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feat: Update Info in About (#209) #210

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Nov 15, 2023
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feat: Update Info in About (#209) #210

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48 changes: 45 additions & 3 deletions frontend/src/views/AboutView.vue
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Original file line number Diff line number Diff line change
Expand Up @@ -51,9 +51,45 @@ const Acknowledgements: AcknowledgementsType = {
researcher investigating rare diseases, REEV is here to streamline your workflow. Our
platform combines cutting-edge technology with user-friendly interfaces to ensure that
you have the resources you need to make informed decisions.
</p></v-card-text
></v-card
>
</p>
<p class="subtitle">Sequence Variants in REEV</p>
<p class="description">
REEV's documentation on ACMG Sequence Variant Criteria provides a comprehensive guide
for the automated classification of sequence variants. This process emphasizes
transparency for users, ensuring they receive detailed reports of evidence supporting
or contradicting each criterion. It is meticulously designed to inform users why
certain criteria are applied or omitted in specific cases, such as when one criterion
may invalidate others due to the nature of the variant (e.g., BA1 disabling all other
benign criteria). In addition, the ACMG Sequence Variant Details section elaborates on
the implementation of these classification criteria. This includes a detailed
description of the data sources utilized in the classification of sequence variants.
These sources form the foundation of the classification process, aiding in the
accurate and comprehensive evaluation of sequence variants.
</p>
<p class="subtitle">Copy Number Variants in REEV</p>
<p class="description">
The ACMG CNV Criteria section in REEV's documentation outlines the implementation of
criteria for CNVs (Copy Number Variants), based on guidelines from Riggs et al.
(2020). These criteria are critical for understanding and classifying CNVs in the
context of genetic analysis and rare disease research. Furthermore, the ACMG CNV
Details page provides in-depth information about the assessment criteria for CNVs.
This includes an overview of the data used for classification, emphasizing the
thorough and detailed approach REEV takes in evaluating CNVs. The data used in this
classification process is pivotal for understanding the genetic implications of CNVs
and their potential impact on rare genetic disorders.
</p>
<p class="description">
Overall, REEV's approach to both sequence and CNV variants is characterized by a
meticulous and transparent methodology. The platform's use of comprehensive data
sources and adherence to established criteria ensures that it remains a valuable tool
for researchers and clinicians in the field of rare disease genetics.
</p>
<p class="description">
For more detailed information, please visit our
<a href="https://reev.readthedocs.io/en/latest/">documentation</a>.
</p>
</v-card-text>
</v-card>
</v-col>
</v-row>
<v-row>
Expand Down Expand Up @@ -92,4 +128,10 @@ const Acknowledgements: AcknowledgementsType = {
font-size: 16px;
margin-bottom: 20px;
}

.subtitle {
font-size: 18px;
font-weight: bold;
margin-bottom: 10px;
}
</style>
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