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UDS 3 VS UDS 4

Smith Thay edited this page Jun 14, 2024 · 17 revisions

A1

  • More options for ethnicity and race, gender Identity, sexual orientation
  • Sections asses for US Armed Forces, memory, ADI (Area Deprivation Index), and Occupation
Variables that Remained the Same Variables Added in UDSv4 Variables Deleted from UDSv3
BIRTHMO CHLDHDCTRY REASON
BIRTHYR RACEWHITE LEARNED
SEX ETHGERMAN PRESTAT
HANDED ETHIRISH PRESPART
EDUC ETHENGLISH HISPANIC
MARISTAT ETHITALIAN HISPOR
LIVSITUA ETHPOLISH HISPORX
RESIDENC ETHFRENCH RACE
ZIP ETHWHIOTH RACEX
SOURCENW ETHWHIOTHX RACESEC
REFERSC ETHISPANIC RACESECX
ETHMEXICAN RACETER
ETHPUERTO RACETERX
ETHCUBAN PRIMLANG
ETHSALVA PRIMLANX
ETHDOMIN INDEPEND
ETHCOLOM
ETHHISOTH
ETHHISOTHX
RACEBLACK
ETHAFAMER
ETHJAMAICA
ETHHAITIAN
ETHNIGERIA
ETHETHIOP
ETHSOMALI
ETHBLKOTH
ETHBLKOTHX
RACEASIAN
ETHCHINESE
ETHFILIP
ETHINDIA
ETHVIETNAM
ETHKOREAN
ETHJAPAN
ETHASNOTH
ETHASNOTHX
RACEAIAN
RACEAIANX
RACEMENA
ETHLEBANON
ETHIRAN
ETHEGYPT
ETHSYRIA
ETHMOROCCO
ETHISRAEL
ETHMENAOTH
ETHMENAOTX
RACENHPI
ETHHAWAII
ETHSAMOAN
ETHCHAMOR
ETHTONGAN
ETHFIJIAN
ETHMARSHAL
ETHNHPIOTH
ETHNHPIOTX
RACEUNKN
GENMAN
GENWOMAN
GENTRMAN
GENTRWOMAN
GENNONBI
GENTWOSPIR
GENOTH
GENOTHX
GENDKN
GENNOANS
BIRTHSEX
INTERSEX
SEXORNGAY
SEXORNHET
SEXORNBI
SEXORNTWOS
SEXORNOTH
SEXORNOTHX
SEXORNDNK
SEXORNNOAN
PREDOMLAN
PREDOMLANX
LVLEDUC
SERVED
MEDVA
EXRTIME
MEMWORS
MEMTROUB
MEMTEN
ADISTATE
ADINAT
PRIOCC
REFERSCX
REFLEARNED
REFCTRSOCX
REFCTRREGX
REFOTHWEBX
REFOTHMEDX
REFOTHREGX
REFOTHX

A1a

  • entirely new form used to help understand how certain experiences affect health
  • Section on transportation, financial security,Social connections, activities, and environment
  • Experiences with the healthcare system, Experiences of Discrimination
New Variables
OWNSCAR
TRSPACCESS
TRANSPROB
TRANSWORRY
TRSPLONGER
TRSPMED
INCOMEYR
FINSATIS
BILLPAY
FINUPSET
EATLESS
EATLESSYR
LESSMEDS
LESSMEDSYR
COMPCOMM
COMPUSA
FAMCOMP
GUARDEDU
GUARDREL
GUARDRELX
GUARD2EDU
GUARD2REL
GUARD2RELX
EMPTINESS
MISSPEOPLE
FRIENDS
ABANDONED
CLOSEFRND
PARENTCOMM
CHILDCOMM
FRIENDCOMM
PARTICIPATE
SAFEHOME
SAFECOMM
DELAYMED
SCRIPTPROB
MISSEDFUP
DOCADVICE
HEALTHACC
LESSCOURT
POORSERV
NOTSMART
ACTAFRAID
THREATENED
POORMEDTRT
EXPANCEST
EXPGENDER
EXPRACE
EXPAGE
EXPRELIG
EXPHEIGHT
EXPWEIGHT
EXPAPPEAR
EXPSEXORN
EXPEDUCINC
EXPDISAB
EXPSKIN
EXPOTHER
EXPNOTAPP
EXPNOANS
EXPSTRS

A2

  • The UDS3-A2 form primarily focuses on the co-participant's demographics, including birth month and year, sex, ethnicity, race, education level, and relationship to the subject. It also inquires about how long the co-participant has known the subject, living arrangements, and the frequency of in-person and telephone contact.
  • In contrast, the UDS4-A2 form emphasizes the co-participant's assessment of the participant's memory and cognitive health. It includes questions about the relationship duration, living arrangements, frequency and duration of contact, and the co-participant’s reliability. Moreover, it asks about the co-participant's perception of the participant's memory, frequency of memory issues, and a comparative assessment of the participant's memory compared to 10 years ago.
  • These differences highlight a shift from gathering basic demographic data in UDS3 to a more focused evaluation of the participant's cognitive health from the perspective of someone close to them in UDS4.
Variables that Remained the Same Variables Added in UDS 4 Variables Deleted from UDS 4
INRELTO INCNTMOD INBIRMO
INKNOWN INCNTMDX INBIRYR
INLIVWTH INCNTFRQ INSEX
INRELY INCNTTIM INHISP
INMEMWORS INHISPOR
INMEMTROUB INHISPOX
INMEMTEN INRACE
INRACEX
INRASEC
INRASECX
INRATER
INRATERX
INEDUC
INVISITS
INCALLS

A3

  • UDS4 Form A3 has a similar structure but includes updates and modifications in the diagnostic categories and evaluation methods. It also emphasizes detailed diagnostic information and may incorporate updated medical and psychiatric terminologies or criteria reflecting advancements in the understanding of neurological conditions.
  • Only sections for Biological parents, Full siblings, and Biological children remain

A4

  • Now split into A4 Participant Medication and A4a Ad-Specific Drug Treatment
  • A4 has predominantly remained the same with the exception of using RXNorm code instead of DrugID and the addition and deletion of a few medications.
Options Added Options Removed
Medication: apixaban Medication: conjugate estrogens
Medication: citalopram Medication: digoxin
Medication: diclofenac OTC: psyllium
Medication: sildenafil OTC: pyroxidine
OTC: biotin
OTC: turmeric

A4a

  • Entirely new form
  • This form is to be used to record treatments known to significantly impact Alzheimer disease and related dementias (ADRD) biomarkers, whether received as part of clinical care or a clinical trial
New Variables
TRTBIOMARK
TARGETAB1
TARGETTAU1
TARGETINF1
TARGETSYN1
TARGETOTH1
TARGETOTX1
TRTTRIAL1
NCTNUM1
STARTMO1
STARTYEAR1
ENDMO1
ENDYEAR1
CARETRIAL1
TRIALGRP1
TARGETAB2
TARGETTAU2
TARGETINF2
TARGETSYN2
TARGETOTH2
TARGETOTX2
TRTTRIAL2
NCTNUM2
STARTMO2
STARTYEAR2
ENDMO2
ENDYEAR2
CARETRIAL2
TRIALGRP2
TARGETAB3
TARGETTAU3
TARGETINF3
TARGETSYN3
TARGETOTH3
TARGETOTX3
TRTTRIAL3
NCTNUM3
STARTMO3
STARTYEAR3
ENDMO3
ENDYEAR3
CARETRIAL3
TRIALGRP3
TARGETAB4
TARGETTAU4
TARGETINF4
TARGETSYN4
TARGETOTH4
TARGETOTX4
TRTTRIAL4
NCTNUM4
STARTMO4
STARTYEAR4
ENDMO4
ENDYEAR4
CARETRIAL4
TRIALGRP4
TARGETAB5
TARGETTAU5
TARGETINF5
TARGETSYN5
TARGETOTH5
TARGETOTX5
TRTTRIAL5
NCTNUM5
STARTMO5
STARTYEAR5
ENDMO5
ENDYEAR5
CARETRIAL5
TRIALGRP5
TARGETAB6
TARGETTAU6
TARGETINF6
TARGETSYN6
TARGETOTH6
TARGETOTX6
TRTTRIAL6
NCTNUM6
STARTMO6
STARTYEAR6
ENDMO6
ENDYEAR6
CARETRIAL6
TRIALGRP6
TARGETAB7
TARGETTAU7
TARGETINF7
TARGETSYN7
TARGETOTH7
TARGETOTX7
TRTTRIAL7
NCTNUM7
STARTMO7
STARTYEAR7
ENDMO7
ENDYEAR7
CARETRIAL7
TRIALGRP7
TARGETAB8
TARGETTAU8
TARGETINF8
TARGETSYN8
TARGETOTH8
TARGETOTX8
TRTTRIAL8
NCTNUM8
STARTMO8
STARTYEAR8
ENDMO8
ENDYEAR8
CARETRIAL8
TRIALGRP8
ADVEVENT
ARIAE
ARIAH
ADVERSEOTH
ADVERSEOTX

A5-D2

  • A5 and D2 now share the same form
  • Cigarette smoking section remains the same except questions are ordered differently.
  • Alcohol use: 1 Variable is added and two are modified to account for past 12 months instead of 3
  • Substance use: Questions modified to account for past 12 months and prior t o12 months. Question about alcohol use removed and question about cannabis added.
  • Cardiovascular disease: Age at most recent heart attack changed to year off. Angina removed.
  • Cerebrovascular disease: 3 variable additions, one deletion. Questions modifies for age instead of year.
  • Neurologic conditions- 17 variable additions. Questions fro Traumatic brain injury modified for head injury
  • Medical conditions: 12 variable additions relating to age, cancer and covid
  • Psychiatric conditions: 5 variable additions mostly related to anxiety.
  • Menstrual and reproductive health: new section, 11 added variables

B1

  • B1 in UDS4 combines B1 and B1a from UDS3
Variables that Remained the Same Variables Added in UDSv4 Variables Deleted from UDSv3
HEIGHT WAIST1 BPSYS
WEIGHT WAIST2 BPDIAS
HRATE HIP1 VISION
HIP2 VISCORR
BPSYSL1 VISWCORR
BPDIASL1 HEARING
BPSYSL2 HEARAID
BPDIASL2 HEARWAID
BPSYSR1
BPDIASR1
BPSYSR2
BPDIASR2

B3

  • New form
New Variables in UDS V4
PDNORMAL
SPEECH
SPEECHX
FACEXP
FACEXPX
TRESTFAC
TRESTFAX
TRESTRHD
TRESTRHX
TRESTLHD
TRESTLHX
TRESTRFT
TRESTRFX
TRESTLFT
TRESTLFX
TRACTRHD
TRACTRHX
TRACTLHD
TRACTLHX
RIGDNECK
RIGDNEX
RIGDUPRT
RIGDUPRX
RIGDUPLF
RIGDUPLX
RIGDLORT
RIGDLORX
RIGDLOLF
RIGDLOLX
TAPSRT
TAPSRTX
TAPSLF
TAPSLFX
HANDMOVR
HANDMVRX
HANDMOVL
HANDMVLX
HANDALTR
HANDATRX
HANDALTL
HANDATLX
LEGRT
LEGRTX
LEGLF
LEGLFX
ARISING
ARISINGX
POSTURE
POSTUREX
GAIT
GAITX
POSSTAB
POSSTABX
BRADYKIN
BRADYKIX
TOTALUPDRS

B4

  • Appears to be unchanged

B5

  • Appears to be unchanged

B6

  • Appears to be unchanged

B7

  • Appears to be unchanged

B8

  • Significant changes were made to this form.
  • Overall structural change with a majority of variables modified, added and removed.

B9

  • Section 1 – Declines in function: 5 variables added
  • Section 2 – Cognitive impairment: 1 variable removed
  • Section 3 – Behavioral changes: 12 additional variables added. More options have been added to questions from UDS3.
  • Section 4 – Motor changes- 5 variable additions, 5 variables removed
  • Section 5 – Overall course of decline and predominant domain: remains the same
  • Levy body disease section removed

C2

Variables Added in UDS 4 (Present in UDS 4 but not in UDS 3):

UDSBENTC UDSBENTD UDSBENRS DIGFORCT DIGFORSL DIGBACCT DIGBACLS MOCAORDT MOCAORMO MOCAORYR MOCAORDY MOCAORPL MOCAORCT REY1REC REY1INT REY2REC REY2INT REY3REC REY3INT REY4REC REY4INT REY5REC REY5INT REYBREC REYBINT REY6REC REY6INT REYDREC REYDINT REYDTI REYMETHOD REYTCOR REYFPOS CERAD1REC CERAD1READ CERAD1INT CERAD2REC CERAD2READ CERAD2INT CERAD3REC CERAD3READ CERAD3INT CERADDTI CERADJ6REC CERADJ6INT CERADJ7YES CERADJ7NO MINTTOTS MINTTOTW MINTSCNG MINTSCNC MINTPCNG MINTPCNC COGSTAT RESPVAL RESPHEAR RESPDIST RESPINTR RESPDISN RESPFATG RESPEMOT RESPASST RESPOTH RESPOTHX

Variables Deleted in UDS 4 (Present in UDS 3 but not in UDS 4):

None

Variables That Remain (Common to Both UDS 3 and UDS 4):

MOCACOMP MOCAREAS MOCALOC MOCALAN MOCALANX MOCAVIS MOCAHEAR MOCATOTS MOCATRAI MOCACUBE MOCACLOC MOCACLON MOCACLOH MOCANAMI MOCAREGI MOCADIGI MOCALETT MOCASER7 MOCAREPE MOCAFLUE MOCAABST MOCARECN MOCARECC MOCARECR UDSVERFC UDSVERFN UDSVERNF UDSVERLC UDSVERLR UDSVERLN UDSVERTN UDSVERTE UDSVERTI NPSYCLOC NPSYLAN NPSYLANX CRAFTVRS CRAFTURS UDSBENTC DIGFORCT DIGFORSL DIGBACCT DIGBACLS ANIMALS VEG TRAILA TRAILARR TRAILALI TRAILB TRAILBRR TRAILBLI COGSTAT

C2T

  • Adds Video-assisted conference and Some combination of the two for modality of communication.
  • Verbal learning test can be either Rey AVLT or CERAD
  • Besides the verbal learning test options both versions share the same sections and are very similar in how they are conducted.
Variables that Remained the Same Variables Added in UDSv4 Variables Deleted from UDSv3
MOCACOMP FRMDATEC2C2T PACKET
MOCAREAS INITIALSC2C2T FORMID
MOCALAN LANGC2C2T FORMVER
MOCALANX MODEC2C2T ADCID
MOCAHEAR RMREASC2C2T PTID
MOCBTOTS RMMODEC2C2T VISITMO
MOCADIGI VERBALTEST VISITDAY
MOCALETT REYBREC VISITYR
MOCASER7 REYBINT VISITNUM
MOCAREPE CERAD1REC INITIALS
MOCAFLUE CERAD1INT MODCOMM
MOCAABST CERAD2REC REYTCOR
MOCARECN CERAD2INT REYFPOS
MOCARECC CERAD3REC DIGFORCT
MOCARECR CERAD3INT DIGFORSL
MOCAORDT CERADDTI DIGBACCT
MOCAORMO CERADJ6REC DIGBACLS
MOCAORYR CERADJ6INT  
MOCAORDY CERADJ7YES  
MOCAORPL CERADJ7NO  
MOCAORCT REYDTI  
NPSYLAN    
NPSYLANX    
CRAFTVRS    
CRAFTURS    
REY1REC    
REY1INT    
REY2REC    
REY2INT    
REY3REC    
REY3INT    
REY4REC    
REY4INT    
REY5REC    
REY5INT    
REY6REC    
REY6INT    
OTRAILA    
OTRLARR    
OTRLALI    
OTRAILB    
OTRLBRR    
OTRLBLI    
CRAFTDVR    
CRAFTDRE    
CRAFTDTI    
CRAFTCUE    
ANIMALS    
VEG    
UDSVERFC    
UDSVERFN    
UDSVERNF    
UDSVERLC    
UDSVERLR    
UDSVERLN    
UDSVERTN    
UDSVERTE    
UDSVERTI    
REYDREC    
REYDINT    
REYTCOR    
REYFPOS    
VNTTOTW    
VNTPCNC    
COGSTAT    
RESPVAL    
RESPHEAR    
RESPDIST    
RESPINTR    
RESPDISN    
RESPFATG    
RESPEMOT    
RESPASST    
RESPOTH    
RESPOTHX    

Z1 will not be included in v4

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