You signed in with another tab or window. Reload to refresh your session.You signed out in another tab or window. Reload to refresh your session.You switched accounts on another tab or window. Reload to refresh your session.Dismiss alert
Updated the crate for CYP2D6 generation, improving alignment offset seeding and reducing over-splitting for shorter reads (e.g., targeted sequencing)
Added a secondary penalty for using a non-unique chain pair during the CYP2D6 chaining step. This tends to reduce errors caused by ambiguous chains in WGS datasets.
Fixed
Fixed an issue with CYP2D6 where an "UNKNOWN" cluster could erroneously generate an extra allele when two defined alleles came from the same HPC-cluster
Fixed an issue with CYP2D6 where alleles excluding from normalization could form their own unpenalized haplotype (e.g., a *68 allele by itself)
Fixed a panic caused by typing an empty CYP2D6 sequence
Fixed a panic caused by no usable reads in the CYP2D6 search region