diff --git a/src/lib.rs b/src/lib.rs
index 1a096c2934..955e756ee7 100644
--- a/src/lib.rs
+++ b/src/lib.rs
@@ -69,7 +69,7 @@ mod macros;
 // type that allows larger offsets to be used. We define our own off_t type
 // that is large enough to represent all file offsets the platform supports.
 cfg_if! {
-    if #[cfg(all(target_os = "linux", target_env = "gnu"))] {
+    if #[cfg(any(all(target_os = "linux", target_env = "gnu"), target_env = "uclibc"))] {
         /// Used to represent offsets in files. May differ from libc::off_t
         /// on platforms where libc::off_t cannot represent the full range
         /// of file offsets.
diff --git a/src/macros.rs b/src/macros.rs
index d85b0da8cf..410e72e142 100644
--- a/src/macros.rs
+++ b/src/macros.rs
@@ -333,7 +333,7 @@ macro_rules! libc_enum {
 }
 
 cfg_if! {
-    if #[cfg(all(target_os = "linux", target_env = "gnu"))] {
+    if #[cfg(any(all(target_os = "linux", target_env = "gnu"), target_env = "uclibc"))] {
         /// Function variant that supports large file positions.
         ///
         /// On some platforms, the standard I/O functions support a limited
diff --git a/src/sys/uio.rs b/src/sys/uio.rs
index e90890120f..a9240fe8e4 100644
--- a/src/sys/uio.rs
+++ b/src/sys/uio.rs
@@ -50,9 +50,6 @@ pub fn pwritev<Fd: AsFd, Off: Into<off_t>>(
     iov: &[IoSlice<'_>],
     offset: Off,
 ) -> Result<usize> {
-    #[cfg(target_env = "uclibc")]
-    let offset = offset as libc::off64_t; // uclibc doesn't use off_t
-
     // SAFETY: same as in writev()
     let res = unsafe {
         largefile_fn![pwritev](
@@ -80,9 +77,6 @@ pub fn preadv<Fd: AsFd, Off: Into<off_t>>(
     iov: &mut [IoSliceMut<'_>],
     offset: Off,
 ) -> Result<usize> {
-    #[cfg(target_env = "uclibc")]
-    let offset = offset as libc::off64_t; // uclibc doesn't use off_t
-
     // SAFETY: same as in readv()
     let res = unsafe {
         largefile_fn![preadv](