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Package: scLANE | ||
Type: Package | ||
Title: Model gene expression over pseudotime with spline-based NB GLMs, GEEs, & GLMMs | ||
Version: 0.6.2 | ||
Title: Model gene expression dynamics with spline-based NB GLMs, GEEs, & GLMMs | ||
Version: 0.7.0 | ||
Authors@R: c(person(given = "Jack", family = "Leary", email = "[email protected]", role = c("aut", "cre")), | ||
person(given = "Rhonda", family = "Bacher", email = "[email protected]", role = c("ctb", "fnd"))) | ||
Description: This package uses truncated power basis spline models to build flexible, interpretable models of single cell gene expression over pseudotime / latent time. Currently supports negative binomial GLMs, GEEs, & GLMMs. | ||
Description: This package uses truncated power basis spline models to build flexible, interpretable models of single cell gene expression over pseudotime or latent time. | ||
The modeling architectures currently supported are negative binomial GLMs, GEEs, & GLMMs. | ||
Downstream analysis functionalities include model comparison, dynamic gene clustering, smoothed counts generation, gene set enrichment testing, & visualization. | ||
License: MIT + file LICENSE | ||
Encoding: UTF-8 | ||
LazyData: true | ||
RoxygenNote: 7.2.1 | ||
Depends: | ||
magrittr, | ||
glm2 | ||
glm2, | ||
magrittr | ||
Imports: | ||
dplyr, | ||
foreach, | ||
doParallel, | ||
parallel, | ||
geeM, | ||
MASS, | ||
ggplot2, | ||
dplyr, | ||
stats, | ||
gamlss, | ||
scales, | ||
splines, | ||
bigstatsr, | ||
broom, | ||
utils, | ||
withr, | ||
purrr, | ||
tidyr, | ||
geeM, | ||
glmmTMB, | ||
broom.mixed, | ||
tidyselect, | ||
furrr, | ||
gamlss, | ||
scales, | ||
future, | ||
ggplot2, | ||
splines, | ||
foreach, | ||
glmmTMB, | ||
parallel, | ||
bigstatsr, | ||
RcppEigen, | ||
doParallel, | ||
tidyselect, | ||
broom.mixed, | ||
Rcpp (>= 1.0.7) | ||
URL: https://github.com/jr-leary7/scLANE | ||
BugReports: https://github.com/jr-leary7/scLANE/issues | ||
Suggests: | ||
rmarkdown, | ||
knitr, | ||
testthat (>= 3.0.0), | ||
covr, | ||
ggh4x, | ||
knitr, | ||
irlba, | ||
rlang, | ||
igraph, | ||
Seurat, | ||
bluster, | ||
cluster, | ||
clusterProfiler, | ||
igraph, | ||
irlba, | ||
slingshot, | ||
msigdbr, | ||
rmarkdown, | ||
slingshot, | ||
BiocGenerics, | ||
BiocNeighbors, | ||
rlang, | ||
Seurat, | ||
clusterProfiler, | ||
testthat (>= 3.0.0), | ||
SingleCellExperiment, | ||
SummarizedExperiment, | ||
BiocGenerics | ||
SummarizedExperiment | ||
VignetteBuilder: knitr | ||
Config/testthat/edition: 3 | ||
LinkingTo: | ||
RcppEigen, | ||
Rcpp | ||
Rcpp, | ||
RcppEigen | ||
biocViews: | ||
RNASeq, | ||
Software, | ||
TimeCourse, | ||
Sequencing, | ||
Regression, | ||
SingleCell, | ||
Visualization, | ||
GeneExpression, | ||
Transcriptomics, | ||
DifferentialExpression |
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