Kidney Epigenomic Atlas

This repository hosts the code from The chromatin landscape of healthy and injured cell types in the human kidney. We aim to unravel the molecular underpinnings of kidney diseases and build knowledge to create targeted therapies in the future. Our work maps gene activation and repression in kidney cells across various states - healthy, injured, or repairing."

An effort from many researchers:

Debora L. Gisch¹* , Michelle Brennan²* , Blue B. Lake⁴* , Jeannine Basta³* , Mark S. Keller⁵, Ricardo Melo Ferreira¹, Shreeram Akilesh⁶, Reetika Ghag³, Charles Lu³, Ying-Hua Cheng¹, Kimberly S. Collins¹, Samir V. Parikh⁷, Brad H. Rovin⁷, Lynn Robbins⁸, Lisa Stout³, Kimberly Y. Conklin⁴, Dinh Diep⁴, Bo Zhang³, Amanda Knoten³, Daria Barwinska¹, Mahla Asghari¹, Angela R. Sabo¹, Michael J. Ferkowicz¹, Timothy A Sutton¹, Katherine J Kelly¹, Ian H. De Boer⁶, Sylvia E. Rosas⁹, Krzysztof Kiryluk¹⁰, Jeffrey B. Hodgin¹¹, Fadhl Alakwaa¹¹, Seth Winfree¹², Nichole Jefferson¹³, Aydın Türkmen¹⁴, Joseph P. Gaut³, Nils Gehlenborg⁵, Carrie L. Phillips¹, Tarek M. El-Achkar¹, Pierre C. Dagher¹, Takashi Hato¹, Kun Zhang⁴, Jonathan Himmelfarb⁶, Matthias Kretzler¹¹, Shamim Mollah³, the Kidney Precision Medicine Project (KPMP), Sanjay Jain³# , Michael Rauchman³# , Michael T. Eadon¹#

*= co-first authors contributed equally

1. Indiana University School of Medicine, Indianapolis, IN, 46202, USA
2. Saint Louis University, St. Louis, MO 63103, USA
3. Washington University in Saint Louis, St. Louis, MO 63103, USA
4. Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA Present address: San Diego Institute of Science, Altos Labs, San Diego, CA, USA
5. Harvard Medical School, Boston, MA 02142, USA
6. University of Washington – Seattle, WA 98195, USA
7. Ohio State University Wexner Medical Center, Columbus, OH 43210, USA
8. St. Louis Veteran Affairs Medical Center, St. Louis, MO 63106, USA
9. Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA
10. Columbia University, New York, NY 10032, USA
11. University of Michigan, Ann Arbor, MI 48109, USA
12. University of Nebraska Medical Center, Omaha, NE 68198, USA
13. Kidney Precision Medicine Project Community Engagement Committee, Dallas TX, USA
14. Istanbul School of Medicine, Division of Nephrology, Istanbul, Turkey

Led by Eadon's Lab and support by two consortia KPMP and huBMAP.