Skip to content

Commit

Permalink
Update docs/output.md
Browse files Browse the repository at this point in the history
Co-authored-by: Maxime U Garcia <[email protected]>
  • Loading branch information
lindenb and maxulysse authored Sep 3, 2024
1 parent cdd529d commit 04086cd
Showing 1 changed file with 5 additions and 5 deletions.
10 changes: 5 additions & 5 deletions docs/output.md
Original file line number Diff line number Diff line change
Expand Up @@ -573,17 +573,17 @@ For further downstream analysis, take a look [here](https://github.com/Illumina/

### Structural Variants

#### Indexcov
#### indexcov

[Indexcov](https://github.com/brentp/goleft/tree/master/indexcov) quickly estimate coverage from a whole-genome bam or cram index.
[indexcov](https://github.com/brentp/goleft/tree/master/indexcov) quickly estimate coverage from a whole-genome bam or cram index.
A bam index has 16KB resolution and it is used as a coverage estimate .
The output is scaled to around 1. So a long stretch with values of 1.5 would be a heterozygous duplication. This is useful as a quick QC to get coverage values across the genome.

**Output directory: `{outdir}/variantcalling/indexcov/`**

In addition to the interactive HTML files, `indexcov` outputs a number of text files:

- `$prefix-indexcov.ped`: a .ped/.fam file with the inferred sex in the appropriate column if the sex chromosomes were found.
- `<sample>-indexcov.ped`: a .ped/.fam file with the inferred sex in the appropriate column if the sex chromosomes were found.
the CNX and CNY columns indicating the floating-point estimate of copy-number for those chromosomes.
`bins.out`: how many bins had a coverage value outside of (0.85, 1.15). high values can indicate high-bias samples.
`bins.lo`: number of bins with value < 0.15. high values indicate missing data.
Expand All @@ -592,9 +592,9 @@ In addition to the interactive HTML files, `indexcov` outputs a number of text f
`p.out`: `bins.out/bins.in`
`PC1...PC5`: PCA projections calculated with depth of autosomes.

- `$prefix-indexcov.roc`: tab-delimited columns of chrom, scaled coverage cutoff, and $n_samples columns where each indicates the
- `<sample>-indexcov.roc`: tab-delimited columns of chrom, scaled coverage cutoff, and $n_samples columns where each indicates the
proportion of 16KB blocks at or above that scaled coverage value.
- `$prefix-indexcov.bed.gz`: a bed file with columns of chrom, start, end, and a column per sample where the values indicate there
- `<sample>-indexcov.bed.gz`: a bed file with columns of chrom, start, end, and a column per sample where the values indicate there
scaled coverage for that sample in that 16KB chunk.

#### Manta
Expand Down

0 comments on commit 04086cd

Please sign in to comment.