diff --git a/.changeset/grumpy-clocks-sell.md b/.changeset/grumpy-clocks-sell.md
new file mode 100644
index 00000000000..0c3a965a89b
--- /dev/null
+++ b/.changeset/grumpy-clocks-sell.md
@@ -0,0 +1,5 @@
+---
+'@primer/react': patch
+---
+
+Adds `aria-disabled` to inactive pagination buttons.
diff --git a/src/DataTable/Pagination.tsx b/src/DataTable/Pagination.tsx
index 2769a4e943e..9dc14038e50 100644
--- a/src/DataTable/Pagination.tsx
+++ b/src/DataTable/Pagination.tsx
@@ -226,6 +226,7 @@ export function Pagination({
               className="TablePaginationAction"
               type="button"
               data-has-page={hasPreviousPage ? true : undefined}
+              aria-disabled={!hasPreviousPage ? true : undefined}
               onClick={() => {
                 if (!hasPreviousPage) {
                   return
@@ -306,6 +307,7 @@ export function Pagination({
               className="TablePaginationAction"
               type="button"
               data-has-page={hasNextPage ? true : undefined}
+              aria-disabled={!hasNextPage ? true : undefined}
               onClick={() => {
                 if (!hasNextPage) {
                   return