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Add disambiguate tool to QC portion of the weave pipeline #33
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skchronicles
approved these changes
Jan 12, 2024
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If you can address some of the comments outlined within the next PR, that would be perfect!
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Thanks for the updates!
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Partially addresses #25
This pull request implements disambiguate when a command line user identifies a valid host genome using the --host[-t] and pathogen genome by the --pathogen[-p] flags. If does not use a valid fasta, or gzipped fasta, genome an error will be raised.
Currently this implementation of disambiguate only uses
bwa mem
for alignment. This will need to change in the future including a method of detecting whether a cohort is DNA [bwa mem or support bowtie2] or RNA [STAR-aligner].