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Added some more introductory text and an image of the Steno Centres i…
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…n Denmark, Greenland and Faroe Islands
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danielwitte authored Jun 4, 2024
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Expand Up @@ -35,3 +35,18 @@ The past decades have brought a lot of new opportunities for diabetes prevention
* Expanding evidence for substantial heterogeneity in (pre)diabetes and diabetes risk
* Advanced technology for real time measurements (CGM, sleep, physical activity)
* Widespread adoption of communication via smartphones and use of apps

## What will DP-Next do?
We aim to use these developments to design and deliver a sustainably effective strategy for prevention of T2D in Denmark, Greenland and the Faroe Islands.

We will work towards this aim in four Work Packages (WP) across all seven Steno Diabetes Centres:

![There are 5 Steno Diabetes Centers in Denmark, one in Greenland and one on the Faroe Islands.](./images/DK_map_SDC.jpg)

WP1 (Management and Collaboration) will manage the project and foster deep collaboration between all partners.

WP2 (Risk Prediction) will develop an exclusively register-based diabetes risk prediction model for the entire Danish, Greenlandic and Faroese populations, applying advanced statistical and machine learning approaches on a wide set of risk indicators. It will map out meaningful subgroups and validate internally and in external populations.
WP3 (Heterogeneity) will map out heterogeneity in T2D risk in a subgroup of ~1000 participants with HbA1c-based pre-diabetes with a special focus on regional fat distribution, hepatic steatosis and insulin resistance.
WP4 (Intervention Development) will develop an intervention for sustainable primary diabetes prevention based on co-creation, a systems approach and the “Complex Interventions” framework and evaluate the pragmatic feasibility of intervention components in two risk subgroups in real life practical settings.


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