diff --git a/Python/bytecodes.c b/Python/bytecodes.c
index 2c78cb9931733d..81b527e8c050b9 100644
--- a/Python/bytecodes.c
+++ b/Python/bytecodes.c
@@ -197,7 +197,7 @@ dummy_func(
                 _Py_CODEUNIT *bytecode =
                     _PyEval_GetExecutableCode(tstate, _PyFrame_GetCode(frame));
                 ERROR_IF(bytecode == NULL, error);
-                int off = this_instr - _PyFrame_GetBytecode(frame);
+                ptrdiff_t off = this_instr - _PyFrame_GetBytecode(frame);
                 frame->tlbc_index = ((_PyThreadStateImpl *)tstate)->tlbc_index;
                 frame->instr_ptr = bytecode + off;
                 // Make sure this_instr gets reset correctley for any uops that
diff --git a/Python/generated_cases.c.h b/Python/generated_cases.c.h
index eff246f1997276..c6b8fbc50f388a 100644
--- a/Python/generated_cases.c.h
+++ b/Python/generated_cases.c.h
@@ -4841,7 +4841,7 @@
                     stack_pointer = _PyFrame_GetStackPointer(frame);
                     if (bytecode == NULL) goto error;
                     _PyFrame_SetStackPointer(frame, stack_pointer);
-                    int off = this_instr - _PyFrame_GetBytecode(frame);
+                    ptrdiff_t off = this_instr - _PyFrame_GetBytecode(frame);
                     stack_pointer = _PyFrame_GetStackPointer(frame);
                     frame->tlbc_index = ((_PyThreadStateImpl *)tstate)->tlbc_index;
                     frame->instr_ptr = bytecode + off;
@@ -6898,7 +6898,7 @@
                     stack_pointer = _PyFrame_GetStackPointer(frame);
                     if (bytecode == NULL) goto error;
                     _PyFrame_SetStackPointer(frame, stack_pointer);
-                    int off = this_instr - _PyFrame_GetBytecode(frame);
+                    ptrdiff_t off = this_instr - _PyFrame_GetBytecode(frame);
                     stack_pointer = _PyFrame_GetStackPointer(frame);
                     frame->tlbc_index = ((_PyThreadStateImpl *)tstate)->tlbc_index;
                     frame->instr_ptr = bytecode + off;