diff --git a/CHANGELOG.md b/CHANGELOG.md
index 66d8455859aa..e17bb7d1a207 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -55,6 +55,7 @@ Inspired from [Keep a Changelog](https://keepachangelog.com/en/1.0.0/)
 - [Chrome] Introduce registerCollapsibleNavHeader to allow plugins to customize the rendering of nav menu header ([#5244](https://github.com/opensearch-project/OpenSearch-Dashboards/pull/5244))
 - [Dynamic Configurations] Pass request headers when making application config calls ([#6164](https://github.com/opensearch-project/OpenSearch-Dashboards/pull/6164))
 - [Discover] Options button to configure legacy mode and remove the top navigation option ([#6170](https://github.com/opensearch-project/OpenSearch-Dashboards/pull/6170))
+- [Multiple Datasource] Add default functionality for customer to choose default datasource ([#6058](https://github.com/opensearch-project/OpenSearch-Dashboards/issues/6058))
 
 
 ### 🐛 Bug Fixes
diff --git a/src/plugins/data_source_management/public/components/edit_data_source/components/edit_form/edit_data_source_form.test.tsx b/src/plugins/data_source_management/public/components/edit_data_source/components/edit_form/edit_data_source_form.test.tsx
index 06d0af486bba..e5f73c503f6e 100644
--- a/src/plugins/data_source_management/public/components/edit_data_source/components/edit_form/edit_data_source_form.test.tsx
+++ b/src/plugins/data_source_management/public/components/edit_data_source/components/edit_form/edit_data_source_form.test.tsx
@@ -76,8 +76,10 @@ describe('Datasource Management: Edit Datasource Form', () => {
           <EditDataSourceForm
             existingDataSource={mockDataSourceAttributesWithAuth}
             existingDatasourceNamesList={existingDatasourceNamesList}
+            isDefault={false}
             onDeleteDataSource={mockFn}
             handleSubmit={mockFn}
+            onSetDefaultDataSource={mockFn}
             handleTestConnection={mockFn}
             displayToastMessage={mockFn}
           />
@@ -245,7 +247,9 @@ describe('Datasource Management: Edit Datasource Form', () => {
           <EditDataSourceForm
             existingDataSource={mockDataSourceAttributesWithNoAuth}
             existingDatasourceNamesList={existingDatasourceNamesList}
+            isDefault={false}
             onDeleteDataSource={mockFn}
+            onSetDefaultDataSource={mockFn}
             handleSubmit={mockFn}
             handleTestConnection={mockFn}
             displayToastMessage={mockFn}
@@ -301,6 +305,12 @@ describe('Datasource Management: Edit Datasource Form', () => {
       expect(mockFn).toHaveBeenCalled();
     });
 
+    test('should set as the default datasource from header', () => {
+      // @ts-ignore
+      component.find('Header').prop('onClickSetDefault')();
+      expect(mockFn).toHaveBeenCalled();
+    });
+
     /* Save Changes */
     test('should update the form with NoAuth on click save changes', async () => {
       await new Promise((resolve) =>
@@ -383,8 +393,10 @@ describe('With Registered Authentication', () => {
         <EditDataSourceForm
           existingDataSource={mockDataSourceAttributesWithNoAuth}
           existingDatasourceNamesList={existingDatasourceNamesList}
+          isDefault={false}
           onDeleteDataSource={jest.fn()}
           handleSubmit={jest.fn()}
+          onSetDefaultDataSource={jest.fn()}
           handleTestConnection={jest.fn()}
           displayToastMessage={jest.fn()}
         />
@@ -422,8 +434,10 @@ describe('With Registered Authentication', () => {
         <EditDataSourceForm
           existingDataSource={mockDataSourceAttributesWithRegisteredAuth}
           existingDatasourceNamesList={existingDatasourceNamesList}
+          isDefault={false}
           onDeleteDataSource={jest.fn()}
           handleSubmit={mockedSubmitHandler}
+          onSetDefaultDataSource={jest.fn()}
           handleTestConnection={jest.fn()}
           displayToastMessage={jest.fn()}
         />
diff --git a/src/plugins/data_source_management/public/components/edit_data_source/components/edit_form/edit_data_source_form.tsx b/src/plugins/data_source_management/public/components/edit_data_source/components/edit_form/edit_data_source_form.tsx
index 2cb1db4515dd..6714881c4a11 100644
--- a/src/plugins/data_source_management/public/components/edit_data_source/components/edit_form/edit_data_source_form.tsx
+++ b/src/plugins/data_source_management/public/components/edit_data_source/components/edit_form/edit_data_source_form.tsx
@@ -50,9 +50,11 @@ import { extractRegisteredAuthTypeCredentials, getDefaultAuthMethod } from '../.
 export interface EditDataSourceProps {
   existingDataSource: DataSourceAttributes;
   existingDatasourceNamesList: string[];
+  isDefault: boolean;
   handleSubmit: (formValues: DataSourceAttributes) => Promise<void>;
   handleTestConnection: (formValues: DataSourceAttributes) => Promise<void>;
   onDeleteDataSource?: () => Promise<void>;
+  onSetDefaultDataSource: () => Promise<void>;
   displayToastMessage: (info: ToastMessageItem) => void;
 }
 export interface EditDataSourceState {
@@ -400,6 +402,12 @@ export class EditDataSourceForm extends React.Component<EditDataSourceProps, Edi
     }
   };
 
+  setDefaultDataSource = async () => {
+    if (this.props.onSetDefaultDataSource) {
+      await this.props.onSetDefaultDataSource();
+    }
+  };
+
   onClickTestConnection = async () => {
     this.setState({ isLoading: true });
     const isNewCredential = !!(this.state.auth.type !== this.props.existingDataSource.auth.type);
@@ -634,6 +642,8 @@ export class EditDataSourceForm extends React.Component<EditDataSourceProps, Edi
         onClickDeleteIcon={this.onClickDeleteDataSource}
         dataSourceName={this.props.existingDataSource.title}
         onClickTestConnection={this.onClickTestConnection}
+        onClickSetDefault={this.setDefaultDataSource}
+        isDefault={this.props.isDefault}
       />
     );
   };
diff --git a/src/plugins/data_source_management/public/components/edit_data_source/components/header/header.test.tsx b/src/plugins/data_source_management/public/components/edit_data_source/components/header/header.test.tsx
index f679a7db6e67..5a23b72881a1 100644
--- a/src/plugins/data_source_management/public/components/edit_data_source/components/header/header.test.tsx
+++ b/src/plugins/data_source_management/public/components/edit_data_source/components/header/header.test.tsx
@@ -14,6 +14,7 @@ import { act } from 'react-dom/test-utils';
 const headerTitleIdentifier = '[data-test-subj="editDataSourceTitle"]';
 const deleteIconIdentifier = '[data-test-subj="editDatasourceDeleteIcon"]';
 const confirmModalIdentifier = '[data-test-subj="editDatasourceDeleteConfirmModal"]';
+const setDefaultButtonIdentifier = '[data-test-subj="editSetDefaultDataSource"]';
 
 describe('Datasource Management: Edit Datasource Header', () => {
   const mockedContext = mockManagementPlugin.createDataSourceManagementContext();
@@ -31,6 +32,8 @@ describe('Datasource Management: Edit Datasource Header', () => {
             onClickDeleteIcon={mockFn}
             onClickTestConnection={mockFn}
             dataSourceName={dataSourceName}
+            onClickSetDefault={mockFn}
+            isDefault={false}
           />
         ),
         {
@@ -82,6 +85,8 @@ describe('Datasource Management: Edit Datasource Header', () => {
             onClickDeleteIcon={mockFn}
             onClickTestConnection={mockFn}
             dataSourceName={dataSourceName}
+            onClickSetDefault={mockFn}
+            isDefault={false}
           />
         ),
         {
@@ -97,4 +102,76 @@ describe('Datasource Management: Edit Datasource Header', () => {
       expect(component.find(deleteIconIdentifier).exists()).toBe(false);
     });
   });
+  describe('should render default icon as "Set as default" when isDefaultDataSourceState is false', () => {
+    const onClickSetDefault = jest.fn();
+    const isDefaultDataSourceState = false;
+    beforeEach(() => {
+      component = mount(
+        wrapWithIntl(
+          <Header
+            isFormValid={true}
+            showDeleteIcon={true}
+            onClickDeleteIcon={mockFn}
+            onClickTestConnection={mockFn}
+            dataSourceName={dataSourceName}
+            onClickSetDefault={onClickSetDefault}
+            isDefault={isDefaultDataSourceState}
+          />
+        ),
+        {
+          wrappingComponent: OpenSearchDashboardsContextProvider,
+          wrappingComponentProps: {
+            services: mockedContext,
+          },
+        }
+      );
+    });
+
+    test('should render normally', () => {
+      expect(component.find(setDefaultButtonIdentifier).exists()).toBe(true);
+    });
+    test('default button should show as "Set as default" and should be clickable', () => {
+      expect(component.find(setDefaultButtonIdentifier).first().text()).toBe('Set as default');
+      expect(component.find(setDefaultButtonIdentifier).first().prop('disabled')).toBe(false);
+      expect(component.find(setDefaultButtonIdentifier).first().prop('iconType')).toBe('starEmpty');
+      component.find(setDefaultButtonIdentifier).first().simulate('click');
+      expect(onClickSetDefault).toHaveBeenCalled();
+    });
+  });
+  describe('should render default icon as "Default" when isDefaultDataSourceState is true', () => {
+    const onClickSetDefault = jest.fn();
+    const isDefaultDataSourceState = true;
+    beforeEach(() => {
+      component = mount(
+        wrapWithIntl(
+          <Header
+            isFormValid={true}
+            showDeleteIcon={true}
+            onClickDeleteIcon={mockFn}
+            onClickTestConnection={mockFn}
+            dataSourceName={dataSourceName}
+            onClickSetDefault={onClickSetDefault}
+            isDefault={isDefaultDataSourceState}
+          />
+        ),
+        {
+          wrappingComponent: OpenSearchDashboardsContextProvider,
+          wrappingComponentProps: {
+            services: mockedContext,
+          },
+        }
+      );
+    });
+
+    test('should render normally', () => {
+      expect(component.find(setDefaultButtonIdentifier).exists()).toBe(true);
+    });
+    test('default button should show as "Default" and should be disabled.', () => {
+      expect(component.find(setDefaultButtonIdentifier).first().text()).toBe('Default');
+      expect(component.find(setDefaultButtonIdentifier).first().prop('disabled')).toBe(true);
+      expect(component.find(setDefaultButtonIdentifier).first().prop('iconType')).toBe(
+        'starFilled'
+      );
+    });
+  });
 });
diff --git a/src/plugins/data_source_management/public/components/edit_data_source/components/header/header.tsx b/src/plugins/data_source_management/public/components/edit_data_source/components/header/header.tsx
index 49c100b7ec9a..264647882574 100644
--- a/src/plugins/data_source_management/public/components/edit_data_source/components/header/header.tsx
+++ b/src/plugins/data_source_management/public/components/edit_data_source/components/header/header.tsx
@@ -14,6 +14,7 @@ import {
   EuiButtonIcon,
   EuiConfirmModal,
   EuiButton,
+  EuiButtonEmpty,
 } from '@elastic/eui';
 import { i18n } from '@osd/i18n';
 import { FormattedMessage } from '@osd/i18n/react';
@@ -25,22 +26,51 @@ export const Header = ({
   isFormValid,
   onClickDeleteIcon,
   onClickTestConnection,
+  onClickSetDefault,
   dataSourceName,
+  isDefault,
 }: {
   showDeleteIcon: boolean;
   isFormValid: boolean;
   onClickDeleteIcon: () => void;
   onClickTestConnection: () => void;
+  onClickSetDefault: () => void;
   dataSourceName: string;
+  isDefault: boolean;
 }) => {
   /* State Variables */
   const [isDeleteModalVisible, setIsDeleteModalVisible] = useState(false);
+  const [isDefaultDataSourceState, setIsDefaultDataSourceState] = useState(isDefault);
 
   const changeTitle = useOpenSearchDashboards<DataSourceManagementContext>().services.chrome
     .docTitle.change;
 
   changeTitle(dataSourceName);
 
+  const setDefaultAriaLabel = i18n.translate(
+    'dataSourcesManagement.editDataSource.setDefaultDataSource',
+    {
+      defaultMessage: 'Set as a default Data Source.',
+    }
+  );
+
+  const renderDefaultIcon = () => {
+    return (
+      <EuiButtonEmpty
+        onClick={() => {
+          onClickSetDefault();
+          setIsDefaultDataSourceState(!isDefaultDataSourceState);
+        }}
+        disabled={isDefaultDataSourceState}
+        iconType={isDefaultDataSourceState ? 'starFilled' : 'starEmpty'}
+        aria-label={setDefaultAriaLabel}
+        data-test-subj="editSetDefaultDataSource"
+      >
+        {isDefaultDataSourceState ? 'Default' : 'Set as default'}
+      </EuiButtonEmpty>
+    );
+  };
+
   const renderDeleteButton = () => {
     return (
       <>
@@ -144,6 +174,8 @@ export const Header = ({
       {/* Right side buttons */}
       <EuiFlexItem grow={false}>
         <EuiFlexGroup alignItems="baseline" gutterSize="m" responsive={false}>
+          {/* Test default button */}
+          <EuiFlexItem grow={false}>{renderDefaultIcon()}</EuiFlexItem>
           {/* Test connection button */}
           <EuiFlexItem grow={false}>{renderTestConnectionButton()}</EuiFlexItem>
           {/* Delete icon button */}
diff --git a/src/plugins/data_source_management/public/components/edit_data_source/edit_data_source.test.tsx b/src/plugins/data_source_management/public/components/edit_data_source/edit_data_source.test.tsx
index c1516a507d4a..6cab62b49c8c 100644
--- a/src/plugins/data_source_management/public/components/edit_data_source/edit_data_source.test.tsx
+++ b/src/plugins/data_source_management/public/components/edit_data_source/edit_data_source.test.tsx
@@ -29,6 +29,7 @@ const notFoundIdentifier = '[data-test-subj="dataSourceNotFound"]';
 
 describe('Datasource Management: Edit Datasource Wizard', () => {
   const mockedContext = mockManagementPlugin.createDataSourceManagementContext();
+  const uiSettings = mockedContext.uiSettings;
   mockedContext.authenticationMethodRegistery.registerAuthenticationMethod(
     noAuthCredentialAuthMethod
   );
@@ -125,6 +126,16 @@ describe('Datasource Management: Edit Datasource Wizard', () => {
       component.update();
       expect(utils.updateDataSourceById).toHaveBeenCalled();
     });
+    test('should set default data source', async () => {
+      spyOn(uiSettings, 'set').and.returnValue({});
+      await act(async () => {
+        // @ts-ignore
+        await component.find(formIdentifier).first().prop('onSetDefaultDataSource')(
+          mockDataSourceAttributesWithAuth
+        );
+      });
+      expect(uiSettings.set).toHaveBeenCalled();
+    });
     test('should delete datasource successfully', async () => {
       spyOn(utils, 'deleteDataSourceById').and.returnValue({});
 
diff --git a/src/plugins/data_source_management/public/components/edit_data_source/edit_data_source.tsx b/src/plugins/data_source_management/public/components/edit_data_source/edit_data_source.tsx
index bc2bac5b66b8..46e253b2b85b 100644
--- a/src/plugins/data_source_management/public/components/edit_data_source/edit_data_source.tsx
+++ b/src/plugins/data_source_management/public/components/edit_data_source/edit_data_source.tsx
@@ -38,6 +38,7 @@ export const EditDataSource: React.FunctionComponent<RouteComponentProps<{ id: s
 ) => {
   /* Initialization */
   const {
+    uiSettings,
     savedObjects,
     setBreadcrumbs,
     http,
@@ -83,6 +84,12 @@ export const EditDataSource: React.FunctionComponent<RouteComponentProps<{ id: s
     }
   };
 
+  const handleSetDefault = async () => {
+    await uiSettings.set('defaultDataSource', dataSourceID);
+  };
+
+  const isDefaultDataSource = uiSettings.get('defaultDataSource', null) === dataSourceID;
+
   /* Handle submit - create data source*/
   const handleSubmit = async (attributes: DataSourceAttributes) => {
     await updateDataSourceById(savedObjects.client, dataSourceID, attributes);
@@ -128,7 +135,9 @@ export const EditDataSource: React.FunctionComponent<RouteComponentProps<{ id: s
           <EditDataSourceForm
             existingDataSource={dataSource}
             existingDatasourceNamesList={existingDatasourceNamesList}
+            isDefault={isDefaultDataSource}
             onDeleteDataSource={handleDelete}
+            onSetDefaultDataSource={handleSetDefault}
             handleSubmit={handleSubmit}
             displayToastMessage={handleDisplayToastMessage}
             handleTestConnection={handleTestConnection}