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DESCRIPTION
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DESCRIPTION
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Package: SampleQC
Title: Robust, multivariate, multi-sample, multi-celltype QC for single cell RNA-seq data
Version: 0.6.6
Authors@R:
person(given = "Will",
family = "Macnair",
email = "[email protected]",
role = c("aut", "cre"),
comment = c(ORCID = "0000-0001-6357-0834"))
Description: `SampleQC` is an R package for robust multivariate, multi-
celltype, multi-sample quality control for single cell RNA-seq. Unimodal
approaches to QC, such as `scater`, may preferentially remove healthy cells
from celltypes with extreme QC statistics, introducing bias. `SampleQC`
removes this bias by fitting a Gaussian mixture model. The fit is done
across multiple celltypes simultaneously, and using robust estimators
allows it to find the distributions in the (expected) presence of outliers.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
Imports:
assertthat,
BiocStyle,
BiocParallel,
data.table,
forcats,
ggplot2,
gtools,
igraph,
magrittr,
MASS,
Matrix,
matrixStats,
mclust,
mixtools,
mvnfast,
mvtnorm,
parallel,
patchwork,
RColorBrewer,
Rcpp,
RcppArmadillo,
RcppDist,
rmarkdown,
S4Vectors,
scales,
SingleCellExperiment,
stringr,
SummarizedExperiment,
uwot
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.1.2
Suggests:
testthat (>= 2.1.0),
knitr
LinkingTo:
Rcpp,
RcppDist,
RcppArmadillo
VignetteBuilder: knitr