releasing hormone neuron number
• decreased gonadotropin-releasing hormone neuron number
• absent gonadotropin-releasing hormone neuron
• increased number gonadotropin-releasing hormone neuron number

Annotations currently scattered under abnormal neuron morphology MP:0002882, abnormal hypothalamus morphology MP:0000837 and abnormal neuroendocrine cell morphology MP:0010913. Most annotation relate to decreased number.