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Releases: cbg-ethz/PYggdrasil

v0.2.0

19 Oct 12:07
@gordonkoehn gordonkoehn
v0.2.0
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PYggdrasil v0.2.0 Release Notes

PYggdrasil v0.2.0 implements the Single Cell Inference of Tumor Evolution (SCITE) algortihm by Kuipers J et al. (2015).

It was designed to quantify the Markov chain Monte Carlo exploration of tumour progression tree spaces, in particular to investigate:

  • Initialisation Strategies
  • Convergence Diagnostics
  • Multi-modalities

Although PYggdrasil doesn't currently implement all features of SCITE, it enables running complex snakemake workflows for reproducible experiments.

This version allows to reproduce all experiments conducted in Gordon J Köhn's MSc Thesis: Quantifying MCMC Exploration of Tumour Progression Tree Spaces.

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