diff --git a/modules/programs/direnv.nix b/modules/programs/direnv.nix
index 6d0af3ac10d1..37899c4a2355 100644
--- a/modules/programs/direnv.nix
+++ b/modules/programs/direnv.nix
@@ -19,7 +19,7 @@ in {
       "Flake support is now always enabled.")
   ];
 
-  meta.maintainers = [ lib.maintainers.rycee ];
+  meta.maintainers = [ lib.maintainers.rycee lib.maintainers.shikanime ];
 
   options.programs.direnv = {
     enable = mkEnableOption "direnv, the environment switcher";
@@ -95,6 +95,14 @@ in {
       package = mkPackageOption pkgs "nix-direnv" { };
     };
 
+    mise = {
+      enable = mkEnableOption ''
+        [mise](https://mise.jdx.dev/direnv.html),
+        integration of use_mise for direnv'';
+
+      package = mkPackageOption pkgs "mise" { };
+    };
+
     silent = mkEnableOption "silent mode, that is, disabling direnv logging";
   };
 
@@ -112,6 +120,12 @@ in {
     xdg.configFile."direnv/direnvrc" =
       lib.mkIf (cfg.stdlib != "") { text = cfg.stdlib; };
 
+    xdg.configFile."direnv/lib/hm-mise.sh" = mkIf cfg.mise.enable {
+      text = ''
+        eval "$(${getExe cfg.mise.package} direnv activate)"
+      '';
+    };
+
     programs.bash.initExtra = mkIf cfg.enableBashIntegration (
       # Using mkAfter to make it more likely to appear after other
       # manipulations of the prompt.
diff --git a/tests/modules/programs/direnv/default.nix b/tests/modules/programs/direnv/default.nix
index a0e618481f83..b61fb1e334ed 100644
--- a/tests/modules/programs/direnv/default.nix
+++ b/tests/modules/programs/direnv/default.nix
@@ -1,5 +1,6 @@
 {
   direnv-bash = ./bash.nix;
+  direnv-mise = ./mise.nix;
   direnv-nix-direnv = ./nix-direnv.nix;
   direnv-nushell = ./nushell.nix;
   direnv-stdlib = ./stdlib.nix;
diff --git a/tests/modules/programs/direnv/mise.nix b/tests/modules/programs/direnv/mise.nix
new file mode 100644
index 000000000000..b205df6274ef
--- /dev/null
+++ b/tests/modules/programs/direnv/mise.nix
@@ -0,0 +1,17 @@
+{ config, ... }:
+
+{
+  programs.bash.enable = true;
+  programs.direnv = {
+    enable = true;
+    mise = {
+      enable = true;
+      package = config.lib.test.mkStubPackage { name = "mise"; };
+    };
+  };
+
+  nmt.script = ''
+    assertFileExists home-files/.bashrc
+    assertFileExists home-files/.config/direnv/lib/hm-mise.sh
+  '';
+}