DESCRIPTION

Package: TWASKnockoff
Type: Package
Title: A Knockoff-based Framework for Causal Genes Identifications
Version: 0.1.0
Authors@R: c(
    person("Xiangyu", "Zhang", email = "xiangyu.zhang@yale.edu", role = c("aut", "cre")),
    person("Lijun", "Wang", email = "lijun.wang@yale.edu", role = c("aut", "ctb")))
Description: 
    A new knockoff-based framework designed to identify causal genes for the trait of interest using GWAS summary statistics and gene expression-mapping data. TWASKnockoff extends the knockoff inference to identify disease-causing genes. Unlike the marginal testing performed in traditional TWAS methods, TWASKnockoff examines the conditional independence for each gene-trait pair, considering both correlations in cis-predicted expression across genes and correlations between gene expression levels and genotypes of genetic variants.
License: GPL (>= 3)
Encoding: UTF-8
LazyData: true
URL: https://github.com/zxy0912/TWASKnockoff
BugReports: https://github.com/zxy0912/TWASKnockoff/issues
Suggest:
    rmarkdown
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
Imports:
    glmnet,
    ghostbasil,
    GhostKnockoff,
    susieR,
    Matrix
Remotes: szcf-weiya/ghostbasil, Matrix@1.6-5
Depends: 
    R (>= 2.10)
Suggests: 
    knitr,
    rmarkdown
VignetteBuilder: knitr