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Mark Duplicate Bitflag & include secondary & Supplimentary Reads #934

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JoeVieira
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Closes #906 & #920

This exposes a few new options

-d Set duplicate bit flag on all non-representative reads
-D representative read strategy, accepts strategies from htslib.
Representative read is chosen by the sum scores ( from the scoring strategy ) across all primary reads, ties are broken with sum of mapping qualities from primary reads.

-S include secondary reads in output ( also mark duplicates on as needed )
-U include supplementary reads in output ( mark as needed )

@JoeVieira
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@tfenne @nh13 feedback welcome.

@tfenne
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tfenne commented Sep 11, 2023

My apologies @JoeVieira - this is definitely on my list to look at, I've just been swamped recently. In all honestly it'll probably be another week or so until I have the time to do a thorough review.

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@tfenne thanks for the response - no worries, appreciate the transparency!

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Use GroupReadsByUmi for standard duplicate marking?
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