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v1.5.0
MAJOR refactor/overhaul of all the internal classes. This was necessary to fully support the mouse array.
new SigSet class object that mirror's sesame's SigSet and SigDF object.
Combines idats, manifest, and sample sheet into one object that is inherited by SampleDataContainer
RawDataset, MethylationDataset, ProbeSubtype all deprecated and replaced by SigSet
SampleDataContainer class is now basically the SigSet plus all pipeline processing settings
new mouse manifest covers all probes and matches sesame's output
Processing will work even if a batch of IDATs have differing probe counts for same array_type, though those
differing probes in question may not be saved.
unit tests confirm that methylprep, sesame, and minfi beta values output match to within 1% of each other now. Note that the intermediate stages of processing (after NOOB and after DYE) do not match
with sesame in this version. Can be +/- 100 intensity units, likely due to differences in order of
steps and/or oob/mask probes used.