pyassconst / bindfit

Determination of association/binding constants from titration data using any system of equilibria

Functionality

1. Numerical simulation of equilibrium concentrations from a set of initial concentrations and a system of equilibria, given the equilibrium constants
2. Calculation of binding curves from the equilibrium concentrations, given a matrix of epsilon values
3. Fitting of calculated binding curves to experimental binding curves, given initial guesses of epsilon and equilibrium constants

Full description

A full description is given in the Jupyter notebook, since it can render maths.

A description of the mathematics used in setting up the system of equilibria, and solving for the equilibrium concentrations, check background.pdf.

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