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Healthy Patients' Structural Image Dataset

This repository contains code for maintenance of a dataset containing research quality T1 MRI images (e.g., resolution of 1mm isotropic or below) of healthy controls (no history of neurological disorder) scanned at the University of Pennsylvania (N=868).

The impetus of this project was to create a cortical thickness template including subjects across the entire age spectrum for calculating "neuroprint" heatmaps that illustrate an individual's age-adjusted atrophy. The repository for that initiative can be found here.

The data were gathered into a Flywheel Collection and visually inspected for motion and other artifacts.

Visualization of the age distribution:

Age distribution

Breakdown of contributions by group, calculated using code/accounting.ipynb:

Group Age (mean) Age (sd) % Female N
Connectome 28.190698623657227 8.111772537231445 41.86046511627907 43
Penn FTD Center 39.57398986816406 19.1475887298584 56.82326621923938 447
Davis Group 32.681251525878906 11.379103660583496 56.25 16
David Wolk Lab 68.16585540771484 15.615558624267578 64.8780487804878 205
Detre Group 28.669353485107422 5.744270324707031 53.2258064516129 62
Oathes Lab 30.515789031982422 10.496979713439941 56.84210526315789 95