diff --git a/src/main/resources/interface-specification.yml b/src/main/resources/interface-specification.yml
index ff5e4f2a..4becb779 100644
--- a/src/main/resources/interface-specification.yml
+++ b/src/main/resources/interface-specification.yml
@@ -264,6 +264,12 @@ paths:
             application/problem+json:
               schema:
                 $ref: '#/components/schemas/Problem'
+        '409':
+          description: E-Service has some descriptors
+          content:
+            application/problem+json:
+              schema:
+                $ref: '#/components/schemas/Problem'
   /eservices/{eServiceId}/consumers:
     parameters:
       - $ref: '#/components/parameters/CorrelationIdHeader'
diff --git a/src/main/scala/it/pagopa/interop/catalogprocess/api/impl/ResponseHandlers.scala b/src/main/scala/it/pagopa/interop/catalogprocess/api/impl/ResponseHandlers.scala
index ec6ced1a..cc5ebcad 100644
--- a/src/main/scala/it/pagopa/interop/catalogprocess/api/impl/ResponseHandlers.scala
+++ b/src/main/scala/it/pagopa/interop/catalogprocess/api/impl/ResponseHandlers.scala
@@ -102,10 +102,11 @@ object ResponseHandlers extends AkkaResponses {
     success: T => Route
   )(result: Try[T])(implicit contexts: Seq[(String, String)], logger: LoggerTakingImplicit[ContextFieldsToLog]): Route =
     result match {
-      case Success(s)                           => success(s)
-      case Failure(ex: OperationForbidden.type) => forbidden(ex, logMessage)
-      case Failure(ex: EServiceNotFound)        => notFound(ex, logMessage)
-      case Failure(ex)                          => internalServerError(ex, logMessage)
+      case Success(s)                                       => success(s)
+      case Failure(ex: OperationForbidden.type)             => forbidden(ex, logMessage)
+      case Failure(ex: EServiceNotFound)                    => notFound(ex, logMessage)
+      case Failure(ex: EServiceWithDescriptorsNotDeletable) => conflict(ex, logMessage)
+      case Failure(ex)                                      => internalServerError(ex, logMessage)
     }
 
   def activateDescriptorResponse[T](logMessage: String)(
diff --git a/src/main/scala/it/pagopa/interop/catalogprocess/errors/CatalogProcessErrors.scala b/src/main/scala/it/pagopa/interop/catalogprocess/errors/CatalogProcessErrors.scala
index 484ce0db..a5b71725 100644
--- a/src/main/scala/it/pagopa/interop/catalogprocess/errors/CatalogProcessErrors.scala
+++ b/src/main/scala/it/pagopa/interop/catalogprocess/errors/CatalogProcessErrors.scala
@@ -76,7 +76,10 @@ object CatalogProcessErrors {
   final case class AttributeNotFound(attributeId: UUID)
       extends ComponentError("0020", s"Attribute ${attributeId.toString} not found")
 
+  final case class EServiceWithDescriptorsNotDeletable(eServiceId: String)
+      extends ComponentError("0021", s"EService $eServiceId contains descriptors and cannot be deleted")
+
   final case class InterfaceAlreadyExists(descriptorId: UUID)
-      extends ComponentError("0021", s"Descriptor ${descriptorId.toString} already has an interface")
+      extends ComponentError("0022", s"Descriptor ${descriptorId.toString} already has an interface")
 
 }
diff --git a/src/main/scala/it/pagopa/interop/catalogprocess/service/impl/CatalogManagementServiceImpl.scala b/src/main/scala/it/pagopa/interop/catalogprocess/service/impl/CatalogManagementServiceImpl.scala
index 74243985..1b59ce00 100644
--- a/src/main/scala/it/pagopa/interop/catalogprocess/service/impl/CatalogManagementServiceImpl.scala
+++ b/src/main/scala/it/pagopa/interop/catalogprocess/service/impl/CatalogManagementServiceImpl.scala
@@ -20,7 +20,8 @@ import it.pagopa.interop.catalogprocess.errors.CatalogProcessErrors.{
   DescriptorDocumentNotFound,
   EServiceDescriptorNotFound,
   EServiceNotFound,
-  EServiceRiskAnalysisNotFound
+  EServiceRiskAnalysisNotFound,
+  EServiceWithDescriptorsNotDeletable
 }
 import it.pagopa.interop.commons.logging.{CanLogContextFields, ContextFieldsToLog}
 
@@ -74,6 +75,7 @@ final case class CatalogManagementServiceImpl(invoker: CatalogManagementInvoker,
       invoker.invoke(request, s"E-Service $eServiceId deleted").recoverWith {
         case err: ApiError[_] if err.code == 404 =>
           Future.failed(EServiceNotFound(eServiceId))
+        case err: ApiError[_] if err.code == 409 => Future.failed(EServiceWithDescriptorsNotDeletable(eServiceId))
       }
     }
 
diff --git a/src/test/scala/it/pagopa/interop/catalogprocess/CatalogProcessSpec.scala b/src/test/scala/it/pagopa/interop/catalogprocess/CatalogProcessSpec.scala
index 04ecaf6e..bb1e658b 100644
--- a/src/test/scala/it/pagopa/interop/catalogprocess/CatalogProcessSpec.scala
+++ b/src/test/scala/it/pagopa/interop/catalogprocess/CatalogProcessSpec.scala
@@ -18,7 +18,8 @@ import it.pagopa.interop.catalogprocess.errors.CatalogProcessErrors.{
   DescriptorDocumentNotFound,
   EServiceNotFound,
   EServiceRiskAnalysisNotFound,
-  AttributeNotFound
+  AttributeNotFound,
+  EServiceWithDescriptorsNotDeletable
 }
 import it.pagopa.interop.catalogprocess.model._
 import it.pagopa.interop.commons.cqrs.service.ReadModelService
@@ -2378,14 +2379,12 @@ class CatalogProcessSpec extends SpecHelper with AnyWordSpecLike with ScalatestR
   "EService deletion" should {
     "succeed" in {
 
-      val requesterId                             = UUID.randomUUID()
-      val descriptorId                            = UUID.randomUUID()
+      val requesterId = UUID.randomUUID()
+
       implicit val context: Seq[(String, String)] =
         Seq("bearer" -> bearerToken, USER_ROLES -> "admin", ORGANIZATION_ID_CLAIM -> requesterId.toString)
 
-      val descriptor = SpecData.catalogDescriptor.copy(id = descriptorId)
-
-      val eService = SpecData.catalogItem.copy(descriptors = Seq(descriptor), producerId = requesterId)
+      val eService = SpecData.catalogItem.copy(descriptors = Seq.empty, producerId = requesterId)
 
       (mockCatalogManagementService
         .getEServiceById(_: UUID)(_: ExecutionContext, _: ReadModelService))
@@ -2419,6 +2418,33 @@ class CatalogProcessSpec extends SpecHelper with AnyWordSpecLike with ScalatestR
         status shouldEqual StatusCodes.NotFound
       }
     }
+    "fail if EService has descriptors" in {
+
+      val requesterId                             = UUID.randomUUID()
+      val descriptorId                            = UUID.randomUUID()
+      implicit val context: Seq[(String, String)] =
+        Seq("bearer" -> bearerToken, USER_ROLES -> "admin", ORGANIZATION_ID_CLAIM -> requesterId.toString)
+
+      val descriptor = SpecData.catalogDescriptor.copy(id = descriptorId)
+
+      val eService = SpecData.catalogItem.copy(descriptors = Seq(descriptor), producerId = requesterId)
+
+      (mockCatalogManagementService
+        .getEServiceById(_: UUID)(_: ExecutionContext, _: ReadModelService))
+        .expects(SpecData.catalogItem.id, *, *)
+        .once()
+        .returns(Future.successful(eService))
+
+      (mockCatalogManagementService
+        .deleteEService(_: String)(_: Seq[(String, String)]))
+        .expects(eService.id.toString, *)
+        .returning(Future.failed(EServiceWithDescriptorsNotDeletable(SpecData.catalogItem.id.toString)))
+        .once()
+
+      Delete() ~> service.deleteEService(SpecData.catalogItem.id.toString) ~> check {
+        status shouldEqual StatusCodes.Conflict
+      }
+    }
     "fail if requester is not the Producer" in {
       implicit val context: Seq[(String, String)] =
         Seq("bearer" -> bearerToken, USER_ROLES -> "admin", ORGANIZATION_ID_CLAIM -> UUID.randomUUID().toString)