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DESCRIPTION
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Type: Package
Package: BatchQC
Title: Batch Effects Quality Control Software
Version: 2.2.2
Date: 2024-10-11
Authors@R: c(
person("Jessica", "Anderson", , "[email protected]",
role = c("aut", "cre"), comment = c(ORCID = "0000-0002-0542-9872")),
person("W. Evan", "Johnson", , "[email protected]", role = c("aut"),
comment = c(ORCID = "0000-0002-6247-6595")),
person("Solaiappan", "Manimaran", , "[email protected]", role = "aut"),
person("Heather", "Selby", , "[email protected]", role = "ctb"),
person("Claire", "Ruberman", , "[email protected]", role = "ctb"),
person("Kwame", "Okrah", , "[email protected]", role = "ctb"),
person("Hector Corrada", "Bravo", , "[email protected]", role = "ctb"),
person("Michael", "Silverstein", , "[email protected]", role = "ctb"),
person("Regan", "Conrad", , "[email protected]", role = "ctb"),
person("Zhaorong", "Li", , "[email protected]", role = "ctb"),
person("Evan", "Holmes", , "[email protected]", role = "aut"),
person("Solomon", "Joseph", , "[email protected]", role = "ctb")
)
Description: Sequencing and microarray samples often are collected or
processed in multiple batches or at different times. This often
produces technical biases that can lead to incorrect results in the
downstream analysis. BatchQC is a software tool that streamlines batch
preprocessing and evaluation by providing interactive diagnostics,
visualizations, and statistical analyses to explore the extent to
which batch variation impacts the data. BatchQC diagnostics help
determine whether batch adjustment needs to be done, and how
correction should be applied before proceeding with a downstream
analysis. Moreover, BatchQC interactively applies multiple common
batch effect approaches to the data and the user can quickly see the
benefits of each method. BatchQC is developed as a Shiny App. The
output is organized into multiple tabs and each tab features an
important part of the batch effect analysis and visualization of the
data. The BatchQC interface has the following analysis groups:
Summary, Differential Expression, Median Correlations, Heatmaps,
Circular Dendrogram, PCA Analysis, Shape, ComBat and SVA.
License: MIT + file LICENSE
URL: https://github.com/wejlab/BatchQC
BugReports: https://github.com/wejlab/BatchQC/issues
Depends:
R (>= 4.4.0)
Imports:
data.table,
DESeq2,
dplyr,
EBSeq,
ggdendro,
ggnewscale,
ggplot2,
limma,
matrixStats,
pheatmap,
RColorBrewer,
reader,
reshape2,
scran,
shiny,
shinyjs,
shinythemes,
stats,
SummarizedExperiment,
sva,
S4Vectors,
tibble,
tidyr,
tidyverse,
utils
Suggests:
BiocManager,
BiocStyle,
bladderbatch,
devtools,
knitr,
lintr,
plotly,
rmarkdown,
spelling,
testthat (>= 3.0.0)
VignetteBuilder:
knitr
biocViews: BatchEffect, GraphAndNetwork, Microarray, Normalization, PrincipalComponent,
Sequencing, Software, Visualization, QualityControl, RNASeq,
Preprocessing, DifferentialExpression, ImmunoOncology
Config/testthat/edition: 3
Encoding: UTF-8
Language: en-US
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2