AVENGEME is a package for the analysis of the polygenic scoring method. A Shiny interface is provided.
To install within R, devtools::install_github("DudbridgeLab/avengeme").
To run the Shiny interface, avengeme::avengemeShiny().
Dudbridge F (2013) Power and predictive accuracy of polygenic risk scores. PLoS Genet 9:e1003348
Palla L and Dudbridge F (2015) A fast method using polygenic scores to estimate the variance explained by genome-wide marker panels and the proportion of variants affecting a trait. Am J Hum Genet 97:250-259
Dudbridge F, Pashayan N, Yang J (2017) Predictive accuracy of combined genetic and non-genetic risk scores. Genet Epidemiol in press