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Nyxus provided features

Pixel intensity features:


Nyxus feature code Description
INTEGRATED_INTENSITY Integrated intensity of the region of interest (ROI)
MEAN Mean intensity value of the ROI
MEDIAN The median value of pixels in the ROI
MIN Minimum intensity value in the ROI
MAX Maximum intensity value in the ROI
RANGE Range between the maximmu and minimum
COVERED_IMAGE_INTENSITY_RANGE intensity range of the ROI to intensity range of all the ROIs
STANDARD_DEVIATION Standard deviation (unbiased)
STANDARD_DEVIATION_BIASED Biased standard deviation
COV Coefficient of variation
STANDARD_ERROR Standard error
SKEWNESS Skewness - the 3rd standardized moment
KURTOSIS Kurtosis - the 4th standardized moment (Pearson formula)
EXCESS_KURTOSIS Excess kurtosis - the 4th standardized moment (Fisher-corrected formula, IBSI feature IPH6)
HYPERSKEWNESS Hyperskewness - the 5th standardized moment
HYPERFLATNESS Hyperflatness - the 6th standardized moment
MEAN_ABSOLUTE_DEVIATION Mean absolute deviation
MEDIAN_ABSOLUTE_DEVIATION Median absolute deviation
ENERGY ROI energy
ROOT_MEAN_SQUARED Root of mean squared deviation
ENTROPY ROI entropy - a measure of the amount of information (that is, randomness) in the ROI
MODE The mode value of pixels in the ROI - the value that appears most often in a set of ROI intensity values
UNIFORMITY Uniformity - measures how uniform the distribution of ROI intensities is
UNIFORMITY_PIU Percent image uniformity, another measure of intensity distribution uniformity
P01, P10, P25, P75, P90, P99 1%, 10%, 25%, 75%, 90%, and 99% percentiles of intensity distribution
QCOD quantile coefficient of dispersion
INTERQUARTILE_RANGE Distribution's interquartile range
ROBUST_MEAN_ABSOLUTE_DEVIATION Robust mean absolute deviation
MASS_DISPLACEMENT ROI mass displacement

Morphology features:


Nyxus feature code Description
AREA_PIXELS_COUNT ROI area in the number of pixels
AREA_UM2 ROI area in metric units
CENTROID_X X-coordinate of the enter point of the ROI
CENTROID_Y Y-coordinate of the center point of the ROI
COMPACTNESS Mean squared distance of the object’s pixels from the centroid divided by the area. Compactness of a filled circle is 1, compactness of irregular objects or objects with holes is greater than 1
BBOX_YMIN Y-position and size of the smallest axis-aligned box containing the ROI
BBOX_XMIN X-position and size of the smallest axis-aligned box containing the ROI
BBOX_HEIGHT Height of the smallest axis-aligned box containing the ROI
BBOX_WIDTH Width of the smallest axis-aligned box containing the ROI
MAJOR_AXIS_LENGTH Length (in pixels) of the major axis of the ellipse that has the same normalized second central moments as the region
MINOR_AXIS_LENGTH Length (in pixels) of the minor axis of the ellipse that has the same normalized second central moments as the region
ECCENTRICITY Ratio of ROI's inertia ellipse focal distance over the major axis length
ORIENTATION Angle between the 0th axis and the major axis of the ellipse that has same second moments as the region
ROUNDNESS Represents how similar a ROI's inertia ellipse is to circle. Calculated based on the major and minor exis lengths
EXTENT Proportion of the pixels (2D) or voxels (3D) in the bounding box that are also in the region. Computed as the area/volume of the object divided by the area/volume of the bounding box
ASPECT_RATIO The ratio of the major axis to the minor axis of ROI's inertia ellipse
CONVEX_HULL_AREA Area of ROI's convex hull
SOLIDITY Ratio of pixels in the ROI common with its convex hull image
PERIMETER Number of pixels in ROI's contour
EQUIVALENT_DIAMETER Diameter of a circle with the same area as the ROI
EDGE_MEAN_INTENSITY Mean intensity of ROI's contour pixels
EDGE_STDDEV_INTENSITY Standard deviation of ROI's contour pixels
EDGE_MAX_INTENSITY Maximum intensity of ROI's contour pixels
EDGE_MIN_INTENSITY Minimum intensity of ROI's contour pixels
CIRCULARITY Represents how similar a shape is to circle. Clculated based on ROI's area and its convex perimeter
EROSIONS_2_VANISH Number of erosion operations for a ROI to vanish in its axis aligned bounding box
EROSIONS_2_VANISH_COMPLEMENT Number of erosion operations for a ROI to vanish in its convex hull
FRACT_DIM_BOXCOUNT Fractal dimension determined by the box counting method according to ISO 9276-6. If C is a fractal set, with fractal dimension DF < D, then the number N of boxes of size R needed to cover the set scales as R^(-DF). DF is known as the Hausdorf dimension, or Kolmogorov capacity, or Kolmogorov dimension, or simply box-counting dimension
FRACT_DIM_PERIMETER Fractal dimension determined by the perimeter method according to ISO 9276-6. If we approximate ROI's contour with rulers of length lambda, the perimeter based fractal dimension is the slope of the best fit line of log ROI perimeter versus log lambda, subtracted from 1
WEIGHTED_CENTROID_Y X-coordinate of centroid
WEIGHTED_CENTROID_X Y-coordinate of centroid
MIN_FERET_DIAMETER Feret diameter (or maximum caliber diameter) is the longest distance between any two ROI points along the same (horizontal) direction. This feature is the minimum Feret diameter for angles ranging 0 to 180 degrees
MAX_FERET_DIAMETER Maximum Feret diameter for angles ranging 0 to 180 degrees
MIN_FERET_ANGLE Angle of the minimum Feret diameter
MAX_FERET_ANGLE Angle of the maximum Feret diameter
STAT_FERET_DIAM_MIN Minimum of Feret diameters of the ROI rotated at angles 0-180 degrees
STAT_FERET_DIAM_MAX Maximum of Feret diameters of the ROI rotated at angles 0-180 degrees
STAT_FERET_DIAM_MEAN Mean Feret diameter of the ROI rotated at angles 0-180 degrees
STAT_FERET_DIAM_MEDIAN Median value of Feret diameters of the ROI rotated at angles 0-180 degrees
STAT_FERET_DIAM_STDDEV Standard deviation of Feret diameter of the ROI rotated at angles 0-180 degrees
STAT_FERET_DIAM_MODE Histogram mode of Feret diameters of the ROI rotated at angles 0-180 degrees
STAT_MARTIN_DIAM_MIN Minimum of Martin diameters of the ROI rotated at angles 0-180 degrees
STAT_MARTIN_DIAM_MAX Maximum of Martin diameters of the ROI rotated at angles 0-180 degrees
STAT_MARTIN_DIAM_MEAN Mean of Martin diameter of the ROI rotated at angles 0-180 degrees
STAT_MARTIN_DIAM_MEDIAN Median value of Martin diameters of the ROI rotated at angles 0-180 degrees
STAT_MARTIN_DIAM_STDDEV Standard deviation of Martin diameter of the ROI rotated at angles 0-180 degrees
STAT_MARTIN_DIAM_MODE Histogram mode of Martin diameters of the ROI rotated at angles 0-180 degrees
STAT_NASSENSTEIN_DIAM_MIN Minimum of Nassenstein diameters of the ROI rotated at angles 0-180 degrees
STAT_NASSENSTEIN_DIAM_MAX Maximum of Nassenstein diameters of the ROI rotated at angles 0-180 degrees
STAT_NASSENSTEIN_DIAM_MEAN Mean of Nassenstein diameter of the ROI rotated at angles 0-180 degrees
STAT_NASSENSTEIN_DIAM_MEDIAN Median value of Nassenstein diameters of the ROI rotated at angles 0-180 degrees
STAT_NASSENSTEIN_DIAM_STDDEV Standard deviation of Nassenstein diameter of the ROI rotated at angles 0-180 degrees
STAT_NASSENSTEIN_DIAM_MODE Histogram mode of Nassenstein diameters of the ROI rotated at angles 0-180 degrees
MAXCHORDS_MAX Maximum of ROI's longest chords built at angles 0-180 degrees
MAXCHORDS_MAX_ANG Angle of the chord referenced in MAXCHORDS_MAX
MAXCHORDS_MIN Minimum of ROI's longest chords built at angles 0-180 degrees
MAXCHORDS_MIN_ANG Angle of the chord referenced in MAXCHORDS_MIN
MAXCHORDS_MEDIAN Median value of ROI's longest chords built at angles 0-180 degrees
MAXCHORDS_MEAN Mean value of ROI's longest chords built at angles 0-180 degrees
MAXCHORDS_MODE Histogram mode of ROI's longest chords built at angles 0-180 degrees
MAXCHORDS_STDDEV Sndard deviation of ROI's longest chords built at angles 0-180 degrees
ALLCHORDS_MAX Maximum of all the ROI's chords built at angles 0-180 degrees
ALLCHORDS_MAX_ANG Angle of the chord referenced in ALLCHORDS_MAX
ALLCHORDS_MIN Minimum of all the ROI's chords built at angles 0-180 degrees
ALLCHORDS_MIN_ANG Angle of the chord referenced in ALLCHORDS_MIN
ALLCHORDS_MEDIAN Median value of all the ROI's chords built at angles 0-180 degrees
ALLCHORDS_MEAN Mean value of all the ROI's chords built at angles 0-180 degrees
ALLCHORDS_MODE Histogram mode of all the ROI's chords built at angles 0-180 degrees
ALLCHORDS_STDDEV Sndard deviation of all the ROI's chords built at angles 0-180 degrees
EULER_NUMBER Euler characteristic of the ROI - the number of objects in the ROI minus the number of holes assuming the 8-neighbor connectivity of ROI's pixels
EXTREMA_P1_X X-ccordinate of ROI's axis aligned bounding box extremum point #1
EXTREMA_P1_Y Y-ccordinate of ROI's axis aligned bounding box extremum point #1
EXTREMA_P2_X X-ccordinate of ROI's axis aligned bounding box extremum point #2
EXTREMA_P2_Y  
EXTREMA_P3_X X-ccordinate of ROI's axis aligned bounding box extremum point #3
EXTREMA_P3_Y  
EXTREMA_P4_X X-ccordinate of ROI's axis aligned bounding box extremum point #4
EXTREMA_P4_Y  
EXTREMA_P5_X X-ccordinate of ROI's axis aligned bounding box extremum point #5
EXTREMA_P5_Y  
EXTREMA_P6_X X-ccordinate of ROI's axis aligned bounding box extremum point #6
EXTREMA_P6_Y  
EXTREMA_P7_X X-ccordinate of ROI's axis aligned bounding box extremum point #7
EXTREMA_P7_Y  
EXTREMA_P8_X X-ccordinate of ROI's axis aligned bounding box extremum point #8
EXTREMA_P8_Y  
POLYGONALITY_AVE The score ranges from $ -infty $ to 10. Score 10 indicates the object shape is polygon and score $ -infty $ indicates the ROI shape is not polygon
HEXAGONALITY_AVE The score ranges from $ -infty $ to 10. Score 10 indicates the object shape is hexagon and score $ -infty $ indicates the ROI shape is not hexagon
HEXAGONALITY_STDDEV Standard deviation of hexagonality_score relative to its mean
DIAMETER_MIN_ENCLOSING_CIRCLE Diameter of the minimum enclosing circle
DIAMETER_CIRCUMSCRIBING_CIRCLE Diameter of the circumscribing circle
DIAMETER_INSCRIBING_CIRCLE Diameter of inscribing circle
GEODETIC_LENGTH Geodetic length approximated by a rectangle with the same area and perimeter: $ area = geodeticlength * thickness$; $perimeter = 2 * (geodetic_length + thickness) $
THICKNESS Thickness approximated by a rectangle with the same area and perimeter: $ area = geodeticlength * thickness$; $perimeter = 2 * (geodetic_length + thickness) $
ROI_RADIUS_MEAN Mean centroid to edge distance
ROI_RADIUS_MAX Maximum of centroid to edge distances
ROI_RADIUS_MEDIAN Median value of centroid to edge distances

Texture features:


Nyxus feature code Description
GLCM_ASM GLCM, Angular second moment, IBSI # 8ZQL
GLCM_ACOR GLCM, Autocorrelation, IBSI # QWB0
GLCM_CLUPROM GLCM, Cluster prominence, IBSI # AE86
GLCM_CLUSHADE GLCM, Cluster shade, IBSI # 7NFM
GLCM_CLUTEND GLCM, Cluster tendency, IBSI # DG8W
GLCM_CONTRAST GLCM, Contrast, IBSI # ACUI
GLCM_CORRELATION GLCM, Correlation, IBSI # NI2N
GLCM_DIFAVE GLCM, Difference average, IBSI # TF7R
GLCM_DIFENTRO GLCM, Difference entropy, IBSI # NTRS
GLCM_DIFVAR GLCM, Difference variance, IBSI # D3YU
GLCM_DIS GLCM, Dissimilarity, IBSI # 8S9J
GLCM_ENERGY GLCM, Energy
GLCM_ENTROPY GLCM, Entropy
GLCM_HOM1 GLCM, Homogeneity-1
GLCM_HOM2 GLCM, Homogeneity-2
GLCM_ID GLCM, Inverse difference, IBSI # IB1Z
GLCM_IDN GLCM, Inverse difference normalized, IBSI # NDRX
GLCM_IDM GLCM, Inverse difference moment, IBSI # WF0Z
GLCM_IDMN GLCM, Inverse difference moment normalized, IBSI # 1QCO
GLCM_INFOMEAS1 GLCM, Information measure of correlation 1, IBSI # R8DG
GLCM_INFOMEAS2 GLCM, Information measure of correlation 2, IBSI # JN9H
GLCM_IV GLCM, Inverse variance, IBSI # E8JP
GLCM_JAVE GLCM, Joint average, IBSI # 60VM
GLCM_JE GLCM, Joint entropy, IBSI # TU9B
GLCM_JMAX GLCM, Joint maximum (aka max probability), IBSI # GYBY
GLCM_JVAR GLCM, Joint variance (aka sum of squares), IBSI # UR99
GLCM_SUMAVERAGE GLCM, Sum average, IBSI # ZGXS
GLCM_SUMENTROPY GLCM, Sum entropy, IBSI # P6QZ
GLCM_SUMVARIANCE GLCM, Sum variance, IBSI # OEEB
GLCM_VARIANCE GLCM, Variance
GLRLM_SRE Grey level run-length matrix (GLRLM) based feature, Short Run Emphasis
GLRLM_LRE GLRLM, Long Run Emphasis
GLRLM_GLN GLRLM, Grey Level Non-Uniformity
GLRLM_GLNN GLRLM, Grey Level Non-Uniformity Normalized
GLRLM_RLN GLRLM, Run Length Non-Uniformity
GLRLM_RLNN GLRLM, Run Length Non-Uniformity Normalized
GLRLM_RP GLRLM, Run Percentage
GLRLM_GLV GLRLM, Grey Level Variance
GLRLM_RV GLRLM, Run Variance
GLRLM_RE GLRLM, Run Entropy
GLRLM_LGLRE GLRLM, Low Grey Level Run Emphasis
GLRLM_HGLRE GLRLM, High Grey Level Run Emphasis
GLRLM_SRLGLE GLRLM, Short Run Low Grey Level Emphasis
GLRLM_SRHGLE GLRLM, Short Run High Grey Level Emphasis
GLRLM_LRLGLE GLRLM, Long Run Low Grey Level Emphasis
GLRLM_LRHGLE GLRLM, Long Run High Grey Level Emphasis
GLDZM_SDE GLDZM, Small Distance Emphasis
GLDZM_LDE GLDZM, Large Distance Emphasis
GLDZM_LGLE GLDZM, Low Grey Level Emphasis
GLDZM_HGLE GLDZM, High GreyLevel Emphasis
GLDZM_SDLGLE GLDZM, Small Distance Low Grey Level Emphasis
GLDZM_SDHGLE GLDZM, Small Distance High GreyLevel Emphasis
GLDZM_LDLGLE GLDZM, Large Distance Low Grey Level Emphasis
GLDZM_LDHGLE GLDZM, Large Distance High Grey Level Emphasis
GLDZM_GLNU GLDZM, Grey Level Non Uniformity
GLDZM_GLNUN GLDZM, Grey Level Non Uniformity Normalized
GLDZM_ZDNU GLDZM, Zone Distance Non Uniformity
GLDZM_ZDNUN GLDZM, Zone Distance Non Uniformity Normalized
GLDZM_ZP GLDZM, Zone Percentage
GLDZM_GLM GLDZM, Grey Level Mean
GLDZM_GLV GLDZM, Grey Level Variance
GLDZM_ZDM GLDZM, Zone Distance Mean
GLDZM_ZDV GLDZM, Zone Distance Variance
GLDZM_ZDE GLDZM, Zone Distance Entropy
GLSZM_SAE GLDZM, Grey level size zone matrix (GLSZM) based feature, Small Area Emphasis
GLSZM_LAE Large Area Emphasis
GLSZM_GLN Grey Level Non - Uniformity
GLSZM_GLNN Grey Level Non - Uniformity Normalized
GLSZM_SZN Size - Zone Non - Uniformity
GLSZM_SZNN Size - Zone Non - Uniformity Normalized
GLSZM_ZP Zone Percentage
GLSZM_GLV Grey Level Variance
GLSZM_ZV Zone Variance
GLSZM_ZE Zone Entropy
GLSZM_LGLZE Low Grey Level Zone Emphasis
GLSZM_HGLZE High Grey Level Zone Emphasis
GLSZM_SALGLE Small Area Low Grey Level Emphasis
GLSZM_SAHGLE Small Area High Grey Level Emphasis
GLSZM_LALGLE Large Area Low Grey Level Emphasis
GLSZM_LAHGLE Large Area High Grey Level Emphasis
GLDM_SDE Grey level dependency matrix (GLDM) based feature, Small Dependence Emphasis(SDE)
GLDM_LDE Large Dependence Emphasis (LDE)
GLDM_GLN Grey Level Non-Uniformity (GLN)
GLDM_DN Dependence Non-Uniformity (DN)
GLDM_DNN Dependence Non-Uniformity Normalized (DNN)
GLDM_GLV Grey Level Variance (GLV)
GLDM_DV Dependence Variance (DV)
GLDM_DE Dependence Entropy (DE)
GLDM_LGLE Low Grey Level Emphasis (LGLE)
GLDM_HGLE High Grey Level Emphasis (HGLE)
GLDM_SDLGLE Small Dependence Low Grey Level Emphasis (SDLGLE)
GLDM_SDHGLE Small Dependence High Grey Level Emphasis (SDHGLE)
GLDM_LDLGLE Large Dependence Low Grey Level Emphasis (LDLGLE)
GLDM_LDHGLE Large Dependence High Grey Level Emphasis (LDHGLE)
NGLDM_LDE Low Dependence Emphasis
NGLDM_HDE High Dependence Emphasis
NGLDM_LGLCE Low Grey Level Count Emphasis
NGLDM_HGLCE High Grey Level Count Emphasis
NGLDM_LDLGLE Low Dependence Low Grey Level Emphasis
NGLDM_LDHGLE Low Dependence High Grey Level Emphasis
NGLDM_HDLGLE High Dependence Low Grey Level Emphasis
NGLDM_HDHGLE High Dependence High Grey Level Emphasis
NGLDM_GLNU Grey Level Non-Uniformity
NGLDM_GLNUN Grey Level Non-Uniformity Normalised
NGLDM_DCNU Dependence Count Non-Uniformity
NGLDM_DCNUN Dependence Count Non-Uniformity Normalised
NGLDM_GLM Grey Level Mean
NGLDM_GLV Grey Level Variance
NGLDM_DCM Dependence Count Mean
NGLDM_DCV Dependence Count Variance
NGLDM_DCE Dependence Count Entropy
NGLDM_DCENE Dependence Count Energy
NGTDM_COARSENESS Neighbouring Grey Tone Difference Matrix (NGTDM) Features, Coarseness
NGTDM_CONTRAST NGTDM, Contrast
NGTDM_BUSYNESS NGTDM, Busyness
NGTDM_COMPLEXITY NGTDM, Complexity
NGTDM_STRENGTH NGTDM, Strength

Radial intensity distribution features:


Nyxus feature code Description
ZERNIKE2D Zernike features
FRAC_AT_D Fraction of total intensity at a given radius
MEAN_FRAC Mean fractional intensity at a given radius
RADIAL_CV Coefficient of variation of intensity within a ring (band), calculated across $n$ slices

Frequency and orientational features:


Nyxus feature code Description
GABOR A set of Gabor filters of varying frequencies and orientations

2D image moments:


Nyxus feature code Description
SPAT_MOMENT_00 Spatial (raw) moments
SPAT_MOMENT_01 of order 00, 01, 02, etc
SPAT_MOMENT_02  
SPAT_MOMENT_03  
SPAT_MOMENT_10  
SPAT_MOMENT_11  
SPAT_MOMENT_12  
SPAT_MOMENT_20  
SPAT_MOMENT_21  
SPAT_MOMENT_30  
WEIGHTED_SPAT_MOMENT_00 Spatial moments weighted by pixel distance to ROI edge
WEIGHTED_SPAT_MOMENT_01  
WEIGHTED_SPAT_MOMENT_02  
WEIGHTED_SPAT_MOMENT_03  
WEIGHTED_SPAT_MOMENT_10  
WEIGHTED_SPAT_MOMENT_11  
WEIGHTED_SPAT_MOMENT_12  
WEIGHTED_SPAT_MOMENT_20  
WEIGHTED_SPAT_MOMENT_21  
WEIGHTED_SPAT_MOMENT_30  
CENTRAL_MOMENT_02 Central moments
CENTRAL_MOMENT_03  
CENTRAL_MOMENT_11  
CENTRAL_MOMENT_12  
CENTRAL_MOMENT_20  
CENTRAL_MOMENT_21  
CENTRAL_MOMENT_30  
WEIGHTED_CENTRAL_MOMENT_02 Central moments weighted by pixel distance to ROI edge
WEIGHTED_CENTRAL_MOMENT_03  
WEIGHTED_CENTRAL_MOMENT_11  
WEIGHTED_CENTRAL_MOMENT_12  
WEIGHTED_CENTRAL_MOMENT_20  
WEIGHTED_CENTRAL_MOMENT_21  
WEIGHTED_CENTRAL_MOMENT_30  
NORM_CENTRAL_MOMENT_02 Normalized central moments
NORM_CENTRAL_MOMENT_03  
NORM_CENTRAL_MOMENT_11  
NORM_CENTRAL_MOMENT_12  
NORM_CENTRAL_MOMENT_20  
NORM_CENTRAL_MOMENT_21  
NORM_CENTRAL_MOMENT_30  
NORM_SPAT_MOMENT_00 Normalized (standardized) spatial moments
NORM_SPAT_MOMENT_01  
NORM_SPAT_MOMENT_02  
NORM_SPAT_MOMENT_03  
NORM_SPAT_MOMENT_10  
NORM_SPAT_MOMENT_20  
NORM_SPAT_MOMENT_30  
HU_M1 Hu's moment 1
HU_M2 Hu's moment 2
HU_M3 Hu's moment 3
HU_M4 Hu's moment 4
HU_M5 Hu's moment 5
HU_M6 Hu's moment 6
HU_M7 Hu's moment 7
WEIGHTED_HU_M1 Weighted Hu's moment 1
WEIGHTED_HU_M2 Weighted Hu's moment 2
WEIGHTED_HU_M3 Weighted Hu's moment 3
WEIGHTED_HU_M4 Weighted Hu's moment 4
WEIGHTED_HU_M5 Weighted Hu's moment 5
WEIGHTED_HU_M6 Weighted Hu's moment 6
WEIGHTED_HU_M7 Weighted Hu's moment 7

Neighbor features:


Nyxus feature code Description
NUM_NEIGHBORS The number of neighbors bordering the ROI's perimeter within proximity radius specified by command line argument --pixelDistance. (Default value of --pixelDistance is 5.) Algorithmically calculating this feature invilves solving the nearest neighbors search problem that in turn involves the proximity measure and the proximity threshold. Particularly, this plugin uses the L_2 norm measure over Cartesian space of pixel coordinates and parameter --pixelDistance
PERCENT_TOUCHING Percent of ROI's contour pixels located at distance 0 from neighboring other ROIs's contour
CLOSEST_NEIGHBOR1_DIST Distance in pixels from ROI's centroid to the nearest neighboring ROI's centroid
CLOSEST_NEIGHBOR1_ANG Angle in degrees between ROI's centroid and its nearest neighboring ROI's centroid
CLOSEST_NEIGHBOR2_DIST Distance in pixels from ROI's centroid to the second nearest neighboring ROI's centroid
CLOSEST_NEIGHBOR2_ANG Angle in degrees between ROI's centroid and its second nearest neighboring ROI's centroid
ANG_BW_NEIGHBORS_MEAN Mean angle in degrees between ROI's centroid and centroids of its neighboring ROIs
ANG_BW_NEIGHBORS_STDDEV Standard deviation in degrees of angles between ROI's centroid and centroids of its neighboring ROIs
ANG_BW_NEIGHBORS_MODE Mode value in degrees of angles between ROI's centroid and centroids of its neighboring ROIs