README.md

This is a netpyne implementation of the Dentite Gyrus model

Requirements:

- Python3
- Neuron 7.6.2
- NetPyNE

Run:

- `git clone https://github.com/rodriguez-facundo/LASCON-project.git`
- `cd LASCON-project`
- `nrnivmodl mod`
- `nrniv -python init.py`

To change network composition, choose a different file from init.py line 169:

• morpho/100A0Y.dat (only mature cells)
• morpho/50A50Y.dat (mature & young)
• morpho/50A50P.dat (mature & PILO treated)

You can also control the sprouting level from the diver matrix at line 196 (init.py). (last row, last colum)

NOTES: - The calcium activated Potassium channel does not work outside 6.3 degrees unless you set q10 = 1 and recompile mod files. - Templates n5, n111, n112 present disconected sections. You can choose other templates instead.

Some results playing with the model:

Connectivity

Rasters

NetPyNE-UI network viewer