VEP 97.3

• vcf2maf improvements
• other bug fixes
• Data bundle updates

Added Cancer_NOS

v0.8.1

0.8.1 release

Bundle update + OpenTargets

• data bundle updates
• inclusion of OpenTargets association scores
• inclusion of TCGA distributions for mutational burden
• inclusion of more options for tumor-only variant filtering

Data bundle update and bug fixes

v0.7.0

0.7.0

Minor CNA bug

v0.6.2.1

0.6.2.1 release

GRCh38 and copy number annotation

Fixed various bugs reported by users

• grch38 support for mutational signature analysis
• copy number annotation
• filtering stats shown in tumor-only option

0.6.2 also comes with updated data bundle.

Thanks to valuable contributions/testing by @vladsaveliev, @zacshi, @shukwong, @patidarr

Tier assignment fix

• Fixed reported bugs in tier assignment of variants

Python3 + grch38

• Updated data sources
• Enabling specification of tumor type of input sample
• New tier system for classification of variants (ACMG-like)
• VCF validation can be turned off
• Tumor DP/AF presets
• JSON dump of report content
• GRCh38 support
• Runs under Python3

Option fix

Corrects a bug with propagation of default options

v0.5.2

0.5.2 release