-
Notifications
You must be signed in to change notification settings - Fork 0
Commit
This commit does not belong to any branch on this repository, and may belong to a fork outside of the repository.
- Loading branch information
Showing
1 changed file
with
46 additions
and
2 deletions.
There are no files selected for viewing
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Original file line number | Diff line number | Diff line change |
---|---|---|
@@ -1,2 +1,46 @@ | ||
# mpld | ||
A database of Mitochondrial Proteins Linked with Diseases | ||
# mitoPADdb | ||
A database of Mitochondrial Proteins Associated with Diseases | ||
|
||
The mitoPADdb is a manually curated database that provides comprehensive information on *813 mitochondrial | ||
protein-encoding (MPE) genes* associated with *1793 disease terms*. It contains information on mutations | ||
and expressional variations of MPE genes at both the mRNA and protein levels. The database classifies the | ||
diseases linked with mitochondrial proteins into *14 broad categories*. | ||
|
||
## About mitoPADdb | ||
mitoPADdb is available at: [http://bicresources.jcbose.ac.in/ssaha4/mitopaddb](http://bicresources.jcbose.ac.in/ssaha4/mitopaddb). | ||
|
||
The data statistics of mitoPADdb is available in the [Statistics](http://bicresources.jcbose.ac.in/ssaha4/mitopaddb/statistics.html) | ||
page. Please refer to the [Help](http://bicresources.jcbose.ac.in/ssaha4/mitopaddb/help.html) page for | ||
understanding the data and usage of mitoPADdb. It allows users to access the data using two ways - | ||
|
||
1. **Search option**: The search option allows the users top search the database with Gene symbol, UniProt | ||
accession, or both. | ||
|
||
The search option provides information about *18356 mutations*, *1286 expressional variations* (mRNA | ||
and protein levels) with experimental samples and techniques, and associated diseases with source | ||
identifiers. | ||
|
||
3. **Browse options**: The browse options allow users to access these data along with disease-gene-pathway | ||
links and differential genes’ expression heatmap across *317 disease studies*, in following ways. | ||
|
||
* Gene symbol | ||
* Pathway name | ||
* Disease category name | ||
* Disease category-wise MPE gene expression heatmap | ||
* Disease category-pairwise comparison of MPE gene expression heatmap | ||
|
||
## Team | ||
* **Jagannath Das** *([[email protected]](mailto:[email protected]))*<br/> | ||
Senior Research Fellow,<br/> | ||
Department of Biological Sciences,<br/> | ||
Bose Institute, Kolkata, India.<br/> | ||
* **Sudipto Bhattacharjee** *([[email protected]](mailto:[email protected]))*<br/> | ||
Ph.D. Scholar,<br/> | ||
Department of Computer Science and Engineering,<br/> | ||
University of Calcutta, Kolkata, India.<br/> | ||
* **Dr. Sudipto Saha** *([[email protected]](mailto:[email protected]))*<br/> | ||
Associate Professor,<br/> | ||
Department of Biological Sciences,<br/> | ||
Bose Institute, Kolkata, India. | ||
|
||
*Please contact Dr. Sudipto Saha regarding any further queries.* |